ID: ALA365539

Max Phase: Preclinical

Molecular Formula: C18H31Cl2N3PRu+2

Molecular Weight: 492.42

Molecule Type: Small molecule

Molecule Features

Natural Product: No

Oral: No

Chemical Probe: No

Parenteral: No

Molecule Type: Small molecule

Topical: No

First In Class: No

Black Box: No

Chirality: No

Availability: No

Prodrug: No

Properties

Molecular Weight: 492.42

Molecular Weight (Monoisotopic): 492.0665

AlogP:

#Rotatable Bonds:

Polar Surface Area:

Molecular Species:

HBA:

HBD:

#RO5 Violations:

HBA (Lipinski):

HBD (Lipinski):

#RO5 Violations (Lipinski):

CX Acidic pKa:

CX Basic pKa:

CX LogP:

CX LogD:

Aromatic Rings:

Heavy Atoms:

QED Weighted:

Np Likeness Score:

References

1. Scolaro C, Bergamo A, Brescacin L, Delfino R, Cocchietto M, Laurenczy G, Geldbach TJ, Sava G, Dyson PJ..  (2005)  In vitro and in vivo evaluation of ruthenium(II)-arene PTA complexes.,  48  (12): [PMID:15943488] [10.1021/jm050015d]

Source

Source(1):

• Scientific Literature