1. Parker MA, Marona-Lewicka D, Kurrasch D, Shulgin AT, Nichols DE.. (1998) Synthesis and pharmacological evaluation of ring-methylated derivatives of 3,4-(methylenedioxy)amphetamine (MDA)., 41 (6): [PMID:9526575] [10.1021/jm9705925] |
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3. Blair JB, Marona-Lewicka D, Kanthasamy A, Lucaites VL, Nelson DL, Nichols DE.. (1999) Thieno[3,2-b]- and thieno[2,3-b]pyrrole bioisosteric analogues of the hallucinogen and serotonin agonist N,N-dimethyltryptamine., 42 (6): [PMID:10090793] [10.1021/jm980692q] |
4. Nichols DE, Jadhav KP, Oberlender RA, Zabik JE, Bossart JF, Hamada A, Miller DD.. (1984) Synthesis and evaluation of substituted 2-phenylcyclobutylamines as analogues of hallucinogenic phenethylamines: lack of LSD-like biological activity., 27 (9): [PMID:6471065] [10.1021/jm00375a004] |
5. Hoffman AJ, Nichols DE.. (1985) Synthesis and LSD-like discriminative stimulus properties in a series of N(6)-alkyl norlysergic acid N,N-diethylamide derivatives., 28 (9): [PMID:4032428] [10.1021/jm00147a022] |
6. Andrews PR, Craik DJ, Martin JL.. (1984) Functional group contributions to drug-receptor interactions., 27 (12): [PMID:6094812] [10.1021/jm00378a021] |
7. Johnson MP, Frescas SP, Oberlender R, Nichols DE.. (1991) Synthesis and pharmacological examination of 1-(3-methoxy-4-methylphenyl)-2-aminopropane and 5-methoxy-6-methyl-2-aminoindan: similarities to 3,4-(methylenedioxy)methamphetamine (MDMA)., 34 (5): [PMID:1674539] [10.1021/jm00109a020] |
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9. Oberlender R, Pfaff RC, Johnson MP, Huang XM, Nichols DE.. (1992) Stereoselective LSD-like activity in d-lysergic acid amides of (R)- and (S)-2-aminobutane., 35 (2): [PMID:1732537] [10.1021/jm00080a001] |
10. Monte AP, Marona-Lewicka D, Lewis MM, Mailman RB, Wainscott DB, Nelson DL, Nichols DE.. (1998) Substituted naphthofurans as hallucinogenic phenethylamine-ergoline hybrid molecules with unexpected muscarinic antagonist activity., 41 (12): [PMID:9622555] [10.1021/jm980076u] |
11. Glennon RA.. (2003) Higher-end serotonin receptors: 5-HT(5), 5-HT(6), and 5-HT(7)., 46 (14): [PMID:12825922] [10.1021/jm030030n] |
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13. Chambers JJ, Parrish JC, Jensen NH, Kurrasch-Orbaugh DM, Marona-Lewicka D, Nichols DE.. (2003) Synthesis and pharmacological characterization of a series of geometrically constrained 5-HT(2A/2C) receptor ligands., 46 (16): [PMID:12877591] [10.1021/jm030064v] |
14. Oberlender R, Ramachandran PV, Johnson MP, Huang X, Nichols DE.. (1995) Effect of a chiral 4-alkyl substituent in hallucinogenic amphetamines., 38 (18): [PMID:7658446] [10.1021/jm00018a019] |
15. Gerasimov M, Marona-Lewicka D, Kurrasch-Orbaugh DM, Qandil AM, Nichols DE.. (1999) Further studies on oxygenated tryptamines with LSD-like activity incorporating a chiral pyrrolidine moiety into the side chain., 42 (20): [PMID:10514296] [10.1021/jm990325u] |
16. Nichols DE, Frescas S, Marona-Lewicka D, Kurrasch-Orbaugh DM.. (2002) Lysergamides of isomeric 2,4-dimethylazetidines map the binding orientation of the diethylamide moiety in the potent hallucinogenic agent N,N-diethyllysergamide (LSD)., 45 (19): [PMID:12213075] [10.1021/jm020153s] |
17. Blair JB, Kurrasch-Orbaugh D, Marona-Lewicka D, Cumbay MG, Watts VJ, Barker EL, Nichols DE.. (2000) Effect of ring fluorination on the pharmacology of hallucinogenic tryptamines., 43 (24): [PMID:11101361] [10.1021/jm000339w] |
18. Arvidsson LE, Hacksell U, Johansson AM, Nilsson JL, Lindberg P, Sanchez D, Wikström H, Svensson K, Hjorth S, Carlsson A.. (1984) 8-Hydroxy-2-(alkylamino)tetralins and related compounds as central 5-hydroxytryptamine receptor agonists., 27 (1): [PMID:6418888] [10.1021/jm00367a009] |
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20. Parker MA, Marona-Lewicka D, Lucaites VL, Nelson DL, Nichols DE.. (1998) A novel (benzodifuranyl)aminoalkane with extremely potent activity at the 5-HT2A receptor., 41 (26): [PMID:9857084] [10.1021/jm9803525] |
21. Vermeulen ES, Schmidt AW, Sprouse JS, Wikström HV, Grol CJ.. (2003) Characterization of the 5-HT(7) receptor. Determination of the pharmacophore for 5-HT(7) receptor agonism and CoMFA-based modeling of the agonist binding site., 46 (25): [PMID:14640545] [10.1021/jm030826m] |
22. Nichols DE, Brewster WK, Johnson MP, Oberlender R, Riggs RM.. (1990) Nonneurotoxic tetralin and indan analogues of 3,4-(methylenedioxy)amphetamine (MDA)., 33 (2): [PMID:1967651] [10.1021/jm00164a037] |
23. Glennon RA, Raghupathi R, Bartyzel P, Teitler M, Leonhardt S.. (1992) Binding of phenylalkylamine derivatives at 5-HT1C and 5-HT2 serotonin receptors: evidence for a lack of selectivity., 35 (4): [PMID:1542100] [10.1021/jm00082a014] |
24. Oberlender RA, Kothari PJ, Nichols DE, Zabik JE.. (1984) Substituent branching in phenethylamine-type hallucinogens: a comparison of 1-[2,5-dimethoxy-4-(2-butyl)phenyl]-2-aminopropane and 1-[2,5-dimethoxy-4-(2-methylpropyl)phenyl]-2-aminopropane., 27 (6): [PMID:6737421] [10.1021/jm00372a015] |
25. Laban U, Kurrasch-Orbaugh D, Marona-Lewicka D, Nichols DE.. (2001) A novel fluorinated tryptamine with highly potent serotonin 5-HT1A receptor agonist properties., 11 (6): [PMID:11277522] [10.1016/s0960-894x(01)00062-2] |
26. Kothari PJ, Hathaway BA, Nichols DE, Yim GK.. (1981) Synthesis and serotonin-like activity of 2-amino-5,8-dimethoxy-6-methyl-1,2-dihydronaphthalene., 24 (7): [PMID:7277398] [10.1021/jm00139a022] |
27. Monte AP, Marona-Lewicka D, Kanthasamy A, Sanders-Bush E, Nichols DE.. (1995) Stereoselective LSD-like activity in a series of d-lysergic acid amides of (R)- and (S)-2-aminoalkanes., 38 (6): [PMID:7699712] [10.1021/jm00006a015] |
28. McLean TH, Chambers JJ, Parrish JC, Braden MR, Marona-Lewicka D, Kurrasch-Orbaugh D, Nichols DE.. (2006) C-(4,5,6-trimethoxyindan-1-yl)methanamine: a mescaline analogue designed using a homology model of the 5-HT2A receptor., 49 (14): [PMID:16821786] [10.1021/jm060272y] |
29. Sweetnam PM, Caldwell L, Lancaster J, Bauer C, McMillan B, Kinnier WJ, Price CH.. (1993) The role of receptor binding in drug discovery., 56 (4): [PMID:8496700] [10.1021/np50094a001] |
30. Nichols DE, Frescas SP, Chemel BR, Rehder KS, Zhong D, Lewin AH.. (2008) High specific activity tritium-labeled N-(2-methoxybenzyl)-2,5-dimethoxy-4-iodophenethylamine (INBMeO): a high-affinity 5-HT2A receptor-selective agonist radioligand., 16 (11): [PMID:18468904] [10.1016/j.bmc.2008.04.050] |
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34. USP Dictionary of USAN and International Names (2010 edition) and USAN registrations 2007-date, |
35. PubChem BioAssay data set, |
36. Noorizadeh H, Noorizadeh M, Farmany A. (2012) Advanced QSRR models of toxicological screening of basic drugs in whole blood by UPLC-TOFMS, 21 (12): [10.1007/s00044-012-9977-1] |
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38. PubChem BioAssay data set, |
39. Jacob P, Anderson G, Meshul CK, Shulgin AT, Castagnoli N.. (1977) Monomethylthio analogues of 1-(2,4,5-trimethoxyphenyl)-2-aminopropane., 20 (10): [PMID:903913] [10.1021/jm00220a001] |
40. Unpublished dataset, |
41. Poulie CBM, Pottie E, Simon IA, Harpsøe K, D'Andrea L, Komarov IV, Gloriam DE, Jensen AA, Stove CP, Kristensen JL.. (2022) Discovery of β-Arrestin-Biased 25CN-NBOH-Derived 5-HT2A Receptor Agonists., 65 (18.0): [PMID:36099411] [10.1021/acs.jmedchem.2c00702] |