(S)-2-((S)-2-acetamido-3-(4-hydroxyphenyl)propanamido)-N1-((6S,9S,15S,18S,21S,24S)-1-amino-21-(2-amino-2-oxoethyl)-6-((S)-1-amino-3-(4-hydroxyphenyl)-1-oxopropan-2-ylcarbamoyl)-15-benzyl-18-(hydroxymethyl)-1-imino-9-isobutyl-8,11,14,17,20,23,30-heptaoxo-2,7,10,13,16,19,22,29-octaazapentatetracontan-24-yl)succinamide

ID: ALA3422513

Chembl Id: CHEMBL3422513

PubChem CID: 118735682

Max Phase: Preclinical

Molecular Formula: C76H117N17O17

Molecular Weight: 1540.87

Molecule Type: Small molecule

Names and Identifiers

Canonical SMILES:  CCCCCCCCCCCCCCCC(=O)NCCCC[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(C)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O

Standard InChI:  InChI=1S/C76H117N17O17/c1-5-6-7-8-9-10-11-12-13-14-15-16-20-28-65(100)82-37-22-21-26-54(87-73(108)60(43-63(77)98)92-72(107)59(85-48(4)95)42-51-31-35-53(97)36-32-51)70(105)91-61(44-64(78)99)74(109)93-62(46-94)75(110)90-58(41-49-24-18-17-19-25-49)68(103)84-45-66(101)86-57(39-47(2)3)71(106)88-55(27-23-38-83-76(80)81)69(104)89-56(67(79)102)40-50-29-33-52(96)34-30-50/h17-19,24-25,29-36,47,54-62,94,96-97H,5-16,20-23,26-28,37-46H2,1-4H3,(H2,77,98)(H2,78,99)(H2,79,102)(H,82,100)(H,84,103)(H,85,95)(H,86,101)(H,87,108)(H,88,106)(H,89,104)(H,90,110)(H,91,105)(H,92,107)(H,93,109)(H4,80,81,83)/t54-,55-,56-,57-,58-,59-,60-,61-,62-/m0/s1

Standard InChI Key:  RGTKOGRZZGFEMK-CRYQQEPOSA-N

Alternative Forms

1. Parent:

   

   ALA3422513

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Molecule Features

Natural Product: No

Oral: No

Chemical Probe: No

Parenteral: No

Molecule Type: Small molecule

Topical: No

First In Class: No

Black Box: No

Chirality: No

Availability: No

Prodrug: No

Calculated Properties

Molecular Weight: 1540.87

Molecular Weight (Monoisotopic): 1539.8813

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References

1. Beltramo M, Robert V, Galibert M, Madinier JB, Marceau P, Dardente H, Decourt C, De Roux N, Lomet D, Delmas AF, Caraty A, Aucagne V..  (2015)  Rational design of triazololipopeptides analogs of kisspeptin inducing a long-lasting increase of gonadotropins.,  58  (8): [PMID:25811530] [10.1021/jm5019675]

Source

Source(1):

• Scientific Literature