1-((2R,4S,5S)-5-((tert-butyldimethylsilyloxy)methyl)-4-((S)-5-(phenanthren-9-yl)-1H-1,2,3-triazol-1-yl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione

ID: ALA3578069

Chembl Id: CHEMBL3578069

PubChem CID: 122178237

Max Phase: Preclinical

Molecular Formula: C32H37N5O4Si

Molecular Weight: 583.77

Molecule Type: Small molecule

Names and Identifiers

Canonical SMILES:  Cc1cn([C@H]2C[C@H](n3nncc3-c3cc4ccccc4c4ccccc34)[C@@H](CO[Si](C)(C)C(C)(C)C)O2)c(=O)[nH]c1=O

Standard InChI:  InChI=1S/C32H37N5O4Si/c1-20-18-36(31(39)34-30(20)38)29-16-26(28(41-29)19-40-42(5,6)32(2,3)4)37-27(17-33-35-37)25-15-21-11-7-8-12-22(21)23-13-9-10-14-24(23)25/h7-15,17-18,26,28-29H,16,19H2,1-6H3,(H,34,38,39)/t26-,28+,29+/m0/s1

Standard InChI Key:  ZEXAXBYOTYDSDZ-WIIGKZCBSA-N

Alternative Forms

1. Parent:

   

   ALA3578069

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Molecule Features

Natural Product: No

Oral: No

Chemical Probe: No

Parenteral: No

Molecule Type: Small molecule

Topical: No

First In Class: No

Black Box: No

Chirality: No

Availability: No

Prodrug: No

Calculated Properties

Molecular Weight: 583.77

Molecular Weight (Monoisotopic): 583.2615

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References

1. Vernekar SK, Qiu L, Zhang J, Kankanala J, Li H, Geraghty RJ, Wang Z..  (2015)  5'-Silylated 3'-1,2,3-triazolyl Thymidine Analogues as Inhibitors of West Nile Virus and Dengue Virus.,  58  (9): [PMID:25909386] [10.1021/acs.jmedchem.5b00327]

Source

Source(1):

• Scientific Literature