N-((2S,3S,5R)-2-(((tert-But1-((2S,3S,5R)-2-(((tert-Butyldimethylsilyl)oxy)-methyl)-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-tetrahydrofuran-3-yl)-3-phenylurea

ID: ALA3578067

Chembl Id: CHEMBL3578067

PubChem CID: 122178235

Max Phase: Preclinical

Molecular Formula: C23H34N4O5Si

Molecular Weight: 474.63

Molecule Type: Small molecule

Names and Identifiers

Canonical SMILES:  Cc1cn([C@H]2C[C@H](NC(=O)Nc3ccccc3)[C@@H](CO[Si](C)(C)C(C)(C)C)O2)c(=O)[nH]c1=O

Standard InChI:  InChI=1S/C23H34N4O5Si/c1-15-13-27(22(30)26-20(15)28)19-12-17(25-21(29)24-16-10-8-7-9-11-16)18(32-19)14-31-33(5,6)23(2,3)4/h7-11,13,17-19H,12,14H2,1-6H3,(H2,24,25,29)(H,26,28,30)/t17-,18+,19+/m0/s1

Standard InChI Key:  YWNGKIFQKBXGGM-IPMKNSEASA-N

Alternative Forms

1. Parent:

   

   ALA3578067

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Molecule Features

Natural Product: No

Oral: No

Chemical Probe: No

Parenteral: No

Molecule Type: Small molecule

Topical: No

First In Class: No

Black Box: No

Chirality: No

Availability: No

Prodrug: No

Calculated Properties

Molecular Weight: 474.63

Molecular Weight (Monoisotopic): 474.2298

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References

1. Vernekar SK, Qiu L, Zhang J, Kankanala J, Li H, Geraghty RJ, Wang Z..  (2015)  5'-Silylated 3'-1,2,3-triazolyl Thymidine Analogues as Inhibitors of West Nile Virus and Dengue Virus.,  58  (9): [PMID:25909386] [10.1021/acs.jmedchem.5b00327]

Source

Source(1):

• Scientific Literature