(2S,3R)-3-(3-Boronophenyl)pyrrolidine-2-carboxylic Acid Hydrochloride

ID: ALA4060745

Chembl Id: CHEMBL4060745

PubChem CID: 137636365

Max Phase: Preclinical

Molecular Formula: C11H15BClNO4

Molecular Weight: 235.05

Molecule Type: Small molecule

Names and Identifiers

Canonical SMILES:  Cl.O=C(O)[C@H]1NCC[C@@H]1c1cccc(B(O)O)c1

Standard InChI:  InChI=1S/C11H14BNO4.ClH/c14-11(15)10-9(4-5-13-10)7-2-1-3-8(6-7)12(16)17;/h1-3,6,9-10,13,16-17H,4-5H2,(H,14,15);1H/t9-,10+;/m1./s1

Standard InChI Key:  XHYQQACLYQECIL-UXQCFNEQSA-N

Molecule Features

Natural Product: No

Oral: No

Chemical Probe: No

Parenteral: No

Molecule Type: Small molecule

Topical: No

First In Class: No

Black Box: No

Chirality: No

Availability: No

Prodrug: No

Calculated Properties

Molecular Weight: 235.05

Molecular Weight (Monoisotopic): 235.1016

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References

1. Gynther M, Proietti Silvestri I, Hansen JC, Hansen KB, Malm T, Ishchenko Y, Larsen Y, Han L, Kayser S, Auriola S, Petsalo A, Nielsen B, Pickering DS, Bunch L..  (2017)  Augmentation of Anticancer Drug Efficacy in Murine Hepatocellular Carcinoma Cells by a Peripherally Acting Competitive N-Methyl-d-aspartate (NMDA) Receptor Antagonist.,  60  (23): [PMID:29205034] [10.1021/acs.jmedchem.7b01624]

Source

Source(1):

• Scientific Literature