Diethyl meso-4,5-Diaminosuberate{7,12-bis[1-(1,4,7,10-tetraoxaundecyl)ethyl]-3,8,13,17-tetramethylporphyrin-2,18-dipropionato}platinum (II)

ID: ALA2068552

Max Phase: Preclinical

Molecular Formula: C60H86N6O16Pt

Molecular Weight: 1342.45

Molecule Type: Unknown

This compound is available for customization.

Associated Items:

Associated Targets(Human)

TCC-SUP (149 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Molecule Features

Natural Product: NoOral: NoChemical Probe: NoParenteral: No
Molecule Type: UnknownTopical: NoFirst In Class: NoBlack Box: No
Chirality: NoAvailability: NoProdrug: No

Drug Indications

MESH IDMESH Heading EFO IDsEFO TermsMax Phase for IndicationReferences

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Biocomponents

Calculated Properties

Molecular Weight: 1342.45Molecular Weight (Monoisotopic): 1341.5748AlogP: #Rotatable Bonds:
Polar Surface Area: Molecular Species: HBA: HBD:
#RO5 Violations: HBA (Lipinski): HBD (Lipinski): #RO5 Violations (Lipinski):
CX Acidic pKa: CX Basic pKa: CX LogP: CX LogD:
Aromatic Rings: Heavy Atoms: QED Weighted: Np Likeness Score:

References

1. Lottner C, Bart KC, Bernhardt G, Brunner H..  (2002)  Hematoporphyrin-derived soluble porphyrin-platinum conjugates with combined cytotoxic and phototoxic antitumor activity.,  45  (10): [PMID:11985474] [10.1021/jm0110688]

Source