2-(4-(diethoxyphosphoryloxy)phenoxy)-N'-(2-oxoindolin-3-ylidene)acetohydrazonic(diethyl phosphoric)anhydride

ID: ALA2228709

PubChem CID: 136249226

Max Phase: Preclinical

Molecular Formula: C24H31N3O10P2

Molecular Weight: 583.47

Molecule Type: Small molecule

Names and Identifiers

Canonical SMILES:  CCOP(=O)(OCC)O/C(COc1ccc(OP(=O)(OCC)OCC)cc1)=N\N=C1/C(=O)Nc2ccccc21

Standard InChI:  InChI=1S/C24H31N3O10P2/c1-5-32-38(29,33-6-2)36-19-15-13-18(14-16-19)31-17-22(37-39(30,34-7-3)35-8-4)26-27-23-20-11-9-10-12-21(20)25-24(23)28/h9-16H,5-8,17H2,1-4H3,(H,25,27,28)/b26-22-

Standard InChI Key:  JLBXHAWBCGKUQS-ROMGYVFFSA-N

Molfile:  

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M  END

Alternative Forms

1. Parent:

   

   ALA2228709

   ---

Molecule Features

Natural Product: No

Oral: No

Chemical Probe: No

Parenteral: No

Molecule Type: Small molecule

Topical: No

First In Class: No

Black Box: No

Chirality: No

Availability: No

Prodrug: No

Calculated Properties

Molecular Weight: 583.47

Molecular Weight (Monoisotopic): 583.1485

AlogP: 5.58

#Rotatable Bonds: 15

Polar Surface Area: 152.57

Molecular Species: NEUTRAL

HBA: 12

HBD: 1

#RO5 Violations: 3

HBA (Lipinski): 13

HBD (Lipinski): 1

#RO5 Violations (Lipinski): 3

CX Acidic pKa: 9.85

CX Basic pKa: ┄

CX LogP: 3.64

CX LogD: 3.64

Aromatic Rings: 2

Heavy Atoms: 39

QED Weighted: 0.12

Np Likeness Score: -0.26

References

1. Pandey VK, Dwivedi A, Pandey OP, Sengupta SK..  (2008)  Organophosphorus derivatives containing isatin-3-hydrazones as chemotherapeutants against fungal pathogens of sugarcane.,  56  (22): [PMID:18954075] [10.1021/jf801975z]

Source

Source(1):

• Scientific Literature