| 1. Ghose AK, Crippen GM.. (1983) Combined distance geometry analysis of dihydrofolate reductase inhibition by quinazolines and triazines., 26 (7): [PMID:6864738] [10.1021/jm00361a012] |
| 2. Booth RG, Selassie CD, Hansch C, Santi DV.. (1987) Quantitative structure-activity relationship of triazine-antifolate inhibition of Leishmania dihydrofolate reductase and cell growth., 30 (7): [PMID:3599028] [10.1021/jm00390a017] |
| 3. Doweyko AM.. (1988) The hypothetical active site lattice. An approach to modelling active sites from data on inhibitor molecules., 31 (7): [PMID:3290487] [10.1021/jm00402a025] |
| 4. Coats EA, Genther CS, Dietrich SW, Guo ZR, Hansch C.. (1981) Comparison of the inhibition of methotrexate-sensitive and -resistant Lactobacillus casei cell cultures with purified Lactobacillus casei dihydrofolate reductase by 4,6-diamino-1,2-dihydro-2,2-dimethyl-1-(3-substituted-phenyl)-s-triazines. Use of quantitative structure-activity relationships in making inferences about the mechanism of resistance and the structure of the enzyme is situ compared with the enzyme in vitro., 24 (12): [PMID:6796688] [10.1021/jm00144a010] |
| 5. Hansch C, Hathaway BA, Guo ZR, Selassie CD, Dietrich SW, Blaney JM, Langridge R, Volz KW, Kaufman BT.. (1984) Crystallography, quantitative structure-activity relationships, and molecular graphics in a comparative analysis of the inhibition of dihydrofolate reductase from chicken liver and Lactobacillus casei by 4,6-diamino-1,2-dihydro-2,2-dimethyl-1-(substituted-phenyl)-s-triazine s., 27 (2): [PMID:6420569] [10.1021/jm00368a006] |
| 6. Khwaja TA, Pentecost S, Selassie CD, Guo Z, Hansch C.. (1982) Comparison of quantitative structure-activity relationships of the inhibition of leukemia cells in culture with the inhibition of dihydrofolate reductase from leukemia cells and other cell types., 25 (2): [PMID:7057420] [10.1021/jm00344a012] |
| 7. Selassie CD, Guo Z, Hansch C, Khwaja TA, Pentecost S.. (1982) A comparison of the inhibition of growth of methotrexate-resistant and -sensitive leukemia cells in culture by triazines. Evidence for a new mechanism of cell resistance to methotrexate., 25 (2): [PMID:7057421] [10.1021/jm00344a013] |
| 8. Coats EA, Genther CS, Selassie CD, Strong CD, Hansch C.. (1985) Quantitative structure-activity relationship of antifolate inhibition of bacteria cell cultures resistant and sensitive to methotrexate., 28 (12): [PMID:3934385] [10.1021/jm00150a026] |
| 9. Crippen GM.. (1997) Validation of EGSITE2, a mixed integer program for deducing objective site models for experimental binding data., 40 (20): [PMID:9379435] [10.1021/jm970211n] |
| 10. Selassie CD, Hansch C, Khwaja TA, Dias CB, Pentecost S.. (1984) Comparative structure-activity relationships of antifolate triazines inhibiting murine tumor cells sensitive and resistant to methotrexate., 27 (3): [PMID:6699880] [10.1021/jm00369a019] |
| 11. Marlowe CK, Selassie CD, Santi DV.. (1995) Quantitative structure-activity relationships of the inhibition of Pneumocystis carinii dihydrofolate reductase by 4,6-diamino-1,2-dihydro-2,2-dimethyl-1-(X-phenyl)-s-triazines., 38 (6): [PMID:7699713] [10.1021/jm00006a016] |
| 12. Srinivasan B, Tonddast-Navaei S, Skolnick J.. (2015) Ligand binding studies, preliminary structure-activity relationship and detailed mechanistic characterization of 1-phenyl-6,6-dimethyl-1,3,5-triazine-2,4-diamine derivatives as inhibitors of Escherichia coli dihydrofolate reductase., 103 [PMID:26414808] [10.1016/j.ejmech.2015.08.021] |
