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| 80. Nishimori I, Minakuchi T, Onishi S, Vullo D, Scozzafava A, Supuran CT.. (2007) Carbonic anhydrase inhibitors. DNA cloning, characterization, and inhibition studies of the human secretory isoform VI, a new target for sulfonamide and sulfamate inhibitors., 50 (2): [PMID:17228881] [10.1021/jm0612057] |
| 81. Wilkinson BL, Bornaghi LF, Houston TA, Innocenti A, Vullo D, Supuran CT, Poulsen SA.. (2007) Carbonic anhydrase inhibitors: inhibition of isozymes I, II, and IX with triazole-linked O-glycosides of benzene sulfonamides., 50 (7): [PMID:17343373] [10.1021/jm061320h] |
| 82. Nuti E, Orlandini E, Nencetti S, Rossello A, Innocenti A, Scozzafava A, Supuran CT.. (2007) Carbonic anhydrase and matrix metalloproteinase inhibitors. Inhibition of human tumor-associated isozymes IX and cytosolic isozyme I and II with sulfonylated hydroxamates., 15 (6): [PMID:17276072] [10.1016/j.bmc.2007.01.023] |
| 83. Huber VJ, Tsujita M, Yamazaki M, Sakimura K, Nakada T.. (2007) Identification of arylsulfonamides as Aquaporin 4 inhibitors., 17 (5): [PMID:17178220] [10.1016/j.bmcl.2006.12.010] |
| 84. Wilkinson BL, Bornaghi LF, Houston TA, Innocenti A, Vullo D, Supuran CT, Poulsen SA.. (2007) Inhibition of membrane-associated carbonic anhydrase isozymes IX, XII and XIV with a library of glycoconjugate benzenesulfonamides., 17 (4): [PMID:17157501] [10.1016/j.bmcl.2006.11.046] |
| 85. Santos MA, Marques S, Vullo D, Innocenti A, Scozzafava A, Supuran CT.. (2007) Carbonic anhydrase inhibitors: inhibition of cytosolic/tumor-associated isoforms I, II, and IX with iminodiacetic carboxylates/hydroxamates also incorporating benzenesulfonamide moieties., 17 (6): [PMID:17251018] [10.1016/j.bmcl.2006.12.107] |
| 86. Winum JY, Thiry A, Cheikh KE, Dogné JM, Montero JL, Vullo D, Scozzafava A, Masereel B, Supuran CT.. (2007) Carbonic anhydrase inhibitors. Inhibition of isoforms I, II, IV, VA, VII, IX, and XIV with sulfonamides incorporating fructopyranose-thioureido tails., 17 (10): [PMID:17376683] [10.1016/j.bmcl.2007.03.008] |
| 87. Nishimori I, Minakuchi T, Kohsaki T, Onishi S, Takeuchi H, Vullo D, Scozzafava A, Supuran CT.. (2007) Carbonic anhydrase inhibitors: the beta-carbonic anhydrase from Helicobacter pylori is a new target for sulfonamide and sulfamate inhibitors., 17 (13): [PMID:17482815] [10.1016/j.bmcl.2007.04.063] |
| 88. Alterio V, De Simone G, Monti SM, Scozzafava A, Supuran CT.. (2007) Carbonic anhydrase inhibitors: inhibition of human, bacterial, and archaeal isozymes with benzene-1,3-disulfonamides--solution and crystallographic studies., 17 (15): [PMID:17540563] [10.1016/j.bmcl.2007.05.045] |
| 89. Smaine FZ, Winum JY, Montero JL, Regainia Z, Vullo D, Scozzafava A, Supuran CT.. (2007) Carbonic anhydrase inhibitors: Selective inhibition of the extracellular, tumor-associated isoforms IX and XII over isozymes I and II with glycosyl-thioureido-sulfonamides., 17 (18): [PMID:17646100] [10.1016/j.bmcl.2007.07.019] |
| 90. Colinas PA, Bravo RD, Vullo D, Scozzafava A, Supuran CT.. (2007) Carbonic anhydrase inhibitors. Inhibition of cytosolic isoforms I and II, and extracellular isoforms IV, IX, and XII with sulfamides incorporating sugar moieties., 17 (18): [PMID:17658252] [10.1016/j.bmcl.2007.07.023] |
| 91. Salmon AJ, Williams ML, Innocenti A, Vullo D, Supuran CT, Poulsen SA.. (2007) Inhibition of carbonic anhydrase isozymes I, II and IX with benzenesulfonamides containing an organometallic moiety., 17 (18): [PMID:17681760] [10.1016/j.bmcl.2007.07.024] |
| 92. Abdel-Hamid MK, Abdel-Hafez AA, El-Koussi NA, Mahfouz NM, Innocenti A, Supuran CT.. (2007) Design, synthesis, and docking studies of new 1,3,4-thiadiazole-2-thione derivatives with carbonic anhydrase inhibitory activity., 15 (22): [PMID:17822907] [10.1016/j.bmc.2007.07.044] |
| 93. Nishimori I, Minakuchi T, Onishi S, Vullo D, Cecchi A, Scozzafava A, Supuran CT.. (2007) Carbonic anhydrase inhibitors: cloning, characterization, and inhibition studies of the cytosolic isozyme III with sulfonamides., 15 (23): [PMID:17826101] [10.1016/j.bmc.2007.08.037] |
| 94. Nishimori I, Innocenti A, Vullo D, Scozzafava A, Supuran CT.. (2007) Carbonic anhydrase inhibitors. Inhibition studies of the human secretory isoform VI with anions., 17 (4): [PMID:17127063] [10.1016/j.bmcl.2006.11.028] |
| 95. Nishimori I, Onishi S, Vullo D, Innocenti A, Scozzafava A, Supuran CT.. (2007) Carbonic anhydrase activators: the first activation study of the human secretory isoform VI with amino acids and amines., 15 (15): [PMID:17499996] [10.1016/j.bmc.2007.03.004] |
| 96. Supuran CT, Scozzafava A.. (2007) Carbonic anhydrases as targets for medicinal chemistry., 15 (13): [PMID:17475500] [10.1016/j.bmc.2007.04.020] |
| 97. Innocenti A, Hilvo M, Scozzafava A, Lindfors M, Nordlund HR, Kulomaa MS, Parkkila S, Supuran CT.. (2008) Carbonic anhydrase inhibitors: the very weak inhibitors dithiothreitol, beta-mercaptoethanol, tris(carboxyethyl)phosphine and threitol interfere with the binding of sulfonamides to isozymes II and IX., 18 (6): [PMID:18295485] [10.1016/j.bmcl.2008.02.008] |
| 98. Innocenti A, Scozzafava A, Parkkila S, Puccetti L, De Simone G, Supuran CT.. (2008) Investigations of the esterase, phosphatase, and sulfatase activities of the cytosolic mammalian carbonic anhydrase isoforms I, II, and XIII with 4-nitrophenyl esters as substrates., 18 (7): [PMID:18353640] [10.1016/j.bmcl.2008.03.012] |
| 99. Innocenti A, Vullo D, Scozzafava A, Supuran CT.. (2008) Carbonic anhydrase inhibitors: interactions of phenols with the 12 catalytically active mammalian isoforms (CA I-XIV)., 18 (5): [PMID:18242985] [10.1016/j.bmcl.2008.01.077] |
| 100. Wilkinson BL, Innocenti A, Vullo D, Supuran CT, Poulsen SA.. (2008) Inhibition of carbonic anhydrases with glycosyltriazole benzene sulfonamides., 51 (6): [PMID:18307288] [10.1021/jm701426t] |
| 101. Temperini C, Cecchi A, Boyle NA, Scozzafava A, Cabeza JE, Wentworth P, Blackburn GM, Supuran CT.. (2008) Carbonic anhydrase inhibitors. Interaction of 2-N,N-dimethylamino-1,3,4-thiadiazole-5-methanesulfonamide with 12 mammalian isoforms: kinetic and X-ray crystallographic studies., 18 (3): [PMID:18162396] [10.1016/j.bmcl.2007.12.022] |
| 102. Rami M, Winum JY, Innocenti A, Montero JL, Scozzafava A, Supuran CT.. (2008) Carbonic anhydrase inhibitors: copper(II) complexes of polyamino-polycarboxylamido aromatic/heterocyclic sulfonamides are very potent inhibitors of the tumor-associated isoforms IX and XII., 18 (2): [PMID:18042384] [10.1016/j.bmcl.2007.11.025] |
| 103. Di Fiore A, Pedone C, Antel J, Waldeck H, Witte A, Wurl M, Scozzafava A, Supuran CT, De Simone G.. (2008) Carbonic anhydrase inhibitors: the X-ray crystal structure of ethoxzolamide complexed to human isoform II reveals the importance of thr200 and gln92 for obtaining tight-binding inhibitors., 18 (8): [PMID:18359629] [10.1016/j.bmcl.2008.03.023] |
| 104. Temperini C, Cecchi A, Scozzafava A, Supuran CT.. (2008) Carbonic anhydrase inhibitors. Interaction of indapamide and related diuretics with 12 mammalian isozymes and X-ray crystallographic studies for the indapamide-isozyme II adduct., 18 (8): [PMID:18374572] [10.1016/j.bmcl.2008.03.051] |
| 105. Innocenti A, Hilvo M, Scozzafava A, Parkkila S, Supuran CT.. (2008) Carbonic anhydrase inhibitors: Inhibition of the new membrane-associated isoform XV with phenols., 18 (12): [PMID:18501600] [10.1016/j.bmcl.2008.04.077] |
| 106. Cecchi A, Ciani L, Winum JY, Montero JL, Scozzafava A, Ristori S, Supuran CT.. (2008) Carbonic anhydrase inhibitors: design of spin-labeled sulfonamides incorporating TEMPO moieties as probes for cytosolic or transmembrane isozymes., 18 (12): [PMID:18513964] [10.1016/j.bmcl.2008.05.051] |
| 107. Saczewski F, Innocenti A, Sławiński J, Kornicka A, Brzozowski Z, Pomarnacka E, Scozzafava A, Temperini C, Supuran CT.. (2008) Carbonic anhydrase inhibitors: inhibition of human cytosolic isozymes I and II and tumor-associated isozymes IX and XII with S-substituted 4-chloro-2-mercapto-5-methyl-benzenesulfonamides., 16 (7): [PMID:18242998] [10.1016/j.bmc.2008.01.034] |
| 108. Isik S, Kockar F, Arslan O, Guler OO, Innocenti A, Supuran CT.. (2008) Carbonic anhydrase inhibitors. Inhibition of the beta-class enzyme from the yeast Saccharomyces cerevisiae with anions., 18 (24): [PMID:18993072] [10.1016/j.bmcl.2008.10.100] |
| 109. Marques SM, Nuti E, Rossello A, Supuran CT, Tuccinardi T, Martinelli A, Santos MA.. (2008) Dual inhibitors of matrix metalloproteinases and carbonic anhydrases: iminodiacetyl-based hydroxamate-benzenesulfonamide conjugates., 51 (24): [PMID:19053764] [10.1021/jm800964f] |
| 110. Huber VJ, Tsujita M, Kwee IL, Nakada T.. (2009) Inhibition of aquaporin 4 by antiepileptic drugs., 17 (1): [PMID:18178093] [10.1016/j.bmc.2007.12.038] |
| 111. Santana L, González-Díaz H, Quezada E, Uriarte E, Yáñez M, Viña D, Orallo F.. (2008) Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors., 51 (21): [PMID:18834112] [10.1021/jm800656v] |
| 112. Thiry A, Ledecq M, Cecchi A, Frederick R, Dogné JM, Supuran CT, Wouters J, Masereel B.. (2009) Ligand-based and structure-based virtual screening to identify carbonic anhydrase IX inhibitors., 17 (2): [PMID:19097911] [10.1016/j.bmc.2008.11.071] |
| 113. Crocetti L, Maresca A, Temperini C, Hall RA, Scozzafava A, Mühlschlegel FA, Supuran CT.. (2009) A thiabendazole sulfonamide shows potent inhibitory activity against mammalian and nematode alpha-carbonic anhydrases., 19 (5): [PMID:19186056] [10.1016/j.bmcl.2009.01.038] |
| 114. Granero GE, Maitre MM, Garnero C, Longhi MR.. (2008) Synthesis, characterization and in vitro release studies of a new acetazolamide-HP-beta-CD-TEA inclusion complex., 43 (3): [PMID:17544174] [10.1016/j.ejmech.2007.03.037] |
| 115. Innocenti A, Maresca A, Scozzafava A, Supuran CT.. (2008) Carbonic anhydrase inhibitors: thioxolone versus sulfonamides for obtaining isozyme-selective inhibitors?, 18 (14): [PMID:18572406] [10.1016/j.bmcl.2008.06.024] |
| 116. Temperini C, Cecchi A, Scozzafava A, Supuran CT.. (2009) Carbonic anhydrase inhibitors. Comparison of chlorthalidone, indapamide, trichloromethiazide, and furosemide X-ray crystal structures in adducts with isozyme II, when several water molecules make the difference., 17 (3): [PMID:19119014] [10.1016/j.bmc.2008.12.023] |
| 117. Bertucci A, Innocenti A, Zoccola D, Scozzafava A, Allemand D, Tambutté S, Supuran CT.. (2009) Carbonic anhydrase inhibitors: inhibition studies of a coral secretory isoform with inorganic anions., 19 (3): [PMID:19121582] [10.1016/j.bmcl.2008.12.056] |
| 118. Isik S, Kockar F, Aydin M, Arslan O, Guler OO, Innocenti A, Scozzafava A, Supuran CT.. (2009) Carbonic anhydrase inhibitors: inhibition of the beta-class enzyme from the yeast Saccharomyces cerevisiae with sulfonamides and sulfamates., 17 (3): [PMID:19124253] [10.1016/j.bmc.2008.12.035] |
| 119. Smaine FZ, Pacchiano F, Rami M, Barragan-Montero V, Vullo D, Scozzafava A, Winum JY, Supuran CT.. (2008) Carbonic anhydrase inhibitors: 2-substituted-1,3,4-thiadiazole-5-sulfamides act as powerful and selective inhibitors of the mitochondrial isozymes VA and VB over the cytosolic and membrane-associated carbonic anhydrases I, II and IV., 18 (24): [PMID:18990571] [10.1016/j.bmcl.2008.10.093] |
| 120. Güzel O, Maresca A, Scozzafava A, Salman A, Balaban AT, Supuran CT.. (2009) Discovery of low nanomolar and subnanomolar inhibitors of the mycobacterial beta-carbonic anhydrases Rv1284 and Rv3273., 52 (13): [PMID:19438226] [10.1021/jm9004016] |
| 121. Güzel O, Maresca A, Scozzafava A, Salman A, Balaban AT, Supuran CT.. (2009) Carbonic anhydrase inhibitors. Synthesis of 2,4,6-trimethylpyridinium derivatives of 2-(hydrazinocarbonyl)-3-aryl-1H-indole-5-sulfonamides acting as potent inhibitors of the tumor-associated isoform IX and XII., 19 (11): [PMID:19410461] [10.1016/j.bmcl.2009.04.068] |
| 122. Kasimoğullari R, Bülbül M, Günhan H, Güleryüz H.. (2009) Effects of new 5-amino-1,3,4-thiadiazole-2-sulfonamide derivatives on human carbonic anhydrase isozymes., 17 (9): [PMID:19362844] [10.1016/j.bmc.2009.03.048] |
| 123. Temperini C, Innocenti A, Scozzafava A, Supuran CT.. (2008) Carbonic anhydrase inhibitors. Interaction of the antitumor sulfamate EMD 486019 with twelve mammalian carbonic anhydrase isoforms: Kinetic and X-ray crystallographic studies., 18 (15): [PMID:18640037] [10.1016/j.bmcl.2008.06.105] |
| 124. Yang B, Zhang H, Verkman AS.. (2008) Lack of aquaporin-4 water transport inhibition by antiepileptics and arylsulfonamides., 16 (15): [PMID:18572411] [10.1016/j.bmc.2008.06.005] |
| 125. Innocenti A, Vullo D, Scozzafava A, Supuran CT.. (2008) Carbonic anhydrase inhibitors: inhibition of mammalian isoforms I-XIV with a series of substituted phenols including paracetamol and salicylic acid., 16 (15): [PMID:18579385] [10.1016/j.bmc.2008.06.013] |
| 126. Krungkrai J, Krungkrai SR, Supuran CT.. (2008) Carbonic anhydrase inhibitors: inhibition of Plasmodium falciparum carbonic anhydrase with aromatic/heterocyclic sulfonamides-in vitro and in vivo studies., 18 (20): [PMID:18805693] [10.1016/j.bmcl.2008.09.030] |
| 127. Innocenti A, Mühlschlegel FA, Hall RA, Steegborn C, Scozzafava A, Supuran CT.. (2008) Carbonic anhydrase inhibitors: inhibition of the beta-class enzymes from the fungal pathogens Candida albicans and Cryptococcus neoformans with simple anions., 18 (18): [PMID:18723348] [10.1016/j.bmcl.2008.07.122] |
| 128. Temperini C, Cecchi A, Scozzafava A, Supuran CT.. (2009) Carbonic anhydrase inhibitors. Comparison of chlorthalidone and indapamide X-ray crystal structures in adducts with isozyme II: when three water molecules and the keto-enol tautomerism make the difference., 52 (2): [PMID:19115843] [10.1021/jm801386n] |
| 129. Thiry A, Rolin S, Vullo D, Frankart A, Scozzafava A, Dogné JM, Wouters J, Supuran CT, Masereel B.. (2008) Indanesulfonamides as carbonic anhydrase inhibitors and anticonvulsant agents: structure-activity relationship and pharmacological evaluation., 43 (12): [PMID:18406497] [10.1016/j.ejmech.2008.02.018] |
| 130. Hilvo M, Salzano AM, Innocenti A, Kulomaa MS, Scozzafava A, Scaloni A, Parkkila S, Supuran CT.. (2009) Cloning, expression, post-translational modifications and inhibition studies on the latest mammalian carbonic anhydrase isoform, CA XV., 52 (3): [PMID:19193158] [10.1021/jm801267c] |
| 131. Sentürk M, Gülçin I, Daştan A, Küfrevioğlu OI, Supuran CT.. (2009) Carbonic anhydrase inhibitors. Inhibition of human erythrocyte isozymes I and II with a series of antioxidant phenols., 17 (8): [PMID:19231207] [10.1016/j.bmc.2009.01.067] |
| 132. Güzel O, Innocenti A, Hall RA, Scozzafava A, Mühlschlegel FA, Supuran CT.. (2009) Carbonic anhydrase inhibitors. The nematode alpha-carbonic anhydrase of Caenorhabditis elegans CAH-4b is highly inhibited by 2-(hydrazinocarbonyl)-3-substituted-phenyl-1H-indole-5-sulfonamides., 17 (8): [PMID:19201197] [10.1016/j.bmc.2009.01.048] |
| 133. Thiry A, Delayen A, Goossens L, Houssin R, Ledecq M, Frankart A, Dogné JM, Wouters J, Supuran CT, Hénichart JP, Masereel B.. (2009) Synthesis and biological evaluation of a new family of anti-benzylanilinosulfonamides as CA IX inhibitors., 44 (2): [PMID:18479784] [10.1016/j.ejmech.2008.03.034] |
| 134. Minakuchi T, Nishimori I, Vullo D, Scozzafava A, Supuran CT.. (2009) Molecular cloning, characterization, and inhibition studies of the Rv1284 beta-carbonic anhydrase from Mycobacterium tuberculosis with sulfonamides and a sulfamate., 52 (8): [PMID:19317447] [10.1021/jm9000488] |
| 135. D'Ambrosio K, Vitale RM, Dogné JM, Masereel B, Innocenti A, Scozzafava A, De Simone G, Supuran CT.. (2008) Carbonic anhydrase inhibitors: bioreductive nitro-containing sulfonamides with selectivity for targeting the tumor associated isoforms IX and XII., 51 (11): [PMID:18481843] [10.1021/jm800121c] |
| 136. Nishimori I, Minakuchi T, Vullo D, Scozzafava A, Innocenti A, Supuran CT.. (2009) Carbonic anhydrase inhibitors. Cloning, characterization, and inhibition studies of a new beta-carbonic anhydrase from Mycobacterium tuberculosis., 52 (9): [PMID:19338333] [10.1021/jm9003126] |
| 137. Singer M, Lopez M, Bornaghi LF, Innocenti A, Vullo D, Supuran CT, Poulsen SA.. (2009) Inhibition of carbonic anhydrase isozymes with benzene sulfonamides incorporating thio, sulfinyl and sulfonyl glycoside moieties., 19 (8): [PMID:19286378] [10.1016/j.bmcl.2009.02.086] |
| 138. Nasr G, Petit E, Vullo D, Winum JY, Supuran CT, Barboiu M.. (2009) Carbonic anhydrase-encoded dynamic constitutional libraries: toward the discovery of isozyme-specific inhibitors., 52 (15): [PMID:19580287] [10.1021/jm900449v] |
| 139. Innocenti A, Winum JY, Hall RA, Mühlschlegel FA, Scozzafava A, Supuran CT.. (2009) Carbonic anhydrase inhibitors. Inhibition of the fungal beta-carbonic anhydrases from Candida albicans and Cryptococcus neoformans with boronic acids., 19 (10): [PMID:19375309] [10.1016/j.bmcl.2009.03.147] |
| 140. Varma MV, Feng B, Obach RS, Troutman MD, Chupka J, Miller HR, El-Kattan A.. (2009) Physicochemical determinants of human renal clearance., 52 (15): [PMID:19445515] [10.1021/jm900403j] |
| 141. Parkkila S, Innocenti A, Kallio H, Hilvo M, Scozzafava A, Supuran CT.. (2009) The protein tyrosine kinase inhibitors imatinib and nilotinib strongly inhibit several mammalian alpha-carbonic anhydrase isoforms., 19 (15): [PMID:19527930] [10.1016/j.bmcl.2009.06.002] |
| 142. Innocenti A, Hall RA, Schlicker C, Scozzafava A, Steegborn C, Mühlschlegel FA, Supuran CT.. (2009) Carbonic anhydrase inhibitors. Inhibition and homology modeling studies of the fungal beta-carbonic anhydrase from Candida albicans with sulfonamides., 17 (13): [PMID:19450983] [10.1016/j.bmc.2009.05.002] |
| 143. Innocenti A, Leewattanapasuk W, Mühlschlegel FA, Mastrolorenzo A, Supuran CT.. (2009) Carbonic anhydrase inhibitors. Inhibition of the beta-class enzyme from the pathogenic yeast Candida glabrata with anions., 19 (16): [PMID:19574046] [10.1016/j.bmcl.2009.06.048] |
| 144. Bertucci A, Innocenti A, Zoccola D, Scozzafava A, Tambutté S, Supuran CT.. (2009) Carbonic anhydrase inhibitors. Inhibition studies of a coral secretory isoform by sulfonamides., 17 (14): [PMID:19520577] [10.1016/j.bmc.2009.05.063] |
| 145. Güzel O, Innocenti A, Scozzafava A, Salman A, Supuran CT.. (2009) Carbonic anhydrase inhibitors. Aromatic/heterocyclic sulfonamides incorporating phenacetyl, pyridylacetyl and thienylacetyl tails act as potent inhibitors of human mitochondrial isoforms VA and VB., 17 (14): [PMID:19539481] [10.1016/j.bmc.2009.06.006] |
| 146. Carta F, Maresca A, Covarrubias AS, Mowbray SL, Jones TA, Supuran CT.. (2009) Carbonic anhydrase inhibitors. Characterization and inhibition studies of the most active beta-carbonic anhydrase from Mycobacterium tuberculosis, Rv3588c., 19 (23): [PMID:19846301] [10.1016/j.bmcl.2009.10.009] |
| 147. Vitale RM, Alterio V, Innocenti A, Winum JY, Monti SM, De Simone G, Supuran CT.. (2009) Carbonic anhydrase inhibitors. Comparison of aliphatic sulfamate/bis-sulfamate adducts with isozymes II and IX as a platform for designing tight-binding, more isoform-selective inhibitors., 52 (19): [PMID:19731956] [10.1021/jm900641r] |
| 148. Lopez M, Paul B, Hofmann A, Morizzi J, Wu QK, Charman SA, Innocenti A, Vullo D, Supuran CT, Poulsen SA.. (2009) S-glycosyl primary sulfonamides--a new structural class for selective inhibition of cancer-associated carbonic anhydrases., 52 (20): [PMID:19827837] [10.1021/jm900914e] |
| 149. Temperini C, Innocenti A, Scozzafava A, Parkkila S, Supuran CT.. (2010) The coumarin-binding site in carbonic anhydrase accommodates structurally diverse inhibitors: the antiepileptic lacosamide as an example and lead molecule for novel classes of carbonic anhydrase inhibitors., 53 (2): [PMID:20028100] [10.1021/jm901524f] |
| 150. Maresca A, Carta F, Vullo D, Scozzafava A, Supuran CT.. (2009) Carbonic anhydrase inhibitors. Inhibition of the Rv1284 and Rv3273 beta-carbonic anhydrases from Mycobacterium tuberculosis with diazenylbenzenesulfonamides., 19 (17): [PMID:19651511] [10.1016/j.bmcl.2009.07.088] |
| 151. Innocenti A, Pastorekova S, Pastorek J, Scozzafava A, De Simone G, Supuran CT.. (2009) The proteoglycan region of the tumor-associated carbonic anhydrase isoform IX acts as anintrinsic buffer optimizing CO2 hydration at acidic pH values characteristic of solid tumors., 19 (20): [PMID:19751975] [10.1016/j.bmcl.2009.08.088] |
| 152. Carta F, Maresca A, Scozzafava A, Vullo D, Supuran CT.. (2009) Carbonic anhydrase inhibitors. Diazenylbenzenesulfonamides are potent and selective inhibitors of the tumor-associated isozymes IX and XII over the cytosolic isoforms I and II., 17 (20): [PMID:19773173] [10.1016/j.bmc.2009.09.003] |
| 153. Joseph P, Turtaut F, Ouahrani-Bettache S, Montero JL, Nishimori I, Minakuchi T, Vullo D, Scozzafava A, Köhler S, Winum JY, Supuran CT.. (2010) Cloning, characterization, and inhibition studies of a beta-carbonic anhydrase from Brucella suis., 53 (5): [PMID:20158185] [10.1021/jm901855h] |
| 154. Innocenti A, Beyza Oztürk Sarikaya S, Gülçin I, Supuran CT.. (2010) Carbonic anhydrase inhibitors. Inhibition of mammalian isoforms I-XIV with a series of natural product polyphenols and phenolic acids., 18 (6): [PMID:20185318] [10.1016/j.bmc.2010.01.076] |
| 155. Davis RA, Innocenti A, Poulsen SA, Supuran CT.. (2010) Carbonic anhydrase inhibitors. Identification of selective inhibitors of the human mitochondrial isozymes VA and VB over the cytosolic isozymes I and II from a natural product-based phenolic library., 18 (1): [PMID:19962903] [10.1016/j.bmc.2009.11.021] |
| 156. Yenikaya C, Sari M, Bülbül M, Ilkimen H, Celik H, Büyükgüngör O.. (2010) Synthesis, characterization and antiglaucoma activity of a novel proton transfer compound and a mixed-ligand Zn(II) complex., 18 (2): [PMID:20006931] [10.1016/j.bmc.2009.11.031] |
| 157. Benfodda Z, Guillen F, Romestand B, Dahmani A, Blancou H.. (2010) Synthesis and investigation of inhibition effect of fluorinated sulfonamide derivatives on carbonic anhydrase., 45 (3): [PMID:20036446] [10.1016/j.ejmech.2009.11.052] |
| 158. Oltulu O, Yaşar MM, Eroğlu E.. (2009) A QSAR study on relationship between structure of sulfonamides and their carbonic anhydrase inhibitory activity using the eigenvalue (EVA) method., 44 (9): [PMID:19303173] [10.1016/j.ejmech.2009.02.016] |
| 159. Gitto R, Agnello S, Ferro S, De Luca L, Vullo D, Brynda J, Mader P, Supuran CT, Chimirri A.. (2010) Identification of 3,4-Dihydroisoquinoline-2(1H)-sulfonamides as potent carbonic anhydrase inhibitors: synthesis, biological evaluation, and enzyme--ligand X-ray studies., 53 (6): [PMID:20170095] [10.1021/jm9014026] |
| 160. Winum JY, Innocenti A, Vullo D, Montero JL, Supuran CT.. (2009) Carbonic anhydrase inhibitors; fluorinated phenyl sulfamates show strong inhibitory activity and selectivity for the inhibition of the tumor-associated isozymes IX and XII over the cytosolic ones I and II., 19 (17): [PMID:19632111] [10.1016/j.bmcl.2009.07.056] |
| 161. Lopez M, Bornaghi LF, Innocenti A, Vullo D, Charman SA, Supuran CT, Poulsen SA.. (2010) Sulfonamide linked neoglycoconjugates--a new class of inhibitors for cancer-associated carbonic anhydrases., 53 (7): [PMID:20201556] [10.1021/jm901888x] |
| 162. Vullo D, Nishimori I, Scozzafava A, Köhler S, Winum JY, Supuran CT.. (2010) Inhibition studies of a beta-carbonic anhydrase from Brucella suis with a series of water soluble glycosyl sulfanilamides., 20 (7): [PMID:20211561] [10.1016/j.bmcl.2010.02.042] |
| 163. Güzel O, Maresca A, Hall RA, Scozzafava A, Mastrolorenzo A, Mühlschlegel FA, Supuran CT.. (2010) Carbonic anhydrase inhibitors. The beta-carbonic anhydrases from the fungal pathogens Cryptococcus neoformans and Candida albicans are strongly inhibited by substituted-phenyl-1H-indole-5-sulfonamides., 20 (8): [PMID:20299219] [10.1016/j.bmcl.2010.02.103] |
| 164. Esteves MA, Ortet O, Capelo A, Supuran CT, Marques SM, Santos MA.. (2010) New hydroxypyrimidinone-containing sulfonamides as carbonic anhydrase inhibitors also acting as MMP inhibitors., 20 (12): [PMID:20478708] [10.1016/j.bmcl.2010.04.109] |
| 165. Di Fiore A, Monti SM, Innocenti A, Winum JY, De Simone G, Supuran CT.. (2010) Carbonic anhydrase inhibitors: crystallographic and solution binding studies for the interaction of a boron-containing aromatic sulfamide with mammalian isoforms I-XV., 20 (12): [PMID:20472429] [10.1016/j.bmcl.2010.04.114] |
| 166. Alp C, Ekinci D, Gültekin MS, Sentürk M, Sahin E, Küfrevioğlu OI.. (2010) A novel and one-pot synthesis of new 1-tosyl pyrrol-2-one derivatives and analysis of carbonic anhydrase inhibitory potencies., 18 (12): [PMID:20554206] [10.1016/j.bmc.2010.04.072] |
| 167. Brzozowski Z, Sławiński J, Saczewski F, Innocenti A, Supuran CT.. (2010) Carbonic anhydrase inhibitors: synthesis and inhibition of the human cytosolic isozymes I and II and transmembrane isozymes IX, XII (cancer-associated) and XIV with 4-substituted 3-pyridinesulfonamides., 45 (6): [PMID:20202722] [10.1016/j.ejmech.2010.02.020] |
| 168. Wagner J, Avvaru BS, Robbins AH, Scozzafava A, Supuran CT, McKenna R.. (2010) Coumarinyl-substituted sulfonamides strongly inhibit several human carbonic anhydrase isoforms: solution and crystallographic investigations., 18 (14): [PMID:20598552] [10.1016/j.bmc.2010.06.028] |
| 169. Avvaru BS, Wagner JM, Maresca A, Scozzafava A, Robbins AH, Supuran CT, McKenna R.. (2010) Carbonic anhydrase inhibitors. The X-ray crystal structure of human isoform II in adduct with an adamantyl analogue of acetazolamide resides in a less utilized binding pocket than most hydrophobic inhibitors., 20 (15): [PMID:20605094] [10.1016/j.bmcl.2010.06.082] |
| 170. Prado-Prado FJ, García-Mera X, González-Díaz H.. (2010) Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species., 18 (6): [PMID:20185316] [10.1016/j.bmc.2010.01.068] |
| 171. Carta F, Temperini C, Innocenti A, Scozzafava A, Kaila K, Supuran CT.. (2010) Polyamines inhibit carbonic anhydrases by anchoring to the zinc-coordinated water molecule., 53 (15): [PMID:20590092] [10.1021/jm1003667] |
| 172. Kockar F, Maresca A, Aydin M, Işik S, Turkoglu S, Sinan S, Arslan O, Güler OO, Turan Y, Supuran CT.. (2010) Mutation of Phe91 to Asn in human carbonic anhydrase I unexpectedly enhanced both catalytic activity and affinity for sulfonamide inhibitors., 18 (15): [PMID:20624682] [10.1016/j.bmc.2010.06.056] |
| 173. Brzozowski Z, Sławiński J, Innocenti A, Supuran CT.. (2010) Carbonic anhydrase inhibitors. Regioselective synthesis of novel 1-substituted 1,4-dihydro-4-oxo-3-pyridinesulfonamides and their inhibition of the human cytosolic isozymes I and II and transmembrane cancer-associated isozymes IX and XII., 45 (9): [PMID:20554082] [10.1016/j.ejmech.2010.05.011] |
| 174. Gozalbes R, Pineda-Lucena A.. (2010) QSAR-based solubility model for drug-like compounds., 18 (19): [PMID:20810286] [10.1016/j.bmc.2010.08.003] |
| 175. Marques SM, Enyedy EA, Supuran CT, Krupenko NI, Krupenko SA, Santos MA.. (2010) Pteridine-sulfonamide conjugates as dual inhibitors of carbonic anhydrases and dihydrofolate reductase with potential antitumor activity., 18 (14): [PMID:20580561] [10.1016/j.bmc.2010.05.072] |
| 176. Diamandis P, Wildenhain J, Clarke ID, Sacher AG, Graham J, Bellows DS, Ling EK, Ward RJ, Jamieson LG, Tyers M, Dirks PB.. (2007) Chemical genetics reveals a complex functional ground state of neural stem cells., 3 (5): [PMID:17417631] [10.1038/nchembio873] |
| 177. Sūdžius J, Baranauskienė L, Golovenko D, Matulienė J, Michailovienė V, Torresan J, Jachno J, Sukackaitė R, Manakova E, Gražulis S, Tumkevičius S, Matulis D.. (2010) 4-[N-(substituted 4-pyrimidinyl)amino]benzenesulfonamides as inhibitors of carbonic anhydrase isozymes I, II, VII, and XIII., 18 (21): [PMID:20889345] [10.1016/j.bmc.2010.09.011] |
| 178. Kasımoğulları R, Bülbül M, Arslan BS, Gökçe B.. (2010) Synthesis, characterization and antiglaucoma activity of some novel pyrazole derivatives of 5-amino-1,3,4-thiadiazole-2-sulfonamide., 45 (11): [PMID:20724038] [10.1016/j.ejmech.2010.07.041] |
| 179. Schüttelkopf AW, Gros L, Blair DE, Frearson JA, van Aalten DM, Gilbert IH.. (2010) Acetazolamide-based fungal chitinase inhibitors., 18 (23): [PMID:21044846] [10.1016/j.bmc.2010.09.062] |
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| 184. Obach RS, Lombardo F, Waters NJ.. (2008) Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds., 36 (7): [PMID:18426954] [10.1124/dmd.108.020479] |
| 185. Pacchiano F, Carta F, Vullo D, Scozzafava A, Supuran CT.. (2011) Inhibition of β-carbonic anhydrases with ureido-substituted benzenesulfonamides., 21 (1): [PMID:21145236] [10.1016/j.bmcl.2010.11.064] |
| 186. Bertucci A, Innocenti A, Scozzafava A, Tambutté S, Zoccola D, Supuran CT.. (2011) Carbonic anhydrase inhibitors. Inhibition studies with anions and sulfonamides of a new cytosolic enzyme from the scleractinian coral Stylophora pistillata., 21 (2): [PMID:21208801] [10.1016/j.bmcl.2010.11.124] |
| 187. Burghout P, Vullo D, Scozzafava A, Hermans PW, Supuran CT.. (2011) Inhibition of the β-carbonic anhydrase from Streptococcus pneumoniae by inorganic anions and small molecules: Toward innovative drug design of antiinfectives?, 19 (1): [PMID:21163660] [10.1016/j.bmc.2010.11.031] |
| 188. Joseph P, Ouahrani-Bettache S, Montero JL, Nishimori I, Minakuchi T, Vullo D, Scozzafava A, Winum JY, Köhler S, Supuran CT.. (2011) A new β-carbonic anhydrase from Brucella suis, its cloning, characterization, and inhibition with sulfonamides and sulfamates, leading to impaired pathogen growth., 19 (3): [PMID:21251841] [10.1016/j.bmc.2010.12.048] |
| 189. Maresca A, Supuran CT.. (2011) (R)-/(S)-10-camphorsulfonyl-substituted aromatic/heterocyclic sulfonamides selectively inhibit mitochondrial over cytosolic carbonic anhydrases., 21 (5): [PMID:21300547] [10.1016/j.bmcl.2011.01.050] |
| 190. Davis RA, Hofmann A, Osman A, Hall RA, Mühlschlegel FA, Vullo D, Innocenti A, Supuran CT, Poulsen SA.. (2011) Natural product-based phenols as novel probes for mycobacterial and fungal carbonic anhydrases., 54 (6): [PMID:21332115] [10.1021/jm1013242] |
| 191. Pacchiano F, Carta F, McDonald PC, Lou Y, Vullo D, Scozzafava A, Dedhar S, Supuran CT.. (2011) Ureido-substituted benzenesulfonamides potently inhibit carbonic anhydrase IX and show antimetastatic activity in a model of breast cancer metastasis., 54 (6): [PMID:21361354] [10.1021/jm101541x] |
| 192. Cincinelli A, Martellini T, Innocenti A, Scozzafava A, Supuran CT.. (2011) Purification and inhibition studies with anions and sulfonamides of an α-carbonic anhydrase from the Antarctic seal Leptonychotes weddellii., 19 (6): [PMID:21377369] [10.1016/j.bmc.2011.02.015] |
| 193. Greene N, Fisk L, Naven RT, Note RR, Patel ML, Pelletier DJ.. (2010) Developing structure-activity relationships for the prediction of hepatotoxicity., 23 (7): [PMID:20553011] [10.1021/tx1000865] |
| 194. Ekins S, Williams AJ, Xu JJ.. (2010) A predictive ligand-based Bayesian model for human drug-induced liver injury., 38 (12): [PMID:20843939] [10.1124/dmd.110.035113] |
| 195. Fourches D, Barnes JC, Day NC, Bradley P, Reed JZ, Tropsha A.. (2010) Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species., 23 (1): [PMID:20014752] [10.1021/tx900326k] |
| 196. Unpublished dataset, |
| 197. Pala N, Dallocchio R, Dessì A, Brancale A, Carta F, Ihm S, Maresca A, Sechi M, Supuran CT.. (2011) Virtual screening-driven identification of human carbonic anhydrase inhibitors incorporating an original, new pharmacophore., 21 (8): [PMID:21420862] [10.1016/j.bmcl.2011.02.059] |
| 198. Carta F, Innocenti A, Hall RA, Mühlschlegel FA, Scozzafava A, Supuran CT.. (2011) Carbonic anhydrase inhibitors. Inhibition of the β-class enzymes from the fungal pathogens Candida albicans and Cryptococcus neoformans with branched aliphatic/aromatic carboxylates and their derivatives., 21 (8): [PMID:21402476] [10.1016/j.bmcl.2011.02.057] |
| 199. Mader P, Brynda J, Gitto R, Agnello S, Pachl P, Supuran CT, Chimirri A, Řezáčová P.. (2011) Structural basis for the interaction between carbonic anhydrase and 1,2,3,4-tetrahydroisoquinolin-2-ylsulfonamides., 54 (7): [PMID:21395315] [10.1021/jm2000213] |
| 200. Mincione F, Benedini F, Biondi S, Cecchi A, Temperini C, Formicola G, Pacileo I, Scozzafava A, Masini E, Supuran CT.. (2011) Synthesis and crystallographic analysis of new sulfonamides incorporating NO-donating moieties with potent antiglaucoma action., 21 (11): [PMID:21549597] [10.1016/j.bmcl.2011.04.046] |
| 201. Vullo D, Nishimori I, Minakuchi T, Scozzafava A, Supuran CT.. (2011) Inhibition studies with anions and small molecules of two novel β-carbonic anhydrases from the bacterial pathogen Salmonella enterica serovar Typhimurium., 21 (12): [PMID:21570835] [10.1016/j.bmcl.2011.04.105] |
| 202. Hen N, Bialer M, Yagen B, Maresca A, Aggarwal M, Robbins AH, McKenna R, Scozzafava A, Supuran CT.. (2011) Anticonvulsant 4-aminobenzenesulfonamide derivatives with branched-alkylamide moieties: X-ray crystallography and inhibition studies of human carbonic anhydrase isoforms I, II, VII, and XIV., 54 (11): [PMID:21506569] [10.1021/jm200209n] |
| 203. Güzel O, Innocenti A, Scozzafava A, Salman A, Supuran CT.. (2009) Carbonic anhydrase inhibitors. Phenacetyl-, pyridylacetyl- and thienylacetyl-substituted aromatic sulfonamides act as potent and selective isoform VII inhibitors., 19 (12): [PMID:19435663] [10.1016/j.bmcl.2009.04.123] |
| 204. Xiao Z, Duan R, Cui W, Zhang Y, Zhang S, Chen F, Zhang Y, Liu J, Zhang D, Meng Y, Wang L, Wang H.. (2011) Synthesis and evaluation of new carbonic anhydrase inhibitors., 19 (10): [PMID:21524585] [10.1016/j.bmc.2011.03.061] |
| 205. Biswas S, Aggarwal M, Güzel Ö, Scozzafava A, McKenna R, Supuran CT.. (2011) Conformational variability of different sulfonamide inhibitors with thienyl-acetamido moieties attributes to differential binding in the active site of cytosolic human carbonic anhydrase isoforms., 19 (12): [PMID:21620713] [10.1016/j.bmc.2011.05.006] |
| 206. Rami M, Maresca A, Smaine FZ, Montero JL, Scozzafava A, Winum JY, Supuran CT.. (2011) Sulfonamides incorporating boroxazolidone moieties are potent inhibitors of the transmembrane, tumor-associated carbonic anhydrase isoforms IX and XII., 21 (10): [PMID:21470859] [10.1016/j.bmcl.2011.03.055] |
| 207. Oztürk Sarikaya SB, Topal F, Sentürk M, Gülçin I, Supuran CT.. (2011) In vitro inhibition of α-carbonic anhydrase isozymes by some phenolic compounds., 21 (14): [PMID:21669522] [10.1016/j.bmcl.2011.05.071] |
| 208. Nishimori I, Minakuchi T, Vullo D, Scozzafava A, Supuran CT.. (2011) Inhibition studies of the β-carbonic anhydrases from the bacterial pathogen Salmonella enterica serovar Typhimurium with sulfonamides and sulfamates., 19 (16): [PMID:21757360] [10.1016/j.bmc.2011.06.038] |
| 209. Carta F, Garaj V, Maresca A, Wagner J, Avvaru BS, Robbins AH, Scozzafava A, McKenna R, Supuran CT.. (2011) Sulfonamides incorporating 1,3,5-triazine moieties selectively and potently inhibit carbonic anhydrase transmembrane isoforms IX, XII and XIV over cytosolic isoforms I and II: Solution and X-ray crystallographic studies., 19 (10): [PMID:21515057] [10.1016/j.bmc.2011.04.005] |
| 210. al-Rashida M, Ashraf M, Hussain B, Nagra SA, Abbas G.. (2011) Discovery of new chromone containing sulfonamides as potent inhibitors of bovine cytosolic carbonic anhydrase., 19 (11): [PMID:21555223] [10.1016/j.bmc.2011.04.040] |
| 211. Brzozowski Z, Sławiński J, Gdaniec M, Innocenti A, Supuran CT.. (2011) Carbonic anhydrase inhibitors. Synthesis, molecular structures, and inhibition of the human cytosolic isozymes I and II and transmembrane isozymes IX, XII (cancer-associated) and XIV with novel 3-pyridinesulfonamide derivatives., 46 (9): [PMID:21820216] [10.1016/j.ejmech.2011.07.011] |
| 212. Rami M, Innocenti A, Montero JL, Scozzafava A, Winum JY, Supuran CT.. (2011) Synthesis of rhodamine B-benzenesulfonamide conjugates and their inhibitory activity against human α- and bacterial/fungal β-carbonic anhydrases., 21 (18): [PMID:21821413] [10.1016/j.bmcl.2011.07.045] |
| 213. Salmon AJ, Williams ML, Maresca A, Supuran CT, Poulsen SA.. (2011) Synthesis of glycoconjugate carbonic anhydrase inhibitors by ruthenium-catalysed azide-alkyne 1,3-dipolar cycloaddition., 21 (20): [PMID:21903393] [10.1016/j.bmcl.2011.08.066] |
| 214. Knaus EE, Innocenti A, Scozzafava A, Supuran CT.. (2011) Phenylethynylbenzenesulfonamide regioisomers strongly and selectively inhibit the transmembrane, tumor-associated carbonic anhydrase isoforms IX and XII over the cytosolic isoforms I and II., 21 (19): [PMID:21852133] [10.1016/j.bmcl.2011.07.090] |
| 215. Morris JC, Chiche J, Grellier C, Lopez M, Bornaghi LF, Maresca A, Supuran CT, Pouysségur J, Poulsen SA.. (2011) Targeting hypoxic tumor cell viability with carbohydrate-based carbonic anhydrase IX and XII inhibitors., 54 (19): [PMID:21851094] [10.1021/jm200892s] |
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| 217. PubChem BioAssay data set, |
| 218. Scott S. Auerbach, DrugMatrix¨ and ToxFX¨ Coordinator National Toxicology Program. DrugMatrix in vitro pharmacology data, |
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| 220. Ohradanova A, Vullo D, Pastorekova S, Pastorek J, Jackson DJ, Wörheide G, Supuran CT.. (2012) Cloning, characterization and sulfonamide inhibition studies of an α-carbonic anhydrase from the living fossil sponge Astrosclera willeyana., 20 (4): [PMID:22285172] [10.1016/j.bmc.2012.01.007] |
| 221. Balaydın HT, Sentürk M, Menzek A.. (2012) Synthesis and carbonic anhydrase inhibitory properties of novel cyclohexanonyl bromophenol derivatives., 22 (3): [PMID:22230050] [10.1016/j.bmcl.2011.12.069] |
| 222. Ekinci D, Cavdar H, Durdagi S, Talaz O, Sentürk M, Supuran CT.. (2012) Structure-activity relationships for the interaction of 5,10-dihydroindeno[1,2-b]indole derivatives with human and bovine carbonic anhydrase isoforms I, II, III, IV and VI., 49 [PMID:22245047] [10.1016/j.ejmech.2011.12.022] |
| 223. Truppo E, Supuran CT, Sandomenico A, Vullo D, Innocenti A, Di Fiore A, Alterio V, De Simone G, Monti SM.. (2012) Carbonic anhydrase VII is S-glutathionylated without loss of catalytic activity and affinity for sulfonamide inhibitors., 22 (4): [PMID:22277279] [10.1016/j.bmcl.2011.12.134] |
| 224. Ohradanova A, Vullo D, Pastorekova S, Pastorek J, Jackson DJ, Wörheide G, Supuran CT.. (2012) Anion inhibition studies of an α-carbonic anhydrase from the living fossil Astrosclera willeyana., 22 (3): [PMID:22227210] [10.1016/j.bmcl.2011.12.085] |
| 225. Moeker J, Teruya K, Rossit S, Wilkinson BL, Lopez M, Bornaghi LF, Innocenti A, Supuran CT, Poulsen SA.. (2012) Design and synthesis of thiourea compounds that inhibit transmembrane anchored carbonic anhydrases., 20 (7): [PMID:22370338] [10.1016/j.bmc.2012.01.052] |
| 226. Turkoglu S, Maresca A, Alper M, Kockar F, Işık S, Sinan S, Ozensoy O, Arslan O, Supuran CT.. (2012) Mutation of active site residues Asn67 to Ile, Gln92 to Val and Leu204 to Ser in human carbonic anhydrase II: influences on the catalytic activity and affinity for inhibitors., 20 (7): [PMID:22386980] [10.1016/j.bmc.2012.02.029] |
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| 228. Carta F, Aggarwal M, Maresca A, Scozzafava A, McKenna R, Masini E, Supuran CT.. (2012) Dithiocarbamates strongly inhibit carbonic anhydrases and show antiglaucoma action in vivo., 55 (4): [PMID:22276570] [10.1021/jm300031j] |
| 229. Balaydın HT, Şentürk M, Göksu S, Menzek A.. (2012) Synthesis and carbonic anhydrase inhibitory properties of novel bromophenols and their derivatives including natural products: vidalol B., 54 [PMID:22687439] [10.1016/j.ejmech.2012.05.025] |
| 230. Hewitson KS, Vullo D, Scozzafava A, Mastrolorenzo A, Supuran CT.. (2012) Molecular cloning, characterization, and inhibition studies of a β-carbonic anhydrase from Malassezia globosa, a potential antidandruff target., 55 (7): [PMID:22424239] [10.1021/jm300203r] |
| 231. Gitto R, Damiano FM, Mader P, De Luca L, Ferro S, Supuran CT, Vullo D, Brynda J, Rezáčová P, Chimirri A.. (2012) Synthesis, structure-activity relationship studies, and X-ray crystallographic analysis of arylsulfonamides as potent carbonic anhydrase inhibitors., 55 (8): [PMID:22443141] [10.1021/jm300112w] |
| 232. De Luca V, Vullo D, Scozzafava A, Carginale V, Rossi M, Supuran CT, Capasso C.. (2012) Anion inhibition studies of an α-carbonic anhydrase from the thermophilic bacterium Sulfurihydrogenibium yellowstonense YO3AOP1., 22 (17): [PMID:22835873] [10.1016/j.bmcl.2012.06.106] |
| 233. Sechi M, Innocenti A, Pala N, Rogolino D, Carcelli M, Scozzafava A, Supuran CT.. (2012) Inhibition of α-class cytosolic human carbonic anhydrases I, II, IX and XII, and β-class fungal enzymes by carboxylic acids and their derivatives: new isoform-I selective nanomolar inhibitors., 22 (18): [PMID:22901388] [10.1016/j.bmcl.2012.07.094] |
| 234. Uwai Y, Saito H, Hashimoto Y, Inui KI.. (2000) Interaction and transport of thiazide diuretics, loop diuretics, and acetazolamide via rat renal organic anion transporter rOAT1., 295 (1): [PMID:10991988] |
| 235. USP Dictionary of USAN and International Names (2010 edition) and USAN registrations 2007-date, |
| 236. D'Ambrosio K, Smaine FZ, Carta F, De Simone G, Winum JY, Supuran CT.. (2012) Development of potent carbonic anhydrase inhibitors incorporating both sulfonamide and sulfamide groups., 55 (15): [PMID:22775345] [10.1021/jm300818k] |
| 237. Deprez-Poulain R, Flipo M, Piveteau C, Leroux F, Dassonneville S, Florent I, Maes L, Cos P, Deprez B.. (2012) Structure-activity relationships and blood distribution of antiplasmodial aminopeptidase-1 inhibitors., 55 (24): [PMID:23176597] [10.1021/jm301506h] |
| 238. Del Prete S, Isik S, Vullo D, De Luca V, Carginale V, Scozzafava A, Supuran CT, Capasso C.. (2012) DNA cloning, characterization, and inhibition studies of an α-carbonic anhydrase from the pathogenic bacterium Vibrio cholerae., 55 (23): [PMID:23181552] [10.1021/jm301611m] |
| 239. Brzozowski Z, Sławiński J, Vullo D, Supuran CT.. (2012) Carbonic anhydrase inhibitors. Regioselective synthesis of novel series 1-substituted 1,4-dihydro-4-oxo-3-pyridinesulfonamides and their inhibition of the human cytosolic isozymes I and II and transmembrane cancer-associated isozymes IX and XII., 56 [PMID:22910138] [10.1016/j.ejmech.2012.08.006] |
| 240. Vullo D, De Luca V, Scozzafava A, Carginale V, Rossi M, Supuran CT, Capasso C.. (2012) Anion inhibition studies of the fastest carbonic anhydrase (CA) known, the extremo-CA from the bacterium Sulfurihydrogenibium azorense., 22 (23): [PMID:23072866] [10.1016/j.bmcl.2012.09.065] |
| 241. Nishimori I, Vullo D, Minakuchi T, Scozzafava A, Capasso C, Supuran CT.. (2013) Restoring catalytic activity to the human carbonic anhydrase (CA) related proteins VIII, X and XI affords isoforms with high catalytic efficiency and susceptibility to anion inhibition., 23 (1): [PMID:23200251] [10.1016/j.bmcl.2012.10.103] |
| 242. Bozdag M, Dreker T, Henry C, Tosco P, Vallaro M, Fruttero R, Scozzafava A, Carta F, Supuran CT.. (2013) Novel small molecule protein arginine deiminase 4 (PAD4) inhibitors., 23 (3): [PMID:23265898] [10.1016/j.bmcl.2012.11.102] |
| 243. Pan P, Vermelho AB, Capaci Rodrigues G, Scozzafava A, Tolvanen ME, Parkkila S, Capasso C, Supuran CT.. (2013) Cloning, characterization, and sulfonamide and thiol inhibition studies of an α-carbonic anhydrase from Trypanosoma cruzi, the causative agent of Chagas disease., 56 (4): [PMID:23391336] [10.1021/jm4000616] |
| 244. Long DD, Frieman B, Hegde SS, Hill CM, Jiang L, Kintz S, Marquess DG, Purkey H, Shaw JP, Steinfeld T, Wilson MS, Wrench K.. (2013) A multivalent approach towards linked dual-pharmacology prostaglandin F receptor agonist/carbonic anhydrase-II inhibitors for the treatment of glaucoma., 23 (4): [PMID:23317571] [10.1016/j.bmcl.2012.12.058] |
| 245. Tars K, Vullo D, Kazaks A, Leitans J, Lends A, Grandane A, Zalubovskis R, Scozzafava A, Supuran CT.. (2013) Sulfocoumarins (1,2-benzoxathiine-2,2-dioxides): a class of potent and isoform-selective inhibitors of tumor-associated carbonic anhydrases., 56 (1): [PMID:23241068] [10.1021/jm301625s] |
| 246. Güzel-Akdemir Ö, Akdemir A, Isik S, Vullo D, Supuran CT.. (2013) o-Benzenedisulfonimido-sulfonamides are potent inhibitors of the tumor-associated carbonic anhydrase isoforms CA IX and CA XII., 21 (6): [PMID:23352754] [10.1016/j.bmc.2012.12.037] |
| 247. Dudutienė V, Zubrienė A, Smirnov A, Gylytė J, Timm D, Manakova E, Gražulis S, Matulis D.. (2013) 4-Substituted-2,3,5,6-tetrafluorobenzenesulfonamides as inhibitors of carbonic anhydrases I, II, VII, XII, and XIII., 21 (7): [PMID:23394791] [10.1016/j.bmc.2013.01.008] |
| 248. Akıncıoğlu A, Akbaba Y, Göçer H, Göksu S, Gülçin İ, Supuran CT.. (2013) Novel sulfamides as potential carbonic anhydrase isoenzymes inhibitors., 21 (6): [PMID:23394864] [10.1016/j.bmc.2013.01.019] |
| 249. Syrjänen L, Tolvanen ME, Hilvo M, Vullo D, Carta F, Supuran CT, Parkkila S.. (2013) Characterization, bioinformatic analysis and dithiocarbamate inhibition studies of two new α-carbonic anhydrases, CAH1 and CAH2, from the fruit fly Drosophila melanogaster., 21 (6): [PMID:22989910] [10.1016/j.bmc.2012.08.046] |
| 250. Luca VD, Vullo D, Scozzafava A, Carginale V, Rossi M, Supuran CT, Capasso C.. (2013) An α-carbonic anhydrase from the thermophilic bacterium Sulphurihydrogenibium azorense is the fastest enzyme known for the CO2 hydration reaction., 21 (6): [PMID:23078755] [10.1016/j.bmc.2012.09.047] |
| 251. Jogaitė V, Zubrienė A, Michailovienė V, Gylytė J, Morkūnaitė V, Matulis D.. (2013) Characterization of human carbonic anhydrase XII stability and inhibitor binding., 21 (6): [PMID:23159038] [10.1016/j.bmc.2012.10.016] |
| 252. Rogez-Florent T, Meignan S, Foulon C, Six P, Gros A, Bal-Mahieu C, Supuran CT, Scozzafava A, Frédérick R, Masereel B, Depreux P, Lansiaux A, Goossens JF, Gluszok S, Goossens L.. (2013) New selective carbonic anhydrase IX inhibitors: synthesis and pharmacological evaluation of diarylpyrazole-benzenesulfonamides., 21 (6): [PMID:23168081] [10.1016/j.bmc.2012.10.029] |
| 253. Gao R, Liao S, Zhang C, Zhu W, Wang L, Huang J, Zhao Z, Li H, Qian X, Xu Y.. (2013) Optimization of heterocyclic substituted benzenesulfonamides as novel carbonic anhydrase IX inhibitors and their structure activity relationship., 62 [PMID:23429054] [10.1016/j.ejmech.2013.01.030] |
| 254. Alafeefy AM, Isik S, Abdel-Aziz HA, Ashour AE, Vullo D, Al-Jaber NA, Supuran CT.. (2013) Carbonic anhydrase inhibitors: benzenesulfonamides incorporating cyanoacrylamide moieties are low nanomolar/subnanomolar inhibitors of the tumor-associated isoforms IX and XII., 21 (6): [PMID:23290254] [10.1016/j.bmc.2012.12.004] |
| 255. Monti SM, De Simone G, Dathan NA, Ludwig M, Vullo D, Scozzafava A, Capasso C, Supuran CT.. (2013) Kinetic and anion inhibition studies of a β-carbonic anhydrase (FbiCA 1) from the C4 plant Flaveria bidentis., 23 (6): [PMID:23414801] [10.1016/j.bmcl.2013.01.087] |
| 256. Biswas S, Carta F, Scozzafava A, McKenna R, Supuran CT.. (2013) Structural effect of phenyl ring compared to thiadiazole based adamantyl-sulfonamides on carbonic anhydrase inhibition., 21 (8): [PMID:23490152] [10.1016/j.bmc.2013.02.022] |
| 257. Vullo D, Luca VD, Scozzafava A, Carginale V, Rossi M, Supuran CT, Capasso C.. (2013) The alpha-carbonic anhydrase from the thermophilic bacterium Sulfurihydrogenibium yellowstonense YO3AOP1 is highly susceptible to inhibition by sulfonamides., 21 (6): [PMID:22883029] [10.1016/j.bmc.2012.07.024] |
| 258. Vullo D, Leewattanapasuk W, Mühlschlegel FA, Mastrolorenzo A, Capasso C, Supuran CT.. (2013) Carbonic anhydrase inhibitors: inhibition of the β-class enzyme from the pathogenic yeast Candida glabrata with sulfonamides, sulfamates and sulfamides., 23 (9): [PMID:23511020] [10.1016/j.bmcl.2013.02.092] |
| 259. Carta F, Akdemir A, Scozzafava A, Masini E, Supuran CT.. (2013) Xanthates and trithiocarbonates strongly inhibit carbonic anhydrases and show antiglaucoma effects in vivo., 56 (11): [PMID:23647428] [10.1021/jm400414j] |
| 260. Aksu K, Nar M, Tanc M, Vullo D, Gülçin I, Göksu S, Tümer F, Supuran CT.. (2013) Synthesis and carbonic anhydrase inhibitory properties of sulfamides structurally related to dopamine., 21 (11): [PMID:23623256] [10.1016/j.bmc.2013.03.077] |
| 261. Alafeefy AM, Isik S, Al-Jaber NA, Vullo D, Abdel-Aziz HA, Ashour AE, Awaad AS, Capasso C, Supuran CT.. (2013) Carbonic anhydrase inhibitors. Benzenesulfonamides incorporating cyanoacrylamide moieties strongly inhibit Saccharomyces cerevisiae β-carbonic anhydrase., 23 (12): [PMID:23642478] [10.1016/j.bmcl.2013.04.028] |
| 262. Wang L, Yang C, Lu W, Liu L, Gao R, Liao S, Zhao Z, Zhu L, Xu Y, Li H, Huang J, Zhu W.. (2013) Discovery of new potent inhibitors for carbonic anhydrase IX by structure-based virtual screening., 23 (12): [PMID:23664215] [10.1016/j.bmcl.2013.04.048] |
| 263. Güzel-Akdemir Ö, Akdemir A, Pan P, Vermelho AB, Parkkila S, Scozzafava A, Capasso C, Supuran CT.. (2013) A class of sulfonamides with strong inhibitory action against the α-carbonic anhydrase from Trypanosoma cruzi., 56 (14): [PMID:23815159] [10.1021/jm400418p] |
| 264. Said HM, Hagemann C, Carta F, Katzer A, Polat B, Staab A, Scozzafava A, Anacker J, Vince GH, Flentje M, Supuran CT.. (2013) Hypoxia induced CA9 inhibitory targeting by two different sulfonamide derivatives including acetazolamide in human glioblastoma., 21 (13): [PMID:23706268] [10.1016/j.bmc.2013.03.068] |
| 265. Del Prete S, Vullo D, De Luca V, Carginale V, Scozzafava A, Supuran CT, Capasso C.. (2013) A highly catalytically active γ-carbonic anhydrase from the pathogenic anaerobe Porphyromonas gingivalis and its inhibition profile with anions and small molecules., 23 (14): [PMID:23769640] [10.1016/j.bmcl.2013.05.063] |
| 266. Tanc M, Carta F, Bozdag M, Scozzafava A, Supuran CT.. (2013) 7-Substituted-sulfocoumarins are isoform-selective, potent carbonic anhydrase II inhibitors., 21 (15): [PMID:23769167] [10.1016/j.bmc.2013.05.032] |
| 267. Suthar SK, Bansal S, Lohan S, Modak V, Chaudhary A, Tiwari A.. (2013) Design and synthesis of novel 4-(4-oxo-2-arylthiazolidin-3-yl)benzenesulfonamides as selective inhibitors of carbonic anhydrase IX over I and II with potential anticancer activity., 66 [PMID:23827177] [10.1016/j.ejmech.2013.06.003] |
| 268. Wang ZC, Qin YJ, Wang PF, Yang YA, Wen Q, Zhang X, Qiu HY, Duan YT, Wang YT, Sang YL, Zhu HL.. (2013) Sulfonamides containing coumarin moieties selectively and potently inhibit carbonic anhydrases II and IX: design, synthesis, inhibitory activity and 3D-QSAR analysis., 66 [PMID:23777898] [10.1016/j.ejmech.2013.04.035] |
| 269. Akdemir A, Güzel-Akdemir O, Scozzafava A, Capasso C, Supuran CT.. (2013) Inhibition of tumor-associated human carbonic anhydrase isozymes IX and XII by a new class of substituted-phenylacetamido aromatic sulfonamides., 21 (17): [PMID:23842519] [10.1016/j.bmc.2013.06.029] |
| 270. Leitans J, Sprudza A, Tanc M, Vozny I, Zalubovskis R, Tars K, Supuran CT.. (2013) 5-Substituted-(1,2,3-triazol-4-yl)thiophene-2-sulfonamides strongly inhibit human carbonic anhydrases I, II, IX and XII: solution and X-ray crystallographic studies., 21 (17): [PMID:23859774] [10.1016/j.bmc.2013.06.041] |
| 271. Sethi KK, Verma SM, Tanç M, Carta F, Supuran CT.. (2013) Carbonic anhydrase inhibitors: Synthesis and inhibition of the cytosolic mammalian carbonic anhydrase isoforms I, II and VII with benzene sulfonamides incorporating 4,5,6,7-tetrachlorophthalimide moiety., 21 (17): [PMID:23867389] [10.1016/j.bmc.2013.06.035] |
| 272. Ulus R, Yeşildağ I, Tanç M, Bülbül M, Kaya M, Supuran CT.. (2013) Synthesis of novel acridine and bis acridine sulfonamides with effective inhibitory activity against the cytosolic carbonic anhydrase isoforms II and VII., 21 (18): [PMID:23910989] [10.1016/j.bmc.2013.07.014] |
| 273. Sethi KK, Vullo D, Verma SM, Tanç M, Carta F, Supuran CT.. (2013) Carbonic anhydrase inhibitors: synthesis and inhibition of the human carbonic anhydrase isoforms I, II, VII, IX and XII with benzene sulfonamides incorporating 4,5,6,7-tetrabromophthalimide moiety., 21 (19): [PMID:23965175] [10.1016/j.bmc.2013.07.044] |
| 274. Biswas S, McKenna R, Supuran CT.. (2013) Effect of incorporating a thiophene tail in the scaffold of acetazolamide on the inhibition of human carbonic anhydrase isoforms I, II, IX and XII., 23 (20): [PMID:23993330] [10.1016/j.bmcl.2013.08.019] |
| 275. Day JA, Cohen SM.. (2013) Investigating the selectivity of metalloenzyme inhibitors., 56 (20): [PMID:24074025] [10.1021/jm401053m] |
| 276. Syrjänen L, Vermelho AB, Rodrigues Ide A, Corte-Real S, Salonen T, Pan P, Vullo D, Parkkila S, Capasso C, Supuran CT.. (2013) Cloning, characterization, and inhibition studies of a β-carbonic anhydrase from Leishmania donovani chagasi, the protozoan parasite responsible for leishmaniasis., 56 (18): [PMID:23977960] [10.1021/jm400939k] |
| 277. Pinard MA, Boone CD, Rife BD, Supuran CT, McKenna R.. (2013) Structural study of interaction between brinzolamide and dorzolamide inhibition of human carbonic anhydrases., 21 (22): [PMID:24090602] [10.1016/j.bmc.2013.08.033] |
| 278. Čapkauskaitė E, Zubrienė A, Smirnov A, Torresan J, Kišonaitė M, Kazokaitė J, Gylytė J, Michailovienė V, Jogaitė V, Manakova E, Gražulis S, Tumkevičius S, Matulis D.. (2013) Benzenesulfonamides with pyrimidine moiety as inhibitors of human carbonic anhydrases I, II, VI, VII, XII, and XIII., 21 (22): [PMID:24103428] [10.1016/j.bmc.2013.09.029] |
| 279. Ceruso M, Vullo D, Scozzafava A, Supuran CT.. (2013) Inhibition of human carbonic anhydrase isoforms I-XIV with sulfonamides incorporating fluorine and 1,3,5-triazine moieties., 21 (22): [PMID:24103430] [10.1016/j.bmc.2013.09.031] |
| 280. Unpublished dataset, |
| 281. Unpublished dataset, |
| 282. Unpublished dataset, |
| 283. De Bruyn T, van Westen GJ, Ijzerman AP, Stieger B, de Witte P, Augustijns PF, Annaert PP.. (2013) Structure-based identification of OATP1B1/3 inhibitors., 83 (6): [PMID:23571415] [10.1124/mol.112.084152] |
| 284. Rami M, Dubois L, Parvathaneni NK, Alterio V, van Kuijk SJ, Monti SM, Lambin P, De Simone G, Supuran CT, Winum JY.. (2013) Hypoxia-targeting carbonic anhydrase IX inhibitors by a new series of nitroimidazole-sulfonamides/sulfamides/sulfamates., 56 (21): [PMID:24128000] [10.1021/jm4009532] |
| 285. Carradori S, De Monte C, D'Ascenzio M, Secci D, Celik G, Ceruso M, Vullo D, Scozzafava A, Supuran CT.. (2013) Salen and tetrahydrosalen derivatives act as effective inhibitors of the tumor-associated carbonic anhydrase XII--a new scaffold for designing isoform-selective inhibitors., 23 (24): [PMID:24189056] [10.1016/j.bmcl.2013.10.026] |
| 286. Carroux CJ, Rankin GM, Moeker J, Bornaghi LF, Katneni K, Morizzi J, Charman SA, Vullo D, Supuran CT, Poulsen SA.. (2013) A prodrug approach toward cancer-related carbonic anhydrase inhibition., 56 (23): [PMID:24200125] [10.1021/jm401163e] |
| 287. McComsey DF, Smith-Swintosky VL, Parker MH, Brenneman DE, Malatynska E, White HS, Klein BD, Wilcox KS, Milewski ME, Herb M, Finley MF, Liu Y, Lubin ML, Qin N, Reitz AB, Maryanoff BE.. (2013) Novel, broad-spectrum anticonvulsants containing a sulfamide group: pharmacological properties of (S)-N-[(6-chloro-2,3-dihydrobenzo[1,4]dioxin-2-yl)methyl]sulfamide (JNJ-26489112)., 56 (22): [PMID:24205976] [10.1021/jm400894u] |
| 288. Vullo D, Sai Kumar RS, Scozzafava A, Capasso C, Ferry JG, Supuran CT.. (2013) Anion inhibition studies of a β-carbonic anhydrase from Clostridium perfringens., 23 (24): [PMID:24210500] [10.1016/j.bmcl.2013.10.037] |
| 289. Alafeefy AM, Abdel-Aziz HA, Vullo D, Al-Tamimi AM, Al-Jaber NA, Capasso C, Supuran CT.. (2014) Inhibition of carbonic anhydrases from the extremophilic bacteria Sulfurihydrogenibium yellostonense (SspCA) and S. azorense (SazCA) with a new series of sulfonamides incorporating aroylhydrazone-, [1,2,4]triazolo[3,4-b][1,3,4]thiadiazinyl- or 2-(cyanophenylmethylene)-1,3,4-thiadiazol-3(2H)-yl moieties., 22 (1): [PMID:24332658] [10.1016/j.bmc.2013.11.042] |
| 290. De Luca L, Ferro S, Damiano FM, Supuran CT, Vullo D, Chimirri A, Gitto R.. (2014) Structure-based screening for the discovery of new carbonic anhydrase VII inhibitors., 71 [PMID:24287559] [10.1016/j.ejmech.2013.10.071] |
| 291. Bozdag M, Ferraroni M, Nuti E, Vullo D, Rossello A, Carta F, Scozzafava A, Supuran CT.. (2014) Combining the tail and the ring approaches for obtaining potent and isoform-selective carbonic anhydrase inhibitors: solution and X-ray crystallographic studies., 22 (1): [PMID:24300919] [10.1016/j.bmc.2013.11.016] |
| 292. Vullo D, Del Prete S, Osman SM, De Luca V, Scozzafava A, Alothman Z, Supuran CT, Capasso C.. (2014) Sulfonamide inhibition studies of the δ-carbonic anhydrase from the diatom Thalassiosira weissflogii., 24 (1): [PMID:24314394] [10.1016/j.bmcl.2013.11.021] |
| 293. Vullo D, Del Prete S, Osman SM, De Luca V, Scozzafava A, Alothman Z, Supuran CT, Capasso C.. (2014) Sulfonamide inhibition studies of the γ-carbonic anhydrase from the oral pathogen Porphyromonas gingivalis., 24 (1): [PMID:24316122] [10.1016/j.bmcl.2013.11.030] |
| 294. Żołnowska B, Sławiński J, Pogorzelska A, Chojnacki J, Vullo D, Supuran CT.. (2014) Carbonic anhydrase inhibitors. Synthesis, and molecular structure of novel series N-substituted N'-(2-arylmethylthio-4-chloro-5-methylbenzenesulfonyl)guanidines and their inhibition of human cytosolic isozymes I and II and the transmembrane tumor-associated isozymes IX and XII., 71 [PMID:24291567] [10.1016/j.ejmech.2013.10.081] |
| 295. Sethi KK, Verma SM, Tanç M, Purper G, Calafato G, Carta F, Supuran CT.. (2014) Carbonic anhydrase inhibitors: synthesis and inhibition of the human carbonic anhydrase isoforms I, II, IX and XII with benzene sulfonamides incorporating 4- and 3-nitrophthalimide moieties., 22 (5): [PMID:24513184] [10.1016/j.bmc.2014.01.031] |
| 296. Grandane A, Tanc M, Zalubovskis R, Supuran CT.. (2014) Synthesis of 6-tetrazolyl-substituted sulfocoumarins acting as highly potent and selective inhibitors of the tumor-associated carbonic anhydrase isoforms IX and XII., 22 (5): [PMID:24513186] [10.1016/j.bmc.2014.01.043] |
| 297. Nishimori I, Vullo D, Minakuchi T, Scozzafava A, Osman SM, AlOthman Z, Capasso C, Supuran CT.. (2014) Anion inhibition studies of two new β-carbonic anhydrases from the bacterial pathogen Legionella pneumophila., 24 (4): [PMID:24461298] [10.1016/j.bmcl.2013.12.124] |
| 298. Saluja AK, Tiwari M, Vullo D, Supuran CT.. (2014) Substituted benzene sulfonamides incorporating 1,3,5-triazinyl moieties potently inhibit human carbonic anhydrases II, IX and XII., 24 (5): [PMID:24507918] [10.1016/j.bmcl.2014.01.048] |
| 299. SitaRam, Celik G, Khloya P, Vullo D, Supuran CT, Sharma PK.. (2014) Benzenesulfonamide bearing 1,2,4-triazole scaffolds as potent inhibitors of tumor associated carbonic anhydrase isoforms hCA IX and hCA XII., 22 (6): [PMID:24560737] [10.1016/j.bmc.2014.01.055] |
| 300. D'Ascenzio M, Carradori S, De Monte C, Secci D, Ceruso M, Supuran CT.. (2014) Design, synthesis and evaluation of N-substituted saccharin derivatives as selective inhibitors of tumor-associated carbonic anhydrase XII., 22 (6): [PMID:24560739] [10.1016/j.bmc.2014.01.056] |
| 301. Khloya P, Celik G, SitaRam, Vullo D, Supuran CT, Sharma PK.. (2014) 4-Functionalized 1,3-diarylpyrazoles bearing benzenesulfonamide moiety as selective potent inhibitors of the tumor associated carbonic anhydrase isoforms IX and XII., 76 [PMID:24589484] [10.1016/j.ejmech.2014.02.023] |
| 302. Grandane A, Tanc M, Zalubovskis R, Supuran CT.. (2014) 6-Triazolyl-substituted sulfocoumarins are potent, selective inhibitors of the tumor-associated carbonic anhydrases IX and XII., 24 (5): [PMID:24518190] [10.1016/j.bmcl.2014.01.076] |
| 303. Biour M, Ben Salem C, Chazouillères O, Grangé JD, Serfaty L, Poupon R.. (2004) [Drug-induced liver injury; fourteenth updated edition of the bibliographic database of liver injuries and related drugs]., 28 (8-9): [PMID:15646539] [10.1016/s0399-8320(04)95062-2] |
| 304. PubChem BioAssay data set, |
| 305. PubChem BioAssay data set, |
| 306. PubChem BioAssay data set, |
| 307. Congiu C, Onnis V, Balboni G, Supuran CT.. (2014) Synthesis and carbonic anhydrase I, II, IX and XII inhibition studies of 4-N,N-disubstituted sulfanilamides incorporating 4,4,4-trifluoro-3-oxo-but-1-enyl, phenacylthiourea and imidazol-2(3H)-one/thione moieties., 24 (7): [PMID:24589511] [10.1016/j.bmcl.2014.02.030] |
| 308. Zaib S, Saeed A, Stolte K, Flörke U, Shahid M, Iqbal J.. (2014) New aminobenzenesulfonamide-thiourea conjugates: synthesis and carbonic anhydrase inhibition and docking studies., 78 [PMID:24681391] [10.1016/j.ejmech.2014.03.023] |
| 309. Tauro M, Loiodice F, Ceruso M, Supuran CT, Tortorella P.. (2014) Arylamino bisphosphonates: potent and selective inhibitors of the tumor-associated carbonic anhydrase XII., 24 (8): [PMID:24650641] [10.1016/j.bmcl.2014.03.001] |
| 310. Cross PE, Gadsby B.. (1978) Cerebrovasodilatation through selective inhibition of the enzyme carbonic anhydrase. 1. Substituted benzenedisulfonamides., 21 (9): [PMID:722750] [10.1021/jm00207a001] |
| 311. Nishimori I, Vullo D, Minakuchi T, Scozzafava A, Capasso C, Supuran CT.. (2014) Sulfonamide inhibition studies of two β-carbonic anhydrases from the bacterial pathogen Legionella pneumophila., 22 (11): [PMID:24792813] [10.1016/j.bmc.2014.04.006] |
| 312. Mojzych M, Bielawska A, Bielawski K, Ceruso M, Supuran CT.. (2014) Pyrazolo[4,3-e][1,2,4]triazine sulfonamides as carbonic anhydrase inhibitors with antitumor activity., 22 (9): [PMID:24713308] [10.1016/j.bmc.2014.03.029] |
| 313. Nasr G, Cristian A, Barboiu M, Vullo D, Winum JY, Supuran CT.. (2014) Carbonic anhydrase inhibitors. Inhibition of human cytosolic isoforms I and II with (reduced) Schiff's bases incorporating sulfonamide, carboxylate and carboxymethyl moieties., 22 (10): [PMID:24746465] [10.1016/j.bmc.2014.03.041] |
| 314. Tauro M, Loiodice F, Ceruso M, Supuran CT, Tortorella P.. (2014) Dual carbonic anhydrase/matrix metalloproteinase inhibitors incorporating bisphosphonic acid moieties targeting bone tumors., 24 (12): [PMID:24813742] [10.1016/j.bmcl.2014.04.077] |
| 315. Sławiński J, Pogorzelska A, Żołnowska B, Brożewicz K, Vullo D, Supuran CT.. (2014) Carbonic anhydrase inhibitors. Synthesis of a novel series of 5-substituted 2,4-dichlorobenzenesulfonamides and their inhibition of human cytosolic isozymes I and II and the transmembrane tumor-associated isozymes IX and XII., 82 [PMID:24871996] [10.1016/j.ejmech.2014.05.039] |
| 316. Ghorab MM, Alsaid MS, Ceruso M, Nissan YM, Supuran CT.. (2014) Carbonic anhydrase inhibitors: Synthesis, molecular docking, cytotoxic and inhibition of the human carbonic anhydrase isoforms I, II, IX, XII with novel benzenesulfonamides incorporating pyrrole, pyrrolopyrimidine and fused pyrrolopyrimidine moieties., 22 (14): [PMID:24878360] [10.1016/j.bmc.2014.05.009] |
| 317. Mark Wenlock and Nicholas Tomkinson. Experimental in vitro DMPK and physicochemical data on a set of publicly disclosed compounds, [10.6019/CHEMBL3301361] |
| 318. Prete SD, Vullo D, Osman SM, Scozzafava A, AlOthman Z, Capasso C, Supuran CT.. (2014) Sulfonamide inhibition study of the carbonic anhydrases from the bacterial pathogen Porphyromonas gingivalis: the β-class (PgiCAb) versus the γ-class (PgiCA) enzymes., 22 (17): [PMID:25129169] [10.1016/j.bmc.2014.07.048] |
| 319. Bozdag M, Ferraroni M, Carta F, Vullo D, Lucarini L, Orlandini E, Rossello A, Nuti E, Scozzafava A, Masini E, Supuran CT.. (2014) Structural insights on carbonic anhydrase inhibitory action, isoform selectivity, and potency of sulfonamides and coumarins incorporating arylsulfonylureido groups., 57 (21): [PMID:25310626] [10.1021/jm501314c] |
| 320. Ombouma J, Vullo D, Supuran CT, Winum JY.. (2014) Ferrier sulfamidoglycosylation of glycals catalyzed by nitrosonium tetrafluoroborate: towards new carbonic anhydrase glycoinhibitors., 22 (22): [PMID:25438758] [10.1016/j.bmc.2014.09.053] |
| 321. De Monte C, Carradori S, Secci D, D'Ascenzio M, Vullo D, Ceruso M, Supuran CT.. (2014) Cyclic tertiary sulfamates: selective inhibition of the tumor-associated carbonic anhydrases IX and XII by N- and O-substituted acesulfame derivatives., 84 [PMID:25019479] [10.1016/j.ejmech.2014.07.014] |
| 322. Ghorab MM, Ceruso M, Alsaid MS, Nissan YM, Arafa RK, Supuran CT.. (2014) Novel sulfonamides bearing pyrrole and pyrrolopyrimidine moieties as carbonic anhydrase inhibitors: Synthesis, cytotoxic activity and molecular modeling., 87 [PMID:25255434] [10.1016/j.ejmech.2014.09.059] |
| 323. Pichake J, Kharkar PS, Ceruso M, Supuran CT, Toraskar MP.. (2014) Carbonic anhydrase inhibitors: design, synthesis, and biological evaluation of novel sulfonyl semicarbazide derivatives., 5 (7): [PMID:25050167] [10.1021/ml500140t] |
| 324. Alafeefy AM, Ceruso M, Al-Tamimi AM, Del Prete S, Capasso C, Supuran CT.. (2014) Quinazoline-sulfonamides with potent inhibitory activity against the α-carbonic anhydrase from Vibrio cholerae., 22 (19): [PMID:25194929] [10.1016/j.bmc.2014.08.015] |
| 325. SitaRam, Ceruso M, Khloya P, Supuran CT, Sharma PK.. (2014) 4-Functionalized 1,3-diarylpyrazoles bearing 6-aminosulfonylbenzothiazole moiety as potent inhibitors of carbonic anhydrase isoforms hCA I, II, IX and XII., 22 (24): [PMID:25456084] [10.1016/j.bmc.2014.10.018] |
| 326. Ceruso M, Del Prete S, Alothman Z, Capasso C, Supuran CT.. (2014) Sulfonamides with Potent Inhibitory Action and Selectivity against the α-Carbonic Anhydrase from Vibrio cholerae., 5 (7): [PMID:25050173] [10.1021/ml500192a] |
| 327. D'Ascenzio M, Carradori S, Secci D, Vullo D, Ceruso M, Akdemir A, Supuran CT.. (2014) Selective inhibition of human carbonic anhydrases by novel amide derivatives of probenecid: synthesis, biological evaluation and molecular modelling studies., 22 (15): [PMID:25027802] [10.1016/j.bmc.2014.06.003] |
| 328. Del Prete S, Vullo D, Fisher GM, Andrews KT, Poulsen SA, Capasso C, Supuran CT.. (2014) Discovery of a new family of carbonic anhydrases in the malaria pathogen Plasmodium falciparum--the η-carbonic anhydrases., 24 (18): [PMID:25168745] [10.1016/j.bmcl.2014.08.015] |
| 329. Vullo D, Del Prete S, Osman SM, Scozzafava A, Alothman Z, Supuran CT, Capasso C.. (2014) Anion inhibition study of the β-class carbonic anhydrase (PgiCAb) from the oral pathogen Porphyromonas gingivalis., 24 (18): [PMID:25168748] [10.1016/j.bmcl.2014.08.014] |
| 330. Abdel-Aziz AA, El-Azab AS, Ceruso M, Supuran CT.. (2014) Carbonic anhydrase inhibitory activity of sulfonamides and carboxylic acids incorporating cyclic imide scaffolds., 24 (22): [PMID:25442309] [10.1016/j.bmcl.2014.09.076] |
| 331. Schwarz S, Sommerwerk S, Lucas SD, Heller L, Csuk R.. (2014) Sulfamates of methyl triterpenoates are effective and competitive inhibitors of carbonic anhydrase II., 86 [PMID:25147151] [10.1016/j.ejmech.2014.08.051] |
| 332. Rosatelli E, Carotti A, Ceruso M, Supuran CT, Gioiello A.. (2014) Flow synthesis and biological activity of aryl sulfonamides as selective carbonic anhydrase IX and XII inhibitors., 24 (15): [PMID:24948563] [10.1016/j.bmcl.2014.05.086] |
| 333. Bozdag M, Pinard M, Carta F, Masini E, Scozzafava A, McKenna R, Supuran CT.. (2014) A class of 4-sulfamoylphenyl-ω-aminoalkyl ethers with effective carbonic anhydrase inhibitory action and antiglaucoma effects., 57 (22): [PMID:25358036] [10.1021/jm501497m] |
| 334. Dudutienė V, Matulienė J, Smirnov A, Timm DD, Zubrienė A, Baranauskienė L, Morkūnaite V, Smirnovienė J, Michailovienė V, Juozapaitienė V, Mickevičiūtė A, Kazokaitė J, Bakšytė S, Kasiliauskaitė A, Jachno J, Revuckienė J, Kišonaitė M, Pilipuitytė V, Ivanauskaitė E, Milinavičiūtė G, Smirnovas V, Petrikaitė V, Kairys V, Petrauskas V, Norvaišas P, Lingė D, Gibieža P, Capkauskaitė E, Zakšauskas A, Kazlauskas E, Manakova E, Gražulis S, Ladbury JE, Matulis D.. (2014) Discovery and characterization of novel selective inhibitors of carbonic anhydrase IX., 57 (22): [PMID:25358084] [10.1021/jm501003k] |
| 335. Pala N, Micheletto L, Sechi M, Aggarwal M, Carta F, McKenna R, Supuran CT.. (2014) Carbonic Anhydrase Inhibition with Benzenesulfonamides and Tetrafluorobenzenesulfonamides Obtained via Click Chemistry., 5 (8): [PMID:25147616] [10.1021/ml500196t] |
| 336. Ceruso M, Del Prete S, AlOthman Z, Osman SM, Scozzafava A, Capasso C, Supuran CT.. (2014) Synthesis of sulfonamides with effective inhibitory action against Porphyromonas gingivalis γ-carbonic anhydrase., 24 (16): [PMID:25011913] [10.1016/j.bmcl.2014.06.024] |
| 337. Ceruso M, Antel S, Vullo D, Scozzafava A, Supuran CT.. (2014) Inhibition studies of new ureido-substituted sulfonamides incorporating a GABA moiety against human carbonic anhydrase isoforms I-XIV., 22 (24): [PMID:25468040] [10.1016/j.bmc.2014.10.041] |
| 338. Sławiński J, Brzozowski Z, Żołnowska B, Szafrański K, Pogorzelska A, Vullo D, Supuran CT.. (2014) Synthesis of a new series of N⁴-substituted 4-(2-aminoethyl)benzenesulfonamides and their inhibitory effect on human carbonic anhydrase cytosolic isozymes I and II and transmembrane tumor-associated isozymes IX and XII., 84 [PMID:25016228] [10.1016/j.ejmech.2014.06.074] |
| 339. Sarikaya B, Ceruso M, Carta F, Supuran CT.. (2014) Inhibition of carbonic anhydrase isoforms I, II, IX and XII with novel Schiff bases: identification of selective inhibitors for the tumor-associated isoforms over the cytosolic ones., 22 (21): [PMID:25267005] [10.1016/j.bmc.2014.09.021] |
| 340. Vullo D, Del Prete S, Fisher GM, Andrews KT, Poulsen SA, Capasso C, Supuran CT.. (2015) Sulfonamide inhibition studies of the η-class carbonic anhydrase from the malaria pathogen Plasmodium falciparum., 23 (3): [PMID:25533402] [10.1016/j.bmc.2014.12.009] |
| 341. Bozdag M, Carta F, Vullo D, Akdemir A, Isik S, Lanzi C, Scozzafava A, Masini E, Supuran CT.. (2015) Synthesis of a new series of dithiocarbamates with effective human carbonic anhydrase inhibitory activity and antiglaucoma action., 23 (10): [PMID:25846066] [10.1016/j.bmc.2015.03.068] |
| 342. Mojzych M, Karczmarzyk Z, Wysocki W, Ceruso M, Supuran CT, Kryštof V, Urbańczyk-Lipkowska Z, Kalicki P.. (2015) New approaches to the synthesis of sildenafil analogues and their enzyme inhibitory activity., 23 (7): [PMID:25757603] [10.1016/j.bmc.2015.02.026] |
| 343. Yıldırım A, Atmaca U, Keskin A, Topal M, Çelik M, Gülçin İ, Supuran CT.. (2015) N-Acylsulfonamides strongly inhibit human carbonic anhydrase isoenzymes I and II., 23 (10): [PMID:25863492] [10.1016/j.bmc.2014.12.054] |
| 344. Syrjänen L, Kuuslahti M, Tolvanen M, Vullo D, Parkkila S, Supuran CT.. (2015) The β-carbonic anhydrase from the malaria mosquito Anopheles gambiae is highly inhibited by sulfonamides., 23 (10): [PMID:25882523] [10.1016/j.bmc.2015.03.081] |
| 345. Grandane A, Tanc M, Žalubovskis R, Supuran CT.. (2015) Synthesis of 6-aryl-substituted sulfocoumarins and investigation of their carbonic anhydrase inhibitory action., 23 (7): [PMID:25753329] [10.1016/j.bmc.2015.02.023] |
| 346. Carta F, Di Cesare Mannelli L, Pinard M, Ghelardini C, Scozzafava A, McKenna R, Supuran CT.. (2015) A class of sulfonamide carbonic anhydrase inhibitors with neuropathic pain modulating effects., 23 (8): [PMID:25766630] [10.1016/j.bmc.2015.02.027] |
| 347. Vullo D, De Luca V, Del Prete S, Carginale V, Scozzafava A, Capasso C, Supuran CT.. (2015) Sulfonamide inhibition studies of the γ-carbonic anhydrase from the Antarctic cyanobacterium Nostoc commune., 23 (8): [PMID:25773015] [10.1016/j.bmc.2015.02.045] |
| 348. Al-Rashida M, Ejaz SA, Ali S, Shaukat A, Hamayoun M, Ahmed M, Iqbal J.. (2015) Diarylsulfonamides and their bioisosteres as dual inhibitors of alkaline phosphatase and carbonic anhydrase: Structure activity relationship and molecular modelling studies., 23 (10): [PMID:25865133] [10.1016/j.bmc.2015.03.054] |
| 349. Tanpure RP, Ren B, Peat TS, Bornaghi LF, Vullo D, Supuran CT, Poulsen SA.. (2015) Carbonic anhydrase inhibitors with dual-tail moieties to match the hydrophobic and hydrophilic halves of the carbonic anhydrase active site., 58 (3): [PMID:25581127] [10.1021/jm501798g] |
| 350. Awadallah FM, El-Waei TA, Hanna MM, Abbas SE, Ceruso M, Oz BE, Guler OO, Supuran CT.. (2015) Synthesis, carbonic anhydrase inhibition and cytotoxic activity of novel chromone-based sulfonamide derivatives., 96 [PMID:25912674] [10.1016/j.ejmech.2015.04.033] |
| 351. Durgun M, Turkmen H, Ceruso M, Supuran CT.. (2015) Synthesis of Schiff base derivatives of 4-(2-aminoethyl)-benzenesulfonamide with inhibitory activity against carbonic anhydrase isoforms I, II, IX and XII., 25 (11): [PMID:25913118] [10.1016/j.bmcl.2015.04.007] |
| 352. Dedeoglu N, DeLuca V, Isik S, Yildirim H, Kockar F, Capasso C, Supuran CT.. (2015) Sulfonamide inhibition study of the β-class carbonic anhydrase from the caries producing pathogen Streptococcus mutans., 25 (11): [PMID:25913199] [10.1016/j.bmcl.2015.04.037] |
| 353. Grandane A, Tanc M, Di Cesare Mannelli L, Carta F, Ghelardini C, Žalubovskis R, Supuran CT.. (2015) 6-Substituted sulfocoumarins are selective carbonic anhdydrase IX and XII inhibitors with significant cytotoxicity against colorectal cancer cells., 58 (9): [PMID:25875209] [10.1021/acs.jmedchem.5b00523] |
| 354. PubChem BioAssay data set, |
| 355. Mojzych M, Ceruso M, Bielawska A, Bielawski K, Fornal E, Supuran CT.. (2015) New pyrazolo[4,3-e][1,2,4]triazine sulfonamides as carbonic anhydrase inhibitors., 23 (13): [PMID:25921266] [10.1016/j.bmc.2015.04.011] |
| 356. Akıncıoğlu A, Akıncıoğlu H, Gülçin İ, Durdagi S, Supuran CT, Göksu S.. (2015) Discovery of potent carbonic anhydrase and acetylcholine esterase inhibitors: novel sulfamoylcarbamates and sulfamides derived from acetophenones., 23 (13): [PMID:25921269] [10.1016/j.bmc.2015.04.019] |
| 357. Carradori S, Mollica A, Ceruso M, D'Ascenzio M, De Monte C, Chimenti P, Sabia R, Akdemir A, Supuran CT.. (2015) New amide derivatives of Probenecid as selective inhibitors of carbonic anhydrase IX and XII: biological evaluation and molecular modelling studies., 23 (13): [PMID:26007302] [10.1016/j.bmc.2015.05.013] |
| 358. Cvijetić IN, Tanç M, Juranić IO, Verbić TŽ, Supuran CT, Drakulić BJ.. (2015) 5-Aryl-1H-pyrazole-3-carboxylic acids as selective inhibitors of human carbonic anhydrases IX and XII., 23 (15): [PMID:26088336] [10.1016/j.bmc.2015.05.052] |
| 359. De Luca V, Vullo D, Del Prete S, Carginale V, Scozzafava A, Osman SM, AlOthman Z, Supuran CT, Capasso C.. (2015) Cloning, characterization and anion inhibition studies of a new γ-carbonic anhydrase from the Antarctic bacterium Pseudoalteromonas haloplanktis., 23 (15): [PMID:26145820] [10.1016/j.bmc.2015.06.021] |
| 360. Ibrahim DA, Lasheen DS, Zaky MY, Ibrahim AW, Vullo D, Ceruso M, Supuran CT, Abou El Ella DA.. (2015) Design and synthesis of benzothiazole-6-sulfonamides acting as highly potent inhibitors of carbonic anhydrase isoforms I, II, IX and XII., 23 (15): [PMID:26048024] [10.1016/j.bmc.2015.05.019] |
| 361. Pinard MA, Lotlikar SR, Boone CD, Vullo D, Supuran CT, Patrauchan MA, McKenna R.. (2015) Structure and inhibition studies of a type II beta-carbonic anhydrase psCA3 from Pseudomonas aeruginosa., 23 (15): [PMID:26068018] [10.1016/j.bmc.2015.05.029] |
| 362. Ceruso M, Carta F, Osman SM, Alothman Z, Monti SM, Supuran CT.. (2015) Inhibition studies of bacterial, fungal and protozoan β-class carbonic anhydrases with Schiff bases incorporating sulfonamide moieties., 23 (15): [PMID:26145821] [10.1016/j.bmc.2015.06.050] |
| 363. Meleddu R, Maccioni E, Distinto S, Bianco G, Melis C, Alcaro S, Cottiglia F, Ceruso M, Supuran CT.. (2015) New 4-[(3-cyclohexyl-4-aryl-2,3-dihydro-1,3-thiazol-2-ylidene)amino]benzene-1-sulfonamides, synthesis and inhibitory activity toward carbonic anhydrase I, II, IX, XII., 25 (16): [PMID:26073006] [10.1016/j.bmcl.2015.05.076] |
| 364. Khloya P, Ceruso M, Ram S, Supuran CT, Sharma PK.. (2015) Sulfonamide bearing pyrazolylpyrazolines as potent inhibitors of carbonic anhydrase isoforms I, II, IX and XII., 25 (16): [PMID:26105196] [10.1016/j.bmcl.2015.05.096] |
| 365. Mahon BP, Lomelino CL, Ladwig J, Rankin GM, Driscoll JM, Salguero AL, Pinard MA, Vullo D, Supuran CT, Poulsen SA, McKenna R.. (2015) Mapping Selective Inhibition of the Cancer-Related Carbonic Anhydrase IX Using Structure-Activity Relationships of Glucosyl-Based Sulfamates., 58 (16): [PMID:26203869] [10.1021/acs.jmedchem.5b00845] |
| 366. Congiu C, Onnis V, Deplano A, Balboni G, Ceruso M, Supuran CT.. (2015) Synthesis and carbonic anhydrase I, II, IX and XII inhibitory activity of sulfamates incorporating piperazinyl-ureido moieties., 23 (17): [PMID:26233796] [10.1016/j.bmc.2015.07.024] |
| 367. Güney M, Çavdar H, Şentürk M, Ekinci D.. (2015) Synthesis and carbonic anhydrase inhibitory properties of novel uracil derivatives., 25 (16): [PMID:26073005] [10.1016/j.bmcl.2015.05.073] |
| 368. Mollica A, Costante R, Akdemir A, Carradori S, Stefanucci A, Macedonio G, Ceruso M, Supuran CT.. (2015) Exploring new Probenecid-based carbonic anhydrase inhibitors: Synthesis, biological evaluation and docking studies., 23 (17): [PMID:26264840] [10.1016/j.bmc.2015.07.066] |
| 369. Vullo D, De Luca V, Del Prete S, Carginale V, Scozzafava A, Capasso C, Supuran CT.. (2015) Sulfonamide inhibition studies of the γ-carbonic anhydrase from the Antarctic bacterium Pseudoalteromonas haloplanktis., 25 (17): [PMID:26174556] [10.1016/j.bmcl.2015.06.079] |
| 370. Ombouma J, Vullo D, Dumy P, Supuran CT, Winum JY.. (2015) Carbonic Anhydrase Glycoinhibitors belonging to the Aminoxysulfonamide Series., 6 (7): [PMID:26191373] [10.1021/acsmedchemlett.5b00175] |
| 371. Congiu C, Onnis V, Deplano A, Balboni G, Dedeoglu N, Supuran CT.. (2015) Synthesis of sulfonamides incorporating piperazinyl-ureido moieties and their carbonic anhydrase I, II, IX and XII inhibitory activity., 25 (18): [PMID:26233435] [10.1016/j.bmcl.2015.07.060] |
| 372. Rankin GM, Vullo D, Supuran CT, Poulsen SA.. (2015) Phosphate Chemical Probes Designed for Location Specific Inhibition of Intracellular Carbonic Anhydrases., 58 (18): [PMID:26347950] [10.1021/acs.jmedchem.5b01228] |
| 373. Esirden İ, Ulus R, Aday B, Tanç M, Supuran CT, Kaya M.. (2015) Synthesis of novel acridine bis-sulfonamides with effective inhibitory activity against the carbonic anhydrase isoforms I, II, IX and XII., 23 (20): [PMID:26422787] [10.1016/j.bmc.2015.09.022] |
| 374. Nocentini A, Carta F, Ceruso M, Bartolucci G, Supuran CT.. (2015) Click-tailed coumarins with potent and selective inhibitory action against the tumor-associated carbonic anhydrases IX and XII., 23 (21): [PMID:26432607] [10.1016/j.bmc.2015.09.041] |
| 375. Karioti A, Ceruso M, Carta F, Bilia AR, Supuran CT.. (2015) New natural product carbonic anhydrase inhibitors incorporating phenol moieties., 23 (22): [PMID:26498393] [10.1016/j.bmc.2015.10.018] |
| 376. Carta F, Osman SM, Vullo D, AlOthman Z, Del Prete S, Capasso C, Supuran CT.. (2015) Poly(amidoamine) dendrimers show carbonic anhydrase inhibitory activity against α-, β-, γ- and η-class enzymes., 23 (21): [PMID:26476668] [10.1016/j.bmc.2015.10.006] |
| 377. La Regina G, Coluccia A, Famiglini V, Pelliccia S, Monti L, Vullo D, Nuti E, Alterio V, De Simone G, Monti SM, Pan P, Parkkila S, Supuran CT, Rossello A, Silvestri R.. (2015) Discovery of 1,1'-Biphenyl-4-sulfonamides as a New Class of Potent and Selective Carbonic Anhydrase XIV Inhibitors., 58 (21): [PMID:26497049] [10.1021/acs.jmedchem.5b01144] |
| 378. Ibrahim HS, Abou-Seri SM, Tanc M, Elaasser MM, Abdel-Aziz HA, Supuran CT.. (2015) Isatin-pyrazole benzenesulfonamide hybrids potently inhibit tumor-associated carbonic anhydrase isoforms IX and XII., 103 [PMID:26408817] [10.1016/j.ejmech.2015.09.021] |
| 379. Işık S, Vullo D, Durdagi S, Ekinci D, Şentürk M, Çetin A, Şentürk E, Supuran CT.. (2015) Interaction of carbonic anhydrase isozymes I, II, and IX with some pyridine and phenol hydrazinecarbothioamide derivatives., 25 (23): [PMID:26520662] [10.1016/j.bmcl.2015.10.021] |
| 380. Cincinelli A, Martellini T, Vullo D, Supuran CT.. (2015) Anion and sulfonamide inhibition studies of an α-carbonic anhydrase from the Antarctic hemoglobinless fish Chionodraco hamatus., 25 (23): [PMID:26525863] [10.1016/j.bmcl.2015.10.074] |
| 381. El-Azab AS, Abdel-Aziz AA, Ayyad RR, Ceruso M, Supuran CT.. (2016) Inhibition of carbonic anhydrase isoforms I, II, IV, VII and XII with carboxylates and sulfonamides incorporating phthalimide/phthalic anhydride scaffolds., 24 (1): [PMID:26678172] [10.1016/j.bmc.2015.11.034] |
| 382. Carta F, Ferraroni M, Scozzafava A, Supuran CT.. (2016) Fluorescent sulfonamide carbonic anhydrase inhibitors incorporating 1,2,3-triazole moieties: Kinetic and X-ray crystallographic studies., 24 (2): [PMID:26682703] [10.1016/j.bmc.2015.11.031] |
| 383. Vullo D, Bhatt A, Mahon BP, McKenna R, Supuran CT.. (2016) Sulfonamide inhibition studies of the α-carbonic anhydrase from the gammaproteobacterium Thiomicrospira crunogena XCL-2, TcruCA., 26 (2): [PMID:26691758] [10.1016/j.bmcl.2015.11.104] |
| 384. De Luca V, Vullo D, Del Prete S, Carginale V, Osman SM, AlOthman Z, Supuran CT, Capasso C.. (2016) Cloning, characterization and anion inhibition studies of a γ-carbonic anhydrase from the Antarctic bacterium Colwellia psychrerythraea., 24 (4): [PMID:26778292] [10.1016/j.bmc.2016.01.005] |
| 385. Villalba ML, Palestro P, Ceruso M, Gonzalez Funes JL, Talevi A, Bruno Blanch L, Supuran CT, Gavernet L.. (2016) Sulfamide derivatives with selective carbonic anhydrase VII inhibitory action., 24 (4): [PMID:26795114] [10.1016/j.bmc.2016.01.012] |
| 386. Barresi E, Salerno S, Marini AM, Taliani S, La Motta C, Simorini F, Da Settimo F, Vullo D, Supuran CT.. (2016) Sulfonamides incorporating heteropolycyclic scaffolds show potent inhibitory action against carbonic anhydrase isoforms I, II, IX and XII., 24 (4): [PMID:26796953] [10.1016/j.bmc.2016.01.018] |
| 387. Durgun M, Turkmen H, Ceruso M, Supuran CT.. (2016) Synthesis of 4-sulfamoylphenyl-benzylamine derivatives with inhibitory activity against human carbonic anhydrase isoforms I, II, IX and XII., 24 (5): [PMID:26803577] [10.1016/j.bmc.2016.01.020] |
| 388. Yaseen R, Ekinci D, Senturk M, Hameed AD, Ovais S, Rathore P, Samim M, Javed K, Supuran CT.. (2016) Pyridazinone substituted benzenesulfonamides as potent carbonic anhydrase inhibitors., 26 (4): [PMID:26804228] [10.1016/j.bmcl.2015.12.016] |
| 389. Carradori S, Secci D, De Monte C, Mollica A, Ceruso M, Akdemir A, Sobolev AP, Codispoti R, De Cosmi F, Guglielmi P, Supuran CT.. (2016) A novel library of saccharin and acesulfame derivatives as potent and selective inhibitors of carbonic anhydrase IX and XII isoforms., 24 (5): [PMID:26810710] [10.1016/j.bmc.2016.01.038] |
| 390. Lomelino CL, Mahon BP, McKenna R, Carta F, Supuran CT.. (2016) Kinetic and X-ray crystallographic investigations on carbonic anhydrase isoforms I, II, IX and XII of a thioureido analog of SLC-0111., 24 (5): [PMID:26810836] [10.1016/j.bmc.2016.01.019] |
| 391. Del Prete S, Vullo D, De Luca V, Carginale V, Ferraroni M, Osman SM, AlOthman Z, Supuran CT, Capasso C.. (2016) Sulfonamide inhibition studies of the β-carbonic anhydrase from the pathogenic bacterium Vibrio cholerae., 24 (5): [PMID:26850377] [10.1016/j.bmc.2016.01.037] |
| 392. Ferraroni M, Carta F, Scozzafava A, Supuran CT.. (2016) Thioxocoumarins Show an Alternative Carbonic Anhydrase Inhibition Mechanism Compared to Coumarins., 59 (1): [PMID:26688270] [10.1021/acs.jmedchem.5b01720] |
| 393. Eldehna WM, Fares M, Ceruso M, Ghabbour HA, Abou-Seri SM, Abdel-Aziz HA, Abou El Ella DA, Supuran CT.. (2016) Amido/ureidosubstituted benzenesulfonamides-isatin conjugates as low nanomolar/subnanomolar inhibitors of the tumor-associated carbonic anhydrase isoform XII., 110 [PMID:26840366] [10.1016/j.ejmech.2016.01.030] |
| 394. Vullo D, Del Prete S, De Luca V, Carginale V, Ferraroni M, Dedeoglu N, Osman SM, AlOthman Z, Capasso C, Supuran CT.. (2016) Anion inhibition studies of the β-carbonic anhydrase from the pathogenic bacterium Vibrio cholerae., 26 (5): [PMID:26853167] [10.1016/j.bmcl.2016.01.072] |
| 395. Alafeefy AM, Carta F, Ceruso M, Al-Tamimi AM, Al-Kahtani AA, Supuran CT.. (2016) Development of 3-(4-aminosulphonyl)-phenyl-2-mercapto-3H-quinazolin-4-ones as inhibitors of carbonic anhydrase isoforms involved in tumorigenesis and glaucoma., 24 (6): [PMID:26875933] [10.1016/j.bmc.2016.02.011] |
| 396. Vullo D, De Luca V, Del Prete S, Carginale V, Scozzafava A, Osman SM, AlOthman Z, Capasso C, Supuran CT.. (2016) Sulfonamide inhibition studies of the γ-carbonic anhydrase from the Antarctic bacterium Colwellia psychrerythraea., 26 (4): [PMID:26832216] [10.1016/j.bmcl.2016.01.023] |
| 397. Cornelio B, Laronze-Cochard M, Ceruso M, Ferraroni M, Rance GA, Carta F, Khlobystov AN, Fontana A, Supuran CT, Sapi J.. (2016) 4-Arylbenzenesulfonamides as Human Carbonic Anhydrase Inhibitors (hCAIs): Synthesis by Pd Nanocatalyst-Mediated Suzuki-Miyaura Reaction, Enzyme Inhibition, and X-ray Crystallographic Studies., 59 (2): [PMID:26741028] [10.1021/acs.jmedchem.5b01771] |
| 398. Eminoğlu A, Vullo D, Aşık A, Çolak DN, Çanakçı S, Beldüz AO, Supuran CT.. (2016) Sulfonamide inhibition studies of the β-carbonic anhydrase from the newly discovered bacterium Enterobacter sp. B13., 26 (7): [PMID:26920803] [10.1016/j.bmcl.2016.02.032] |
| 399. Akdemir A, Güzel-Akdemir Ö, Karalı N, Supuran CT.. (2016) Isatin analogs as novel inhibitors of Candida spp. β-carbonic anhydrase enzymes., 24 (8): [PMID:26951893] [10.1016/j.bmc.2016.02.036] |
| 400. Del Prete S, Vullo D, De Luca V, Carginale V, Osman SM, AlOthman Z, Supuran CT, Capasso C.. (2016) Comparison of the sulfonamide inhibition profiles of the α-, β- and γ-carbonic anhydrases from the pathogenic bacterium Vibrio cholerae., 26 (8): [PMID:26972117] [10.1016/j.bmcl.2016.03.014] |
| 401. Özgeriş B, Göksu S, Polat Köse L, Gülçin İ, Salmas RE, Durdagi S, Tümer F, Supuran CT.. (2016) Acetylcholinesterase and carbonic anhydrase inhibitory properties of novel urea and sulfamide derivatives incorporating dopaminergic 2-aminotetralin scaffolds., 24 (10): [PMID:27068142] [10.1016/j.bmc.2016.04.002] |
| 402. Chandak N, Ceruso M, Supuran CT, Sharma PK.. (2016) Novel sulfonamide bearing coumarin scaffolds as selective inhibitors of tumor associated carbonic anhydrase isoforms IX and XII., 24 (13): [PMID:27137360] [10.1016/j.bmc.2016.04.052] |
| 403. Kumar S, Ceruso M, Tuccinardi T, Supuran CT, Sharma PK.. (2016) Pyrazolylbenzo[d]imidazoles as new potent and selective inhibitors of carbonic anhydrase isoforms hCA IX and XII., 24 (13): [PMID:27166574] [10.1016/j.bmc.2016.04.061] |
| 404. Abdel Gawad NM, Amin NH, Elsaadi MT, Mohamed FM, Angeli A, De Luca V, Capasso C, Supuran CT.. (2016) Synthesis of 4-(thiazol-2-ylamino)-benzenesulfonamides with carbonic anhydrase I, II and IX inhibitory activity and cytotoxic effects against breast cancer cell lines., 24 (13): [PMID:27234893] [10.1016/j.bmc.2016.05.016] |
| 405. Ulus R, Aday B, Tanç M, Supuran CT, Kaya M.. (2016) Microwave assisted synthesis of novel acridine-acetazolamide conjugates and investigation of their inhibition effects on human carbonic anhydrase isoforms hCA I, II, IV and VII., 24 (16): [PMID:27298005] [10.1016/j.bmc.2016.05.064] |
| 406. Vullo D, Supuran CT, Scozzafava A, De Simone G, Monti SM, Alterio V, Carta F.. (2016) Kinetic and X-ray crystallographic investigations of substituted 2-thio-6-oxo-1,6-dihydropyrimidine-benzenesulfonamides acting as carbonic anhydrase inhibitors., 24 (16): [PMID:27316543] [10.1016/j.bmc.2016.06.005] |
| 407. Del Prete S, Vullo D, De Luca V, Carginale V, di Fonzo P, Osman SM, AlOthman Z, Supuran CT, Capasso C.. (2016) Anion inhibition profiles of α-, β- and γ-carbonic anhydrases from the pathogenic bacterium Vibrio cholerae., 24 (16): [PMID:27283786] [10.1016/j.bmc.2016.05.029] |
| 408. Nocentini A, Vullo D, Bartolucci G, Supuran CT.. (2016) N-Nitrosulfonamides: A new chemotype for carbonic anhydrase inhibition., 24 (16): [PMID:27290692] [10.1016/j.bmc.2016.05.072] |
| 409. Mujumdar P, Teruya K, Tonissen KF, Vullo D, Supuran CT, Peat TS, Poulsen SA.. (2016) An Unusual Natural Product Primary Sulfonamide: Synthesis, Carbonic Anhydrase Inhibition, and Protein X-ray Structures of Psammaplin C., 59 (11): [PMID:27172398] [10.1021/acs.jmedchem.6b00443] |
| 410. Akocak S, Alam MR, Shabana AM, Sanku RK, Vullo D, Thompson H, Swenson ER, Supuran CT, Ilies MA.. (2016) PEGylated Bis-Sulfonamide Carbonic Anhydrase Inhibitors Can Efficiently Control the Growth of Several Carbonic Anhydrase IX-Expressing Carcinomas., 59 (10): [PMID:27144971] [10.1021/acs.jmedchem.6b00492] |
| 411. Bozdag M, Alafeefy AM, Carta F, Ceruso M, Al-Tamimi AM, Al-Kahtani AA, Alasmary FA, Supuran CT.. (2016) Synthesis 4-[2-(2-mercapto-4-oxo-4H-quinazolin-3-yl)-ethyl]-benzenesulfonamides with subnanomolar carbonic anhydrase II and XII inhibitory properties., 24 (18): [PMID:27396930] [10.1016/j.bmc.2016.06.052] |
| 412. Supuran CT.. (2016) Bortezomib inhibits bacterial and fungal β-carbonic anhydrases., 24 (18): [PMID:27469982] [10.1016/j.bmc.2016.07.035] |
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| 417. Arslan T, Türkoğlu EA, Şentürk M, Supuran CT.. (2016) Synthesis and carbonic anhydrase inhibitory properties of novel chalcone substituted benzenesulfonamides., 26 (24): [PMID:27884694] [10.1016/j.bmcl.2016.11.017] |
| 418. Esirden İ, Tanç M, Supuran CT, Kaya M.. (2017) Microwave assisted synthesis of novel tetrazole/sulfonamide derivatives based on octahydroacridine, xanthene and chromene skeletons as inhibitors of the carbonic anhydrases isoforms I, II, IV and VII., 27 (1): [PMID:27876475] [10.1016/j.bmcl.2016.11.028] |
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| 421. Vullo D, Del Prete S, Nocentini A, Osman SM, AlOthman Z, Capasso C, Bozdag M, Carta F, Gratteri P, Supuran CT.. (2017) Dithiocarbamates effectively inhibit the β-carbonic anhydrase from the dandruff-producing fungus Malassezia globosa., 25 (3): [PMID:28057408] [10.1016/j.bmc.2016.12.040] |
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| 429. Bua S, Di Cesare Mannelli L, Vullo D, Ghelardini C, Bartolucci G, Scozzafava A, Supuran CT, Carta F.. (2017) Design and Synthesis of Novel Nonsteroidal Anti-Inflammatory Drugs and Carbonic Anhydrase Inhibitors Hybrids (NSAIDs-CAIs) for the Treatment of Rheumatoid Arthritis., 60 (3): [PMID:28075587] [10.1021/acs.jmedchem.6b01607] |
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| 441. Entezari Heravi Y, Bua S, Nocentini A, Del Prete S, Saboury AA, Sereshti H, Capasso C, Gratteri P, Supuran CT.. (2017) Inhibition of Malassezia globosa carbonic anhydrase with phenols., 25 (9): [PMID:28343756] [10.1016/j.bmc.2017.03.026] |
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| 449. Angeli A, Tanini D, Viglianisi C, Panzella L, Capperucci A, Menichetti S, Supuran CT.. (2017) Evaluation of selenide, diselenide and selenoheterocycle derivatives as carbonic anhydrase I, II, IV, VII and IX inhibitors., 25 (8): [PMID:28302505] [10.1016/j.bmc.2017.03.013] |
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| 453. Del Prete S, Vullo D, Osman SM, AlOthman Z, Supuran CT, Capasso C.. (2017) Sulfonamide inhibition profiles of the β-carbonic anhydrase from the pathogenic bacterium Francisella tularensis responsible of the febrile illness tularemia., 25 (13): [PMID:28511911] [10.1016/j.bmc.2017.05.007] |
| 454. Bi Y, Might M, Vankayalapati H, Kuberan B.. (2017) Repurposing of Proton Pump Inhibitors as first identified small molecule inhibitors of endo-β-N-acetylglucosaminidase (ENGase) for the treatment of NGLY1 deficiency, a rare genetic disease., 27 (13): [PMID:28512024] [10.1016/j.bmcl.2017.05.010] |
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| 457. Mohamed MA, Abdel-Aziz AA, Sakr HM, El-Azab AS, Bua S, Supuran CT.. (2017) Synthesis and human/bacterial carbonic anhydrase inhibition with a series of sulfonamides incorporating phthalimido moieties., 25 (8): [PMID:28318894] [10.1016/j.bmc.2017.03.017] |
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| 459. Supuran CT.. (2017) Bortezomib inhibits mammalian carbonic anhydrases., 25 (19): [PMID:28277280] [10.1016/j.bmc.2016.10.023] |
| 460. Ferraroni M, Lucarini L, Masini E, Korsakov M, Scozzafava A, Supuran CT, Krasavin M.. (2017) 1,3-Oxazole-based selective picomolar inhibitors of cytosolic human carbonic anhydrase II alleviate ocular hypertension in rabbits: Potency is supported by X-ray crystallography of two leads., 25 (17): [PMID:28728897] [10.1016/j.bmc.2017.06.054] |
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| 463. Ahmed G, Elger W, Meece F, Nair HB, Schneider B, Wyrwa R, Nickisch K.. (2017) A prodrug design for improved oral absorption and reduced hepatic interaction., 25 (20): [PMID:28886996] [10.1016/j.bmc.2017.08.027] |
| 464. Angapelly S, Ramya PVS, Angeli A, Del Prete S, Capasso C, Arifuddin M, Supuran CT.. (2017) Development of sulfonamides incorporating phenylacrylamido functionalities as carbonic anhydrase isoforms I, II, IX and XII inhibitors., 25 (20): [PMID:28887000] [10.1016/j.bmc.2017.08.047] |
| 465. Bianco G, Meleddu R, Distinto S, Cottiglia F, Gaspari M, Melis C, Corona A, Angius R, Angeli A, Taverna D, Alcaro S, Leitans J, Kazaks A, Tars K, Supuran CT, Maccioni E.. (2017) N-Acylbenzenesulfonamide Dihydro-1,3,4-oxadiazole Hybrids: Seeking Selectivity toward Carbonic Anhydrase Isoforms., 8 (8): [PMID:28835790] [10.1021/acsmedchemlett.7b00205] |
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| 470. Nocentini A, Bua S, Lomelino CL, McKenna R, Menicatti M, Bartolucci G, Tenci B, Di Cesare Mannelli L, Ghelardini C, Gratteri P, Supuran CT.. (2017) Discovery of New Sulfonamide Carbonic Anhydrase IX Inhibitors Incorporating Nitrogenous Bases., 8 (12): [PMID:29259754] [10.1021/acsmedchemlett.7b00399] |
| 471. Żołnowska B, Sławiński J, Szafrański K, Angeli A, Supuran CT, Kawiak A, Wieczór M, Zielińska J, Bączek T, Bartoszewska S.. (2018) Novel 2-(2-arylmethylthio-4-chloro-5-methylbenzenesulfonyl)-1-(1,3,5-triazin-2-ylamino)guanidine derivatives: Inhibition of human carbonic anhydrase cytosolic isozymes I and II and the transmembrane tumor-associated isozymes IX and XII, anticancer activity, and molecular modeling studies., 143 [PMID:29146134] [10.1016/j.ejmech.2017.11.005] |
| 472. De Luca L, Mancuso F, Ferro S, Buemi MR, Angeli A, Del Prete S, Capasso C, Supuran CT, Gitto R.. (2018) Inhibitory effects and structural insights for a novel series of coumarin-based compounds that selectively target human CA IX and CA XII carbonic anhydrases., 143 [PMID:29197732] [10.1016/j.ejmech.2017.11.061] |
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| 474. Ansari MF, Idrees D, Hassan MI, Ahmad K, Avecilla F, Azam A.. (2018) Design, synthesis and biological evaluation of novel pyridine-thiazolidinone derivatives as anticancer agents: Targeting human carbonic anhydrase IX., 144 [PMID:29289880] [10.1016/j.ejmech.2017.12.049] |
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| 487. Eldehna WM, Abo-Ashour MF, Nocentini A, Gratteri P, Eissa IH, Fares M, Ismael OE, Ghabbour HA, Elaasser MM, Abdel-Aziz HA, Supuran CT.. (2017) Novel 4/3-((4-oxo-5-(2-oxoindolin-3-ylidene)thiazolidin-2-ylidene)amino) benzenesulfonamides: Synthesis, carbonic anhydrase inhibitory activity, anticancer activity and molecular modelling studies., 139 [PMID:28802125] [10.1016/j.ejmech.2017.07.073] |
| 488. Cadoni R, Pala N, Lomelino C, Mahon BP, McKenna R, Dallocchio R, Dessì A, Carcelli M, Rogolino D, Sanna V, Rassu M, Iaccarino C, Vullo D, Supuran CT, Sechi M.. (2017) Exploring Heteroaryl-pyrazole Carboxylic Acids as Human Carbonic Anhydrase XII Inhibitors., 8 (9): [PMID:28947941] [10.1021/acsmedchemlett.7b00229] |
| 489. Angeli A, Tanini D, Peat TS, Di Cesare Mannelli L, Bartolucci G, Capperucci A, Ghelardini C, Supuran CT, Carta F.. (2017) Discovery of New Selenoureido Analogues of 4-(4-Fluorophenylureido)benzenesulfonamide as Carbonic Anhydrase Inhibitors., 8 (9): [PMID:28947945] [10.1021/acsmedchemlett.7b00280] |
| 490. Angeli A, Trallori E, Carta F, Di Cesare Mannelli L, Ghelardini C, Supuran CT.. (2018) Heterocoumarins Are Selective Carbonic Anhydrase IX and XII Inhibitors with Cytotoxic Effects against Cancer Cells Lines., 9 (9): [PMID:30258546] [10.1021/acsmedchemlett.8b00362] |
| 491. Vats L, Sharma V, Angeli A, Kumar R, Supuran CT, Sharma PK.. (2018) Synthesis of novel 4-functionalized 1,5-diaryl-1,2,3-triazoles containing benzenesulfonamide moiety as carbonic anhydrase I, II, IV and IX inhibitors., 150 [PMID:29571155] [10.1016/j.ejmech.2018.03.030] |
| 492. Bozdag M, Carta F, Ceruso M, Ferraroni M, McDonald PC, Dedhar S, Supuran CT.. (2018) Discovery of 4-Hydroxy-3-(3-(phenylureido)benzenesulfonamides as SLC-0111 Analogues for the Treatment of Hypoxic Tumors Overexpressing Carbonic Anhydrase IX., 61 (14): [PMID:29962205] [10.1021/acs.jmedchem.8b00770] |
| 493. Nocentini A, Trallori E, Singh S, Lomelino CL, Bartolucci G, Di Cesare Mannelli L, Ghelardini C, McKenna R, Gratteri P, Supuran CT.. (2018) 4-Hydroxy-3-nitro-5-ureido-benzenesulfonamides Selectively Target the Tumor-Associated Carbonic Anhydrase Isoforms IX and XII Showing Hypoxia-Enhanced Antiproliferative Profiles., 61 (23): [PMID:30433782] [10.1021/acs.jmedchem.8b01504] |
| 494. Angeli A, Ferraroni M, Supuran CT.. (2018) Famotidine, an Antiulcer Agent, Strongly Inhibits Helicobacter pylori and Human Carbonic Anhydrases., 9 (10): [PMID:30344913] [10.1021/acsmedchemlett.8b00334] |
| 495. Meleddu R, Distinto S, Cottiglia F, Angius R, Gaspari M, Taverna D, Melis C, Angeli A, Bianco G, Deplano S, Fois B, Del Prete S, Capasso C, Alcaro S, Ortuso F, Yanez M, Supuran CT, Maccioni E.. (2018) Tuning the Dual Inhibition of Carbonic Anhydrase and Cyclooxygenase by Dihydrothiazole Benzensulfonamides., 9 (10): [PMID:30344915] [10.1021/acsmedchemlett.8b00352] |
| 496. Mishra CB, Kumari S, Angeli A, Bua S, Buonanno M, Monti SM, Tiwari M, Supuran CT.. (2018) Discovery of potent anti-convulsant carbonic anhydrase inhibitors: Design, synthesis, in vitro and in vivo appraisal., 156 [PMID:30015076] [10.1016/j.ejmech.2018.07.019] |
| 497. Abo-Ashour MF, Eldehna WM, Nocentini A, Ibrahim HS, Bua S, Abou-Seri SM, Supuran CT.. (2018) Novel hydrazido benzenesulfonamides-isatin conjugates: Synthesis, carbonic anhydrase inhibitory activity and molecular modeling studies., 157 [PMID:30071407] [10.1016/j.ejmech.2018.07.054] |
| 498. Angeli A, Trallori E, Ferraroni M, Di Cesare Mannelli L, Ghelardini C, Supuran CT.. (2018) Discovery of new 2, 5-disubstituted 1,3-selenazoles as selective human carbonic anhydrase IX inhibitors with potent anti-tumor activity., 157 [PMID:30193219] [10.1016/j.ejmech.2018.08.096] |
| 499. Unpublished dataset, |
| 500. Franck Touret, Magali Gilles, Karine Barral, Antoine Nougairède, Etienne Decroly, Xavier de Lamballerie, Bruno Coutard. (2020) In vitro screening of a FDA approved chemical library reveals potential inhibitors of SARS-CoV-2 replication, [10.1101/2020.04.03.023846] |
| 501. Bernhard Ellinger, Denisa Bojkova, Andrea Zaliani, Jindrich Cinatl, Carsten Claussen, Sandra Westhaus, Jeanette Reinshagen, Maria Kuzikov, Markus Wolf, Gerd Geisslinger, Philip Gribbon, Sandra Ciesek. (2020) Identification of inhibitors of SARS-CoV-2 in-vitro cellular toxicity in human (Caco-2) cells using a large scale drug repurposing collection, [10.21203/rs.3.rs-23951/v1] |
| 502. Katie Heiser, Peter F. McLean, Chadwick T. Davis, Ben Fogelson, Hannah B. Gordon, Pamela Jacobson, Brett Hurst, Ben Miller, Ronald W. Alfa, Berton A. Earnshaw, Mason L. Victors, Yolanda T. Chong, Imran S. Haque, Adeline S. Low, Christopher C. Gibson. (2020) Identification of potential treatments for COVID-19 through artificial intelligence-enabled phenomic analysis of human cells infected with SARS-CoV-2, [10.1101/2020.04.21.054387] |
| 503. Larcher A, Nocentini A, Supuran CT, Winum JY, van der Lee A, Vasseur JJ, Laurencin D, Smietana M.. (2019) Bis-benzoxaboroles: Design, Synthesis, and Biological Evaluation as Carbonic Anhydrase Inhibitors., 10 (8): [PMID:31413806] [10.1021/acsmedchemlett.9b00252] |
| 504. Vats L, Kumar R, Bua S, Nocentini A, Gratteri P, Supuran CT, Sharma PK.. (2019) Continued exploration and tail approach synthesis of benzenesulfonamides containing triazole and dual triazole moieties as carbonic anhydrase I, II, IV and IX inhibitors., 183 [PMID:31539777] [10.1016/j.ejmech.2019.111698] |
| 505. Zengin Kurt B, Sonmez F, Ozturk D, Akdemir A, Angeli A, Supuran CT.. (2019) Synthesis of coumarin-sulfonamide derivatives and determination of their cytotoxicity, carbonic anhydrase inhibitory and molecular docking studies., 183 [PMID:31542715] [10.1016/j.ejmech.2019.111702] |
| 506. Abo-Ashour MF, Eldehna WM, Nocentini A, Bonardi A, Bua S, Ibrahim HS, Elaasser MM, Kryštof V, Jorda R, Gratteri P, Abou-Seri SM, Supuran CT.. (2019) 3-Hydrazinoisatin-based benzenesulfonamides as novel carbonic anhydrase inhibitors endowed with anticancer activity: Synthesis, in vitro biological evaluation and in silico insights., 184 [PMID:31629164] [10.1016/j.ejmech.2019.111768] |
| 507. Said MA, Eldehna WM, Nocentini A, Bonardi A, Fahim SH, Bua S, Soliman DH, Abdel-Aziz HA, Gratteri P, Abou-Seri SM, Supuran CT.. (2020) Synthesis, biological and molecular dynamics investigations with a series of triazolopyrimidine/triazole-based benzenesulfonamides as novel carbonic anhydrase inhibitors., 185 [PMID:31718943] [10.1016/j.ejmech.2019.111843] |
| 508. Zakšauskas A, Čapkauskaitė E, Jezepčikas L, Linkuvienė V, Paketurytė V, Smirnov A, Leitans J, Kazaks A, Dvinskis E, Manakova E, Gražulis S, Tars K, Matulis D.. (2020) Halogenated and di-substituted benzenesulfonamides as selective inhibitors of carbonic anhydrase isoforms., 185 [PMID:31740053] [10.1016/j.ejmech.2019.111825] |
| 509. Buemi MR, Di Fiore A, De Luca L, Angeli A, Mancuso F, Ferro S, Monti SM, Buonanno M, Russo E, De Sarro G, De Simone G, Supuran CT, Gitto R.. (2019) Exploring structural properties of potent human carbonic anhydrase inhibitors bearing a 4-(cycloalkylamino-1-carbonyl)benzenesulfonamide moiety., 163 [PMID:30530195] [10.1016/j.ejmech.2018.11.073] |
| 510. Mujumdar P, Kopecka J, Bua S, Supuran CT, Riganti C, Poulsen SA.. (2019) Carbonic Anhydrase XII Inhibitors Overcome Temozolomide Resistance in Glioblastoma., 62 (8): [PMID:30925064] [10.1021/acs.jmedchem.9b00282] |
| 511. Nocentini A, Lucidi A, Perut F, Massa A, Tomaselli D, Gratteri P, Baldini N, Rotili D, Mai A, Supuran CT.. (2019) α,γ-Diketocarboxylic Acids and Their Esters Act as Carbonic Anhydrase IX and XII Selective Inhibitors., 10 (4): [PMID:30996814] [10.1021/acsmedchemlett.9b00023] |
| 512. Angeli A, Etxebeste-Mitxeltorena M, Sanmartín C, Espuelas S, Moreno E, Azqueta A, Parkkila S, Carta F, Supuran CT.. (2020) Tellurides Bearing Sulfonamides as Novel Inhibitors of Leishmanial Carbonic Anhydrase with Potent Antileishmanial Activity., 63 (8): [PMID:32223141] [10.1021/acs.jmedchem.0c00211] |
| 513. Angeli A, Di Cesare Mannelli L, Ghelardini C, Peat TS, Bartolucci G, Menicatti M, Carta F, Supuran CT.. (2019) Benzensulfonamides bearing spyrohydantoin moieties act as potent inhibitors of human carbonic anhydrases II and VII and show neuropathic pain attenuating effects., 177 [PMID:31136893] [10.1016/j.ejmech.2019.05.058] |
| 514. Allam HA, Fahim SH, F Abo-Ashour M, Nocentini A, Elbakry ME, Abdelrahman MA, Eldehna WM, Ibrahim HS, Supuran CT.. (2019) Application of hydrazino and hydrazido linkers to connect benzenesulfonamides with hydrophilic/phobic tails for targeting the middle region of human carbonic anhydrases active site: Selective inhibitors of hCA IX., 179 [PMID:31276899] [10.1016/j.ejmech.2019.06.081] |
| 515. D'Ascenzio M, Secci D, Carradori S, Zara S, Guglielmi P, Cirilli R, Pierini M, Poli G, Tuccinardi T, Angeli A, Supuran CT.. (2020) 1,3-Dipolar Cycloaddition, HPLC Enantioseparation, and Docking Studies of Saccharin/Isoxazole and Saccharin/Isoxazoline Derivatives as Selective Carbonic Anhydrase IX and XII Inhibitors., 63 (5): [PMID:31972093] [10.1021/acs.jmedchem.9b01434] |
| 516. Berrino E, Milazzo L, Micheli L, Vullo D, Angeli A, Bozdag M, Nocentini A, Menicatti M, Bartolucci G, di Cesare Mannelli L, Ghelardini C, Supuran CT, Carta F.. (2019) Synthesis and Evaluation of Carbonic Anhydrase Inhibitors with Carbon Monoxide Releasing Properties for the Management of Rheumatoid Arthritis., 62 (15): [PMID:31287314] [10.1021/acs.jmedchem.9b00845] |
| 517. Costa G, Carta F, Ambrosio FA, Artese A, Ortuso F, Moraca F, Rocca R, Romeo I, Lupia A, Maruca A, Bagetta D, Catalano R, Vullo D, Alcaro S, Supuran CT.. (2019) A computer-assisted discovery of novel potential anti-obesity compounds as selective carbonic anhydrase VA inhibitors., 181 [PMID:31387062] [10.1016/j.ejmech.2019.111565] |
| 518. El-Azab AS, Abdel-Aziz AA, Bua S, Nocentini A, AlSaif NA, Almehizia AA, Alanazi MM, Hefnawy MM, Supuran CT.. (2019) New anthranilic acid-incorporating N-benzenesulfonamidophthalimides as potent inhibitors of carbonic anhydrases I, II, IX, and XII: Synthesis, in vitro testing, and in silico assessment., 181 [PMID:31394463] [10.1016/j.ejmech.2019.111573] |
| 519. Tanini D, Ricci L, Capperucci A, Di Cesare Mannelli L, Ghelardini C, Peat TS, Carta F, Angeli A, Supuran CT.. (2019) Synthesis of novel tellurides bearing benzensulfonamide moiety as carbonic anhydrase inhibitors with antitumor activity., 181 [PMID:31401537] [10.1016/j.ejmech.2019.111586] |
| 520. Moi D, Nocentini A, Deplano A, Balboni G, Supuran CT, Onnis V.. (2019) Structure-activity relationship with pyrazoline-based aromatic sulfamates as carbonic anhydrase isoforms I, II, IX and XII inhibitors: Synthesis and biological evaluation., 182 [PMID:31472471] [10.1016/j.ejmech.2019.111638] |
| 521. Kalinin S, Nocentini A, Kovalenko A, Sharoyko V, Bonardi A, Angeli A, Gratteri P, Tennikova TB, Supuran CT, Krasavin M.. (2019) From random to rational: A discovery approach to selective subnanomolar inhibitors of human carbonic anhydrase IV based on the Castagnoli-Cushman multicomponent reaction., 182 [PMID:31476557] [10.1016/j.ejmech.2019.111642] |
| 522. Bozdag M, Ferraroni M, Ward C, Carta F, Bua S, Angeli A, Langdon SP, Kunkler IH, Al-Tamimi AS, Supuran CT.. (2019) Carbonic anhydrase inhibitors based on sorafenib scaffold: Design, synthesis, crystallographic investigation and effects on primary breast cancer cells., 182 [PMID:31419777] [10.1016/j.ejmech.2019.111600] |
| 523. Kalinin S, Valtari A, Ruponen M, Toropainen E, Kovalenko A, Nocentini A, Gureev M, Dar'in D, Urtti A, Supuran CT, Krasavin M.. (2019) Highly hydrophilic 1,3-oxazol-5-yl benzenesulfonamide inhibitors of carbonic anhydrase II for reduction of glaucoma-related intraocular pressure., 27 (21): [PMID:31515057] [10.1016/j.bmc.2019.115086] |
| 524. Swain B, Singh Digwal C, Angeli A, Alvala M, Singh P, Supuran CT, Arifuddin M.. (2019) Synthesis and exploration of 2-morpholino-4-phenylthiazol-5-yl acrylamide derivatives for their effects against carbonic anhydrase I, II, IX and XII isoforms as a non-sulfonamide class of inhibitors., 27 (21): [PMID:31515058] [10.1016/j.bmc.2019.115090] |
| 525. Liu L, Wang W, Huang J, Zhao Z, Li H, Xu Y.. (2018) Novel benzoyl thioureido benzene sulfonamides as highly potent and selective inhibitors of carbonic anhydrase IX: optimization and bioactive studies., 9 (12): [PMID:30746068] [10.1039/C8MD00392K] |
| 526. Tanini D, Capperucci A, Ferraroni M, Carta F, Angeli A, Supuran CT.. (2020) Direct and straightforward access to substituted alkyl selenols as novel carbonic anhydrase inhibitors., 185 [PMID:31693947] [10.1016/j.ejmech.2019.111811] |
| 527. Bua S, Lomelino C, Murray AB, Osman SM, ALOthman ZA, Bozdag M, Abdel-Aziz HA, Eldehna WM, McKenna R, Nocentini A, Supuran CT.. (2020) "A Sweet Combination": Developing Saccharin and Acesulfame K Structures for Selectively Targeting the Tumor-Associated Carbonic Anhydrases IX and XII., 63 (1): [PMID:31794211] [10.1021/acs.jmedchem.9b01669] |
| 528. Eldehna WM, Abo-Ashour MF, Nocentini A, El-Haggar RS, Bua S, Bonardi A, Al-Rashood ST, Hassan GS, Gratteri P, Abdel-Aziz HA, Supuran CT.. (2019) Enhancement of the tail hydrophobic interactions within the carbonic anhydrase IX active site via structural extension: Design and synthesis of novel N-substituted isatins-SLC-0111 hybrids as carbonic anhydrase inhibitors and antitumor agents., 162 [PMID:30445264] [10.1016/j.ejmech.2018.10.068] |
| 529. Krasavin M, Shetnev A, Baykov S, Kalinin S, Nocentini A, Sharoyko V, Poli G, Tuccinardi T, Korsakov M, Tennikova TB, Supuran CT.. (2019) Pyridazinone-substituted benzenesulfonamides display potent inhibition of membrane-bound human carbonic anhydrase IX and promising antiproliferative activity against cancer cell lines., 168 [PMID:30826507] [10.1016/j.ejmech.2019.02.044] |
| 530. Cornelio B, Laronze-Cochard M, Miambo R, De Grandis M, Riccioni R, Borisova B, Dontchev D, Machado C, Ceruso M, Fontana A, Supuran CT, Sapi J.. (2019) 5-Arylisothiazol-3(2H)-one-1,(1)-(di)oxides: A new class of selective tumor-associated carbonic anhydrases (hCA IX and XII) inhibitors., 175 [PMID:31071549] [10.1016/j.ejmech.2019.04.072] |
| 531. Zaraei SO, El-Gamal MI, Shafique Z, Amjad ST, Afridi S, Zaib S, Anbar HS, El-Gamal R, Iqbal J.. (2019) Sulfonate and sulfamate derivatives possessing benzofuran or benzothiophene nucleus as potent carbonic anhydrase II/IX/XII inhibitors., 27 (17): [PMID:31345748] [10.1016/j.bmc.2019.07.026] |
| 532. Lolak N, Akocak S, Bua S, Sanku RKK, Supuran CT.. (2019) Discovery of new ureido benzenesulfonamides incorporating 1,3,5-triazine moieties as carbonic anhydrase I, II, IX and XII inhibitors., 27 (8): [PMID:30846402] [10.1016/j.bmc.2019.03.001] |
| 533. Bua S, Lucarini L, Micheli L, Menicatti M, Bartolucci G, Selleri S, Di Cesare Mannelli L, Ghelardini C, Masini E, Carta F, Gratteri P, Nocentini A, Supuran CT.. (2020) Bioisosteric Development of Multitarget Nonsteroidal Anti-Inflammatory Drug-Carbonic Anhydrases Inhibitor Hybrids for the Management of Rheumatoid Arthritis., 63 (5): [PMID:31689108] [10.1021/acs.jmedchem.9b01130] |
| 534. Fares M, Eldehna WM, Bua S, Lanzi C, Lucarini L, Masini E, Peat TS, Abdel-Aziz HA, Nocentini A, Keller PA, Supuran CT.. (2020) Discovery of Potent Dual-Tailed Benzenesulfonamide Inhibitors of Human Carbonic Anhydrases Implicated in Glaucoma and in Vivo Profiling of Their Intraocular Pressure-Lowering Action., 63 (6): [PMID:32031797] [10.1021/acs.jmedchem.9b02090] |
| 535. Nocentini A, Alterio V, Bua S, Micheli L, Esposito D, Buonanno M, Bartolucci G, Osman SM, ALOthman ZA, Cirilli R, Pierini M, Monti SM, Di Cesare Mannelli L, Gratteri P, Ghelardini C, De Simone G, Supuran CT.. (2020) Phenyl(thio)phosphon(amid)ate Benzenesulfonamides as Potent and Selective Inhibitors of Human Carbonic Anhydrases II and VII Counteract Allodynia in a Mouse Model of Oxaliplatin-Induced Neuropathy., 63 (10): [PMID:32364386] [10.1021/acs.jmedchem.9b02135] |
| 536. Krasavin M, Shetnev A, Sharonova T, Baykov S, Kalinin S, Nocentini A, Sharoyko V, Poli G, Tuccinardi T, Presnukhina S, Tennikova TB, Supuran CT.. (2019) Continued exploration of 1,2,4-oxadiazole periphery for carbonic anhydrase-targeting primary arene sulfonamides: Discovery of subnanomolar inhibitors of membrane-bound hCA IX isoform that selectively kill cancer cells in hypoxic environment., 164 [PMID:30594030] [10.1016/j.ejmech.2018.12.049] |
| 537. Vullo D, Durante M, Di Leva FS, Cosconati S, Masini E, Scozzafava A, Novellino E, Supuran CT, Carta F.. (2016) Monothiocarbamates Strongly Inhibit Carbonic Anhydrases in Vitro and Possess Intraocular Pressure Lowering Activity in an Animal Model of Glaucoma., 59 (12): [PMID:27253845] [10.1021/acs.jmedchem.6b00462] |
| 538. Del Prete S, Vullo D, De Luca V, Carginale V, Osman SM, AlOthman Z, Supuran CT, Capasso C.. (2016) Cloning, expression, purification and sulfonamide inhibition profile of the complete domain of the η-carbonic anhydrase from Plasmodium falciparum., 26 (17): [PMID:27485387] [10.1016/j.bmcl.2016.07.060] |
| 539. Riafrecha LE, Bua S, Supuran CT, Colinas PA.. (2016) Synthesis and carbonic anhydrase inhibitory effects of new N-glycosylsulfonamides incorporating the phenol moiety., 26 (16): [PMID:27423482] [10.1016/j.bmcl.2016.07.015] |
| 540. Bonardi A, Vermelho AB, da Silva Cardoso V, de Souza Pereira MC, da Silva Lara L, Selleri S, Gratteri P, Supuran CT, Nocentini A.. (2019) N-Nitrosulfonamides as Carbonic Anhydrase Inhibitors: A Promising Chemotype for Targeting Chagas Disease and Leishmaniasis., 10 (4): [PMID:30996772] [10.1021/acsmedchemlett.8b00430] |
| 541. Maria Kuzikov, Elisa Costanzi, Jeanette Reinshagen, Francesca Esposito, Laura Vangeel, Markus Wolf, Bernhard Ellinger, Carsten Claussen, Gerd Geisslinger, Angela Corona, Daniela Iaconis, Carmine Talarico, Candida Manelfi, Rolando Cannalire, Giulia Rossetti, Jonas Gossen, Simone Albani, Francesco Musiani, Katja Herzog, Yang Ye, Barbara Giabbai, Nicola Demitri, Dirk Jochmans, Steven De Jonghe, Jasper Rymenants, Vincenzo Summa, Enzo Tramontano, Andrea R. Beccari, Pieter Leyssen, Paola Storici, Johan Neyts, Philip Gribbon, and Andrea Zaliani. (2020) Identification of inhibitors of SARS-Cov2 M-Pro enzymatic activity using a small molecule repurposing screen, [10.6019/CHEMBL4495564] |
| 542. Andrea Zaliani, Laura Vangeel, Jeanette Reinshagen, Daniela Iaconis, Maria Kuzikov, Oliver Keminer, Markus Wolf, Bernhard Ellinger, Francesca Esposito, Angela Corona, Enzo Tramontano, Candida Manelfi, Katja Herzog, Dirk Jochmans, Steven De Jonghe, Winston Chiu, Thibault Francken, Joost Schepers, Caroline Collard, Kayvan Abbasi, Carsten Claussen , Vincenzo Summa, Andrea R. Beccari, Johan Neyts, Philip Gribbon and Pieter Leyssen. (2020) Cytopathic SARS-Cov2 screening on VERO-E6 cells in a large repurposing effort, [10.6019/CHEMBL4495565] |
| 543. Johannes Zuegg, Alysha Elliott, Maite Amado, Emma Cowie, Ali Hinton, Geraldine Kaeslin, Angela Kavanagh, Anne Kunert, Gabriell Lowe, Soumya Ramu, Janet Reid, Robin Trauer, Mathilde Desselle, Ruth Neale, Karl Hansford, Mark Blascovich, Matthew Cooper. CO-ADD screening of NIH (USA) - Clinical Collection, [10.6019/CHEMBL4513141] |
| 544. Yang C, Feng Y, Yang X, Sun M, Li Z, Liu X, Lu L, Sun X, Zhang J, He X.. (2020) Synthesis and evaluation of 4-(1,3,4-oxadiazol-2-yl)-benzenesulfonamides as potent carbonic anhydrase inhibitors., 30 (2): [PMID:31859159] [10.1016/j.bmcl.2019.126874] |
| 545. Mancuso F, Di Fiore A, De Luca L, Angeli A, Monti SM, De Simone G, Supuran CT, Gitto R.. (2020) Looking toward the Rim of the Active Site Cavity of Druggable Human Carbonic Anhydrase Isoforms., 11 (5): [PMID:32435417] [10.1021/acsmedchemlett.0c00062] |
| 546. Berrino E, Angeli A, Zhdanov DD, Kiryukhina AP, Milaneschi A, De Luca A, Bozdag M, Carradori S, Selleri S, Bartolucci G, Peat TS, Ferraroni M, Supuran CT, Carta F.. (2020) Azidothymidine "Clicked" into 1,2,3-Triazoles: First Report on Carbonic Anhydrase-Telomerase Dual-Hybrid Inhibitors., 63 (13): [PMID:32463228] [10.1021/acs.jmedchem.0c00636] |
| 547. La Regina G, Puxeddu M, Nalli M, Vullo D, Gratteri P, Supuran CT, Nocentini A, Silvestri R.. (2020) Discovery of New 1,1'-Biphenyl-4-sulfonamides as Selective Subnanomolar Human Carbonic Anhydrase II Inhibitors., 11 (5): [PMID:32435363] [10.1021/acsmedchemlett.9b00437] |
| 548. Pratesi D, Matassini C, Goti A, Angeli A, Carta F, Supuran CT, Spanevello R, Cardona F.. (2020) Glycomimetic Based Approach toward Selective Carbonic Anhydrase Inhibitors., 11 (5): [PMID:32435377] [10.1021/acsmedchemlett.9b00590] |
| 549. Meleddu R, Distinto S, Cottiglia F, Angius R, Caboni P, Angeli A, Melis C, Deplano S, Alcaro S, Ortuso F, Supuran CT, Maccioni E.. (2020) New Dihydrothiazole Benzensulfonamides: Looking for Selectivity toward Carbonic Anhydrase Isoforms I, II, IX, and XII., 11 (5): [PMID:32435395] [10.1021/acsmedchemlett.9b00644] |
| 550. Eldehna WM, Nocentini A, Elsayed ZM, Al-Warhi T, Aljaeed N, Alotaibi OJ, Al-Sanea MM, Abdel-Aziz HA, Supuran CT.. (2020) Benzofuran-Based Carboxylic Acids as Carbonic Anhydrase Inhibitors and Antiproliferative Agents against Breast Cancer., 11 (5): [PMID:32435420] [10.1021/acsmedchemlett.0c00094] |
| 551. Bonardi A, Nocentini A, Bua S, Combs J, Lomelino C, Andring J, Lucarini L, Sgambellone S, Masini E, McKenna R, Gratteri P, Supuran CT.. (2020) Sulfonamide Inhibitors of Human Carbonic Anhydrases Designed through a Three-Tails Approach: Improving Ligand/Isoform Matching and Selectivity of Action., 63 (13): [PMID:32519851] [10.1021/acs.jmedchem.0c00733] |
| 552. Aneja B, Queen A, Khan P, Shamsi F, Hussain A, Hasan P, Rizvi MMA, Daniliuc CG, Alajmi MF, Mohsin M, Hassan MI, Abid M.. (2020) Design, synthesis & biological evaluation of ferulic acid-based small molecule inhibitors against tumor-associated carbonic anhydrase IX., 28 (9): [PMID:32209296] [10.1016/j.bmc.2020.115424] |
| 553. Grandane A, Nocentini A, Werner T, Zalubovskis R, Supuran CT.. (2020) Benzoxepinones: A new isoform-selective class of tumor associated carbonic anhydrase inhibitors., 28 (11): [PMID:32327349] [10.1016/j.bmc.2020.115496] |
| 554. Abdel-Mohsen HT, El Kerdawy AM, Omar MA, Berrino E, Abdelsamie AS, El Diwani HI, Supuran CT.. (2020) New thiopyrimidine-benzenesulfonamide conjugates as selective carbonic anhydrase II inhibitors: synthesis, in vitro biological evaluation, and molecular docking studies., 28 (5): [PMID:32007388] [10.1016/j.bmc.2020.115329] |
| 555. Ellen Van Damme. (2021) Screening of ~5500 FDA-approved drugs and clinical candidates for anti-SARS-CoV-2 activity, [10.6019/CHEMBL4651402] |
| 556. Andring JT,Fouch M,Akocak S,Angeli A,Supuran CT,Ilies MA,McKenna R. (2020) Structural Basis of Nanomolar Inhibition of Tumor-Associated Carbonic Anhydrase IX: X-Ray Crystallographic and Inhibition Study of Lipophilic Inhibitors with Acetazolamide Backbone., 63 (21.0): [PMID:33085484] [10.1021/acs.jmedchem.0c01390] |
| 557. Mishra CB,Kumari S,Angeli A,Bua S,Tiwari M,Supuran CT. (2018) Discovery of Benzenesulfonamide Derivatives as Carbonic Anhydrase Inhibitors with Effective Anticonvulsant Action: Design, Synthesis, and Pharmacological Evaluation., 61 (7): [PMID:29566486] [10.1021/acs.jmedchem.8b00208] |
| 558. Khalil OM,Kamal AM,Bua S,El Sayed Teba H,Nissan YM,Supuran CT. (2020) Pyrrolo and pyrrolopyrimidine sulfonamides act as cytotoxic agents in hypoxia via inhibition of transmembrane carbonic anhydrases., 188 [PMID:31901743] [10.1016/j.ejmech.2019.112021] |
| 559. Said MA,Eldehna WM,Nocentini A,Fahim SH,Bonardi A,Elgazar AA,Kryštof V,Soliman DH,Abdel-Aziz HA,Gratteri P,Abou-Seri SM,Supuran CT. (2020) Sulfonamide-based ring-fused analogues for CAN508 as novel carbonic anhydrase inhibitors endowed with antitumor activity: Design, synthesis, and in vitro biological evaluation., 189 [PMID:31972394] [10.1016/j.ejmech.2019.112019] |
| 560. Sharma V,Kumar R,Angeli A,Supuran CT,Sharma PK. (2020) Tail approach synthesis of novel benzenesulfonamides incorporating 1,3,4-oxadiazole hybrids as potent inhibitor of carbonic anhydrase I, II, IX, and XII isoenzymes., 193 [PMID:32203788] [10.1016/j.ejmech.2020.112219] |
| 561. Sağlık BN,Osmaniye D,Çevik UA,Levent S,Çavuşoğlu BK,Büyükemir O,Nezir D,Karaduman AB,Özkay Y,Koparal AS,Beydemir Ş,Kaplancıklı ZA. (2020) Synthesis, characterization and carbonic anhydrase I and II inhibitory evaluation of new sulfonamide derivatives bearing dithiocarbamate., 198 [PMID:32388113] [10.1016/j.ejmech.2020.112392] |
| 562. Grandāne A,Nocentini A,Domračeva I,Žalubovskis R,Supuran CT. (2020) Development of oxathiino[6,5-b]pyridine 2,2-dioxide derivatives as selective inhibitors of tumor-related carbonic anhydrases IX and XII., 200 [PMID:32460112] [10.1016/j.ejmech.2020.112300] |
| 563. Soliman AM,Ghorab MM,Bua S,Supuran CT. (2020) Iodoquinazolinones bearing benzenesulfonamide as human carbonic anhydrase I, II, IX and XII inhibitors: Synthesis, biological evaluation and radiosensitizing activity., 200 [PMID:32485534] [10.1016/j.ejmech.2020.112449] |
| 564. Ceni C,Catarzi D,Varano F,Ben DD,Marucci G,Buccioni M,Volpini R,Angeli A,Nocentini A,Gratteri P,Supuran CT,Colotta V. (2020) Discovery of first-in-class multi-target adenosine A receptor antagonists-carbonic anhydrase IX and XII inhibitors. 8-Amino-6-aryl-2-phenyl-1,2,4-triazolo [4,3-a]pyrazin-3-one derivatives as new potential antitumor agents., 201 [PMID:32659606] [10.1016/j.ejmech.2020.112478] |
| 565. Alkhaldi AAM,Al-Sanea MM,Nocentini A,Eldehna WM,Elsayed ZM,Bonardi A,Abo-Ashour MF,El-Damasy AK,Abdel-Maksoud MS,Al-Warhi T,Gratteri P,Abdel-Aziz HA,Supuran CT,El-Haggar R. (2020) 3-Methylthiazolo[3,2-a]benzimidazole-benzenesulfonamide conjugates as novel carbonic anhydrase inhibitors endowed with anticancer activity: Design, synthesis, biological and molecular modeling studies., 207 [PMID:32877804] [10.1016/j.ejmech.2020.112745] |
| 566. Abdelrahman MA,Ibrahim HS,Nocentini A,Eldehna WM,Bonardi A,Abdel-Aziz HA,Gratteri P,Abou-Seri SM,Supuran CT. (2021) Novel 3-substituted coumarins as selective human carbonic anhydrase IX and XII inhibitors: Synthesis, biological and molecular dynamics analysis., 209 [PMID:33038795] [10.1016/j.ejmech.2020.112897] |
| 567. Akgul O,Singh S,Andring JT,McKenna R,Selleri S,Carta F,Angeli A,Supuran CT. (2021) Handling drug-target selectivity: A study on ureido containing Carbonic Anhydrase inhibitors., 212 [PMID:33303238] [10.1016/j.ejmech.2020.113035] |
| 568. Swain B,Abhay null,Singh P,Angeli A,Aashritha K,Nagesh N,Supuran CT,Arifuddin M. (2021) 3-Functionalised benzenesulphonamide based 1,3,4-oxadiazoles as selective carbonic anhydrase XIII inhibitors: Design, synthesis and biological evaluation., 37 [PMID:33609663] [10.1016/j.bmcl.2021.127856] |
| 569. Nocentini A,Moi D,Deplano A,Osman SM,AlOthman ZA,Balboni G,Supuran CT,Onnis V. (2020) Sulfonamide/sulfamate switch with a series of piperazinylureido derivatives: Synthesis, kinetic and in silico evaluation as carbonic anhydrase isoforms I, II, IV, and IX inhibitors., 186 [PMID:31784185] [10.1016/j.ejmech.2019.111896] |
| 570. Swain B,Angeli A,Singh P,Supuran CT,Arifuddin M. (2020) New coumarin/sulfocoumarin linked phenylacrylamides as selective transmembrane carbonic anhydrase inhibitors: Synthesis and in-vitro biological evaluation., 28 (15): [PMID:32631564] [10.1016/j.bmc.2020.115586] |
| 571. Kaur J,Cao X,Abutaleb NS,Elkashif A,Graboski AL,Krabill AD,AbdelKhalek AH,An W,Bhardwaj A,Seleem MN,Flaherty DP. (2020) Optimization of Acetazolamide-Based Scaffold as Potent Inhibitors of Vancomycin-Resistant Enterococcus., 63 (17): [PMID:32787141] [10.1021/acs.jmedchem.0c00734] |
| 572. Bonardi A,Nocentini A,Cadoni R,Del Prete S,Dumy P,Capasso C,Gratteri P,Supuran CT,Winum JY. (2020) Benzoxaboroles: New Potent Inhibitors of the Carbonic Anhydrases of the Pathogenic Bacterium Vibrio cholerae., 11 (11): [PMID:33214840] [10.1021/acsmedchemlett.0c00403] |
| 573. Mancuso F,De Luca L,Angeli A,Berrino E,Del Prete S,Capasso C,Supuran CT,Gitto R. (2020) In Silico-Guided Identification of New Potent Inhibitors of Carbonic Anhydrases Expressed in Vibrio cholerae., 11 (11): [PMID:33214843] [10.1021/acsmedchemlett.0c00417] |
| 574. Bouzina A,Berredjem M,Nocentini A,Bua S,Bouaziz Z,Jose J,Le Borgne M,Marminon C,Gratteri P,Supuran CT. (2021) Ninhydrins inhibit carbonic anhydrases directly binding to the metal ion., 209 [PMID:33059188] [10.1016/j.ejmech.2020.112875] |
| 575. Mboge MY,Combs J,Singh S,Andring J,Wolff A,Tu C,Zhang Z,McKenna R,Frost SC. (2021) Inhibition of Carbonic Anhydrase Using SLC-149: Support for a Noncatalytic Function of CAIX in Breast Cancer., 64 (3.0): [PMID:33523653] [10.1021/acs.jmedchem.0c02077] |
| 576. Lenci E,Angeli A,Calugi L,Innocenti R,Carta F,Supuran CT,Trabocchi A. (2021) Multitargeting application of proline-derived peptidomimetics addressing cancer-related human matrix metalloproteinase 9 and carbonic anhydrase II., 214 [PMID:33581552] [10.1016/j.ejmech.2021.113260] |
| 577. Chandra KM,Goud NS,Arifuddin M,Alvala M,Alvala R,Angeli A,Supuran CT. (2021) Synthesis and biological evaluation of novel 4,7-disubstituted coumarins as selective tumor-associated carbonic anhydrase IX and XII inhibitors., 39 [PMID:33640442] [10.1016/j.bmcl.2021.127877] |
| 578. Petreni A,Bonardi A,Lomelino C,Osman SM,ALOthman ZA,Eldehna WM,El-Haggar R,McKenna R,Nocentini A,Supuran CT. (2020) Inclusion of a 5-fluorouracil moiety in nitrogenous bases derivatives as human carbonic anhydrase IX and XII inhibitors produced a targeted action against MDA-MB-231 and T47D breast cancer cells., 190 [PMID:32044580] [10.1016/j.ejmech.2020.112112] |
| 579. Elzahhar PA,Abd El Wahab SM,Elagawany M,Daabees H,Belal ASF,El-Yazbi AF,Eid AH,Alaaeddine R,Hegazy RR,Allam RM,Helmy MW,Bahaa Elgendy null,Angeli A,El-Hawash SA,Supuran CT. (2020) Expanding the anticancer potential of 1,2,3-triazoles via simultaneously targeting Cyclooxygenase-2, 15-lipoxygenase and tumor-associated carbonic anhydrases., 200 [PMID:32485532] [10.1016/j.ejmech.2020.112439] |
| 580. Bernhard Ellinger, Justus Dick, Vanessa Lage-Rupprecht, Bruce Schultz, Andrea Zaliani, Marcin Namysl, Stephan Gebel, Ole Pless, Jeanette Reinshagen, Christian Ebeling, Alexander Esser, Marc Jacobs, Carsten Claussen, and Martin Hofmann-Apitius. (2021) HDAC6 screening dataset using tau-based substrate in an enzymatic assay yields selective inhibitors and activators, [10.6019/CHEMBL4808148] |
| 581. Manzoor S, Petreni A, Raza MK, Supuran CT, Hoda N.. (2021) Novel triazole-sulfonamide bearing pyrimidine moieties with carbonic anhydrase inhibitory action: Design, synthesis, computational and enzyme inhibition studies., 48 [PMID:34237441] [10.1016/j.bmcl.2021.128249] |
| 582. Gumus A, Bozdag M, Angeli A, Peat TS, Carta F, Supuran CT, Selleri S.. (2021) Privileged scaffolds in medicinal chemistry: Studies on pyrazolo[1,5-a]pyrimidines on sulfonamide containing Carbonic Anhydrase inhibitors., 49 [PMID:34371130] [10.1016/j.bmcl.2021.128309] |
| 583. Elbadawi MM, Eldehna WM, Nocentini A, Abo-Ashour MF, Elkaeed EB, Abdelgawad MA, Alharbi KS, Abdel-Aziz HA, Supuran CT, Gratteri P, Al-Sanea MM.. (2021) Identification of N-phenyl-2-(phenylsulfonyl)acetamides/propanamides as new SLC-0111 analogues: Synthesis and evaluation of the carbonic anhydrase inhibitory activities., 218 [PMID:33773285] [10.1016/j.ejmech.2021.113360] |
| 584. Sharonova T, Paramonova P, Kalinin S, Bunev A, Gasanov RЕ, Nocentini A, Sharoyko V, Tennikova TB, Dar'in D, Supuran CT, Krasavin M.. (2021) Insertion of metal carbenes into the anilinic N-H bond of unprotected aminobenzenesulfonamides delivers low nanomolar inhibitors of human carbonic anhydrase IX and XII isoforms., 218 [PMID:33774343] [10.1016/j.ejmech.2021.113352] |
| 585. Angeli A, Pinteala M, Maier SS, Toti A, Di Cesare Mannelli L, Ghelardini C, Selleri S, Carta F, Supuran CT.. (2021) Tellurides bearing benzensulfonamide as carbonic anhydrase inhibitors with potent antitumor activity., 45 [PMID:34052322] [10.1016/j.bmcl.2021.128147] |
| 586. Mancuso F, Di Fiore A, De Luca L, Angeli A, De Simone G, Supuran CT, Gitto R.. (2021) Design, synthesis and biochemical evaluation of novel carbonic anhydrase inhibitors triggered by structural knowledge on hCA VII., 44 [PMID:34216985] [10.1016/j.bmc.2021.116279] |
| 587. Patel OPS, Jesumoroti OJ, Legoabe LJ, Beteck RM.. (2021) Metronidazole-conjugates: A comprehensive review of recent developments towards synthesis and medicinal perspective., 210 [PMID:33234343] [10.1016/j.ejmech.2020.112994] |
| 588. Zhang B, Liu Z, Xia S, Liu Q, Gou S.. (2021) Design, synthesis and biological evaluation of sulfamoylphenyl-quinazoline derivatives as potential EGFR/CAIX dual inhibitors., 216 [PMID:33640672] [10.1016/j.ejmech.2021.113300] |
| 589. Shaldam M, Eldehna WM, Nocentini A, Elsayed ZM, Ibrahim TM, Salem R, El-Domany RA, Capasso C, Abdel-Aziz HA, Supuran CT.. (2021) Development of novel benzofuran-based SLC-0111 analogs as selective cancer-associated carbonic anhydrase isoform IX inhibitors., 216 [PMID:33667848] [10.1016/j.ejmech.2021.113283] |
| 590. Yamali C, Sakagami H, Uesawa Y, Kurosaki K, Satoh K, Masuda Y, Yokose S, Ece A, Bua S, Angeli A, Supuran CT, Gul HI.. (2021) Comprehensive study on potent and selective carbonic anhydrase inhibitors: Synthesis, bioactivities and molecular modelling studies of 4-(3-(2-arylidenehydrazine-1-carbonyl)-5-(thiophen-2-yl)-1H-pyrazole-1-yl) benzenesulfonamides., 217 [PMID:33744685] [10.1016/j.ejmech.2021.113351] |
| 591. Umm-E-Farwa, Ullah S, Khan MA, Zafar H, Atia-Tul-Wahab, Younus M, Choudhary MI, Basha FZ.. (2021) Dibenzazepine-linked isoxazoles: New and potent class of α-glucosidase inhibitors., 40 [PMID:33766763] [10.1016/j.bmcl.2021.127979] |
| 592. Akgul O, Angeli A, Selleri S, Capasso C, Supuran CT, Carta F.. (2021) Taurultams incorporating arylsulfonamide: First in vitro inhibition studies of α-, β- and γ-class Carbonic Anhydrases from Vibrio cholerae and Burkholderia pseudomallei., 219 [PMID:33866238] [10.1016/j.ejmech.2021.113444] |
| 593. Buabeng ER, Henary M.. (2021) Developments of small molecules as inhibitors for carbonic anhydrase isoforms., 39 [PMID:33905966] [10.1016/j.bmc.2021.116140] |
| 594. Mishra CB, Kumari S, Angeli A, Bua S, Mongre RK, Tiwari M, Supuran CT.. (2021) Discovery of Potent Carbonic Anhydrase Inhibitors as Effective Anticonvulsant Agents: Drug Design, Synthesis, and In Vitro and In Vivo Investigations., 64 (6.0): [PMID:33721499] [10.1021/acs.jmedchem.0c01889] |
| 595. Dar'in D, Kantin G, Kalinin S, Sharonova T, Bunev A, Ostapenko GI, Nocentini A, Sharoyko V, Supuran CT, Krasavin M.. (2021) Investigation of 3-sulfamoyl coumarins against cancer-related IX and XII isoforms of human carbonic anhydrase as well as cancer cells leads to the discovery of 2-oxo-2H-benzo[h]chromene-3-sulfonamide - A new caspase-activating proapoptotic agent., 222 [PMID:34147910] [10.1016/j.ejmech.2021.113589] |
| 596. Salerno S, Amendola G, Angeli A, Baglini E, Barresi E, Marini AM, Ravichandran R, Viviano M, Castellano S, Novellino E, Da Settimo F, Supuran CT, Cosconati S, Taliani S.. (2021) Inhibition studies on carbonic anhydrase isoforms I, II, IV and IX with N-arylsubstituted secondary sulfonamides featuring a bicyclic tetrahydroindazole scaffold., 220 [PMID:33975138] [10.1016/j.ejmech.2021.113490] |
| 597. Tanini D, Carradori S, Capperucci A, Lupori L, Zara S, Ferraroni M, Ghelardini C, Mannelli L, Micheli L, Lucarini E, Carta F, Angeli A, Supuran CT.. (2021) Chalcogenides-incorporating carbonic anhydrase inhibitors concomitantly reverted oxaliplatin-induced neuropathy and enhanced antiproliferative action., 225 [PMID:34507012] [10.1016/j.ejmech.2021.113793] |
| 598. Eldeeb AH, Abo-Ashour MF, Angeli A, Bonardi A, Lasheen DS, Elrazaz EZ, Nocentini A, Gratteri P, Abdel-Aziz HA, Supuran CT.. (2021) Novel benzenesulfonamides aryl and arylsulfone conjugates adopting tail/dual tail approaches: Synthesis, carbonic anhydrase inhibitory activity and molecular modeling studies., 221 [PMID:33965860] [10.1016/j.ejmech.2021.113486] |
| 599. Elimam DM, Elgazar AA, Bonardi A, Abdelfadil M, Nocentini A, El-Domany RA, Abdel-Aziz HA, Badria FA, Supuran CT, Eldehna WM.. (2021) Natural inspired piperine-based sulfonamides and carboxylic acids as carbonic anhydrase inhibitors: Design, synthesis and biological evaluation., 225 [PMID:34482273] [10.1016/j.ejmech.2021.113800] |
| 600. Plyasova AA, Berrino E, Khan II, Veselovsky AV, Pokrovsky VS, Angeli A, Ferraroni M, Supuran CT, Pokrovskaya MV, Alexandrova SS, Gladilina YA, Sokolov NN, Hilal A, Carta F, Zhdanov DD.. (2021) Mechanisms of the Antiproliferative and Antitumor Activity of Novel Telomerase-Carbonic Anhydrase Dual-Hybrid Inhibitors., 64 (15.0): [PMID:34283610] [10.1021/acs.jmedchem.1c00756] |
| 601. Hou Z, Cai Q, Cheng MS.. (2021) Novel carbohydrate-based sulfonamide derivatives as selective carbonic anhydrase II inhibitors: Synthesis, biological and molecular docking analysis., 51 [PMID:34324968] [10.1016/j.bmcl.2021.128291] |
| 602. Wang X, Feng YL, Zhao XY, An R, Cao C, Guo MB, Zhang R, Wang YX, Hou Z, Guo C.. (2021) Discovery of novel aminosaccharide-based sulfonamide derivatives as potential carbonic anhydrase II inhibitors., 53 [PMID:34728369] [10.1016/j.bmcl.2021.128420] |
| 603. Angeli A, Ferraroni M, Da'dara AA, Selleri S, Pinteala M, Carta F, Skelly PJ, Supuran CT.. (2021) Structural Insights into Schistosoma mansoni Carbonic Anhydrase (SmCA) Inhibition by Selenoureido-Substituted Benzenesulfonamides., 64 (14.0): [PMID:34232641] [10.1021/acs.jmedchem.1c00840] |
| 604. Abdel-Mohsen HT, El Kerdawy AM, Omar MA, Petreni A, Allam RM, El Diwani HI, Supuran CT.. (2022) Application of the dual-tail approach for the design and synthesis of novel Thiopyrimidine-Benzenesulfonamide hybrids as selective carbonic anhydrase inhibitors., 228 [PMID:34847409] [10.1016/j.ejmech.2021.114004] |
| 605. Elimam DM, Eldehna WM, Salem R, Bonardi A, Nocentini A, Al-Rashood ST, Elaasser MM, Gratteri P, Supuran CT, Allam HA.. (2022) Natural inspired ligustrazine-based SLC-0111 analogues as novel carbonic anhydrase inhibitors., 228 [PMID:34871842] [10.1016/j.ejmech.2021.114008] |
| 606. Chiaramonte N, Angeli A, Sgambellone S, Bonardi A, Nocentini A, Bartolucci G, Braconi L, Dei S, Lucarini L, Teodori E, Gratteri P, Wünsch B, Supuran CT, Romanelli MN.. (2022) 2-(2-Hydroxyethyl)piperazine derivatives as potent human carbonic anhydrase inhibitors: Synthesis, enzyme inhibition, computational studies and antiglaucoma activity., 228 [PMID:34920169] [10.1016/j.ejmech.2021.114026] |
| 607. Vannozzi G, Vullo D, Angeli A, Ferraroni M, Combs J, Lomelino C, Andring J, Mckenna R, Bartolucci G, Pallecchi M, Lucarini L, Sgambellone S, Masini E, Carta F, Supuran CT.. (2022) One-Pot Procedure for the Synthesis of Asymmetric Substituted Ureido Benzene Sulfonamides as Effective Inhibitors of Carbonic Anhydrase Enzymes., 65 (1.0): [PMID:34958217] [10.1021/acs.jmedchem.1c01906] |
| 608. Krymov SK, Scherbakov AM, Salnikova DI, Sorokin DV, Dezhenkova LG, Ivanov IV, Vullo D, De Luca V, Capasso C, Supuran CT, Shchekotikhin AE.. (2022) Synthesis, biological evaluation, and in silico studies of potential activators of apoptosis and carbonic anhydrase inhibitors on isatin-5-sulfonamide scaffold., 228 [PMID:34902732] [10.1016/j.ejmech.2021.113997] |
| 609. Kumar S, Rulhania S, Jaswal S, Monga V.. (2021) Recent advances in the medicinal chemistry of carbonic anhydrase inhibitors., 209 [PMID:33121862] [10.1016/j.ejmech.2020.112923] |
| 610. Bonardi A, Micheli L, Di Cesare Mannelli L, Ghelardini C, Gratteri P, Nocentini A, Supuran CT.. (2022) Development of Hydrogen Sulfide-Releasing Carbonic Anhydrases IX- and XII-Selective Inhibitors with Enhanced Antihyperalgesic Action in a Rat Model of Arthritis., 65 (19.0): [PMID:36121705] [10.1021/acs.jmedchem.2c00982] |
| 611. Zhou W, Wang C, Liu Z, Gou S.. (2022) Hypoxia-Activated Prodrugs with Dual COX-2/CA Inhibitory Effects on Attenuating Cardiac Inflammation under Hypoxia., 65 (19.0): [PMID:36170566] [10.1021/acs.jmedchem.2c01355] |
| 612. Artasensi A, Angeli A, Lammi C, Bollati C, Gervasoni S, Baron G, Matucci R, Supuran CT, Vistoli G, Fumagalli L.. (2022) Discovery of a Potent and Highly Selective Dipeptidyl Peptidase IV and Carbonic Anhydrase Inhibitor as "Antidiabesity" Agents Based on Repurposing and Morphing of WB-4101., 65 (20.0): [PMID:36201615] [10.1021/acs.jmedchem.2c01192] |
| 613. Elbadawi MM, Eldehna WM, Nocentini A, Somaa WR, Al-Rashood ST, Elkaeed EB, El Hassab MA, Abdel-Aziz HA, Supuran CT, Fares M.. (2022) Development of 4-((3-oxo-3-phenylpropyl)amino)benzenesulfonamide derivatives utilizing tail/dual-tail approaches as novel carbonic anhydrase inhibitors., 238 [PMID:35551035] [10.1016/j.ejmech.2022.114412] |
| 614. Fantacuzzi M, Amoroso R, Carradori S, De Filippis B.. (2022) Resveratrol-based compounds and neurodegeneration: Recent insight in multitarget therapy., 233 [PMID:35276424] [10.1016/j.ejmech.2022.114242] |
| 615. Singh P, Sridhar Goud N, Swain B, Kumar Sahoo S, Choli A, Angeli A, Singh Kushwah B, Madhavi Yaddanapudi V, Supuran CT, Arifuddin M.. (2022) Synthesis of a new series of quinoline/pyridine indole-3-sulfonamide hybrids as selective carbonic anhydrase IX inhibitors., 70 [PMID:35605838] [10.1016/j.bmcl.2022.128809] |
| 616. Huwaimel BI, Jonnalagadda S, Jonnalagadda S, Zahra FT, Nocentini A, Supuran CT, Mikelis CM, Trippier PC.. (2022) Chlorinated benzothiadiazines inhibit angiogenesis through suppression of VEGFR2 phosphorylation., 67 [PMID:35635929] [10.1016/j.bmc.2022.116805] |
| 617. Bahadur A, Iqbal S, Muneer S, Alsaab HO, Awwad NS, Ibrahium HA.. (2022) Synthesis, carbonic anhydrase enzyme inhibition evaluations, and anticancer studies of sulfonamide based thiadiazole derivatives., 57 [PMID:34965467] [10.1016/j.bmcl.2021.128520] |
| 618. Erigür EC, Altuğ C, Angeli A, Supuran CT.. (2022) Design, synthesis and human carbonic anhydrase I, II, IX and XII inhibitory properties of 1,3-thiazole sulfonamides., 59 [PMID:35066141] [10.1016/j.bmcl.2022.128581] |
| 619. Swain B, Sahoo SK, Singh P, Angeli A, Yaddanapudi VM, Supuran CT, Arifuddin M.. (2022) Exploration of 2-phenylquinoline-4-carboxamide linked benzene sulfonamide derivatives as isoform selective inhibitors of transmembrane human carbonic anhydrases., 234 [PMID:35305463] [10.1016/j.ejmech.2022.114247] |
| 620. Akgül Ö, Lucarini E, Mannelli LDC, Ghelardini C, D'Ambrosio K, Buonanno M, Monti SM, De Simone G, Angeli A, Supuran CT, Carta F.. (2022) Sultam based Carbonic Anhydrase VII inhibitors for the management of neuropathic pain., 227 [PMID:34731762] [10.1016/j.ejmech.2021.113956] |
| 621. Tawfik HO, Petreni A, Supuran CT, El-Hamamsy MH.. (2022) Discovery of new carbonic anhydrase IX inhibitors as anticancer agents by toning the hydrophobic and hydrophilic rims of the active site to encounter the dual-tail approach., 232 [PMID:35182815] [10.1016/j.ejmech.2022.114190] |
| 622. Braconi L, Teodori E, Riganti C, Coronnello M, Nocentini A, Bartolucci G, Pallecchi M, Contino M, Manetti D, Romanelli MN, Supuran CT, Dei S.. (2022) New Dual P-Glycoprotein (P-gp) and Human Carbonic Anhydrase XII (hCA XII) Inhibitors as Multidrug Resistance (MDR) Reversers in Cancer Cells., 65 (21.0): [PMID:36269278] [10.1021/acs.jmedchem.2c01175] |
| 623. Marapaka AK, Nocentini A, Youse MS, An W, Holly KJ, Das C, Yadav R, Seleem MN, Supuran CT, Flaherty DP.. (2023) Structural Characterization of Thiadiazolesulfonamide Inhibitors Bound to Neisseria gonorrhoeae α-Carbonic Anhydrase., 14 (1.0): [PMID:36655133] [10.1021/acsmedchemlett.2c00471] |
| 624. Kakakhan C, Türkeş C, Güleç Ö, Demir Y, Arslan M, Özkemahlı G, Beydemir Ş.. (2023) Exploration of 1,2,3-triazole linked benzenesulfonamide derivatives as isoform selective inhibitors of human carbonic anhydrase., 77 [PMID:36463726] [10.1016/j.bmc.2022.117111] |
| 625. Wan Y, Fang G, Chen H, Deng X, Tang Z.. (2021) Sulfonamide derivatives as potential anti-cancer agents and their SARs elucidation., 226 [PMID:34530384] [10.1016/j.ejmech.2021.113837] |
| 626. Ghatpande NG, Jadhav JS, Kaproormath RV, Soliman ME, Shaikh MM.. (2020) A brief overview on recent advances in spiro[chromane-2,4'-piperidine]-4(3H)-one-functionalized compounds in medicinal chemistry research., 28 (23.0): [PMID:33069128] [10.1016/j.bmc.2020.115813] |
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