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2. North, E Jeffrey EJ and 5 more authors. 2010-04-22 Pharmacophore development and application toward the identification of novel, small-molecule autotaxin inhibitors. [PMID:20349977] |
3. Albers, Harald M H G HM and 5 more authors. 2010-07-08 Discovery and optimization of boronic acid based inhibitors of autotaxin. [PMID:20536182] |
4. Gupte, Renuka and 14 more authors. 2010-12-15 Synthesis and pharmacological evaluation of the stereoisomers of 3-carba cyclic-phosphatidic acid. [PMID:21051230] |
5. Castagna, Diana D, Budd, David C DC, Macdonald, Simon J F SJ, Jamieson, Craig C and Watson, Allan J B AJ. 2016-06-23 Development of Autotaxin Inhibitors: An Overview of the Patent and Primary Literature. [PMID:26745766] |
6. Ragle, Lauren E LE and 7 more authors. 2016-10-01 Discovery and synthetic optimization of a novel scaffold for hydrophobic tunnel-targeted autotaxin inhibition. [PMID:27544588] |
7. Jones, Spencer B SB and 19 more authors. 2016-09-08 Novel Autotaxin Inhibitors for the Treatment of Osteoarthritis Pain: Lead Optimization via Structure-Based Drug Design. [PMID:27660691] |
8. Shah, Pritom P and 23 more authors. 2016-11-15 Discovery of potent inhibitors of the lysophospholipase autotaxin. [PMID:27780639] |
9. Banerjee, Souvik S and 7 more authors. 2017-02-23 Highly Potent Non-Carboxylic Acid Autotaxin Inhibitors Reduce Melanoma Metastasis and Chemotherapeutic Resistance of Breast Cancer Stem Cells. [PMID:28112925] |
10. Desroy, Nicolas N and 29 more authors. 2017-05-11 Discovery of 2-[[2-Ethyl-6-[4-[2-(3-hydroxyazetidin-1-yl)-2-oxoethyl]piperazin-1-yl]-8-methylimidazo[1,2-a]pyridin-3-yl]methylamino]-4-(4-fluorophenyl)thiazole-5-carbonitrile (GLPG1690), a First-in-Class Autotaxin Inhibitor Undergoing Clinical Evaluation for the Treatment of Idiopathic Pulmonary Fibrosis. [PMID:28414242] |
11. Lanier, Marion M and 7 more authors. 2017-06-22 Repurposing Suzuki Coupling Reagents as a Directed Fragment Library Targeting Serine Hydrolases and Related Enzymes. [PMID:28564542] |
12. Balupuri, Anand A and 7 more authors. 2017-09-01 Design, synthesis, docking and biological evaluation of 4-phenyl-thiazole derivatives as autotaxin (ATX) inhibitors. [PMID:28743508] |
13. Baader, Manuel M and 6 more authors. 2018-02 Characterization of the properties of a selective, orally bioavailable autotaxin inhibitor in preclinical models of advanced stages of liver fibrosis. [PMID:29197066] |
14. Kuttruff, Christian A CA and 8 more authors. 2017-12-14 Discovery of BI-2545: A Novel Autotaxin Inhibitor That Significantly Reduces LPA Levels in Vivo. [PMID:29259743] |
15. Balupuri, Anand A and 15 more authors. 2018-03-25 Discovery and optimization of ATX inhibitors via modeling, synthesis and biological evaluation. [PMID:29477073] |
16. Nikolaou, Aikaterini A and 6 more authors. 2018-04-26 Hydroxamic Acids Constitute a Novel Class of Autotaxin Inhibitors that Exhibit in Vivo Efficacy in a Pulmonary Fibrosis Model. [PMID:29620892] |
17. Kawaguchi, Mitsuyasu and 11 more authors. 2020-03-26 Identification of Potent In Vivo Autotaxin Inhibitors that Bind to Both Hydrophobic Pockets and Channels in the Catalytic Domain. [PMID:32134652] |
18. Lei, Hongrui and 9 more authors. 2020-07-09 Discovery of Novel Indole-Based Allosteric Highly Potent ATX Inhibitors with Great In Vivo Efficacy in a Mouse Lung Fibrosis Model. [PMID:32479084] |
19. Iwaki, Yuzo and 20 more authors. 2020-06-11 ONO-8430506: A Novel Autotaxin Inhibitor That Enhances the Antitumor Effect of Paclitaxel in a Breast Cancer Model. [PMID:32551021] |
20. Cuozzo, John W and 13 more authors. 2020-07-23 Novel Autotaxin Inhibitor for the Treatment of Idiopathic Pulmonary Fibrosis: A Clinical Candidate Discovered Using DNA-Encoded Chemistry. [PMID:32584034] |
21. and Abdel-Magid, Ahmed F. 2020-11-12 Therapeutic Potential of Autotaxin Inhibitors in Treatment of Interstitial Lung Diseases. [PMID:33214812] |