(2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine

ID: ALA406819

Chembl Id: CHEMBL406819

Max Phase: Preclinical

Molecular Formula: C9H10ClN5O2

Molecular Weight: 255.66

Molecule Type: Small molecule

Associated Items:

Names and Identifiers

Synonyms: Imidacloprid

Canonical SMILES:  O=[N+]([O-])/N=C1\NCCN1Cc1ccc(Cl)nc1

Standard InChI:  InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13)

Standard InChI Key:  YWTYJOPNNQFBPC-UHFFFAOYSA-N

Alternative Forms

  1. Parent:

    ALA406819

    IMIDACLOPRID

Associated Targets(Human)

CHRNB2 Tclin Neuronal acetylcholine receptor; alpha4/beta2 (3972 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MEN1 Tchem Menin/Histone-lysine N-methyltransferase MLL (48157 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KDM4A Tchem Lysine-specific demethylase 4A (52245 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
VDR Tclin Vitamin D receptor (26531 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
RGS4 Tchem Regulator of G-protein signaling 4 (13867 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CHRNA3 Tclin Neuronal acetylcholine receptor subunit alpha-3 (93 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CHRNA1 Tclin Acetylcholine receptor protein alpha chain (98 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CHRNA7 Tchem Neuronal acetylcholine receptor protein alpha-7 subunit (3524 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLCO1B3 Tchem Solute carrier organic anion transporter family member 1B3 (2517 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLCO1B1 Tchem Solute carrier organic anion transporter family member 1B1 (2672 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PLK1 Tchem Serine/threonine-protein kinase PLK1 (28605 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GALC Tbio Galactocerebrosidase (1984 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HDAC6 Tclin Histone deacetylase 6 (20808 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Chrna4 Neuronal acetylcholine receptor protein alpha-4 subunit (85 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Nicotinic acetylcholine receptor (4 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
nAChRbeta2 Nicotinic acetylcholine receptor (4 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Aphis gossypii (526 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Myzus persicae (1112 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CHRNA4 Neuronal acetylcholine receptor subunit alpha-4 (14 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mus musculus (284745 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Musca domestica (713 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Aphis craccivora (935 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Nilaparvata lugens (786 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ampC Beta-lactamase AmpC (62480 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
AOX1 Aldehyde oxidase (53 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PPO2 Tyrosinase (3884 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Brevicoryne brassicae (33 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Vitis vinifera (99 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Zea mays (820 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Gossypium hirsutum (233 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Glycine max (342 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
nAChRbeta2 Acetylcholine receptor subunit beta-like 2 (115 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Nephotettix cincticeps (805 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Laodelphax striatellus (278 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Bemisia tabaci (599 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Aphis fabae (223 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mythimna separata (3306 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Latrodectus hesperus (3 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Periplaneta americana (513 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Nicotinic acetylcholine receptor alpha8 subunit (79 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Encarsia inaron (58 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
mAChR-A Muscarinic acetylcholine receptor DM1 (50 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
nAChRalpha5 Nicotinic acetylcholine receptor alpha 5 subunit (134 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Trichogramma nubilale (84 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Aphis medicaginis (140 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Acetylcholine-binding protein (240 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Soluble acetylcholine receptor (39 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Frankliniella fusca (15 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Tetranychus cinnabarinus (1124 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Agrilus planipennis (6 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Oryza sativa (2923 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Sogatella furcifera (63 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Rhopalosiphum padi (121 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Apolygus lucorum (74 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Diaphorina citri (62 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Cotyledon (2 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Leaf (8 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Spodoptera litura (1708 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Cheumatopsyche (45 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Daphnia magna (43 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Rhynchophorus ferrugineus (189 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Root (2 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Gomar (2 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Leaf base (2 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Rachis (2 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Pinnae (2 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Cnaphalocrocis medinalis (89 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Plutella xylostella (1838 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Amblyseius andersoni (1 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Neoseiulus fallacis (1 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Galendromus occidentalis (74 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Salmonella typhimurium (15756 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Leuciscus idus (1 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Rattus norvegicus (775804 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Lepidoptera (26 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Chrna4 Neuronal acetylcholine receptor protein alpha-4 subunit (8 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Apis mellifera (12 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Contarinia nasturtii (23 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Ceutorhynchus obstrictus (26 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Abdominal central nerve cord (25 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Aulacophora femoralis (26 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Frankliniella occidentalis (90 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Urochloa mutica (12 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Lygaeidae (21 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Reticulitermes flavipes (47 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CHRNA1 Acetylcholine receptor protein alpha chain (109 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Amphimallon majale (27 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Anomala orientalis (27 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Maladera castanea (27 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Popillia japonica (46 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Paralobesia (6 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SARS-CoV-2 (38078 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rep Replicase polyprotein 1ab (11336 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Molecule Features

Natural Product: NoOral: NoChemical Probe: NoParenteral: No
Molecule Type: Small moleculeTopical: NoFirst In Class: NoBlack Box: No
Chirality: NoAvailability: NoProdrug: No

Drug Indications

MESH IDMESH Heading EFO IDsEFO TermsMax Phase for IndicationReferences

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Calculated Properties

Molecular Weight: 255.66Molecular Weight (Monoisotopic): 255.0523AlogP: 0.69#Rotatable Bonds: 3
Polar Surface Area: 83.66Molecular Species: NEUTRALHBA: 3HBD: 1
#RO5 Violations: 0HBA (Lipinski): 7HBD (Lipinski): 1#RO5 Violations (Lipinski): 0
CX Acidic pKa: CX Basic pKa: CX LogP: 0.53CX LogD: 0.53
Aromatic Rings: 1Heavy Atoms: 17QED Weighted: 0.49Np Likeness Score: -1.29

References

1. Bruno-Blanch L, Gálvez J, García-Domenech R..  (2003)  Topological virtual screening: a way to find new anticonvulsant drugs from chemical diversity.,  13  (16): [PMID:12873507] [10.1016/s0960-894x(03)00535-3]
2. Zhang N, Tomizawa M, Casida JE..  (2002)  Structural features of azidopyridinyl neonicotinoid probes conferring high affinity and selectivity for mammalian alpha4beta2 and Drosophila nicotinic receptors.,  45  (13): [PMID:12061885] [10.1021/jm010508s]
3. Kagabu S, Maienfisch P, Zhang A, Granda-Minones J, Haettenschwiler J, Kayser H, Maetzke T, Casida JE..  (2000)  5-Azidoimidacloprid and an acyclic analogue as candidate photoaffinity probes for mammalian and insect nicotinic acetylcholine receptors.,  43  (26): [PMID:11150171] [10.1021/jm000240p]
4. Fujikawa M, Nakao K, Shimizu R, Akamatsu M..  (2007)  QSAR study on permeability of hydrophobic compounds with artificial membranes.,  15  (11): [PMID:17418579] [10.1016/j.bmc.2007.03.040]
5. Tomizawa M, Talley TT, Maltby D, Durkin KA, Medzihradszky KF, Burlingame AL, Taylor P, Casida JE..  (2007)  Mapping the elusive neonicotinoid binding site.,  104  (21): [PMID:17485662] [10.1073/pnas.0703309104]
6. Clark DA, Lahm GP, Smith BK, Barry JD, Clagg DG..  (2008)  Synthesis of insecticidal fluorinated anthranilic diamides.,  16  (6): [PMID:18207749] [10.1016/j.bmc.2007.12.017]
7. Tomizawa M, Kagabu S, Ohno I, Durkin KA, Casida JE..  (2008)  Potency and selectivity of trifluoroacetylimino and pyrazinoylimino nicotinic insecticides and their fit at a unique binding site niche.,  51  (14): [PMID:18570364] [10.1021/jm800191a]
8. Shao X, Zhang W, Peng Y, Li Z, Tian Z, Qian X..  (2008)  cis-Nitromethylene neonicotinoids as new nicotinic family: synthesis, structural diversity, and insecticidal evaluation of hexahydroimidazo[1,2-alpha]pyridine.,  18  (24): [PMID:18951786] [10.1016/j.bmcl.2008.10.048]
9. Kagabu S, Takagi M, Ohno I, Mikawa T, Miyamoto T..  (2009)  Crown-capped imidacloprid: a novel design and insecticidal activity.,  19  (11): [PMID:19409782] [10.1016/j.bmcl.2009.04.053]
10. PubChem BioAssay data set, 
11. PubChem BioAssay data set, 
12. PubChem BioAssay data set, 
13. Shao X, Xu Z, Zhao X, Xu X, Tao L, Li Z, Qian X..  (2010)  Synthesis, crystal structure, and insecticidal activities of highly congested hexahydroimidazo[1,2-a]pyridine derivatives: effect of conformation on activities.,  58  (5): [PMID:20000414] [10.1021/jf902513t]
14. Shao X, Fu H, Xu X, Xu X, Liu Z, Li Z, Qian X..  (2010)  Divalent and oxabridged neonicotinoids constructed by dialdehydes and nitromethylene analogues of imidacloprid: design, synthesis, crystal structure, and insecticidal activities.,  58  (5): [PMID:20000569] [10.1021/jf902531y]
15. Zhang W, Yang X, Chen W, Xu X, Li L, Zhai H, Li Z..  (2010)  Design, multicomponent synthesis, and bioactivities of novel neonicotinoid analogues with 1,4-dihydropyridine scaffold.,  58  (5): [PMID:20000775] [10.1021/jf902034z]
16. Sun C, Xu X, Xu Y, Yan D, Fang T, Liu T..  (2011)  Synthesis, insecticidal activity, and molecular docking studies of nitenpyram analogues with a flexible ester arm anchored on tetrahydropyrimidine ring.,  59  (9): [PMID:21469732] [10.1021/jf1049563]
17. Ford KA, Gulevich AG, Swenson TL, Casida JE..  (2011)  Neonicotinoid insecticides: oxidative stress in planta and metallo-oxidase inhibition.,  59  (9): [PMID:21476569] [10.1021/jf200485k]
18. Shang J, Sun R, Li Y, Huang R, Bi F, Wang Q..  (2010)  Synthesis and insecticidal evaluation of N-tert-butyl-N'-thio[1-(6-chloro-3-pyridylmethyl)-2-nitroiminoimidazolidine]-N,N'-diacylhydrazines.,  58  (3): [PMID:20041716] [10.1021/jf903642s]
19. Chae SH, Kim SI, Yeon SH, Lee SW, Ahn YJ..  (2011)  Adulticidal activity of phthalides identified in Cnidium officinale rhizome to B- and Q-biotypes of Bemisia tabaci.,  59  (15): [PMID:21728333] [10.1021/jf201927t]
20. Ye Z, Xia S, Shao X, Cheng J, Xu X, Xu Z, Li Z, Qian X..  (2011)  Design, synthesis, crystal structure analysis, and insecticidal evaluation of phenylazoneonicotinoids.,  59  (19): [PMID:21894959] [10.1021/jf2029708]
21. Lu S, Shao X, Li Z, Xu Z, Zhao S, Wu Y, Xu X..  (2012)  Design, synthesis, and particular biological behaviors of chain-opening nitromethylene neonicotinoids with cis configuration.,  60  (1): [PMID:22122797] [10.1021/jf203068a]
22. Shao X, Li Z, Qian X, Xu X..  (2009)  Design, synthesis, and insecticidal activities of novel analogues of neonicotinoids: replacement of nitromethylene with nitroconjugated system.,  57  (3): [PMID:19138119] [10.1021/jf803305f]
23. Zhang W, Chen Y, Chen W, Liu Z, Li Z..  (2010)  Designing Tetrahydroimidazo[1,2-a]pyridine derivatives via catalyst-free Aza-Diels-Alder reaction (ADAR) and their insecticidal evaluation.,  58  (10): [PMID:20423095] [10.1021/jf100645y]
24. Su W, Zhou Y, Ma Y, Wang L, Zhang Z, Rui C, Duan H, Qin Z..  (2012)  N'-Nitro-2-hydrocarbylidenehydrazinecarboximidamides: design, synthesis, crystal structure, insecticidal activity, and structure-activity relationships.,  60  (20): [PMID:22546079] [10.1021/jf300616x]
25. Ohno I, Tomizawa M, Durkin KA, Casida JE, Kagabu S..  (2009)  Neonicotinoid substituents forming a water bridge at the nicotinic acetylcholine receptor.,  57  (6): [PMID:19253973] [10.1021/jf803985r]
26. Wakita T..  (2011)  Molecular design of dinotefuran with unique insecticidal properties.,  59  (7): [PMID:20919736] [10.1021/jf1030778]
27. Shao X, Lee PW, Liu Z, Xu X, Li Z, Qian X..  (2011)  cis-Configuration: a new tactic/rationale for neonicotinoid molecular design.,  59  (7): [PMID:21043520] [10.1021/jf103499x]
28. Zhu Y, Loso MR, Watson GB, Sparks TC, Rogers RB, Huang JX, Gerwick BC, Babcock JM, Kelley D, Hegde VB, Nugent BM, Renga JM, Denholm I, Gorman K, DeBoer GJ, Hasler J, Meade T, Thomas JD..  (2011)  Discovery and characterization of sulfoxaflor, a novel insecticide targeting sap-feeding pests.,  59  (7): [PMID:21105655] [10.1021/jf102765x]
29. Ou J, Zhu X, Wang L, Xu C, Liu F, Ren L, Xu X, Wang Y, Rui C, Liu S..  (2012)  Synthesis and bioactivity study of 2-acylamino-substituted N'-benzylbenzohydrazide derivatives.,  60  (44): [PMID:23088717] [10.1021/jf303376t]
30. Tian Z, Shao X, Li Z, Qian X, Huang Q..  (2007)  Synthesis, insecticidal activity, and QSAR of novel nitromethylene neonicotinoids with tetrahydropyridine fixed cis configuration and exo-ring ether modification.,  55  (6): [PMID:17311404] [10.1021/jf063418a]
31. Honda H, Tomizawa M, Casida JE..  (2007)  Insect muscarinic acetylcholine receptor: pharmacological and toxicological profiles of antagonists and agonists.,  55  (6): [PMID:17319687] [10.1021/jf0631934]
32. Dai H, Li YQ, Du D, Qin X, Zhang X, Yu HB, Fang JX..  (2008)  Synthesis and biological activities of novel pyrazole oxime derivatives containing a 2-chloro-5-thiazolyl moiety.,  56  (22): [PMID:18959421] [10.1021/jf802429x]
33. Wang HY, Yang Y, Su JY, Shen JL, Gao CF, Zhu YC..  (2008)  Assessment of the impact of insecticides on Anagrus nilaparvatae (Pang et Wang) (Hymenoptera: Mymanidae), an egg parasitoid of the rice planthopper, Nilaparvata lugens (Hemiptera: Delphacidae),  27  (3): [10.1016/j.cropro.2007.08.004]
34. Mota-Sanchez D, Cregg BM, McCullough DG, Poland TM, Hollingworth RM..  (2009)  Distribution of trunk-injected ¹⁴C-imidacloprid in ash trees and effects on emerald ash borer (Coleoptera: Buprestidae) adults,  28  (8): [10.1016/j.cropro.2009.03.012]
35. Cudworth DP, Hegde VB, Yap MC, Guenthenspberger KA, Hamilton CT, Pechacek JT, Johnson PL, Bis SJ, Tisdell FE, Dripps JE, Bruce TJ, Dintenfass LP, Gifford JM, Karr LL, Kempe MK, McCormick DC, Schoonover JR..  (2007)  Structure-activity relationship development of dihaloaryl triazole compounds as insecticides and acaricides. 1. Phenyl thiophen-2-yl triazoles.,  55  (18): [PMID:17696361] [10.1021/jf071498s]
36. Suri KS, Singh G..  (2011)  Insecticide-induced resurgence of the whitebacked planthopper Sogatella furcifera (Horvath) (Hemiptera: Delphacidae) on rice varieties with different levels of resistance,  30  (2): [10.1016/j.cropro.2010.11.008]
37. Sohrabi F, Shishehbor P, Saber M, Mosaddegh MS..  (2011)  Lethal and sublethal effects of buprofezin and imidacloprid on Bemisia tabaci (Hemiptera: Aleyrodidae),  30  (9): [10.1016/j.cropro.2011.05.004]
38. Sohrabi Fariba, Shishehbor Parviz, Saber Moosa, Mosaddegh MohammadSaid..  (2012)  Lethal and sublethal effects of buprofezin and imidacloprid on the whitefly parasitoid Encarsia inaron (Hymenoptera: Aphelinidae),  32  [10.1016/j.cropro.2011.10.005]
39. Wang Y, Yu R, Zhao X, Chen L, Wu C, Cang T, Wang Q..  (2012)  Susceptibility of adult Trichogramma nubilale (Hymenoptera: Trichogrammatidae) to selected insecticides with different modes of action,  34  [10.1016/j.cropro.2011.12.007]
40. Basit M, Saleem MA, Shafqat S, Sayyed AH..  (2012)  Cross resistance, genetic analysis and stability of resistance to buprofezin in cotton whitefly, Bemisia tabaci (Homoptera: Aleyrodidae),  40  [10.1016/j.cropro.2012.03.024]
41. Groves R, Sorenson C, Walgenbach J, Kennedy G.  (2001)  Effects of imidacloprid on transmission of tomato spotted wilt tospovirus to pepper, tomato and tobacco by Frankliniella fusca Hinds (Thysanoptera: Thripidae),  20  (5): [10.1016/S0261-2194(00)00171-X]
42. Kagabu S..  (2011)  Discovery of imidacloprid and further developments from strategic molecular designs.,  59  (7): [PMID:20718435] [10.1021/jf101824y]
43. Akamatsu M..  (2011)  Importance of physicochemical properties for the design of new pesticides.,  59  (7): [PMID:20879794] [10.1021/jf102525e]
44. Kagabu S, Ohno I, Tomizawa M, Durkin KA, Matsuura R, Uchiyama D, Nagae N, Kumazawa S..  (2010)  Furan-2,5-dimethylene-tethered bis-imidacloprid insecticide conferring high potency.,  58  (22): [PMID:20973548] [10.1021/jf102819n]
45. Sun C, Zhu J, Wang H, Jin J, Xing J, Yang D..  (2011)  Chiral 1,5-disubstituted 1,3,5-hexahydrotriazine-2-N-nitroimine analogues as novel potent neonicotinoids: Synthesis, insecticidal evaluation and molecular docking studies.,  46  (1): [PMID:21093112] [10.1016/j.ejmech.2010.09.047]
46. Tomizawa M, Casida JE..  (2011)  Unique neonicotinoid binding conformations conferring selective receptor interactions.,  59  (7): [PMID:21341671] [10.1021/jf1019455]
47. Kagabu S, Ishihara R, Hieda Y, Nishimura K, Naruse Y..  (2007)  Insecticidal and neuroblocking potencies of variants of the imidazolidine moiety of imidacloprid-related neonicotinoids and the relationship to partition coefficient and charge density on the pharmacophore.,  55  (3): [PMID:17263479] [10.1021/jf0623440]
48. Suzuki J, Okamura D, Gushikawa T, Hirai K, Ando T.  (2011)  Synthesis and insecticidal activity of 1,2,4-oxadiazole and 1,2,4-thiadiazole derivatives,  36  (3): [10.1584/jpestics.G11-28]
49. Kagabu S, Kato C, Nishimura K.  (2004)  Insecticidal and Neuroblocking Activities toward American Cockroach (Periplaneta americana L.) of Imidacloprid Metabolites, 5-Hydroxy-, 4,5-Dihydroxy- and 4,5-Dehydroimidacloprid,  29  (4): [10.1584/jpestics.29.376]
50. Zhang A, Kayser H, Maienfisch P, Casida JE..  (2000)  Insect nicotinic acetylcholine receptor: conserved neonicotinoid specificity of [(3)H]imidacloprid binding site.,  75  (3): [PMID:10936213] [10.1046/j.1471-4159.2000.751294.x]
51. Shiokawa K, Moriya K, Shibuya K, Hattori Y, Tsuboi S, Kagabu S.  (1992)  3-(6-Chloronicotinyl)-2-nitromethylene-thiazolidine as a New Class of Insecticide Acting against Lepidoptera Species,  56  (8): [10.1271/bbb.56.1364]
52. Wang YH, Liu XG, Zhu YC, Wu SG, Li SY, Chen WM, Shen JL..  (2009)  Inheritance mode and realized heritability of resistance to imidacloprid in the brown planthopper, Nilaparvata lugens (Stål) (Homoptera: Delphacidae).,  65  (6): [PMID:19206094] [10.1002/ps.1720]
53. Bostanian NJ, Thistlewood HA, Hardman JM, Laurin MC, Racette G..  (2009)  Effect of seven new orchard pesticides on Galendromus occidentalis in laboratory studies.,  65  (6): [PMID:19206104] [10.1002/ps.1721]
54. Ma Y, Gao Z, Dang Z, Li Y, Pan W.  (2012)  Effect of temperature on the toxicity of several insecticides to Apolygus lucorum (Heteroptera: Miridae),  37  (2): [10.1584/jpestics.D11-013]
55. Tomizawa M, Lee DL, Casida JE..  (2000)  Neonicotinoid insecticides: molecular features conferring selectivity for insect versus mammalian nicotinic receptors.,  48  (12): [PMID:11312774] [10.1021/jf000873c]
56. Wang Z, Yao M, Wu Y..  (2009)  Cross-resistance, inheritance and biochemical mechanisms of imidacloprid resistance in B-biotype Bemisia tabaci.,  65  (11): [PMID:19562662] [10.1002/ps.1808]
57. Dosdall LM..  (2009)  Responses of the cabbage seedpod weevil, Ceutorhynchus obstrictus (Marsham) (Coleoptera: Curculionidae), to seed treatments of canola (Brassica napus L.) with the neonicotinoid compounds clothianidin and imidacloprid.,  65  (12): [PMID:19642076] [10.1002/ps.1818]
58. Moriya K, Shibuya K, Hattori Y, Tsuboi S, Shiokawa K, Kagabu S.  (1992)  1-(6-Chloronicotinyl)-2-nitroimino-imidazolidines and Related Compounds as Potential New Insecticides,  56  (2): [10.1271/bbb.56.364]
59. Moriya K, Shibuya K, Hattori Y, Tsuboi S, Shiokawa K, Kagabu S..  (1993)  Structural Modification of the 6-Chloropyridyl Moiety in the Imidacloprid, Skeleton: Introduction of a Five-membered Heteroaromatic Ring and the Resulting Insecticidal Activity.,  57  (1): [PMID:27316887] [10.1271/bbb.57.127]
60. Kagabu S, Hieda Y, Ohno I.  (2007)  Preparation of 5-chloro-6-fluoroimidacloprid analogs and comparison of their insecticidal activity in a laboratory test with a 6-chloro-5-fluoro analog,  32  (3): [10.1584/jpestics.G07-04]
61. Yokoyama A, Ohtsu K, Iwafune T, Nagai T, Ishihara S, Kobara Y, Horio T, Endo S.  (2009)  A useful new insecticide bioassay using first-instar larvae of a net-spinning caddisfly, Cheumatopsyche brevilineata (Trichoptera: Hydropsychidae),  34  (1): [10.1584/jpestics.G08-26]
62. Yokoyama A, Ohtsu K, Iwafune T, Nagai T, Ishihara S, Kobara Y, Horio T, Endo S.  (2009)  Sensitivity difference to insecticides of a riverine caddisfly, Cheumatopsyche brevilineata (Trichoptera: Hydropsychidae), depending on the larval stages and strains,  34  (1): [10.1584/jpestics.G08-32]
63. Cui L, Sun L, Shao X, Cao Y, Yang D, Li Z, Yuan H..  (2010)  Systemic action of novel neonicotinoid insecticide IPP-10 and its effect on the feeding behaviour of Rhopalosiphum padi on wheat.,  66  (7): [PMID:20533381] [10.1002/ps.1942]
64. Gorman K, Slater R, Blande JD, Clarke A, Wren J, McCaffery A, Denholm I..  (2010)  Cross-resistance relationships between neonicotinoids and pymetrozine in Bemisia tabaci (Hemiptera: Aleyrodidae).,  66  (11): [PMID:20632380] [10.1002/ps.1989]
65. Mori M, Kikuchi M, Ohno I, Kagabu S.  (2010)  Unexpected plant-systemic insecticidal properties of alkylene-tethered bis-imidacloprid derivatives,  35  (2): [10.1584/jpestics.G09-46]
66. Tiwari S, Pelz-Stelinski K, Stelinski LL..  (2011)  Effect of Candidatus Liberibacter asiaticus infection on susceptibility of Asian citrus psyllid, Diaphorina citri, to selected insecticides.,  67  (1): [PMID:20960471] [10.1002/ps.2038]
67. Zhang L, Greenberg SM, Zhang Y, Liu TX..  (2011)  Effectiveness of thiamethoxam and imidacloprid seed treatments against Bemisia tabaci (Hemiptera: Aleyrodidae) on cotton.,  67  (2): [PMID:21077123] [10.1002/ps.2056]
68. Kaakeh W..  (2006)  Toxicity of imidacloprid to developmental stages of Rhynchophorus ferrugineus (Curculionidae: Coleoptera): Laboratory and field tests,  25  (5): [10.1016/j.cropro.2005.07.006]
69. Kagabu S, Kiriyama K, Nishiwaki H, Kumamoto Y, Tada T, Nishimura K..  (2003)  Asymmetric chloronicotinyl insecticide, 1-[1-(6-chloro-3-pyridyl)ethyl]-2-nitroiminoimidazolidine: preparation, resolution and biological activities toward insects and their nerve preparations.,  67  (5): [PMID:12834274] [10.1271/bbb.67.980]
70. Morales-Rodriguez A, Ospina A, Peck DC..  (2010)  Variation in the laboratory susceptibility of turf-infesting white grubs (Coleoptera: Scarabaeidae) to biological, biorational and chemical control products.,  66  (1): [PMID:19742452] [10.1002/ps.1835]
71. ENDO S, TSURUMACHI M.  (2000)  Insecticide Resistance and Insensitive Acetylcholinesterase in Small Brown Planthopper, Laodelphax striatellus,  25  (4): [10.1584/jpestics.25.395]
72. Feng Y, Wu Q, Wang S, Chang X, Xie W, Xu B, Zhang Y..  (2010)  Cross-resistance study and biochemical mechanisms of thiamethoxam resistance in B-biotype Bemisia tabaci (Hemiptera: Aleyrodidae).,  66  (3): [PMID:19937914] [10.1002/ps.1877]
73. KAGABU S, IWAYA K, KONISHI H, SAKAI A, ITAZU Y, KIRIYAMA K, NISHIMURA K.  (2002)  Synthesis of Alkylene-Tethered Bis-Imidacloprid Derivatives as Highly Insecticidal and Nerve-Exciting Agents with Potent Affinity to [3H] Imidacloprid-Binding Sites on Nicotinic Acetylcholine Receptor,  27  (3): [10.1584/jpestics.27.249]
74. SONE S, TSUBOI S, OTSU Y, SHONO T.  (1997)  Mechanisms of Low Susceptibility to Imidacloprid in a Laboratory Strain of the Small Brown Planthopper, Laodelphax striatellus FALLEN,  22  (3): [10.1584/jpestics.22.236]
75. TOMIZAWA M, YAMAMOTO I.  (1992)  Binding of Nicotinoids and the Related Compounds to the Insect Nicotinic Acetyicholine Receptor,  17  (4): [10.1584/jpestics.17.4_231]
76. KAGABU S, AZUMA A, NISHIMURA K.  (2002)  Insecticidal and Neuroblocking Activities of Thiacloprid and Its Acyclic Analogues and Their Related Cyanoguanidine Derivatives,  27  (3): [10.1584/jpestics.27.267]
77. KAGABU S, MATSUDA K, KOMAI K.  (2002)  Preparation of Dinotefuran Related Compounds and Agonistic Action on SAD2 Hybrid Nicotinic Acetylcholine Receptors Expressed in Xenopus laevis Oocytes,  27  (4): [10.1584/jpestics.27.374]
78. KIRIYAMA K, ITAZU Y, KAGABU S, NISHIMURA K.  (2003)  Insecticidal and Neuroblocking Activities of Acetamiprid and Related Compounds,  28  (1): [10.1584/jpestics.28.8]
79. Kiriyama K, Kagabu S, Nishimura K.  (2004)  Insecticidal Activities of the Enantiomers of Asymmetric 1-[1-(6-Chloro-3-pyridyl)ethyl]-2-nitroiminoimidazolidine against American Cockroach, Cucurbit Leaf Beetle, Green Rice Leafhopper and Green Peach Aphid Following Injection, Dipping and Spraying,  29  (1): [10.1584/jpestics.29.43]
80. Shi X, Jiang L, Wang H, Qiao K, Wang D, Wang K..  (2011)  Toxicities and sublethal effects of seven neonicotinoid insecticides on survival, growth and reproduction of imidacloprid-resistant cotton aphid, Aphis gossypii.,  67  (12): [PMID:21714058] [10.1002/ps.2207]
81. Peterson CJ..  (2012)  Bifenthrin longevity at the termiticidal application rate.,  68  (1): [PMID:21770011] [10.1002/ps.2232]
82. Nishimura K, Kiriyama K, Kagabu S.  (2006)  Quantitative structureactivity relationships of imidacloprid and its analogs with substituents at the C5 position on the pyridine ring in the neuroblocking activity,  31  (2): [10.1584/jpestics.31.110]
83. Kagabu S, Itazu Y, Nishimura K.  (2006)  1,6-Bis[1-(2-chloro-5-thiazolylmethyl)-2-nitroiminoimidazolidin-3-yl]hexane and 1,3,5-tris[1-(6-chloronicotinyl)-2-nitroiminoimidazolidin-3-ylmethyl]benzeneSynthesis and insecticidal and neuroblocking activities in American cockroaches, Periplaneta americana,  31  (2): [10.1584/jpestics.31.146]
84. Kagabu S, Fujii Y, Nishimura K.  (2006)  Insecticidal activity of imidacloprid derivatives with an alkoxy group at the C5 position of the pyridine ring,  31  (2): [10.1584/jpestics.31.150]
85. Ihara M, Brown LA, Ishida C, Okuda H, Sattelle DB, Matsuda K.  (2006)  Actions of imidacloprid, clothianidin and related neonicotinoids on nicotinic acetylcholine receptors of American cockroach neurons and their relationships with insecticidal potency,  31  (1): [10.1584/jpestics.31.35]
86. Van Timmeren S, Wise JC, Isaacs R..  (2012)  Soil application of neonicotinoid insecticides for control of insect pests in wine grape vineyards.,  68  (4): [PMID:22290809] [10.1002/ps.2285]
87. YAMAMOTO I, YABUTA G, TOMIZAWA M, SAITO T, MIYAMOTO T, KAGABU S.  (1995)  Molecular Mechanism for Selective Toxicity of Nicotinoids and Neonicotinoids,  20  (1): [10.1584/jpestics.20.33]
88. Kagabu S.  (2008)  Pharmacophore of neonicotinoid insecticides,  33  (1): [10.1584/jpestics.R07-05]
89. Guillén J, Bielza P..  (2013)  Thiamethoxam acts as a target-site synergist of spinosad in resistant strains of Frankliniella occidentalis.,  69  (2): [PMID:22847768] [10.1002/ps.3372]
90. Stamm MD, Heng-Moss TM, Baxendale FP, Siegfried BD, Gaussoin RE, Snow DD, Cassada DA..  (2013)  Effect of distribution and concentration of topically applied neonicotinoid insecticides in buffalograss, Buchloe dactyloides, leaf tissues on the differential mortality of Blissus occiduus under field conditions.,  69  (2): [PMID:22933384] [10.1002/ps.3387]
91. Cutler P, Slater R, Edmunds AJ, Maienfisch P, Hall RG, Earley FG, Pitterna T, Pal S, Paul VL, Goodchild J, Blacker M, Hagmann L, Crossthwaite AJ..  (2013)  Investigating the mode of action of sulfoxaflor: a fourth-generation neonicotinoid.,  69  (5): [PMID:23112103] [10.1002/ps.3413]
92. TOMIZAWA M, OTSUKA H, MIYAMOTO T, YAMAMOTO I.  (1995)  Pharmacological Effects of Imidacloprid and Its Related Compounds on the Nicotinic Acetyicholine Receptor with Its Ion Channel from the Torpedo Electric Organ,  20  (1): [10.1584/jpestics.20.49]
93. TOMIZAWA M, OTSUKA H, MIYAMOTO T, ELDEFRAWI ME, YAMAMOTO I.  (1995)  Pharmacological Characteristics of Insect Nicotinic Acetyicholine Receptor with Its Ion Channel and the Comparison of the Effect of Nicotinoids and Neonicotinoids,  20  (1): [10.1584/jpestics.20.57]
94. Tiwari S, Killiny N, Mann RS, Wenninger EJ, Stelinski LL..  (2013)  Abdominal color of the Asian citrus psyllid, Diaphorina citri, is associated with susceptibility to various insecticides.,  69  (4): [PMID:23193012] [10.1002/ps.3407]
95. Ye Z, Shi L, Shao X, Xu X, Xu Z, Li Z..  (2013)  Pyrrole- and dihydropyrrole-fused neonicotinoids: design, synthesis, and insecticidal evaluation.,  61  (2): [PMID:23256728] [10.1021/jf3044132]
96. Moores GD, Philippou D, Borzatta V, Trincia P, Jewess P, Gunning R, Bingham G..  (2009)  An analogue of piperonyl butoxide facilitates the characterisation of metabolic resistance.,  65  (2): [PMID:18951417] [10.1002/ps.1661]
97. PubChem BioAssay data set, 
98. PubChem BioAssay data set, 
99. De Bruyn T, van Westen GJ, Ijzerman AP, Stieger B, de Witte P, Augustijns PF, Annaert PP..  (2013)  Structure-based identification of OATP1B1/3 inhibitors.,  83  (6): [PMID:23571415] [10.1124/mol.112.084152]
100. PubChem BioAssay data set, 
101. PubChem BioAssay data set, 
102. Bao MF, Zeng CX, Liu YP, Zhang BJ, Ni L, Luo XD, Cai XH..  (2017)  Indole Alkaloids from Hunteria zeylanica.,  80  (4): [PMID:28362501] [10.1021/acs.jnatprod.5b01035]
103. Bernhard Ellinger, Denisa Bojkova, Andrea Zaliani, Jindrich Cinatl, Carsten Claussen, Sandra Westhaus, Jeanette Reinshagen, Maria Kuzikov, Markus Wolf, Gerd Geisslinger, Philip Gribbon, Sandra Ciesek.  (2020)  Identification of inhibitors of SARS-CoV-2 in-vitro cellular toxicity in human (Caco-2) cells using a large scale drug repurposing collection,  [10.21203/rs.3.rs-23951/v1]
104. Katie Heiser, Peter F. McLean, Chadwick T. Davis, Ben Fogelson, Hannah B. Gordon, Pamela Jacobson, Brett Hurst, Ben Miller, Ronald W. Alfa, Berton A. Earnshaw, Mason L. Victors, Yolanda T. Chong, Imran S. Haque, Adeline S. Low, Christopher C. Gibson.  (2020)  Identification of potential treatments for COVID-19 through artificial intelligence-enabled phenomic analysis of human cells infected with SARS-CoV-2,  [10.1101/2020.04.21.054387]
105. Dai H, Ge S, Li G, Chen J, Shi Y, Ye L, Ling Y..  (2016)  Synthesis and bioactivities of novel pyrazole oxime derivatives containing a 1,2,3-thiadiazole moiety.,  26  (18): [PMID:27503679] [10.1016/j.bmcl.2016.07.068]
106. Maria Kuzikov, Elisa Costanzi, Jeanette Reinshagen, Francesca Esposito, Laura Vangeel, Markus Wolf, Bernhard Ellinger, Carsten Claussen, Gerd Geisslinger, Angela Corona, Daniela Iaconis, Carmine Talarico, Candida Manelfi, Rolando Cannalire, Giulia Rossetti, Jonas Gossen, Simone Albani, Francesco Musiani, Katja Herzog, Yang Ye, Barbara Giabbai, Nicola Demitri, Dirk Jochmans, Steven De Jonghe, Jasper Rymenants, Vincenzo Summa, Enzo Tramontano, Andrea R. Beccari, Pieter Leyssen, Paola Storici, Johan Neyts, Philip Gribbon, and Andrea Zaliani.  (2020)  Identification of inhibitors of SARS-Cov2 M-Pro enzymatic activity using a small molecule repurposing screen,  [10.6019/CHEMBL4495564]
107. Maria Kuzikov, Elisa Costanzi, Jeanette Reinshagen, Francesca Esposito, Laura Vangeel, Markus Wolf, Bernhard Ellinger, Carsten Claussen, Gerd Geisslinger, Angela Corona, Daniela Iaconis, Carmine Talarico, Candida Manelfi, Rolando Cannalire, Giulia Rossetti, Jonas Gossen, Simone Albani, Francesco Musiani, Katja Herzog, Yang Ye, Barbara Giabbai, Nicola Demitri, Dirk Jochmans, Steven De Jonghe, Jasper Rymenants, Vincenzo Summa, Enzo Tramontano, Andrea R. Beccari, Pieter Leyssen, Paola Storici, Johan Neyts, Philip Gribbon, and Andrea Zaliani.  (2020)  Identification of inhibitors of SARS-Cov2 M-Pro enzymatic activity using a small molecule repurposing screen,  [10.6019/CHEMBL4495564]
108. Andrea Zaliani, Laura Vangeel, Jeanette Reinshagen, Daniela Iaconis, Maria Kuzikov, Oliver Keminer, Markus Wolf, Bernhard Ellinger, Francesca Esposito, Angela Corona, Enzo Tramontano, Candida Manelfi, Katja Herzog, Dirk Jochmans, Steven De Jonghe, Winston Chiu, Thibault Francken, Joost Schepers, Caroline Collard, Kayvan Abbasi, Carsten Claussen , Vincenzo Summa, Andrea R. Beccari, Johan Neyts, Philip Gribbon and Pieter Leyssen.  (2020)  Cytopathic SARS-Cov2 screening on VERO-E6 cells in a large repurposing effort,  [10.6019/CHEMBL4495565]
109. Andrea Zaliani, Laura Vangeel, Jeanette Reinshagen, Daniela Iaconis, Maria Kuzikov, Oliver Keminer, Markus Wolf, Bernhard Ellinger, Francesca Esposito, Angela Corona, Enzo Tramontano, Candida Manelfi, Katja Herzog, Dirk Jochmans, Steven De Jonghe, Winston Chiu, Thibault Francken, Joost Schepers, Caroline Collard, Kayvan Abbasi, Carsten Claussen , Vincenzo Summa, Andrea R. Beccari, Johan Neyts, Philip Gribbon and Pieter Leyssen.  (2020)  Cytopathic SARS-Cov2 screening on VERO-E6 cells in a large repurposing effort,  [10.6019/CHEMBL4495565]
110. Ellen Van Damme.  (2021)  Screening of ~5500 FDA-approved drugs and clinical candidates for anti-SARS-CoV-2 activity,  [10.6019/CHEMBL4651402]
111. Bernhard Ellinger, Justus Dick, Vanessa Lage-Rupprecht, Bruce Schultz, Andrea Zaliani, Marcin Namysl, Stephan Gebel, Ole Pless, Jeanette Reinshagen, Christian Ebeling, Alexander Esser, Marc Jacobs, Carsten Claussen, and Martin Hofmann-Apitius.  (2021)  HDAC6 screening dataset using tau-based substrate in an enzymatic assay yields selective inhibitors and activators,  [10.6019/CHEMBL4808148]
112. Ahmad S, Alam O, Naim MJ, Shaquiquzzaman M, Alam MM, Iqbal M..  (2018)  Pyrrole: An insight into recent pharmacological advances with structure activity relationship.,  157  [PMID:30119011] [10.1016/j.ejmech.2018.08.002]