sodium cyclohexylsulfamate (sodium cyclamate)

ID: ALA273977

Chembl Id: CHEMBL273977

Cas Number: 139-05-9

PubChem CID: 23665706

Product Number: S109887

Max Phase: Phase

Molecular Formula: C6H12NNaO3S

Molecular Weight: 201.22

Molecule Type: Small molecule

Names and Identifiers

Synonyms: Sodium cyclamate | SODIUM CYCLAMATE|139-05-9|Sodium N-cyclohexylsulfamate|Sodium cyclohexylsulfamate|Cyclamic acid sodium salt|Sucaryl sodium|Sodium cyclohexanesulfamate|Cyclamate sodium|Sulfamic acid, cyclohexyl-, monosodium salt|Cyclamate, sodium|Assugrin|Asugryn|Ibiosuc|Suessette|Suestamin|Sugarin|Sugaron|Sodium sucaryl|Dulzor-Etas|Hachi-Sugar|Sucrum 7|Cyclamate, sodium salt|Natriumzyklamate|Cyclohexylsulfamate sodium|CHEBI:82431|Cyclamate sodium/ saccharin sodium|Cyclamic acid (sodium)|1I6F4Show More⌵

Canonical SMILES:  O=S(=O)([O-])NC1CCCCC1.[Na+]

Standard InChI:  InChI=1S/C6H13NO3S.Na/c8-11(9,10)7-6-4-2-1-3-5-6;/h6-7H,1-5H2,(H,8,9,10);/q;+1/p-1

Standard InChI Key:  UDIPTWFVPPPURJ-UHFFFAOYSA-M

Alternative Forms

1. Parent:

   

   ALA273977

   SODIUM CYCLAMATE

Molecule Features

Natural Product: No

Oral: No

Chemical Probe: No

Parenteral: No

Molecule Type: Small molecule

Topical: No

First In Class: No

Black Box: No

Chirality: Yes

Availability: No

Prodrug: No

Calculated Properties

Molecular Weight: 201.22

Molecular Weight (Monoisotopic): 201.0436

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References

1. Wiley RA, Pearson DA, Schmidt V, Wesche SB, Roxon JJ..  (1983)  Synthesis and bacterial metabolism of cis- and trans-2-alkyl analogues of sodium cyclamate.,  26  (7): [PMID:6191033] [10.1021/jm00361a025]

2. DuBois GE, Stephenson RA..  (1985)  Diterpenoid sweeteners. Synthesis and sensory evaluation of stevioside analogues with improved organoleptic properties.,  28  (1): [PMID:3965718] [10.1021/jm00379a017]

3. Talevi A, Enrique AV, Bruno-Blanch LE..  (2012)  Anticonvulsant activity of artificial sweeteners: a structural link between sweet-taste receptor T1R3 and brain glutamate receptors.,  22  (12): [PMID:22579423] [10.1016/j.bmcl.2012.04.076]

4. USP Dictionary of USAN and International Names (2010 edition) and USAN registrations 2007-date, 

5. PubChem BioAssay data set, 

6. Villalba ML, Palestro P, Ceruso M, Gonzalez Funes JL, Talevi A, Bruno Blanch L, Supuran CT, Gavernet L..  (2016)  Sulfamide derivatives with selective carbonic anhydrase VII inhibitory action.,  24  (4): [PMID:26795114] [10.1016/j.bmc.2016.01.012]

7.  (2013)  Methods To Identify Modulators, 

8.  (2013)  Methods To Identify Modulators of TAS2R48 Receptors, 

Source

Source(4):

• Scientific Literature
• PubChem BioAssays
• USP Dictionary of USAN and International Drug Names
• Patent Bioactivity Data