ID: ALA2068507

Max Phase: Preclinical

Molecular Formula: C21H20Cl2N6O6Pt

Molecular Weight: 718.41

Molecule Type: Small molecule

Molecule Features

Natural Product: No

Oral: No

Chemical Probe: No

Parenteral: No

Molecule Type: Small molecule

Topical: No

First In Class: No

Black Box: No

Chirality: No

Availability: No

Prodrug: No

Properties

Molecular Weight: 718.41

Molecular Weight (Monoisotopic): 717.0469

AlogP:

#Rotatable Bonds:

Polar Surface Area:

Molecular Species:

HBA:

HBD:

#RO5 Violations:

HBA (Lipinski):

HBD (Lipinski):

#RO5 Violations (Lipinski):

CX Acidic pKa:

CX Basic pKa:

CX LogP:

CX LogD:

Aromatic Rings:

Heavy Atoms:

QED Weighted:

Np Likeness Score:

References

1. Millet R, Urig S, Jacob J, Amtmann E, Moulinoux JP, Gromer S, Becker K, Davioud-Charvet E..  (2005)  Synthesis of 5-nitro-2-furancarbohydrazides and their cis-diamminedichloroplatinum complexes as bitopic and irreversible human thioredoxin reductase inhibitors.,  48  (22): [PMID:16250662] [10.1021/jm050256l]

Source

Source(1):

• Scientific Literature