N-((2S,3S,5R)-2-(((tert-Butyldimethylsilyl)oxy)methyl)-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3-yl)-4-morpholinobenzamide

ID: ALA3578066

Chembl Id: CHEMBL3578066

PubChem CID: 122178234

Max Phase: Preclinical

Molecular Formula: C27H40N4O6Si

Molecular Weight: 544.73

Molecule Type: Small molecule

Names and Identifiers

Canonical SMILES:  Cc1cn([C@H]2C[C@H](NC(=O)c3ccc(N4CCOCC4)cc3)[C@@H](CO[Si](C)(C)C(C)(C)C)O2)c(=O)[nH]c1=O

Standard InChI:  InChI=1S/C27H40N4O6Si/c1-18-16-31(26(34)29-24(18)32)23-15-21(22(37-23)17-36-38(5,6)27(2,3)4)28-25(33)19-7-9-20(10-8-19)30-11-13-35-14-12-30/h7-10,16,21-23H,11-15,17H2,1-6H3,(H,28,33)(H,29,32,34)/t21-,22+,23+/m0/s1

Standard InChI Key:  XHHMCJSYLBVZCF-YTFSRNRJSA-N

Alternative Forms

1. Parent:

   

   ALA3578066

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Molecule Features

Natural Product: No

Oral: No

Chemical Probe: No

Parenteral: No

Molecule Type: Small molecule

Topical: No

First In Class: No

Black Box: No

Chirality: No

Availability: No

Prodrug: No

Calculated Properties

Molecular Weight: 544.73

Molecular Weight (Monoisotopic): 544.2717

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References

1. Vernekar SK, Qiu L, Zhang J, Kankanala J, Li H, Geraghty RJ, Wang Z..  (2015)  5'-Silylated 3'-1,2,3-triazolyl Thymidine Analogues as Inhibitors of West Nile Virus and Dengue Virus.,  58  (9): [PMID:25909386] [10.1021/acs.jmedchem.5b00327]

Source

Source(1):

• Scientific Literature