(-)-((4aR,4bR,6aR,10aS,10bR,12aR)-9-(tert-butyldimethylsilyloxy)-1,1,4a,10b-tetramethyl-3,4,4a,4b,5,6,6a,7,10,10a,10b,11,12,12a-tetradecahydro-1H-spiro[chrysene-2,2'-[1,3]dioxolane]-10a-yl)methanimine

ID: ALA3601496

Chembl Id: CHEMBL3601496

PubChem CID: 122184961

Max Phase: Preclinical

Molecular Formula: C31H53NO3Si

Molecular Weight: 515.86

Molecule Type: Small molecule

Names and Identifiers

Canonical SMILES:  CC1(C)[C@@H]2CC[C@]3(C)[C@H](CC[C@@H]4CC=C(O[Si](C)(C)C(C)(C)C)C[C@]43C=N)[C@@]2(C)CCC12OCCO2

Standard InChI:  InChI=1S/C31H53NO3Si/c1-26(2,3)36(8,9)35-23-12-10-22-11-13-25-28(6)16-17-31(33-18-19-34-31)27(4,5)24(28)14-15-29(25,7)30(22,20-23)21-32/h12,21-22,24-25,32H,10-11,13-20H2,1-9H3/t22-,24-,25+,28-,29+,30-/m0/s1

Standard InChI Key:  WSXLGPLMCLSLRJ-WLVILIPRSA-N

Alternative Forms

1. Parent:

   

   ALA3601496

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Molecule Features

Natural Product: No

Oral: No

Chemical Probe: No

Parenteral: No

Molecule Type: Small molecule

Topical: No

First In Class: No

Black Box: No

Chirality: No

Availability: No

Prodrug: No

Calculated Properties

Molecular Weight: 515.86

Molecular Weight (Monoisotopic): 515.3795

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References

1. Lu J, Aguilar A, Zou B, Bao W, Koldas S, Shi A, Desper J, Wangemann P, Xie XS, Hua DH..  (2015)  Chemical synthesis of tetracyclic terpenes and evaluation of antagonistic activity on endothelin-A receptors and voltage-gated calcium channels.,  23  (17): [PMID:26190460] [10.1016/j.bmc.2015.06.055]

Source

Source(1):

• Scientific Literature