Orange juice

ID: ALA4297251

Max Phase: Preclinical

Alternative Forms

1. Parent:

   

   ALA4297251

   ORANGE JUICE

Molecule Features

Natural Product: No

Oral: No

Chemical Probe: No

Parenteral: No

Molecule Type: Unknown

Topical: No

First In Class: No

Black Box: No

Chirality: No

Availability: No

Prodrug: No

Calculated Properties

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HBD:

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HBD (Lipinski):

#RO5 Violations (Lipinski):

CX Acidic pKa:

CX Basic pKa:

CX LogP:

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Np Likeness Score:

References

1. Satoh H, Yamashita F, Tsujimoto M, Murakami H, Koyabu N, Ohtani H, Sawada Y..  (2005)  Citrus juices inhibit the function of human organic anion-transporting polypeptide OATP-B.,  33  (1): [PMID:15640378] [10.1124/dmd.104.002337]

2. Dresser GK, Bailey DG, Leake BF, Schwarz UI, Dawson PA, Freeman DJ, Kim RB..  (2002)  Fruit juices inhibit organic anion transporting polypeptide-mediated drug uptake to decrease the oral availability of fexofenadine.,  71  (1): [PMID:11823753] [10.1067/mcp.2002.121152]

3. Unpublished dataset, 

Source

Source(2):

• Clinical Candidates
• TP-search Transporter Database