| 1. PubChem BioAssay data set, |
| 2. PubChem BioAssay data set, |
| 3. Miyazaki M, Kawato H, Naito H, Ikeda M, Miyazaki M, Kitagawa M, Seki T, Fukutake S, Aonuma M, Soga T.. (2012) Discovery of novel dihydroimidazothiazole derivatives as p53-MDM2 protein-protein interaction inhibitors: synthesis, biological evaluation and structure-activity relationships., 22 (20): [PMID:22995624] [10.1016/j.bmcl.2012.08.086] |
| 4. Wang W, Zhu X, Hong X, Zheng L, Zhu H, Hu Y. (2013) Identification of novel inhibitors of p53MDM2 interaction facilitated by pharmacophore-based virtual screening combining molecular docking strategy, 4 (2): [10.1039/C2MD20208E] |
| 5. Daniele S, La Pietra V, Barresi E, Di Maro S, Da Pozzo E, Robello M, La Motta C, Cosconati S, Taliani S, Marinelli L, Novellino E, Martini C, Da Settimo F.. (2016) Lead Optimization of 2-Phenylindolylglyoxylyldipeptide Murine Double Minute (MDM)2/Translocator Protein (TSPO) Dual Inhibitors for the Treatment of Gliomas., 59 (10): [PMID:27050782] [10.1021/acs.jmedchem.5b01767] |
| 6. Surmiak E, Neochoritis CG, Musielak B, Twarda-Clapa A, Kurpiewska K, Dubin G, Camacho C, Holak TA, Dömling A.. (2017) Rational design and synthesis of 1,5-disubstituted tetrazoles as potent inhibitors of the MDM2-p53 interaction., 126 [PMID:27907876] [10.1016/j.ejmech.2016.11.029] |
| 7. Bernhard Ellinger, Denisa Bojkova, Andrea Zaliani, Jindrich Cinatl, Carsten Claussen, Sandra Westhaus, Jeanette Reinshagen, Maria Kuzikov, Markus Wolf, Gerd Geisslinger, Philip Gribbon, Sandra Ciesek. (2020) Identification of inhibitors of SARS-CoV-2 in-vitro cellular toxicity in human (Caco-2) cells using a large scale drug repurposing collection, [10.21203/rs.3.rs-23951/v1] |
| 8. Sang P, Shi Y, Lu J, Chen L, Yang L, Borcherds W, Abdulkadir S, Li Q, Daughdrill G, Chen J, Cai J.. (2020) α-Helix-Mimicking Sulfono-γ-AApeptide Inhibitors for p53-MDM2/MDMX Protein-Protein Interactions., 63 (3): [PMID:31971801] [10.1021/acs.jmedchem.9b00993] |
| 9. Liu Y, Wang X, Wang G, Yang Y, Yuan Y, Ouyang L.. (2019) The past, present and future of potential small-molecule drugs targeting p53-MDM2/MDMX for cancer therapy., 176 [PMID:31100649] [10.1016/j.ejmech.2019.05.018] |
| 10. Maria Kuzikov, Elisa Costanzi, Jeanette Reinshagen, Francesca Esposito, Laura Vangeel, Markus Wolf, Bernhard Ellinger, Carsten Claussen, Gerd Geisslinger, Angela Corona, Daniela Iaconis, Carmine Talarico, Candida Manelfi, Rolando Cannalire, Giulia Rossetti, Jonas Gossen, Simone Albani, Francesco Musiani, Katja Herzog, Yang Ye, Barbara Giabbai, Nicola Demitri, Dirk Jochmans, Steven De Jonghe, Jasper Rymenants, Vincenzo Summa, Enzo Tramontano, Andrea R. Beccari, Pieter Leyssen, Paola Storici, Johan Neyts, Philip Gribbon, and Andrea Zaliani. (2020) Identification of inhibitors of SARS-Cov2 M-Pro enzymatic activity using a small molecule repurposing screen, [10.6019/CHEMBL4495564] |
| 11. Andrea Zaliani, Laura Vangeel, Jeanette Reinshagen, Daniela Iaconis, Maria Kuzikov, Oliver Keminer, Markus Wolf, Bernhard Ellinger, Francesca Esposito, Angela Corona, Enzo Tramontano, Candida Manelfi, Katja Herzog, Dirk Jochmans, Steven De Jonghe, Winston Chiu, Thibault Francken, Joost Schepers, Caroline Collard, Kayvan Abbasi, Carsten Claussen , Vincenzo Summa, Andrea R. Beccari, Johan Neyts, Philip Gribbon and Pieter Leyssen. (2020) Cytopathic SARS-Cov2 screening on VERO-E6 cells in a large repurposing effort, [10.6019/CHEMBL4495565] |
| 12. Bernhard Ellinger, Justus Dick, Vanessa Lage-Rupprecht, Bruce Schultz, Andrea Zaliani, Marcin Namysl, Stephan Gebel, Ole Pless, Jeanette Reinshagen, Christian Ebeling, Alexander Esser, Marc Jacobs, Carsten Claussen, and Martin Hofmann-Apitius. (2021) HDAC6 screening dataset using tau-based substrate in an enzymatic assay yields selective inhibitors and activators, [10.6019/CHEMBL4808148] |
| 13. Liu SJ, Zhao Q, Peng C, Mao Q, Wu F, Zhang FH, Feng QS, He G, Han B.. (2021) Design, synthesis, and biological evaluation of nitroisoxazole-containing spiro[pyrrolidin-oxindole] derivatives as novel glutathione peroxidase 4/mouse double minute 2 dual inhibitors that inhibit breast adenocarcinoma cell proliferation., 217 [PMID:33725632] [10.1016/j.ejmech.2021.113359] |
| 14. Chan AM, Goodis CC, Pommier EG, Fletcher S.. (2022) Recent applications of covalent chemistries in protein-protein interaction inhibitors., 13 (8.0): [PMID:36092144] [10.1039/d2md00112h] |
| 15. Pillaiyar T, Meenakshisundaram S, Manickam M, Sankaranarayanan M.. (2020) A medicinal chemistry perspective of drug repositioning: Recent advances and challenges in drug discovery., 195 [PMID:32283298] [10.1016/j.ejmech.2020.112275] |
| 16. Zhang J, Gao Y, Zhang Z, Zhao J, Jia W, Xia C, Wang F, Liu T.. (2022) Multi-therapies Based on PARP Inhibition: Potential Therapeutic Approaches for Cancer Treatment., 65 (24.0): [PMID:36512711] [10.1021/acs.jmedchem.2c01352] |
