NYSTATIN

ID: ALA450895

Max Phase: Approved

First Approval: 1964

Molecular Formula: C47H75NO17

Molecular Weight: 926.11

Molecule Type: Small molecule

Associated Items:

Representations

Synonyms (6): L-nystatin | Mikostatin | Nystatin | Nystatinum | Terrastatin | NSC-150817
Synonyms from Alternative Forms(6):

    Trade Names(18): Barstatin 100 | Candex | Infestat | Korostatin | Multilind | Myco 20 | Mycostatin | Mykinac | Nilstat | Nysert | Nyspes | Nystaform | Nystan triple pack | Nystatin | Nystavescent | Nystex | Nystop | Tinaderm m

    Canonical SMILES:  C[C@@H]1[C@H](O)[C@@H](C)/C=C/C=C/CC/C=C/C=C/C=C/C=C/[C@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](N)[C@@H]2O)C[C@@H]2O[C@](O)(C[C@@H](O)[C@H](O)CC[C@@H](O)C[C@@H](O)C[C@@H](O)CC(=O)O[C@H]1C)C[C@H](O)[C@H]2C(=O)O

    Standard InChI:  InChI=1S/C47H75NO17/c1-27-17-15-13-11-9-7-5-6-8-10-12-14-16-18-34(64-46-44(58)41(48)43(57)30(4)63-46)24-38-40(45(59)60)37(54)26-47(61,65-38)25-36(53)35(52)20-19-31(49)21-32(50)22-33(51)23-39(55)62-29(3)28(2)42(27)56/h5-6,8,10-18,27-38,40-44,46,49-54,56-58,61H,7,9,19-26,48H2,1-4H3,(H,59,60)/b6-5+,10-8+,13-11+,14-12+,17-15+,18-16+/t27-,28-,29-,30+,31+,32+,33+,34-,35+,36+,37-,38-,40+,41-,42+,43+,44-,46-,47+/m0/s1

    Standard InChI Key:  VQOXZBDYSJBXMA-NQTDYLQESA-N

    Associated Targets(Human)

    MRC5 (9203 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    A2780 (11979 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    ABCC2 Tchem Canalicular multispecific organic anion transporter 1 (1191 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    ACHE Tclin Acetylcholinesterase (18204 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    ADORA1 Tclin Adenosine A1 receptor (17603 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    ADORA2A Tclin Adenosine A2a receptor (16305 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    ADORA3 Tchem Adenosine A3 receptor (15931 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    ADRA1D Tclin Alpha-1d adrenergic receptor (4171 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    ADRA2A Tclin Alpha-2a adrenergic receptor (9450 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    ADRA2B Tclin Alpha-2b adrenergic receptor (4412 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    ADRA2C Tclin Alpha-2c adrenergic receptor (4876 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    ADRB1 Tclin Beta-1 adrenergic receptor (6630 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    ADRB2 Tclin Beta-2 adrenergic receptor (11824 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    ADRB3 Tclin Beta-3 adrenergic receptor (5850 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    SLC6A2 Tclin Norepinephrine transporter (10102 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    AGTR2 Tchem Angiotensin II type 2 (AT-2) receptor (2549 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    BDKRB2 Tclin Bradykinin B2 receptor (3970 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    CALCR Tclin Calcitonin receptor (2215 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    CNR1 Tclin Cannabinoid CB1 receptor (20913 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    CA2 Tclin Carbonic anhydrase II (17698 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    CCR2 Tchem C-C chemokine receptor type 2 (5628 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    CCR4 Tclin C-C chemokine receptor type 4 (2819 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    CCR5 Tclin C-C chemokine receptor type 5 (5640 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    CXCR1 Tchem Interleukin-8 receptor A (2256 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    CXCR2 Tchem Interleukin-8 receptor B (3491 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    CCKAR Tclin Cholecystokinin A receptor (4460 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    PTGS1 Tclin Cyclooxygenase-1 (9233 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    PTGS2 Tclin Cyclooxygenase-2 (13999 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    CYP1A2 Tchem Cytochrome P450 1A2 (26471 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    CYP2A6 Tchem Cytochrome P450 2A6 (2861 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    CYP2C19 Tchem Cytochrome P450 2C19 (29246 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    CYP2C9 Tchem Cytochrome P450 2C9 (32119 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    CYP2D6 Tclin Cytochrome P450 2D6 (33882 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    CYP2E1 Tchem Cytochrome P450 2E1 (2174 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    CYP3A4 Tclin Cytochrome P450 3A4 (53859 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    DRD1 Tclin Dopamine D1 receptor (9720 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    DRD2 Tclin Dopamine D2 receptor (23596 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    DRD3 Tclin Dopamine D3 receptor (14368 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    DRD4 Tchem Dopamine D4 receptor (7907 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    SLC6A3 Tclin Dopamine transporter (10535 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    EDNRA Tclin Endothelin receptor ET-A (5008 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    ESR1 Tclin Estrogen receptor alpha (17718 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    ESR2 Tclin Estrogen receptor beta (9272 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    NR3C1 Tclin Glucocorticoid receptor (14987 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    HRH1 Tclin Histamine H1 receptor (7573 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    HRH2 Tclin Histamine H2 receptor (5428 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    HMGCR Tclin HMG-CoA reductase (2475 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    CYSLTR1 Tclin Cysteinyl leukotriene receptor 1 (2118 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    MC3R Tchem Melanocortin receptor 3 (5659 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    MC4R Tclin Melanocortin receptor 4 (10016 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    MC5R Tchem Melanocortin receptor 5 (4283 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    MAOA Tclin Monoamine oxidase A (11911 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    CHRM1 Tclin Muscarinic acetylcholine receptor M1 (12690 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    CHRM2 Tclin Muscarinic acetylcholine receptor M2 (10671 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    CHRM3 Tclin Muscarinic acetylcholine receptor M3 (7750 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    CHRM4 Tclin Muscarinic acetylcholine receptor M4 (6041 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    CHRM5 Tclin Muscarinic acetylcholine receptor M5 (4677 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    NPY1R Tchem Neuropeptide Y receptor type 1 (5019 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    NPY2R Tchem Neuropeptide Y receptor type 2 (3731 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    OPRD1 Tclin Delta opioid receptor (15096 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    OPRK1 Tclin Kappa opioid receptor (16155 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    OPRM1 Tclin Mu opioid receptor (19785 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    PDE5A Tclin Phosphodiesterase 5A (5113 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    PTAFR Tchem Platelet activating factor receptor (2575 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    KCNH2 Tclin HERG (29587 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    CASP1 Tchem Caspase-1 (6235 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    CTSG Tchem Cathepsin G (2304 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    ELANE Tclin Leukocyte elastase (8173 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    MMP1 Tchem Matrix metalloproteinase-1 (7046 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    MMP9 Tchem Matrix metalloproteinase 9 (6779 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    PRKCA Tchem Protein kinase C alpha (5923 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    MAPK3 Tchem MAP kinase ERK1 (4725 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    MAPK1 Tchem MAP kinase ERK2 (25055 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    MAPK14 Tchem MAP kinase p38 alpha (12866 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    PPP3CA Tchem Serine/threonine protein phosphatase 2B catalytic subunit, alpha isoform (1831 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    EGFR Tclin Epidermal growth factor receptor erbB1 (33727 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    FYN Tclin Tyrosine-protein kinase FYN (5308 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    ERBB2 Tclin Receptor protein-tyrosine kinase erbB-2 (7851 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    LCK Tclin Tyrosine-protein kinase LCK (9212 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    PTPRC Tchem Leukocyte common antigen (2317 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    HTR2A Tclin Serotonin 2a (5-HT2a) receptor (14758 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    HTR2B Tclin Serotonin 2b (5-HT2b) receptor (10323 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    HTR2C Tclin Serotonin 2c (5-HT2c) receptor (11471 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    HTR6 Tchem Serotonin 6 (5-HT6) receptor (9749 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    SLC6A4 Tclin Serotonin transporter (12625 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    SIGMAR1 Tclin Sigma opioid receptor (6358 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    TACR1 Tclin Neurokinin 1 receptor (6273 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    TACR2 Tchem Neurokinin 2 receptor (3341 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    TBXAS1 Tchem Thromboxane-A synthase (3355 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    FLT1 Tclin Vascular endothelial growth factor receptor 1 (6262 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    VIPR1 Tchem Vasoactive intestinal polypeptide receptor 1 (1904 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    AVPR1A Tclin Vasopressin V1a receptor (5412 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    SLCO2B1 Tchem Solute carrier organic anion transporter family member 2B1 (580 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    SLCO1B3 Tchem Solute carrier organic anion transporter family member 1B3 (2517 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    SLCO1B1 Tchem Solute carrier organic anion transporter family member 1B1 (2672 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Homo sapiens (32628 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    HDAC6 Tclin Histone deacetylase 6 (20808 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    HEp-2 (3859 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    ABCB11 Tchem Bile salt export pump (2311 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    HTR1A Tclin Serotonin 1a (5-HT1a) receptor (14969 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    PDE3A Tclin Phosphodiesterase 3A (3309 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    F2 Tclin Thrombin (11687 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    TBXA2R Tclin Thromboxane A2 receptor (5717 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    HRH3 Tclin Histamine H3 receptor (10389 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    AR Tclin Androgen Receptor (11781 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    PGR Tclin Progesterone receptor (8562 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    PDE4A Tclin Phosphodiesterase 4A (1943 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    ADRA1A Tclin Alpha-1a adrenergic receptor (8359 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

    Associated Targets(non-human)

    Candida albicans (78123 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Cryptococcus neoformans (21258 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Trichophyton benhamiae (1686 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Aspergillus fumigatus (16427 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Microsporum canis (872 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Penicillium citrinum (522 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Fusarium solani (1274 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Saccharomyces cerevisiae (19171 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Tolypocladium inflatum (13 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Candida parapsilosis (8521 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Candida tropicalis (8381 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Kluyveromyces marxianus (909 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Diutina rugosa (288 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Aspergillus niger (16508 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Trichophyton rubrum (3646 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Mucor fragilis (36 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Aspergillus flavus (8875 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Nannizzia gypsea (2039 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Sporothrix schenckii (1580 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Histoplasma capsulatum (403 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Cephalosporium (5 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Fusarium verticillioides (912 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Pichia kudriavzevii (7448 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Trichoderma (92 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Fusarium oxysporum (3998 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Salmonella enteritidis (727 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Escherichia coli (133304 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Bacillus subtilis (32866 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Staphylococcus aureus (210822 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Botrytis cinerea (4183 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Nakaseomyces glabratus (9108 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Rhodotorula mucilaginosa (339 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Hanseniaspora guilliermondii (39 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Debaryomyces hansenii (127 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Cladosporium herbarum (157 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Plenodomus lingam (178 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Cladosporium cladosporioides (101 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Cladosporium sphaerospermum (47 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Candida (1648 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Penicillium expansum (70 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Trichophyton mentagrophytes (4846 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Fusarium subglutinans (7 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Pichia kluyveri (24 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Cladosporium cucumerinum (320 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    M109 (194 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Fusarium avenaceum (92 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Bipolaris maydis (114 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Talaromyces islandicus (6 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Ophiostoma minus (6 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Trichoderma viride (1263 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Penicillium sp. (198 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Helminthosporium (185 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    BK polyomavirus (44 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Enterococcus durans (113 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Amorphotheca resinae (75 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Alternaria alternata (757 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Alternaria citri (70 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Ascochyta rabiei (17 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Aspergillus parasiticus (296 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Colletotrichum gloeosporioides (560 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Fusarium acuminatum (10 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Fusarium graminearum (1554 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Fusarium oxysporum f. sp. lycopersici (29 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Fusarium incarnatum (10 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Plenodomus tracheiphilus (3 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Penicillium verrucosum (38 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Penicillium brevicompactum (15 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Meyerozyma guilliermondii (575 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Candida maltosa (58 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Kluyveromyces lactis (70 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Wickerhamomyces anomalus (305 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Starmera dryadoides (3 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Yarrowia lipolytica (267 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Fusarium tricinctum (47 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Colletotrichum graminicola (112 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Epidermophyton floccosum (561 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Paecilomyces (2 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    [Chlorella] fusca (158 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Microbotryum violaceum (192 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Priestia megaterium (1154 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Macrophomina phaseolina (474 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Fusarium equiseti (38 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Aspergillus ochraceus (560 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Penicillium chrysogenum (1593 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Proteus vulgaris (5823 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Klebsiella pneumoniae (43867 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Bacillus anthracis (2936 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Geobacillus stearothermophilus (181 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Bacillus cereus (7522 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Pseudomonas fluorescens (1630 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Shigella dysenteriae (933 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Pseudomonas aeruginosa (123386 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Salmonella enterica (1497 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Citrobacter freundii (1864 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Microsporum audouinii (120 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Penicillium (212 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Serratia marcescens (3237 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Staphylococcus epidermidis (22802 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Enterococcus faecium (13803 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Trueperella pyogenes (62 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Micrococcus luteus (7463 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Aspergillus sp. (177 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Curvularia (47 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Fusarium sp. (88 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Paecilomyces variotii (130 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Talaromyces marneffei (1157 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    ABC1 ATP binding cassette transporter Abc1p (50 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Trichosporon beigelii (253 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Lichtheimia corymbifera (940 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Legionella pneumophila (143 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Clostridium tetani (653 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Streptococcus pneumoniae (31063 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Salmonella typhi (4293 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Vibrio cholerae (1211 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Aspergillus clavatus (1299 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Adra1a Alpha-1a adrenergic receptor (3346 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Adra1b Alpha-1b adrenergic receptor (2470 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Akr1b1 Aldose reductase (4007 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Glra2 Glycine receptor (1745 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Insr Insulin receptor (1750 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    LTC4S Leukotriene C4 synthase (1746 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    ALOX15 Arachidonate 15-lipoxygenase (2064 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Nos1 Nitric-oxide synthase, brain (2987 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Nos2 Nitric oxide synthase, inducible (3573 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    PGR Progesterone receptor (1742 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    ACE Angiotensin-converting enzyme (2863 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Htr1a Serotonin 1a (5-HT1a) receptor (8655 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Htr1b Serotonin 1b (5-HT1b) receptor (2343 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    HTR4 Serotonin 4 (5-HT4) receptor (2870 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Ar Androgen Receptor (5522 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Yamadazyma tenuis (183 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Mycobacterium (258 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Mucor hiemalis (184 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Schizosaccharomyces pombe (495 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Rhodotorula glutinis (200 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    [Candida] aaseri (85 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Salmonella typhimurium (15756 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Enterococcus faecalis (29875 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Klebsiella aerogenes (4963 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Pyricularia oryzae (1832 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Trichophyton verrucosum (23 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Fusarium culmorum (260 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Aspergillus sydowii (55 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Streptococcus pyogenes (16140 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Curvularia lunata (722 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Alternaria (24 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    [Candida] sake (415 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Rhizoctonia solani (2251 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Eremothecium coryli (20 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Fusarium oxysporum f. sp. niveum (47 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Pichia membranifaciens (35 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Cyberlindnera jadinii (900 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Fusarium oxysporum f. sp. cubense (9 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Aspergillus brasiliensis (162 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Lactococcus lactis (206 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Pseudoperonospora cubensis (1623 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Podosphaera fuliginea (1057 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Phytophthora infestans (820 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Rattus norvegicus (775804 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Mucor plumbeus (22 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Streptococcus mutans (2687 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Bacillus flexus (54 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Clostridium sporogenes (139 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Pseudomonas sp. (174 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Aspergillus terreus (892 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Sclerotinia sclerotiorum (877 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    SARS-CoV-2 (38078 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Trichoderma harzianum (66 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    rep Replicase polyprotein 1ab (11336 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Ustilago maydis (75 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Penicillium italicum (133 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
    Gabra1 GABA receptor alpha-1 subunit (2848 Activities)
    Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

    Molecule Features

    Natural Product: NoOral: YesChemical Probe: NoParenteral: No
    Molecule Type: Small moleculeTopical: YesFirst In Class: NoBlack Box: No
    Chirality: YesAvailability: YesProdrug: No

    Drug Indications

    MESH IDMESH Heading EFO IDsEFO TermsMax Phase for IndicationReferences

    Mechanisms of Action

    Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

    Properties

    Molecular Weight: 926.11Molecular Weight (Monoisotopic): 925.5035AlogP: 0.94#Rotatable Bonds: 3
    Polar Surface Area: 319.61Molecular Species: ZWITTERIONHBA: 17HBD: 12
    #RO5 Violations: 3HBA (Lipinski): 18HBD (Lipinski): 13#RO5 Violations (Lipinski): 3
    CX Acidic pKa: 3.72CX Basic pKa: 9.11CX LogP: -1.94CX LogD: -1.94
    Aromatic Rings: 0Heavy Atoms: 65QED Weighted: 0.18Np Likeness Score: 1.80

    References

    1. Tandon VK, Chhor RB, Singh RV, Rai S, Yadav DB..  (2004)  Design, synthesis and evaluation of novel 1,4-naphthoquinone derivatives as antifungal and anticancer agents.,  14  (5): [PMID:14980639] [10.1016/j.bmcl.2004.01.002]
    2. Reich MF, Fabio PF, Lee VJ, Kuck NA, Testa RT..  (1989)  Pyrido[3,4-e]-1,2,4-triazines and related heterocycles as potential antifungal agents.,  32  (11): [PMID:2810336] [10.1021/jm00131a010]
    3. Uchiro H, Nagasawa K, Sawa T, Hasegawa D, Kotake T, Sugiura Y, Kobayashi S, Otoguro K, Omura S..  (2002)  Remarkable influence of the aromatic substructure in 9-methoxystrobilurin derivatives on their antifungal activity.,  12  (19): [PMID:12217357] [10.1016/s0960-894x(02)00558-9]
    4. Aiba Y, Hasegawa D, Marunouchi T, Nagasawa K, Uchiro H, Kobayashi S..  (2001)  Total synthesis and antifungal activity of 9-methoxystrobilurin L as the originally proposed 1,4-benzodioxan structure.,  11  (20): [PMID:11591523] [10.1016/s0960-894x(01)00561-3]
    5. Uchiro H, Nagasawa K, Kotake T, Hasegawa D, Tomita A, Kobayashi S..  (2002)  The first synthesis and antifungal activities of 9-methoxystrobilurin-type beta-substituted beta-methoxyacrylate.,  12  (20): [PMID:12270154] [10.1016/s0960-894x(02)00625-x]
    6. Tandon VK, Singh RV, Yadav DB..  (2004)  Synthesis and evaluation of novel 1,4-naphthoquinone derivatives as antiviral, antifungal and anticancer agents.,  14  (11): [PMID:15125956] [10.1016/j.bmcl.2004.03.047]
    7. Hazra B, Pore V, Dey S, Datta S, Darokar M, Saikia D, Khanuja SP, Thakur A..  (2004)  Bile acid amides derived from chiral amino alcohols: novel antimicrobials and antifungals.,  14  (3): [PMID:14741287] [10.1016/j.bmcl.2003.11.018]
    8. Sadashiva MP, Mallesha H, Karunakara Murthy K, Rangappa KS..  (2005)  Enhancement in antimicrobial activity of 2-(phenyl)-3-(2-butyl-4-chloro-1H-imidazolyl)-5-butylate isoxazolidine.,  15  (7): [PMID:15780612] [10.1016/j.bmcl.2005.02.034]
    9. Tandon VK, Yadav DB, Chaturvedi AK, Shukla PK..  (2005)  Synthesis of (1,4)-naphthoquinono-[3,2-c]-1H-pyrazoles and their (1,4)-naphthohydroquinone derivatives as antifungal, antibacterial, and anticancer agents.,  15  (13): [PMID:15913995] [10.1016/j.bmcl.2005.04.066]
    10. Tandon VK, Yadav DB, Singh RV, Chaturvedi AK, Shukla PK..  (2005)  Synthesis and biological evaluation of novel (L)-alpha-amino acid methyl ester, heteroalkyl, and aryl substituted 1,4-naphthoquinone derivatives as antifungal and antibacterial agents.,  15  (23): [PMID:16202590] [10.1016/j.bmcl.2005.08.032]
    11. Nanjunda Swamy S, Basappa, Sarala G, Priya BS, Gaonkar SL, Shashidhara Prasad J, Rangappa KS..  (2006)  Microwave-assisted synthesis of N-alkylated benzotriazole derivatives: antimicrobial studies.,  16  (4): [PMID:16298529] [10.1016/j.bmcl.2005.10.084]
    12. Macreadie P, Avery T, Greatrex B, Taylor D, Macreadie I..  (2006)  Novel endoperoxides: synthesis and activity against Candida species.,  16  (4): [PMID:16297620] [10.1016/j.bmcl.2005.10.101]
    13. Yang RY, Li CY, Lin YC, Peng GT, She ZG, Zhou SN..  (2006)  Lactones from a brown alga endophytic fungus (No. ZZF36) from the South China Sea and their antimicrobial activities.,  16  (16): [PMID:16781152] [10.1016/j.bmcl.2006.05.081]
    14. El-Seedi HR..  (2007)  Antimicrobial arylcoumarins from Asphodelus microcarpus.,  70  (1): [PMID:17253862] [10.1021/np060444u]
    15. Kotharkar SA, Shinde DB..  (2006)  Synthesis of antimicrobial 2,9,10-trisubstituted-6-oxo-7,12-dihydro-chromeno[3,4-b]quinoxalines.,  16  (24): [PMID:17027265] [10.1016/j.bmcl.2006.09.040]
    16. Vandeputte P, Tronchin G, Bergès T, Hennequin C, Chabasse D, Bouchara JP..  (2007)  Reduced susceptibility to polyenes associated with a missense mutation in the ERG6 gene in a clinical isolate of Candida glabrata with pseudohyphal growth.,  51  (3): [PMID:17158937] [10.1128/aac.01510-06]
    17. Avery TD, Macreadie PI, Greatrex BW, Robinson TV, Taylor DK, Macreadie IG..  (2007)  Design of endoperoxides with anti-Candida activity.,  15  (1): [PMID:17079152] [10.1016/j.bmc.2006.10.021]
    18. Aghatabay NM, Neshat A, Karabiyik T, Somer M, Haciu D, Dülger B..  (2007)  Synthesis, characterization and antimicrobial activity of Fe(II), Zn(II), Cd(II) and Hg(II) complexes with 2,6-bis(benzimidazol-2-yl) pyridine ligand.,  42  (2): [PMID:17189664] [10.1016/j.ejmech.2006.09.023]
    19. Mohamed NR, El-Saidi MM, Ali YM, Elnagdi MH..  (2007)  Utility of 6-amino-2-thiouracil as a precursor for the synthesis of bioactive pyrimidine derivatives.,  15  (18): [PMID:17600721] [10.1016/j.bmc.2007.06.023]
    20. Aghatabay NM, Somer M, Senel M, Dulger B, Gucin F..  (2007)  Raman, FT-IR, NMR spectroscopic data and antimicrobial activity of bis[micro2-(benzimidazol-2-yl)-2-ethanethiolato-N,S,S-chloro-palladium(II)] dimer, [(micro2-CH2CH2NHNCC6H4)PdCl]2.C2H5OH complex.,  42  (8): [PMID:17350734] [10.1016/j.ejmech.2007.01.011]
    21. Schmidt LE, Gloer JB, Wicklow DT..  (2007)  Solanapyrone analogues from a Hawaiian fungicolous fungus.,  70  (8): [PMID:17663585] [10.1021/np070251m]
    22. Kokubun T, Rozwadowski Z, Duddeck H..  (2007)  Benzaldehyde derivatives from Sarcodontia crocea.,  70  (9): [PMID:17822300] [10.1021/np070305s]
    23. Mencherini T, Picerno P, Scesa C, Aquino R..  (2007)  Triterpene, antioxidant, and antimicrobial compounds from Melissa officinalis.,  70  (12): [PMID:18004816] [10.1021/np070351s]
    24. Marques JV, Kitamura RO, Lago JH, Young MC, Guimarães EF, Kato MJ..  (2007)  Antifungal amides from Piper scutifolium and Piper hoffmanseggianum.,  70  (12): [PMID:18031016] [10.1021/np070347g]
    25. de Aquino TM, Liesen AP, da Silva RE, Lima VT, Carvalho CS, de Faria AR, de Araújo JM, de Lima JG, Alves AJ, de Melo EJ, Góes AJ..  (2008)  Synthesis, anti-Toxoplasma gondii and antimicrobial activities of benzaldehyde 4-phenyl-3-thiosemicarbazones and 2-[(phenylmethylene)hydrazono]-4-oxo-3-phenyl-5-thiazolidineacetic acids.,  16  (1): [PMID:17905587] [10.1016/j.bmc.2007.09.025]
    26. El-Gazzar AR, El-Enany MM, Mahmoud MN..  (2008)  Synthesis, analgesic, anti-inflammatory, and antimicrobial activity of some novel pyrimido[4,5-b]quinolin-4-ones.,  16  (6): [PMID:18158248] [10.1016/j.bmc.2007.12.012]
    27. Necula M, Kayed R, Milton S, Glabe CG..  (2007)  Small molecule inhibitors of aggregation indicate that amyloid beta oligomerization and fibrillization pathways are independent and distinct.,  282  (14): [PMID:17284452] [10.1074/jbc.m608207200]
    28. Altomare C, Perrone G, Zonno MC, Evidente A, Pengue R, Fanti F, Polonelli L..  (2000)  Biological characterization of fusapyrone and deoxyfusapyrone, two bioactive secondary metabolites of Fusarium semitectum.,  63  (8): [PMID:10978211] [10.1021/np000023r]
    29. Brady SF, Clardy J..  (2000)  CR377, a new pentaketide antifungal agent isolated from an endophytic fungus.,  63  (10): [PMID:11076576] [10.1021/np990568p]
    30. Soman AG, Gloer JB, Wicklow DT..  (1999)  Antifungal and antibacterial metabolites from a sclerotium-colonizing isolate of Mortierella vinacea.,  62  (2): [PMID:10075797] [10.1021/np980411h]
    31. Ashour M, Edrada R, Ebel R, Wray V, Wätjen W, Padmakumar K, Müller WE, Lin WH, Proksch P..  (2006)  Kahalalide derivatives from the Indian sacoglossan mollusk Elysia grandifolia.,  69  (11): [PMID:17125219] [10.1021/np060172v]
    32. González M, Zamilpa A, Marquina S, Navarro V, Alvarez L..  (2004)  Antimycotic spirostanol saponins from Solanum hispidum leaves and their structure-activity relationships.,  67  (6): [PMID:15217270] [10.1021/np0305019]
    33. Lee JY, Moon SS, Yun BS, Yoo ID, Hwang BK..  (2004)  Thiobutacin, a novel antifungal and antioomycete antibiotic from Lechevalieria aerocolonigenes.,  67  (12): [PMID:15620255] [10.1021/np049786v]
    34. Reynolds WF, Yu M, Enriquez RG, Gonzalez H, Leon I, Magos G, Villareal ML..  (1995)  Isolation and characterization of cytotoxic and antibacterial tetrasaccharide glycosides from Ipomoea stans.,  58  (11): [PMID:8594150] [10.1021/np50125a014]
    35. Ioset JR, Marston A, Gupta MP, Hostettmann K..  (2001)  Five new prenylated stilbenes from the root bark of Lonchocarpus chiricanus.,  64  (6): [PMID:11421729] [10.1021/np000597w]
    36. Zhang W, Krohn K, Draeger S, Schulz B..  (2008)  Bioactive isocoumarins isolated from the endophytic fungus Microdochium bolleyi.,  71  (6): [PMID:18510362] [10.1021/np800095g]
    37. Aghatabay NM, Mahmiani Y, Cevik H, Dulger B..  (2009)  Synthesis, Raman, FT-IR, NMR spectroscopic data and antimicrobial activity of mixed aza-oxo-thia macrocyclic compounds.,  44  (1): [PMID:18417256] [10.1016/j.ejmech.2008.02.038]
    38. Manjula MK, Rai KM, Gaonkar SL, Raveesha KA, Satish S..  (2009)  Synthesis of new series of 5,6-dihydro-4H-1,2-oxazines via hetero Diels-Alder reaction and evaluation of antimicrobial activity.,  44  (1): [PMID:18420309] [10.1016/j.ejmech.2008.02.027]
    39. Tandon VK, Maurya HK, Tripathi A, ShivaKeshava GB, Shukla PK, Srivastava P, Panda D..  (2009)  2,3-Disubstituted-1,4-naphthoquinones, 12H-benzo[b]phenothiazine-6,11-diones and related compounds: synthesis and biological evaluation as potential antiproliferative and antifungal agents.,  44  (3): [PMID:18708272] [10.1016/j.ejmech.2008.06.025]
    40. Fouad M, Edrada RA, Ebel R, Wray V, Müller WE, Lin WH, Proksch P..  (2006)  Cytotoxic isomalabaricane triterpenes from the marine sponge Rhabdastrella globostellata.,  69  (2): [PMID:16499318] [10.1021/np050346t]
    41. Valsaraj R, Pushpangadan P, Smitt UW, Adsersen A, Christensen SB, Sittie A, Nyman U, Nielsen C, Olsen CE..  (1997)  New anti-HIV-1, antimalarial, and antifungal compounds from Terminalia bellerica.,  60  (7): [PMID:9249982] [10.1021/np970010m]
    42. Zamilpa A, Tortoriello J, Navarro V, Delgado G, Alvarez L..  (2002)  Five new steroidal saponins from Solanum chrysotrichum leaves and their antimycotic activity.,  65  (12): [PMID:12502320] [10.1021/np020261h]
    43. Wagenaar MM, Clardy J..  (2001)  Dicerandrols, new antibiotic and cytotoxic dimers produced by the fungus Phomopsis longicolla isolated from an endangered mint.,  64  (8): [PMID:11520215] [10.1021/np010020u]
    44. Smejkal K, Chudík S, Kloucek P, Marek R, Cvacka J, Urbanová M, Julínek O, Kokoska L, Slapetová T, Holubová P, Zima A, Dvorská M..  (2008)  Antibacterial C-geranylflavonoids from Paulownia tomentosa Fruits.,  71  (4): [PMID:18293924] [10.1021/np070446u]
    45. Butnariu RM, Mangalagiu II..  (2009)  New pyridazine derivatives: synthesis, chemistry and biological activity.,  17  (7): [PMID:19272782] [10.1016/j.bmc.2009.02.028]
    46. Saxena G, Farmer SW, Hancock RE, Towers GH..  (1996)  Chlorochimaphilin: a new antibiotic from Moneses uniflora.,  59  (1): [PMID:8984155] [10.1021/np960006v]
    47. Wächter GA, Matooq G, Hoffmann JJ, Maiese WM, Singh MP, Montenegro G, Timmermann BN..  (1999)  Antibacterial diterpenoid acids from Azorella compacta.,  62  (9): [PMID:10514324] [10.1021/np990134u]
    48. Guiraud P, Steiman R, Seigle-Murandi F, Buarque De Gusmao N..  (1999)  Antimicrobial and antitumor activities of mycosporulone.,  62  (9): [PMID:10514301] [10.1021/np9805084]
    49. Aljancić I, Vajs V, Menković N, Karadzić I, Juranić N, Milosavljević S, Macura S..  (1999)  Flavones and sesquiterpene lactones from Achillea atrata subsp. multifida: antimicrobial activity.,  62  (6): [PMID:10395518] [10.1021/np980536m]
    50. Young MC, Araújo AR, da Silva CA, Lopes MN, Trevisan LM, Bolzani VS..  (1998)  Triterpenes and saponins from Rudgea viburnioides.,  61  (7): [PMID:9677278] [10.1021/np9704617]
    51. Grosvenor PW, Gray DO..  (1998)  Coluteol and Colutequinone B, More Antifungal Isoflavonoids from Colutea arborescens,  61  (1): [PMID:9548836] [10.1021/np9703205]
    52. Elkhayat E, Edrada R, Ebel R, Wray V, van Soest R, Wiryowidagdo S, Mohamed MH, Müller WE, Proksch P..  (2004)  New luffariellolide derivatives from the Indonesian sponge Acanthodendrilla sp.,  67  (11): [PMID:15568767] [10.1021/np040118j]
    53. Kossuga MH, MacMillan JB, Rogers EW, Molinski TF, Nascimento GG, Rocha RM, Berlinck RG..  (2004)  (2S,3R)-2-aminododecan-3-ol, a new antifungal agent from the ascidian Clavelina oblonga.,  67  (11): [PMID:15568780] [10.1021/np049782q]
    54. Lago JH, Ramos CS, Casanova DC, Morandim Ade A, Bergamo DC, Cavalheiro AJ, Bolzani Vda S, Furlan M, Guimarães EF, Young MC, Kato MJ..  (2004)  Benzoic acid derivatives from Piper species and their fungitoxic activity against Cladosporium cladosporioides and C. sphaerospermum.,  67  (11): [PMID:15568762] [10.1021/np030530j]
    55. Van Puyvelde L, De Kimpe N, Costa J, Munyjabo V, Nyirankuliza S, Hakizamungu E, Schamp N..  (1989)  Isolation of flavonoids and a chalcone from Helichrysum odoratissimum and synthesis of helichrysetin.,  52  (3): [PMID:2778452] [10.1021/np50063a025]
    56. Nair MG, Putnam AR, Mishra SK, Mulks MH, Taft WH, Keller JE, Miller JR, Zhu PP, Meinhart JD, Lynn DG..  (1989)  Faeriefungin: a new broad-spectrum antibiotic from Streptomyces griseus var. autotrophicus.,  52  (4): [PMID:2509636] [10.1021/np50064a022]
    57. Orabi KY, Mossa JS, el-Feraly FS..  (1991)  Isolation and characterization of two antimicrobial agents from mace (Myristica fragrans).,  54  (3): [PMID:1955885] [10.1021/np50075a017]
    58. Prinsep MR, Blunt JW, Munro MH..  (1991)  New cytotoxic beta-carboline alkaloids from the marine bryozoan, Cribricellina cribraria.,  54  (4): [PMID:1791472] [10.1021/np50076a023]
    59. Gunatilaka AA, Berger JM, Evans R, Miller JS, Wisse JH, Neddermann KM, Bursuker I, Kingston DG..  (2001)  Isolation, synthesis, and structure-activity relationships of bioactive benzoquinones from Miconia lepidota from the Suriname rainforest.,  64  (1): [PMID:11170656] [10.1021/np000219r]
    60. Pedersen JM, Matsson P, Bergström CA, Norinder U, Hoogstraate J, Artursson P..  (2008)  Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).,  51  (11): [PMID:18457386] [10.1021/jm7015683]
    61. Wu SH, Chen YW, Shao SC, Wang LD, Li ZY, Yang LY, Li SL, Huang R..  (2008)  Ten-membered lactones from Phomopsis sp., an endophytic fungus of Azadirachta indica.,  71  (4): [PMID:18336005] [10.1021/np070624j]
    62. Hafez HN, El-Gazzar AB..  (2008)  Design and synthesis of 3-pyrazolyl-thiophene, thieno[2,3-d]pyrimidines as new bioactive and pharmacological activities.,  18  (19): [PMID:18783947] [10.1016/j.bmcl.2008.08.071]
    63. Serfling A, Wohlrab J, Deising HB..  (2007)  Treatment of a clinically relevant plant-pathogenic fungus with an agricultural azole causes cross-resistance to medical azoles and potentiates caspofungin efficacy.,  51  (10): [PMID:17620378] [10.1128/aac.00654-07]
    64. Mitić D, Milenković M, Milosavljević S, Godevac D, Miodragović Z, Andelković K, Miodragović D..  (2009)  Synthesis, characterization and antimicrobial activity of Co(II), Zn(II) and Cd(II) complexes with N-benzyloxycarbonyl-S-phenylalanine.,  44  (4): [PMID:18760509] [10.1016/j.ejmech.2008.07.017]
    65. Randhawa P, Farasati NA, Huang Y..  (2007)  BK Virus replication in vitro: limited effect of drugs interfering with viral uptake and intracellular transport.,  51  (12): [PMID:17893158] [10.1128/aac.00843-07]
    66. Sharma S, Gangal S, Rauf A..  (2009)  Convenient one-pot synthesis of novel 2-substituted benzimidazoles, tetrahydrobenzimidazoles and imidazoles and evaluation of their in vitro antibacterial and antifungal activities.,  44  (4): [PMID:18472189] [10.1016/j.ejmech.2008.03.026]
    67. Balan AM, Florea O, Moldoveanu C, Zbancioc G, Iurea D, Mangalagiu II..  (2009)  Diazinium salts with dihydroxyacetophenone skeleton: Syntheses and antimicrobial activity.,  44  (5): [PMID:18672317] [10.1016/j.ejmech.2008.06.017]
    68. Ioset JR, Marston A, Gupta MP, Hostettmann K..  (2000)  Antifungal and larvicidal compounds from the root bark of Cordia alliodora.,  63  (3): [PMID:10757739] [10.1021/np990393j]
    69. Pereda-Miranda R, Hernández L, Villavicencio MJ, Novelo M, Ibarra P, Chai H, Pezzuto JM..  (1993)  Structure and stereochemistry of pectinolides A-C, novel antimicrobial and cytotoxic 5,6-dihydro-alpha-pyrones from Hyptis pectinata.,  56  (4): [PMID:8496706] [10.1021/np50094a019]
    70. Lorimer SD, Perry NB, Tangney RS..  (1993)  An antifungal bibenzyl from the New Zealand liverwort, Plagiochila stephensoniana. Bioactivity-directed isolation, synthesis, and analysis.,  56  (9): [PMID:8254344] [10.1021/np50099a002]
    71. Hamburger MO, Cordell GA, Tantivatana P, Ruangrungsi N..  (1987)  Traditional medicinal plants of Thailand, VIII. Isoflavonoids of Dalbergia candenatensis.,  50  (4): [PMID:3430167] [10.1021/np50052a020]
    72. Hussain I, Yawer MA, Lalk M, Lindequist U, Villinger A, Fischer C, Langer P..  (2008)  Hetero-Diels-Alder reaction of 1,3-bis(trimethylsilyloxy)-1,3-butadienes with arylsulfonylcyanides. Synthesis and antimicrobial activity of 4-hydroxy-2-(arylsulfonyl)pyridines.,  16  (23): [PMID:18990580] [10.1016/j.bmc.2008.10.033]
    73. Hoettecke N, Rotzoll S, Albrecht U, Lalk M, Fischer C, Langer P..  (2008)  Synthesis and antimicrobial activity of 2-alkenylchroman-4-ones, 2-alkenylthiochroman-4-ones and 2-alkenylquinol-4-ones.,  16  (24): [PMID:18977661] [10.1016/j.bmc.2008.10.043]
    74. Dias DA, Goble DJ, Silva CA, Urban S..  (2009)  Phenylphenalenones from the Australian plant Haemodorum simplex.,  72  (6): [PMID:19419186] [10.1021/np900016h]
    75. Tandon VK, Maurya HK, Mishra NN, Shukla PK..  (2009)  Design, synthesis and biological evaluation of novel nitrogen and sulfur containing hetero-1,4-naphthoquinones as potent antifungal and antibacterial agents.,  44  (8): [PMID:19349095] [10.1016/j.ejmech.2009.03.006]
    76. El-Gaby MS, El-Hag Ali GA, El-Maghraby AA, Abd El-Rahman MT, Helal MH..  (2009)  Synthesis, characterization and in vitro antimicrobial activity of novel 2-thioxo-4-thiazolidinones and 4,4'-bis(2-thioxo-4-thiazolidinone-3-yl)diphenylsulfones.,  44  (10): [PMID:19540629] [10.1016/j.ejmech.2009.05.005]
    77. Pejin B, Iodice C, Tommonaro G, De Rosa S..  (2008)  Synthesis and biological activities of thio-avarol derivatives.,  71  (11): [PMID:19007183] [10.1021/np800318m]
    78. Aghatabay NM, Baş A, Kircali A, Sen G, Yazicioğlu MB, Gücin F, Dülger B..  (2009)  Synthesis, Raman, FT-IR, NMR spectroscopic characterization, antimicrobial activity, cytotoxicity and DNA binding of new mixed aza-oxo-thia macrocyclic compounds.,  44  (11): [PMID:19700225] [10.1016/j.ejmech.2009.07.003]
    79. Hussain T, Siddiqui HL, Zia-ur-Rehman M, Masoom Yasinzai M, Parvez M..  (2009)  Anti-oxidant, anti-fungal and anti-leishmanial activities of novel 3-[4-(1H-imidazol-1-yl) phenyl]prop-2-en-1-ones.,  44  (11): [PMID:19664864] [10.1016/j.ejmech.2009.06.038]
    80. Bandgar BP, Gawande SS, Bodade RG, Gawande NM, Khobragade CN..  (2009)  Synthesis and biological evaluation of a novel series of pyrazole chalcones as anti-inflammatory, antioxidant and antimicrobial agents.,  17  (24): [PMID:19896853] [10.1016/j.bmc.2009.10.035]
    81. Ajani OO, Obafemi CA, Nwinyi OC, Akinpelu DA..  (2010)  Microwave assisted synthesis and antimicrobial activity of 2-quinoxalinone-3-hydrazone derivatives.,  18  (1): [PMID:19948407] [10.1016/j.bmc.2009.10.064]
    82. Bandgar BP, Gawande SS..  (2010)  Synthesis and biological screening of a combinatorial library of beta-chlorovinyl chalcones as anticancer, anti-inflammatory and antimicrobial agents.,  18  (5): [PMID:20138527] [10.1016/j.bmc.2009.12.077]
    83. Shamsuzzaman, Khan MS, Alam M, Tabassum Z, Ahmad A, Khan AU..  (2010)  Synthesis, antibacterial and antifungal activities of 6,5 fused steroidal oxazoles in cholestane series.,  45  (3): [PMID:20031281] [10.1016/j.ejmech.2009.12.004]
    84. Schmidt LE, Deyrup ST, Baltrusaitis J, Swenson DC, Wicklow DT, Gloer JB..  (2010)  Hymenopsins A and B and a macrophorin analogue from a fungicolous Hymenopsis sp.,  73  (3): [PMID:19928955] [10.1021/np900613d]
    85. Nono EC, Mkounga P, Kuete V, Marat K, Hultin PG, Nkengfack AE..  (2010)  Pycnanthulignenes A-D, antimicrobial cyclolignene derivatives from the roots of Pycnanthus angolensis.,  73  (2): [PMID:20055477] [10.1021/np9007393]
    86. Costa EV, Marques FA, Pinheiro ML, Vaz NP, Duarte MC, Delarmelina C, Braga RM, Maia BH..  (2009)  7,7-Dimethylaporphine alkaloids from the stem of Guatteriopsis friesiana.,  72  (8): [PMID:19639965] [10.1021/np800788n]
    87. Dawane BS, Konda SG, Mandawad GG, Shaikh BM..  (2010)  Poly(ethylene glycol) (PEG-400) as an alternative reaction solvent for the synthesis of some new 1-(4-(4'-chlorophenyl)-2-thiazolyl)-3-aryl-5-(2-butyl-4-chloro-1H-imidazol-5yl)-2-pyrazolines and their in vitro antimicrobial evaluation.,  45  (1): [PMID:19896247] [10.1016/j.ejmech.2009.10.015]
    88. Saeed S, Rashid N, Jones PG, Ali M, Hussain R..  (2010)  Synthesis, characterization and biological evaluation of some thiourea derivatives bearing benzothiazole moiety as potential antimicrobial and anticancer agents.,  45  (4): [PMID:20056520] [10.1016/j.ejmech.2009.12.016]
    89. Khobragade CN, Bodade RG, Konda SG, Dawane BS, Manwar AV..  (2010)  Synthesis and antimicrobial activity of novel pyrazolo[3,4-d]pyrimidin derivatives.,  45  (4): [PMID:20096486] [10.1016/j.ejmech.2009.12.040]
    90. Tandon VK, Maurya HK, Verma MK, Kumar R, Shukla PK..  (2010)  'On water' assisted synthesis and biological evaluation of nitrogen and sulfur containing hetero-1,4-naphthoquinones as potent antifungal and antibacterial agents.,  45  (6): [PMID:20207052] [10.1016/j.ejmech.2010.02.023]
    91. Nandakumar A, Thirumurugan P, Perumal PT, Vembu P, Ponnuswamy MN, Ramesh P..  (2010)  One-pot multicomponent synthesis and anti-microbial evaluation of 2'-(indol-3-yl)-2-oxospiro(indoline-3,4'-pyran) derivatives.,  20  (14): [PMID:20621732] [10.1016/j.bmcl.2010.05.025]
    92. Aly MM, Mohamed YA, El-Bayouki KA, El-Bayouki KA, Basyouni WM, Basyouni WM, Abbas SY..  (2010)  Synthesis of some new 4(3H)-quinazolinone-2-carboxaldehyde thiosemicarbazones and their metal complexes and a study on their anticonvulsant, analgesic, cytotoxic and antimicrobial activities - part-1.,  45  (8): [PMID:20510483] [10.1016/j.ejmech.2010.04.020]
    93. Ma WS, Mutka T, Vesley B, Amsler MO, McClintock JB, Amsler CD, Perman JA, Singh MP, Maiese WM, Zaworotko MJ, Kyle DE, Baker BJ..  (2009)  Norselic acids A-E, highly oxidized anti-infective steroids that deter mesograzer predation, from the Antarctic sponge Crella sp.,  72  (10): [PMID:19848433] [10.1021/np900382x]
    94. Radulović N, Denić M, Stojanović-Radić Z..  (2010)  Antimicrobial phenolic abietane diterpene from Lycopus europaeus L. (Lamiaceae).,  20  (17): [PMID:20674349] [10.1016/j.bmcl.2010.07.063]
    95. Gadakh AV, Pandit C, Rindhe SS, Karale BK..  (2010)  Synthesis and antimicrobial activity of novel fluorine containing 4-(substituted-2-hydroxybenzoyl)-1H-pyrazoles and pyrazolyl benzo[d]oxazoles.,  20  (18): [PMID:20724151] [10.1016/j.bmcl.2010.07.019]
    96. Liesen AP, de Aquino TM, Carvalho CS, Lima VT, de Araújo JM, de Lima JG, de Faria AR, de Melo EJ, Alves AJ, Alves EW, Alves AQ, Góes AJ..  (2010)  Synthesis and evaluation of anti-Toxoplasma gondii and antimicrobial activities of thiosemicarbazides, 4-thiazolidinones and 1,3,4-thiadiazoles.,  45  (9): [PMID:20541294] [10.1016/j.ejmech.2010.05.017]
    97. Kamal A, Shetti RV, Azeeza S, Ahmed SK, Swapna P, Reddy AM, Khan IA, Sharma S, Abdullah ST..  (2010)  Anti-tubercular agents. Part 5: synthesis and biological evaluation of benzothiadiazine 1,1-dioxide based congeners.,  45  (10): [PMID:20705368] [10.1016/j.ejmech.2010.07.015]
    98. Fritsche TR, Rhomberg PR, Sader HS, Jones RN..  (2008)  Antimicrobial activity of omiganan pentahydrochloride against contemporary fungal pathogens responsible for catheter-associated infections.,  52  (3): [PMID:18180345] [10.1128/aac.01475-07]
    99. Patel MM, Mali MD, Patel SK..  (2010)  Bernthsen synthesis, antimicrobial activities and cytotoxicity of acridine derivatives.,  20  (21): [PMID:20850303] [10.1016/j.bmcl.2010.06.001]
    100. Kamdar NR, Haveliwala DD, Mistry PT, Patel SK..  (2010)  Design, synthesis and in vitro evaluation of antitubercular and antimicrobial activity of some novel pyranopyrimidines.,  45  (11): [PMID:20805011] [10.1016/j.ejmech.2010.08.014]
    101. Hilmy KM, Khalifa MM, Hawata MA, Keshk RM, el-Torgman AA..  (2010)  Synthesis of new pyrrolo[2,3-d]pyrimidine derivatives as antibacterial and antifungal agents.,  45  (11): [PMID:20828885] [10.1016/j.ejmech.2010.08.043]
    102. Vandeputte P, Tronchin G, Larcher G, Ernoult E, Bergès T, Chabasse D, Bouchara JP..  (2008)  A nonsense mutation in the ERG6 gene leads to reduced susceptibility to polyenes in a clinical isolate of Candida glabrata.,  52  (10): [PMID:18694952] [10.1128/aac.00423-08]
    103. Shelke S, Mhaske G, Gadakh S, Gill C..  (2010)  Green synthesis and biological evaluation of some novel azoles as antimicrobial agents.,  20  (24): [PMID:21074427] [10.1016/j.bmcl.2010.10.111]
    104. Abbas HA, Hafez HN, El-Gazzar AR..  (2011)  Synthesis, in vitro antimicrobial and in vivo antitumor evaluation of novel pyrimidoquinolines and its nucleoside derivatives.,  46  (1): [PMID:21074295] [10.1016/j.ejmech.2010.09.071]
    105. Lamping E, Ranchod A, Nakamura K, Tyndall JD, Niimi K, Holmes AR, Niimi M, Cannon RD..  (2009)  Abc1p is a multidrug efflux transporter that tips the balance in favor of innate azole resistance in Candida krusei.,  53  (2): [PMID:19015352] [10.1128/aac.01095-08]
    106. Sabry NM, Mohamed HM, Khattab ES, Motlaq SS, El-Agrody AM..  (2011)  Synthesis of 4H-chromene, coumarin, 12H-chromeno[2,3-d]pyrimidine derivatives and some of their antimicrobial and cytotoxicity activities.,  46  (2): [PMID:21216502] [10.1016/j.ejmech.2010.12.015]
    107. Zitko J, Dolezal M, Dolezal M, Svobodova M, Vejsova M, Kunes J, Kucera R, Jilek P..  (2011)  Synthesis and antimycobacterial properties of N-substituted 6-amino-5-cyanopyrazine-2-carboxamides.,  19  (4): [PMID:21273083] [10.1016/j.bmc.2010.12.054]
    108. Seneviratne CJ, Jin LJ, Samaranayake YH, Samaranayake LP..  (2008)  Cell density and cell aging as factors modulating antifungal resistance of Candida albicans biofilms.,  52  (9): [PMID:18625775] [10.1128/aac.00541-08]
    109. Gao SS, Li XM, Zhang Y, Li CS, Cui CM, Wang BG..  (2011)  Comazaphilones A-F, azaphilone derivatives from the marine sediment-derived fungus Penicillium commune QSD-17.,  74  (2): [PMID:21226488] [10.1021/np100788h]
    110. Matthews EJ, Kruhlak NL, Weaver JL, Benz RD, Contrera JF..  (2004)  Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.,  (4): [PMID:16472241] [10.2174/1570163043334794]
    111. Unpublished dataset, 
    112. Siddiqui IN, Zahoor A, Hussain H, Ahmed I, Ahmad VU, Padula D, Draeger S, Schulz B, Meier K, Steinert M, Kurtán T, Flörke U, Pescitelli G, Krohn K..  (2011)  Diversonol and blennolide derivatives from the endophytic fungus Microdiplodia sp.: absolute configuration of diversonol.,  74  (3): [PMID:21244021] [10.1021/np100730b]
    113. Shim SH, Baltrusaitis J, Gloer JB, Wicklow DT..  (2011)  Phomalevones A-C: dimeric and pseudodimeric polyketides from a fungicolous Hawaiian isolate of Phoma sp. (Cucurbitariaceae).,  74  (3): [PMID:21247198] [10.1021/np100791b]
    114. Türkmen H, Ceyhan N, Ulkü Karabay Yavaşoğlu N, Ozdemir G, Cetinkaya B..  (2011)  Synthesis and antimicrobial activities of hexahydroimidazo[1,5-a]pyridinium bromides with varying benzyl substituents.,  46  (7): [PMID:21543140] [10.1016/j.ejmech.2011.04.012]
    115. Mungra DC, Patel MP, Rajani DP, Patel RG..  (2011)  Synthesis and identification of β-aryloxyquinolines and their pyrano[3,2-c]chromene derivatives as a new class of antimicrobial and antituberculosis agents.,  46  (9): [PMID:21741732] [10.1016/j.ejmech.2011.06.022]
    116. Akhaja TN, Raval JP..  (2011)  1,3-Dihydro-2H-indol-2-ones derivatives: design, synthesis, in vitro antibacterial, antifungal and antitubercular study.,  46  (11): [PMID:21981980] [10.1016/j.ejmech.2011.09.023]
    117. Makawana JA, Mungra DC, Patel MP, Patel RG..  (2011)  Microwave assisted synthesis and antimicrobial evaluation of new fused pyran derivatives bearing 2-morpholinoquinoline nucleus.,  21  (20): [PMID:21890359] [10.1016/j.bmcl.2011.07.123]
    118. Scott S. Auerbach, DrugMatrix¨ and ToxFX¨ Coordinator National Toxicology Program. DrugMatrix in vitro pharmacology data, 
    119. Chen M, Vijay V, Shi Q, Liu Z, Fang H, Tong W..  (2011)  FDA-approved drug labeling for the study of drug-induced liver injury.,  16  (15-16): [PMID:21624500] [10.1016/j.drudis.2011.05.007]
    120. Liu Z, Shi Q, Ding D, Kelly R, Fang H, Tong W..  (2011)  Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).,  (12): [PMID:22194678] [10.1371/journal.pcbi.1002310]
    121. Tandon VK, Maurya HK, Mishra NN, Shukla PK..  (2011)  Micelles catalyzed chemoselective synthesis 'in water' and biological evaluation of oxygen containing hetero-1,4-naphthoquinones as potential antifungal agents.,  21  (21): [PMID:21930375] [10.1016/j.bmcl.2011.08.095]
    122. Ibis C, Tuyun AF, Ozsoy-Gunes Z, Bahar H, Stasevych MV, Musyanovych RY, Komarovska-Porokhnyavets O, Novikov V..  (2011)  Synthesis and biological evaluation of novel nitrogen- and sulfur-containing hetero-1,4-naphthoquinones as potent antifungal and antibacterial agents.,  46  (12): [PMID:22019185] [10.1016/j.ejmech.2011.09.048]
    123. Berest GG, Voskoboynik OY, Kovalenko SI, Antypenko OM, Nosulenko IS, Katsev AM, Shandrovskaya OS..  (2011)  Synthesis and biological activity of novel N-cycloalkyl-(cycloalkylaryl)-2-[(3-R-2-oxo-2H-[1,2,4]triazino[2,3-c]quinazoline-6-yl)thio]acetamides.,  46  (12): [PMID:22051065] [10.1016/j.ejmech.2011.10.022]
    124. Janiszewska J, Sowińska M, Rajnisz A, Solecka J, Łącka I, Milewski S, Urbańczyk-Lipkowska Z..  (2012)  Novel dendrimeric lipopeptides with antifungal activity.,  22  (3): [PMID:22230049] [10.1016/j.bmcl.2011.12.051]
    125. Rajanarendar E, Nagi Reddy M, Rama Krishna S, Govardhan Reddy K, Reddy YN, Rajam MV..  (2012)  Design, synthesis, in vitro antimicrobial and anticancer activity of novel methylenebis-isoxazolo[4,5-b]azepines derivatives.,  50  [PMID:22385674] [10.1016/j.ejmech.2012.02.013]
    126. Sun HF, Li XM, Meng L, Cui CM, Gao SS, Li CS, Huang CG, Wang BG..  (2012)  Asperolides A-C, tetranorlabdane diterpenoids from the marine alga-derived endophytic fungus Aspergillus wentii EN-48.,  75  (2): [PMID:22283451] [10.1021/np2006742]
    127. Gaikwad ND, Patil SV, Bobade VD..  (2012)  Synthesis and biological evaluation of some novel thiazole substituted benzotriazole derivatives.,  22  (10): [PMID:22520260] [10.1016/j.bmcl.2012.03.094]
    128. Parmar NJ, Pansuriya BR, Barad HA, Kant R, Gupta VK..  (2012)  An improved microwave assisted one-pot synthesis, and biological investigations of some novel aryldiazenyl chromeno fused pyrrolidines.,  22  (12): [PMID:22607678] [10.1016/j.bmcl.2012.04.070]
    129. Parmar NJ, Barad HA, Pansuriya BR, Teraiya SB, Gupta VK, Kant R..  (2012)  An efficient one-pot synthesis, structure, antimicrobial and antioxidant investigations of some novel quinolyldibenzo[b,e][1,4]diazepinones.,  22  (11): [PMID:22560587] [10.1016/j.bmcl.2012.03.100]
    130. Gaikwad ND, Patil SV, Bobade VD..  (2012)  Hybrids of ravuconazole: synthesis and biological evaluation.,  54  [PMID:22652223] [10.1016/j.ejmech.2012.05.010]
    131. Shah NM, Patel MP, Patel RG..  (2012)  New N-arylamino biquinoline derivatives: synthesis, antimicrobial, antituberculosis, and antimalarial evaluation.,  54  [PMID:22652224] [10.1016/j.ejmech.2012.05.004]
    132. Okanya PW, Mohr KI, Gerth K, Steinmetz H, Huch V, Jansen R, Müller R..  (2012)  Hyaladione, an S-methyl cyclohexadiene-dione from Hyalangium minutum.,  75  (4): [PMID:22497473] [10.1021/np200776v]
    133. Reddy TV, Prabhavathi Devi BL, Prasad RB, Poornima M, Ganesh Kumar C..  (2012)  Total synthesis and antifungal activity of (2S,3R)-2-aminododecan-3-ol.,  22  (14): [PMID:22704888] [10.1016/j.bmcl.2012.05.082]
    134. Lima-Junior CG, Vasconcellos ML..  (2012)  Morita-Baylis-Hillman adducts: biological activities and potentialities to the discovery of new cheaper drugs.,  20  (13): [PMID:22632793] [10.1016/j.bmc.2012.04.061]
    135. Gavade SN, Markad VL, Kodam KM, Shingare MS, Mane DV..  (2012)  Synthesis and biological evaluation of novel 2,4,6-triazine derivatives as antimicrobial agents.,  22  (15): [PMID:22742908] [10.1016/j.bmcl.2012.05.111]
    136. Shelke SN, Mhaske GR, Bonifácio VD, Gawande MB..  (2012)  Green synthesis and anti-infective activities of fluorinated pyrazoline derivatives.,  22  (17): [PMID:22832312] [10.1016/j.bmcl.2012.06.072]
    137. Şardan M, Sezer S, Günel A, Akkaya M, Tanyeli C..  (2012)  Synthesis and biological evaluation of optically active conjugated γ- and δ-lactone derivatives.,  22  (18): [PMID:22902655] [10.1016/j.bmcl.2012.07.090]
    138. USP Dictionary of USAN and International Names (2010 edition) and USAN registrations 2007-date, 
    139. Karlgren M, Vildhede A, Norinder U, Wisniewski JR, Kimoto E, Lai Y, Haglund U, Artursson P..  (2012)  Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.,  55  (10): [PMID:22541068] [10.1021/jm300212s]
    140. Kathiravan MK, Salake AB, Chothe AS, Dudhe PB, Watode RP, Mukta MS, Gadhwe S..  (2012)  The biology and chemistry of antifungal agents: a review.,  20  (19): [PMID:22902032] [10.1016/j.bmc.2012.04.045]
    141. Li S, Breaker RR..  (2012)  Fluoride enhances the activity of fungicides that destabilize cell membranes.,  22  (9): [PMID:22460034] [10.1016/j.bmcl.2012.03.006]
    142. Addla D, Bhima, Sridhar B, Devi A, Kantevari S..  (2012)  Design, synthesis and antimicrobial evaluation of novel 1-benzyl 2-butyl-4-chloroimidazole embodied 4-azafluorenones via molecular hybridization approach.,  22  (24): [PMID:23147074] [10.1016/j.bmcl.2012.10.042]
    143. Chhabria M, Rathod I, Vala K, Patel P.  (2011)  Identification of important structural features of thiazolo[4,5-d]pyrimidines required for potent antifungal activity,  20  (9): [10.1007/s00044-010-9378-2]
    144. Kaya M, Basar E, Colak F.  (2011)  Synthesis and antimicrobial activity of some bisoctahydroxanthene-1,8-dione derivatives,  20  (8): [10.1007/s00044-010-9459-2]
    145. Mohammed Musthafa TN, Siddiqui ZN, Husain FM, Ahmad I.  (2011)  Microwave-assisted solvent-free synthesis of biologically active novel heterocycles from 3-formylchromones,  20  (9): [10.1007/s00044-010-9386-2]
    146. Mungra DC, Patel MP, Patel RG.  (2011)  Microwave-assisted synthesis of some new tetrazolo[1,5-a]quinoline-based benzimidazoles catalyzed by p-TsOH and investigation of their antimicrobial activity,  20  (6): [10.1007/s00044-010-9388-0]
    147. Malhotra M, Sharma S, Deep A.  (2012)  Synthesis, characterization and antimicrobial evaluation of novel derivatives of isoniazid,  21  (7): [10.1007/s00044-011-9634-0]
    148. Kathrotiya HG, Patel MP.  (2012)  Microwave-assisted synthesis of 3-indolyl substituted 4H-chromenes catalyzed by DMAP and their antimicrobial activity,  21  (11): [10.1007/s00044-011-9861-4]
    149. Patel NB, Pathak KK.  (2012)  Pyridoquinolones containing azetidinones: synthesis and their biological evaluation,  21  (8): [10.1007/s00044-011-9728-8]
    150. Edayadulla N, Ramesh P.  (2012)  Synthesis and physiological evaluation of new N-nitroso-2,6-dicarbethoxy-3,5-diaryltetrahydro-1,4-thiazine-1,1-dioxides,  21  (8): [10.1007/s00044-011-9729-7]
    151. Myangar KN, Raval JP.  (2012)  Design, synthesis, and in vitro antimicrobial activities of novel azetidinyl-3-quinazolin-4-one hybrids,  21  (10): [10.1007/s00044-011-9808-9]
    152. Siddiqui ZN, Musthafa TNM, Praveen S, Farooq F.  (2011)  Zn(Proline)2-catalyzed Knoevenagel condensation under solvent-free/aqueous conditions and biological evaluation of products,  20  (9): [10.1007/s00044-010-9376-4]
    153. Thumar NJ, Patel MP.  (2012)  Synthesis, characterization and biological activity of some new carbostyril bearing 1H-pyrazole moiety,  21  (8): [10.1007/s00044-011-9693-2]
    154. Altundas A, Sar N, Colak N, Ogutcu H.  (2010)  Synthesis and biological activity of new cycloalkylthiophene-Schiff bases and their Cr(III) and Zn(II) complexes,  19  (6): [10.1007/s00044-009-9214-8]
    155. Patel NB, Patel SD.  (2010)  Synthesis and antimicrobial study of fluoroquinolone-based 4-thiazolidinones,  19  (8): [10.1007/s00044-009-9228-2]
    156. Shah PM, Patel MP.  (2012)  Zn(OTf)2-catalyzed three component, one-pot cyclocondensation reaction of some new octahydroquinazolinone derivatives and access their bio-potential,  21  (7): [10.1007/s00044-011-9628-y]
    157. Rizk O, Mahran M, El-Khawass S, Shams El-Dine S, Ibrahim EA.  (2005)  Synthesis of Some New Antimicrobial Thiadiazolyl and Oxadiazolyl Quinoline Derivatives,  14  (5): [10.1007/s00044-005-0138-7]
    158. Gaonkar S, Rai KL, Prabhuswamy B.  (2006)  Synthesis of novel 3-[5-ethyl-2-(2-phenoxy-ethyl)-pyridin]-5-substituted isoxazoline libraries via 1,3-dipolar cycloaddition and evaluation of antimicrobial activities,  15  (7): [10.1007/s00044-006-0015-z]
    159. Patel JR, Dholakiya BZ.  (2012)  Synthesis of 1-(4-((E)-3-arylacryloyl) phenyl)-3,4-dibromo-1H-pyrrole-2,5-diones and screening for anti-Candida and antituberculosis activity,  21  (8): [10.1007/s00044-011-9718-x]
    160. Kamdar NR, Haveliwala DD, Mistry PT, Patel SK.  (2011)  Synthesis and evaluation of in vitro antitubercular activity and antimicrobial activity of some novel 4H-chromeno[2,3-d]pyrimidine via 2-amino-4-phenyl-4H-chromene-3-carbonitriles,  20  (7): [10.1007/s00044-010-9399-x]
    161. El-Sabbagh OI, El-Sadek ME, Lashine SM, Yassin SH, El-Nabtity SM.  (2009)  Synthesis of new 2(1H)-quinoxalinone derivatives for antimicrobial and antiinflammatory evaluation,  18  (9): [10.1007/s00044-009-9203-y]
    162. Sar N, Piskin N, Ogutcu H, Kurnaz N.  (2013)  Spectroscopic characterization of novel d-amino acid-Schiff bases and their Cr(III) and Ni(II) complexes as antimicrobial agents,  22  (2): [10.1007/s00044-012-0039-5]
    163. Asundaria ST, Pannecouque C, De Clercq E, Supuran CT, Patel KC.  (2013)  Synthesis of novel biologically active methylene derivatives of sydnones,  22  (12): [10.1007/s00044-013-0567-7]
    164. Aswathanarayanappa C, Bheemappa E, Bodke YD, Bhovi VK, Ningegowda R, Shivakumar MC, Peethambar SK, Telkar S.  (2013)  5-phenyl-1-benzofuran-2-yl derivatives: synthesis, antimicrobial, and antioxidant activity,  22  (1): [10.1007/s00044-012-0017-y]
    165. Jardosh HH, Patel MP.  (2013)  Microwave-assisted CAN-catalyzed solvent-free synthesis of N-allyl quinolone-based pyrano[4,3-b]chromene and benzopyrano[3,2-c]chromene derivatives and their antimicrobial activity,  22  (2): [10.1007/s00044-012-0085-z]
    166. Shah NM, Patel MP, Patel RG.  (2013)  New N-arylamino biquinoline derivatives: microwave-assisted synthesis and their antimicrobial activities,  22  (1): [10.1007/s00044-012-0031-0]
    167. Aslan HG, Karacan N.  (2013)  Aromatic sulfonyl hydrazides and sulfonyl hydrazones: antimicrobial activity and physical properties,  22  (3): [10.1007/s00044-012-0104-0]
    168. Hussain H, Ahmed I, Schulz B, Draeger S, Krohn K..  (2012)  Pyrenocines J-M: four new pyrenocines from the endophytic fungus, Phomopsis sp.,  83  (3): [PMID:22233864] [10.1016/j.fitote.2011.12.017]
    169. Fogliani B, Raharivelomanana P, Bianchini JP, Bouraïma-Madjèbi S, Hnawia E..  (2005)  Bioactive ellagitannins from Cunonia macrophylla, an endemic Cunoniaceae from New Caledonia.,  66  (2): [PMID:15652581] [10.1016/j.phytochem.2004.11.016]
    170. Tian SZ, Pu X, Luo G, Zhao LX, Xu LH, Li WJ, Luo Y..  (2013)  Isolation and characterization of new p-Terphenyls with antifungal, antibacterial, and antioxidant activities from halophilic actinomycete Nocardiopsis gilva YIM 90087.,  61  (12): [PMID:23441911] [10.1021/jf400718w]
    171. Patel AA, Lad HB, Pandya KR, Patel CV, Brahmbhatt DI.  (2013)  Synthesis of a new series of 2-(2-oxo-2H-chromen-3-yl)-5H-chromeno[4,3-b]pyridin-5-ones by two facile methods and evaluation of their antimicrobial activity,  22  (10): [10.1007/s00044-013-0489-4]
    172. Savaliya PP, Akbari VK, Modi JA, Patel KC.  (2013)  Synthesis, characterization, and antimicrobial screening of some Mannich base sydnone derivatives,  22  (12): [10.1007/s00044-013-0568-6]
    173. Dholariya HR, Patel KS, Patel JC, Patel AK, Patel KD.  (2013)  Thermal, kinetic, spectroscopic studies and anti-microbial, anti-tuberculosis, anti-oxidant properties of clioquinol and benzo-coumarin derivatives mixed complexes with copper ion,  22  (12): [10.1007/s00044-013-0576-6]
    174. Kanani MB, Patel MP.  (2013)  Synthesis and in vitro antimicrobial evaluation of novel 2-amino-6-(phenylthio)-4-(2-(phenylthio)quinolin-3-yl)pyridine-3,5-dicarbonitriles,  22  (6): [10.1007/s00044-012-0292-7]
    175. Ibis C, Tuyun AF, Bahar H, Ayla SS, Stasevych MV, Musyanovych RY, Komarovska-Porokhnyavets O, Novikov V.  (2013)  Synthesis of novel 1,4-naphthoquinone derivatives: antibacterial and antifungal agents,  22  (6): [10.1007/s00044-012-0300-y]
    176. Bhila VG, Patel CV, Patel NH, Brahmbhatt DI.  (2013)  One pot synthesis of some novel coumarins containing 5-(substituted-2-hydroxybenzoyl) pyridine as a new class of antimicrobial and antituberculosis agents,  22  (9): [10.1007/s00044-012-0437-8]
    177. Murthy YLN, Durga G, Jha A.  (2013)  Synthesis, characterization, and antimicrobial activity of some new 2-diazo-benzimidazole derivatives and their Ni(II), Cu(II), and Ag(I) complexes,  22  (5): [10.1007/s00044-012-0220-x]
    178. Jardosh HH, Patel MP.  (2013)  Microwave-induced CAN promoted atom-economic synthesis of 1H-benzo[b]xanthene and 4H-benzo[g]chromene derivatives of N-allyl quinolone and their antimicrobial activity,  22  (6): [10.1007/s00044-012-0301-x]
    179. Sangani CB, Shah NM, Patel MP, Patel RG.  (2013)  Microwave-assisted synthesis of novel 4H-chromene derivatives bearing 2-aryloxyquinoline and their antimicrobial activity assessment,  22  (8): [10.1007/s00044-012-0381-7]
    180. Yadlapalli RK, Chourasia OP, Jogi MP, Podile AR, Perali RS.  (2013)  Design, synthesis and in vitro antimicrobial activity of novel phenylbenzamido-aminothiazole-based azasterol mimics,  22  (6): [10.1007/s00044-012-0314-5]
    181. Akhaja TN, Raval JP.  (2013)  New carbodithioate derivatives: synthesis, characterization, and in vitro antibacterial, antifungal, antitubercular, and antimalarial activity,  22  (10): [10.1007/s00044-013-0472-0]
    182. Sharma UK, Sood S, Sharma N, Rahi P, Kumar R, Sinha AK, Gulati A.  (2013)  Synthesis and SAR investigation of natural phenylpropene-derived methoxylated cinnamaldehydes and their novel Schiff bases as potent antimicrobial and antioxidant agents,  22  (11): [10.1007/s00044-013-0484-9]
    183. Konduru NK, Dey S, Sajid M, Owais M, Ahmed N..  (2013)  Synthesis and antibacterial and antifungal evaluation of some chalcone based sulfones and bisulfones.,  59  [PMID:23202847] [10.1016/j.ejmech.2012.09.004]
    184. Liu HX, Chen K, Sun QY, Yang FM, Hu GW, Wang YH, Long CL..  (2013)  Nudibaccatumone, a trimer comprising a phenylpropanoid and two sesquiterpene moieties from Piper nudibaccatum.,  76  (4): [PMID:23544451] [10.1021/np300703u]
    185. Parmar NJ, Patel RA, Parmar BD, Talpada NP..  (2013)  An efficient domino reaction in ionic liquid: synthesis and biological evaluation of some pyrano- and thiopyrano-fused heterocycles.,  23  (6): [PMID:23414843] [10.1016/j.bmcl.2013.01.079]
    186. Kathrotiya HG, Patel MP..  (2013)  Synthesis and identification of β-aryloxyquinoline based diversely fluorine substituted N-aryl quinolone derivatives as a new class of antimicrobial, antituberculosis and antioxidant agents.,  63  [PMID:23567957] [10.1016/j.ejmech.2013.03.017]
    187. Kanawade SB, Toche RB, Rajani DP..  (2013)  Synthetic tactics of new class of 4-aminothieno[2,3-d]pyrimidine-6-carbonitrile derivatives acting as antimicrobial agents.,  64  [PMID:23644214] [10.1016/j.ejmech.2013.03.039]
    188. Jardosh HH, Patel MP..  (2013)  Design and synthesis of biquinolone-isoniazid hybrids as a new class of antitubercular and antimicrobial agents.,  65  [PMID:23747804] [10.1016/j.ejmech.2013.05.003]
    189. Tucaliuc RA, Cotea VV, Niculaua M, Tuchilus C, Mantu D, Mangalagiu II..  (2013)  New pyridazine-fluorine derivatives: synthesis, chemistry and biological activity. Part II.,  67  [PMID:23891981] [10.1016/j.ejmech.2013.04.069]
    190. Ibis C, Tuyun AF, Bahar H, Ayla SS, Stasevych MV, Musyanovych RY, Komarovska-Porokhnyavets O, Novikov V.  (2013)  Nucleophilic substitution reactions of 1,4-naphthoquinone and biologic properties of novel S-, S,S-, N-, and N,S-substituted 1,4-naphthoquinone derivatives,  [10.1007/s00044-013-0806-y]
    191. Khan FG, Yadav MV, Sagar AD.  (2013)  Synthesis, characterization, and antimicrobial evaluation of novel trichalcones containing core s-triazine moiety,  [10.1007/s00044-013-0837-4]
    192. Godhani DR, Dobariya PB, Jogel AA, Sanghani AM, Mehta JP.  (2013)  An efficient synthesis, characterization, and antimicrobial screening of tetrahydropyrimidine derivatives,  [10.1007/s00044-013-0840-9]
    193. Kuchkova K, Aricu A, Secara E, Barba A, Vlad P, Ungur N, Tuchilus C, Shova S, Zbancioc G, Mangalagiu II.  (2013)  Design, synthesis, and antimicrobial activity of some novel homodrimane sesquiterpenoids with diazine skeleton,  [10.1007/s00044-013-0720-3]
    194. Thirupathi G, Venkatanarayana M, Dubey PK, Bharathi Kumari Y.  (2013)  Eco-friendly synthesis and antimicrobial activities of substituted-5-(1H-indol-3-yl)methylene)-2,2-dimethyl-1,3-dioxane-4,6-dione derivatives,  [10.1007/s00044-013-0728-8]
    195. El-Gazzar MG, Zaher NH, El-Tablawy SY.  (2013)  Morphological changes of some pathogenic microbial strains induced by novel thiadiazole derivatives,  [10.1007/s00044-013-0779-x]
    196. De Bruyn T, van Westen GJ, Ijzerman AP, Stieger B, de Witte P, Augustijns PF, Annaert PP..  (2013)  Structure-based identification of OATP1B1/3 inhibitors.,  83  (6): [PMID:23571415] [10.1124/mol.112.084152]
    197. Thongbai B, Surup F, Mohr K, Kuhnert E, Hyde KD, Stadler M..  (2013)  Gymnopalynes A and B, chloropropynyl-isocoumarin antibiotics from cultures of the basidiomycete Gymnopus sp.,  76  (11): [PMID:24175638] [10.1021/np400609f]
    198. Ningaiah S, Bhadraiah UK, Doddaramappa SD, Keshavamurthy S, Javarasetty C..  (2014)  Novel pyrazole integrated 1,3,4-oxadiazoles: synthesis, characterization and antimicrobial evaluation.,  24  (1): [PMID:24316123] [10.1016/j.bmcl.2013.11.029]
    199. McMullin DR, Nsiama TK, Miller JD..  (2014)  Isochromans and α-pyrones from Penicillium corylophilum.,  77  (2): [PMID:24456578] [10.1021/np4005486]
    200. Biour M, Ben Salem C, Chazouillères O, Grangé JD, Serfaty L, Poupon R..  (2004)  [Drug-induced liver injury; fourteenth updated edition of the bibliographic database of liver injuries and related drugs].,  28  (8-9): [PMID:15646539] [10.1016/s0399-8320(04)95062-2]
    201. Mert S, Kasımoğulları R, İça T, Çolak F, Altun A, Ok S..  (2014)  Synthesis, structure-activity relationships, and in vitro antibacterial and antifungal activity evaluations of novel pyrazole carboxylic and dicarboxylic acid derivatives.,  78  [PMID:24681068] [10.1016/j.ejmech.2014.03.033]
    202. Kalaria PN, Satasia SP, Raval DK..  (2014)  Synthesis, characterization and pharmacological screening of some novel 5-imidazopyrazole incorporated polyhydroquinoline derivatives.,  78  [PMID:24681985] [10.1016/j.ejmech.2014.02.015]
    203. Jansen R, Mohr KI, Bernecker S, Stadler M, Müller R..  (2014)  Indothiazinone, an indolyl thiazolyl ketone from a novel myxobacterium belonging to the Sorangiineae.,  77  (4): [PMID:24697522] [10.1021/np500144t]
    204. Jing SX, Luo SH, Li CH, Hua J, Wang YL, Niu XM, Li XN, Liu Y, Huang CS, Wang Y, Li SH..  (2014)  Biologically active dichapetalins from Dichapetalum gelonioides.,  77  (4): [PMID:24597894] [10.1021/np400971r]
    205. Mitra S, Mukherjee S, Sen SK, Hajra A..  (2014)  Environmentally benign synthesis and antimicrobial study of novel chalcogenophosphates.,  24  (9): [PMID:24685541] [10.1016/j.bmcl.2014.03.008]
    206. Walker KA, Braemer AC, Hitt S, Jones RE, Matthews TR..  (1978)  1-[4-(4-Chlorophenyl)-2-(2,6-dichlorophenylthio)-n-butyl]-1H-imidazole nitrate, a new potent antifungal agent.,  21  (8): [PMID:357722] [10.1021/jm00206a028]
    207. Ferreira EA, Reigada JB, Correia MV, Young MC, Guimarães EF, Franchi GC, Nowill AE, Lago JH, Yamaguchi LF, Kato MJ..  (2014)  Antifungal and cytotoxic 2-acylcyclohexane-1,3-diones from Peperomia alata and P. trineura.,  77  (6): [PMID:24905499] [10.1021/np500130x]
    208. Emirdağ-Öztürk S, Karayıldırım T, Çapcı-Karagöz A, Alankuş-Çalışkan Ö, Özmen A, Poyrazoğlu-Çoban E..  (2014)  Synthesis, antimicrobial and cytotoxic activities, and structure-activity relationships of gypsogenin derivatives against human cancer cells.,  82  [PMID:24941130] [10.1016/j.ejmech.2014.05.084]
    209. Jansen R, Sood S, Mohr KI, Kunze B, Irschik H, Stadler M, Müller R..  (2014)  Nannozinones and sorazinones, unprecedented pyrazinones from myxobacteria.,  77  (11): [PMID:25397992] [10.1021/np500632c]
    210. Mazimba O, Wale K, Loeto D, Kwape T..  (2014)  Antioxidant and antimicrobial studies on fused-ring pyrazolones and isoxazolones.,  22  (23): [PMID:25456077] [10.1016/j.bmc.2014.10.015]
    211. Karad SC, Purohit VB, Raval DK..  (2014)  Design, synthesis and characterization of fluoro substituted novel pyrazolylpyrazolines scaffold and their pharmacological screening.,  84  [PMID:25016227] [10.1016/j.ejmech.2014.07.008]
    212. Kukowska M, Kukowska-Kaszuba M, Dzierzbicka K..  (2015)  In vitro studies of antimicrobial activity of Gly-His-Lys conjugates as potential and promising candidates for therapeutics in skin and tissue infections.,  25  (3): [PMID:25556094] [10.1016/j.bmcl.2014.12.029]
    213. Seebacher W, Wolkinger V, Faist J, Kaiser M, Brun R, Saf R, Bucar F, Gröblacher B, Brantner A, Merino V, Kalia Y, Scapozza L, Perozzo R, Weis R..  (2015)  Synthesis of 3-azabicyclo[3.2.2]nonanes and their antiprotozoal activities.,  25  (7): [PMID:25746816] [10.1016/j.bmcl.2015.02.044]
    214. Zhang LJ, Zhang JA, Zou XZ, Liu YJ, Li N, Zhang ZJ, Li Y..  (2015)  Studies on antimicrobial effects of four ligands and their transition metal complexes with 8-mercaptoquinoline and pyridine terminal groups.,  25  (8): [PMID:25791454] [10.1016/j.bmcl.2015.02.056]
    215. Drug metabolism data, 
    216. Surup F, Thongbai B, Kuhnert E, Sudarman E, Hyde KD, Stadler M..  (2015)  Deconins A-E: Cuparenic and Mevalonic or Propionic Acid Conjugates from the Basidiomycete Deconica sp. 471.,  78  (4): [PMID:25871540] [10.1021/np5010104]
    217. Doddaramappa SD, Lokanatha Rai KM, Srikantamurthy N, Chandra, Chethan J..  (2015)  Novel 5-functionalized-pyrazoles: Synthesis, characterization and pharmacological screening.,  25  (17): [PMID:26152425] [10.1016/j.bmcl.2015.06.050]
    218. Vilipić J, Novaković I, Stanojković T, Matić I, Šegan D, Kljajić Z, Sladić D..  (2015)  Synthesis and biological activity of amino acid derivatives of avarone and its model compound.,  23  (21): [PMID:26476666] [10.1016/j.bmc.2015.09.044]
    219. Mehta V, Athar M, Jha PC, Panchal M, Modi K, Jain VK..  (2016)  Efficiently functionalized oxacalix[4]arenes: Synthesis, characterization and exploration of their biological profile as novel HDAC inhibitors.,  26  (3): [PMID:26725026] [10.1016/j.bmcl.2015.12.044]
    220. Ajdačić V, Senerovic L, Vranić M, Pekmezovic M, Arsic-Arsnijevic V, Veselinovic A, Veselinovic J, Šolaja BA, Nikodinovic-Runic J, Opsenica IM..  (2016)  Synthesis and evaluation of thiophene-based guanylhydrazones (iminoguanidines) efficient against panel of voriconazole-resistant fungal isolates.,  24  (6): [PMID:26867487] [10.1016/j.bmc.2016.01.058]
    221. Karad SC, Purohit VB, Thakor P, Thakkar VR, Raval DK..  (2016)  Novel morpholinoquinoline nucleus clubbed with pyrazoline scaffolds: Synthesis, antibacterial, antitubercular and antimalarial activities.,  112  [PMID:26900659] [10.1016/j.ejmech.2016.02.016]
    222. Tiwari S, Pathak P, Sagar R..  (2016)  Efficient synthesis of new 2,3-dihydrooxazole-spirooxindoles hybrids as antimicrobial agents.,  26  (10): [PMID:27040662] [10.1016/j.bmcl.2016.03.093]
    223. Hafez HN, El-Gazzar AR, Al-Hussain SA..  (2016)  Novel pyrazole derivatives with oxa/thiadiazolyl, pyrazolyl moieties and pyrazolo[4,3-d]-pyrimidine derivatives as potential antimicrobial and anticancer agents.,  26  (10): [PMID:27080187] [10.1016/j.bmcl.2016.03.117]
    224. Jeremić M, Pešić M, Dinić J, Banković J, Novaković I, Šegan D, Sladić D..  (2016)  Simple avarone mimetics as selective agents against multidrug resistant cancer cells.,  118  [PMID:27128177] [10.1016/j.ejmech.2016.04.011]
    225. Raghavendra KR, Renuka N, Kameshwar VH, Srinivasan B, Ajay Kumar K, Shashikanth S..  (2016)  Synthesis of lignan conjugates via cyclopropanation: Antimicrobial and antioxidant studies.,  26  (15): [PMID:27318538] [10.1016/j.bmcl.2016.06.005]
    226. WHO Anatomical Therapeutic Chemical Classification, 
    227. British National Formulary (72nd edition), 
    228. Helfenstein A, Vahermo M, Nawrot DA, Demirci F, İşcan G, Krogerus S, Yli-Kauhaluoma J, Moreira VM, Tammela P..  (2017)  Antibacterial profiling of abietane-type diterpenoids.,  25  (1): [PMID:27793449] [10.1016/j.bmc.2016.10.019]
    229. DrugMatrix,  [10.6019/CHEMBL3885881]
    230. Richter C, Helaly SE, Thongbai B, Hyde KD, Stadler M..  (2016)  Pyristriatins A and B: Pyridino-Cyathane Antibiotics from the Basidiomycete Cyathus cf. striatus.,  79  (6): [PMID:27231731] [10.1021/acs.jnatprod.6b00194]
    231. Karad SC, Purohit VB, Thummar RP, Vaghasiya BK, Kamani RD, Thakor P, Thakkar VR, Thakkar SS, Ray A, Raval DK..  (2017)  Synthesis and biological screening of novel 2-morpholinoquinoline nucleus clubbed with 1,2,4-oxadiazole motifs.,  126  [PMID:27988464] [10.1016/j.ejmech.2016.12.016]
    232. Chen M, Suzuki A, Thakkar S, Yu K, Hu C, Tong W..  (2016)  DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.,  21  (4): [PMID:26948801] [10.1016/j.drudis.2016.02.015]
    233. Jose G, Suresha Kumara TH, Sowmya HBV, Sriram D, Guru Row TN, Hosamani AA, More SS, Janardhan B, Harish BG, Telkar S, Ravikumar YS..  (2017)  Synthesis, molecular docking, antimycobacterial and antimicrobial evaluation of new pyrrolo[3,2-c]pyridine Mannich bases.,  131  [PMID:28340368] [10.1016/j.ejmech.2017.03.015]
    234. Thakkar SS, Thakor P, Ray A, Doshi H, Thakkar VR..  (2017)  Benzothiazole analogues: Synthesis, characterization, MO calculations with PM6 and DFT, in silico studies and in vitro antimalarial as DHFR inhibitors and antimicrobial activities.,  25  (20): [PMID:28789907] [10.1016/j.bmc.2017.07.057]
    235. Thakkar SS, Thakor P, Doshi H, Ray A..  (2017)  1,2,4-Triazole and 1,3,4-oxadiazole analogues: Synthesis, MO studies, in silico molecular docking studies, antimalarial as DHFR inhibitor and antimicrobial activities.,  25  (15): [PMID:28634040] [10.1016/j.bmc.2017.05.054]
    236. Lokeshwari DM, Achutha DK, Srinivasan B, Shivalingegowda N, Krishnappagowda LN, Kariyappa AK..  (2017)  Synthesis of novel 2-pyrazoline analogues with potent anti-inflammatory effect mediated by inhibition of phospholipase A2: Crystallographic, in silico docking and QSAR analysis.,  27  (16): [PMID:28676270] [10.1016/j.bmcl.2017.06.063]
    237. Noumeur SR, Helaly SE, Jansen R, Gereke M, Stradal TEB, Harzallah D, Stadler M..  (2017)  Preussilides A-F, Bicyclic Polyketides from the Endophytic Fungus Preussia similis with Antiproliferative Activity.,  80  (5): [PMID:28398049] [10.1021/acs.jnatprod.7b00064]
    238. Silva GH, Zeraik ML, de Oliveira CM, Teles HL, Trevisan HC, Pfenning LH, Nicolli CP, Young MCM, Mascarenhas YP, Abreu LM, Saraiva AC, Medeiros AI, Bolzani VDS, Araujo AR..  (2017)  Lactone Derivatives Produced by a Phaeoacremonium sp., an Endophytic Fungus from Senna spectabilis.,  80  (5): [PMID:28425292] [10.1021/acs.jnatprod.5b00828]
    239. Mostofi M, Mohammadi Ziarani G, Lashgari N..  (2018)  Design, synthesis and biological evaluation of benzofuran appended benzothiazepine derivatives as inhibitors of butyrylcholinesterase and antimicrobial agents.,  26  (12): [PMID:29866481] [10.1016/j.bmc.2018.02.049]
    240. Rios MY, Navarro V, Ramírez-Cisneros MÁ, Salazar-Rios E..  (2017)  Sulfur-Containing Aristoloxazines and Other Constituents of the Roots of Aristolochia orbicularis.,  80  (12): [PMID:29210585] [10.1021/acs.jnatprod.7b00226]
    241. Sandargo B, Thongbai B, Stadler M, Surup F..  (2018)  Cysteine-Derived Pleurotin Congeners from the Nematode-Trapping Basidiomycete Hohenbuehelia grisea.,  81  (2): [PMID:29356520] [10.1021/acs.jnatprod.7b00713]
    242. Chepkirui C, Yuyama KT, Wanga LA, Decock C, Matasyoh JC, Abraham WR, Stadler M..  (2018)  Microporenic Acids A-G, Biofilm Inhibitors, and Antimicrobial Agents from the Basidiomycete Microporus Species.,  81  (4): [PMID:29489350] [10.1021/acs.jnatprod.7b00764]
    243. Unpublished dataset, 
    244. Bernhard Ellinger, Denisa Bojkova, Andrea Zaliani, Jindrich Cinatl, Carsten Claussen, Sandra Westhaus, Jeanette Reinshagen, Maria Kuzikov, Markus Wolf, Gerd Geisslinger, Philip Gribbon, Sandra Ciesek.  (2020)  Identification of inhibitors of SARS-CoV-2 in-vitro cellular toxicity in human (Caco-2) cells using a large scale drug repurposing collection,  [10.21203/rs.3.rs-23951/v1]
    245. Cheng T, Chepkirui C, Decock C, Matasyoh JC, Stadler M..  (2019)  Sesquiterpenes from an Eastern African Medicinal Mushroom Belonging to the Genus Sanghuangporus.,  82  (5): [PMID:31001977] [10.1021/acs.jnatprod.8b01086]
    246. Messaoudi O, Sudarman E, Bendahou M, Jansen R, Stadler M, Wink J..  (2019)  Kenalactams A-E, Polyene Macrolactams Isolated from Nocardiopsis CG3.,  82  (5): [PMID:31021629] [10.1021/acs.jnatprod.8b00708]
    247. Ali EMH, Abdel-Maksoud MS, Oh CH..  (2019)  Thieno[2,3-d]pyrimidine as a promising scaffold in medicinal chemistry: Recent advances.,  27  (7): [PMID:30826188] [10.1016/j.bmc.2019.02.044]
    248. Gao F, Wang T, Xiao J, Huang G..  (2019)  Antibacterial activity study of 1,2,4-triazole derivatives.,  173  [PMID:31009913] [10.1016/j.ejmech.2019.04.043]
    249. Brumley D, Spencer KA, Gunasekera SP, Sauvage T, Biggs J, Paul VJ, Luesch H..  (2018)  Isolation and Characterization of Anaephenes A-C, Alkylphenols from a Filamentous Cyanobacterium ( Hormoscilla sp., Oscillatoriales).,  81  (12): [PMID:30489078] [10.1021/acs.jnatprod.8b00650]
    250. Wang SQ, Wang YF, Xu Z..  (2019)  Tetrazole hybrids and their antifungal activities.,  170  [PMID:30904780] [10.1016/j.ejmech.2019.03.023]
    251. Pathania S, Narang RK, Rawal RK..  (2019)  Role of sulphur-heterocycles in medicinal chemistry: An update.,  180  [PMID:31330449] [10.1016/j.ejmech.2019.07.043]
    252. Phukhamsakda C, Macabeo APG, Huch V, Cheng T, Hyde KD, Stadler M..  (2019)  Sparticolins A-G, Biologically Active Oxidized Spirodioxynaphthalene Derivatives from the Ascomycete Sparticola junci.,  82  (10): [PMID:31599583] [10.1021/acs.jnatprod.9b00604]
    253. Sala S, Fromont J, Gomez O, Vuong D, Lacey E, Flematti GR..  (2019)  Albanitriles A-G: Antiprotozoal Polyacetylene Nitriles from a Mycale Marine Sponge.,  82  (12): [PMID:31833368] [10.1021/acs.jnatprod.9b00840]
    254. Li HT, Zhou H, Duan RT, Li HY, Tang LH, Yang XQ, Yang YB, Ding ZT..  (2019)  Inducing Secondary Metabolite Production by Co-culture of the Endophytic Fungus Phoma sp. and the Symbiotic Fungus Armillaria sp.,  82  (4): [PMID:30785282] [10.1021/acs.jnatprod.8b00685]
    255. Maria Kuzikov, Elisa Costanzi, Jeanette Reinshagen, Francesca Esposito, Laura Vangeel, Markus Wolf, Bernhard Ellinger, Carsten Claussen, Gerd Geisslinger, Angela Corona, Daniela Iaconis, Carmine Talarico, Candida Manelfi, Rolando Cannalire, Giulia Rossetti, Jonas Gossen, Simone Albani, Francesco Musiani, Katja Herzog, Yang Ye, Barbara Giabbai, Nicola Demitri, Dirk Jochmans, Steven De Jonghe, Jasper Rymenants, Vincenzo Summa, Enzo Tramontano, Andrea R. Beccari, Pieter Leyssen, Paola Storici, Johan Neyts, Philip Gribbon, and Andrea Zaliani.  (2020)  Identification of inhibitors of SARS-Cov2 M-Pro enzymatic activity using a small molecule repurposing screen,  [10.6019/CHEMBL4495564]
    256. Andrea Zaliani, Laura Vangeel, Jeanette Reinshagen, Daniela Iaconis, Maria Kuzikov, Oliver Keminer, Markus Wolf, Bernhard Ellinger, Francesca Esposito, Angela Corona, Enzo Tramontano, Candida Manelfi, Katja Herzog, Dirk Jochmans, Steven De Jonghe, Winston Chiu, Thibault Francken, Joost Schepers, Caroline Collard, Kayvan Abbasi, Carsten Claussen , Vincenzo Summa, Andrea R. Beccari, Johan Neyts, Philip Gribbon and Pieter Leyssen.  (2020)  Cytopathic SARS-Cov2 screening on VERO-E6 cells in a large repurposing effort,  [10.6019/CHEMBL4495565]
    257. Rashamuse TJ, Harrison AT, Mosebi S, van Vuuren S, Coyanis EM, Bode ML..  (2020)  Design, synthesis and biological evaluation of imidazole and oxazole fragments as HIV-1 integrase-LEDGF/p75 disruptors and inhibitors of microbial pathogens.,  28  (1): [PMID:31753802] [10.1016/j.bmc.2019.115210]
    258. Nainwal LM, Tasneem S, Akhtar W, Verma G, Khan MF, Parvez S, Shaquiquzzaman M, Akhter M, Alam MM..  (2019)  Green recipes to quinoline: A review.,  164  [PMID:30594028] [10.1016/j.ejmech.2018.11.026]
    259. Cheng T,Chepkirui C,Decock C,Matasyoh JC,Stadler M.  (2020)  Heimiomycins A-C and Calamenens from the African Basidiomycete Heimiomyces sp.,  83  (8.0): [PMID:32786884] [10.1021/acs.jnatprod.0c00486]
    260. Pan F,El-Kashef DH,Kalscheuer R,Müller WEG,Lee J,Feldbrügge M,Mándi A,Kurtán T,Liu Z,Wu W,Proksch P.  (2020)  Cladosins L-O, new hybrid polyketides from the endophytic fungus Cladosporium sphaerospermum WBS017.,  191  [PMID:32101782] [10.1016/j.ejmech.2020.112159]
    261. Andrade JT,Lima WG,Sousa JF,Saldanha AA,Nívea Pereira De Sá null,Morais FB,Prates Silva MK,Ribeiro Viana GH,Johann S,Soares AC,Araújo LA,Antunes Fernandes SO,Cardoso VN,Siqueira Ferreira JM.  (2021)  Design, synthesis, and biodistribution studies of new analogues of marine alkaloids: Potent in vitro and in vivo fungicidal agents against Candida spp.,  210  [PMID:33316690] [10.1016/j.ejmech.2020.113048]
    262. Daraji DG,Rajani DP,Rajani SD,Pithawala EA,Jayanthi S,Patel HD.  (2021)  Structure based design, synthesis, and biological evaluation of imidazole derivatives targeting dihydropteroate synthase enzyme.,  36  [PMID:33513385] [10.1016/j.bmcl.2021.127819]
    263. Bernhard Ellinger, Justus Dick, Vanessa Lage-Rupprecht, Bruce Schultz, Andrea Zaliani, Marcin Namysl, Stephan Gebel, Ole Pless, Jeanette Reinshagen, Christian Ebeling, Alexander Esser, Marc Jacobs, Carsten Claussen, and Martin Hofmann-Apitius.  (2021)  HDAC6 screening dataset using tau-based substrate in an enzymatic assay yields selective inhibitors and activators,  [10.6019/CHEMBL4808148]
    264. Hao X, Li S, Ni J, Wang G, Li F, Li Q, Chen S, Shu J, Gan M..  (2021)  Acremopeptaibols A-F, 16-Residue Peptaibols from the Sponge-Derived Acremonium sp. IMB18-086 Cultivated with Heat-Killed Pseudomonas aeruginosa.,  84  (11.0): [PMID:34781681] [10.1021/acs.jnatprod.1c00834]
    265. Rimpiläinen T, Nunes A, Calado R, Fernandes AS, Andrade J, Ntungwe E, Spengler G, Szemerédi N, Rodrigues J, Gomes JP, Rijo P, Candeias NR..  (2021)  Increased antibacterial properties of indoline-derived phenolic Mannich bases.,  220  [PMID:33915373] [10.1016/j.ejmech.2021.113459]
    266. Garcia KYM, Phukhamsakda C, Quimque MTJ, Hyde KD, Stadler M, Stadler M, Macabeo APG..  (2021)  Catechol-Bearing Polyketide Derivatives from Sparticola junci.,  84  (7.0): [PMID:34197704] [10.1021/acs.jnatprod.1c00415]
    267. Amir A, Levin-Khalifa M, Dvash T..  (2022)  Water-Soluble Nystatin and Derivative.,  13  (2.0): [PMID:35178173] [10.1021/acsmedchemlett.1c00538]
    268. Bracegirdle J, Hou P, Nowak VV, Ackerley DF, Keyzers RA, Owen JG..  (2021)  Skyllamycins D and E, Non-Ribosomal Cyclic Depsipeptides from Lichen-Sourced Streptomyces anulatus.,  84  (9.0): [PMID:34490774] [10.1021/acs.jnatprod.1c00547]
    269. Kemkuignou BM, Moussa AY, Decock C, Stadler M..  (2022)  Terpenoids and Meroterpenoids from Cultures of Two Grass-Associated Species of Amylosporus (Basidiomycota).,  85  (4.0): [PMID:35175766] [10.1021/acs.jnatprod.1c00975]
    270. Gan D, Wang CY, Li CZ, Zhu L, Zhang XR, Ding H, Cai L, Ding Z..  (2022)  Secondary Metabolites from Annulohypoxylon sp. and Structural Revision of Emericellins A and B.,  85  (4.0): [PMID:35293746] [10.1021/acs.jnatprod.1c00922]
    271. Schrey H, Scheele T, Ulonska C, Nedder DL, Neudecker T, Spiteller P, Stadler M..  (2022)  Alliacane-Type Secondary Metabolites from Submerged Cultures of the Basidiomycete Clitocybe nebularis.,  85  (10.0): [PMID:36130285] [10.1021/acs.jnatprod.2c00554]
    272. Çiçek SS, Galarza Pérez M, Wenzel-Storjohann A, Bezerra RM, Segovia JFO, Girreser U, Kanzaki I, Tasdemir D..  (2022)  Antimicrobial Prenylated Isoflavones from the Leaves of the Amazonian Medicinal Plant Vatairea guianensis Aubl.,  85  (4.0): [PMID:35271771] [10.1021/acs.jnatprod.1c01035]
    273. Chang Y, Zhou L, Hou X, Zhu T, Pfeifer BA, Li D, He X, Zhang G, Che Q..  (2023)  Microbial Dimerization and Chlorination of Isoflavones by a Takla Makan Desert-Derived Streptomyces sp. HDN154127.,  86  (1.0): [PMID:36535025] [10.1021/acs.jnatprod.2c00669]
    274. Salehian F, Nadri H, Jalili-Baleh L, Youseftabar-Miri L, Abbas Bukhari SN, Foroumadi A, Tüylü Küçükkilinç T, Sharifzadeh M, Khoobi M..  (2021)  A review: Biologically active 3,4-heterocycle-fused coumarins.,  212  [PMID:33276991] [10.1016/j.ejmech.2020.113034]
    275. Elattar KM, El-Khateeb AY, Hamed SE..  (2022)  Insights into the recent progress in the medicinal chemistry of pyranopyrimidine analogs.,  13  (5.0): [PMID:35694689] [10.1039/d2md00076h]
    276. Sutherland JJ, Yonchev D, Fekete A, Urban L..  (2023)  A preclinical secondary pharmacology resource illuminates target-adverse drug reaction associations of marketed drugs.,  14  (1): [PMID:37468498] [10.1038/s41467-023-40064-9]