Bis-(2-acetylbenzoato)triphenylbismuth(V)

ID: ALA3763483

Chembl Id: CHEMBL3763483

Max Phase: Preclinical

Molecular Formula: C36H29BiO6

Molecular Weight: 766.60

Molecule Type: Small molecule

Associated Items:

Alternative Forms

  1. Parent:

    ALA3763483

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Associated Targets(Human)

K562 (73714 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

B16-F10 (4610 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
L929 (3802 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Molecule Features

Natural Product: NoOral: NoChemical Probe: NoParenteral: No
Molecule Type: Small moleculeTopical: NoFirst In Class: NoBlack Box: No
Chirality: NoAvailability: NoProdrug: No

Drug Indications

MESH IDMESH Heading EFO IDsEFO TermsMax Phase for IndicationReferences

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Calculated Properties

Molecular Weight: 766.60Molecular Weight (Monoisotopic): 766.1768AlogP: #Rotatable Bonds:
Polar Surface Area: Molecular Species: HBA: HBD:
#RO5 Violations: HBA (Lipinski): HBD (Lipinski): #RO5 Violations (Lipinski):
CX Acidic pKa: CX Basic pKa: CX LogP: CX LogD:
Aromatic Rings: Heavy Atoms: QED Weighted: Np Likeness Score:

References

1. Islam A, Rodrigues BL, Marzano IM, Perreira-Maia EC, Dittz D, Paz Lopes MT, Ishfaq M, Frézard F, Demicheli C..  (2016)  Cytotoxicity and apoptotic activity of novel organobismuth(V) and organoantimony(V) complexes in different cancer cell lines.,  109  [PMID:26774931] [10.1016/j.ejmech.2016.01.003]

Source