N-(((2S,3S,5R)-2-(((tert-Butyldimethylsilyl)oxy)methyl)-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3-yl)-carbamoyl)-4-methylbenzenesulfonamide

ID: ALA3578068

Chembl Id: CHEMBL3578068

PubChem CID: 122178236

Max Phase: Preclinical

Molecular Formula: C24H36N4O7SSi

Molecular Weight: 552.73

Molecule Type: Small molecule

Names and Identifiers

Canonical SMILES:  Cc1ccc(S(=O)(=O)NC(=O)N[C@H]2C[C@H](n3cc(C)c(=O)[nH]c3=O)O[C@@H]2CO[Si](C)(C)C(C)(C)C)cc1

Standard InChI:  InChI=1S/C24H36N4O7SSi/c1-15-8-10-17(11-9-15)36(32,33)27-22(30)25-18-12-20(28-13-16(2)21(29)26-23(28)31)35-19(18)14-34-37(6,7)24(3,4)5/h8-11,13,18-20H,12,14H2,1-7H3,(H2,25,27,30)(H,26,29,31)/t18-,19+,20+/m0/s1

Standard InChI Key:  TZLBDAXJYTYRQB-XUVXKRRUSA-N

Alternative Forms

1. Parent:

   

   ALA3578068

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Molecule Features

Natural Product: No

Oral: No

Chemical Probe: No

Parenteral: No

Molecule Type: Small molecule

Topical: No

First In Class: No

Black Box: No

Chirality: No

Availability: No

Prodrug: No

Calculated Properties

Molecular Weight: 552.73

Molecular Weight (Monoisotopic): 552.2074

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References

1. Vernekar SK, Qiu L, Zhang J, Kankanala J, Li H, Geraghty RJ, Wang Z..  (2015)  5'-Silylated 3'-1,2,3-triazolyl Thymidine Analogues as Inhibitors of West Nile Virus and Dengue Virus.,  58  (9): [PMID:25909386] [10.1021/acs.jmedchem.5b00327]

Source

Source(1):

• Scientific Literature