L-Ribose

ID: ALA4798865

Cas Number: 41546-21-8

PubChem CID: 11804933

Product Number: T679286, Order Now?

Max Phase: Preclinical

Molecular Formula: C5H10O5

Molecular Weight: 150.13

Molecule Type: Unknown

Names and Identifiers

Canonical SMILES:  OC[C@@H]1OC(O)[C@@H](O)[C@H]1O

Standard InChI:  InChI=1S/C5H10O5/c6-1-2-3(7)4(8)5(9)10-2/h2-9H,1H2/t2-,3-,4-,5?/m0/s1

Standard InChI Key:  HMFHBZSHGGEWLO-OWMBCFKOSA-N

Molfile:  

 
     RDKit          2D

 10 10  0  0  0  0  0  0  0  0999 V2000
    4.5209  -12.2461    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.3459  -12.2461    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    5.6027  -11.4619    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    4.9334  -10.9751    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.2684  -11.4619    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    3.4836  -11.2073    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    6.3877  -11.2081    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.0351  -12.9129    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    5.8301  -12.9140    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.3117  -10.4004    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0
  2  3  1  0
  3  4  1  0
  4  5  1  0
  5  1  1  0
  5  6  1  6
  3  7  1  0
  1  8  1  1
  2  9  1  1
  6 10  1  0
M  END

Alternative Forms

1. Parent:

   

   ALA4798865

   (3S,4R,5S)-5-(hydroxymethyl)tetrahydrofuran-2,3,4-triol

Molecule Features

Natural Product: Yes

Oral: No

Chemical Probe: No

Parenteral: No

Molecule Type: Unknown

Topical: No

First In Class: No

Black Box: No

Chirality: No

Availability: No

Prodrug: No

Calculated Properties

Molecular Weight: 150.13

Molecular Weight (Monoisotopic): 150.0528

AlogP: -2.58

#Rotatable Bonds: 1

Polar Surface Area: 90.15

Molecular Species: NEUTRAL

HBA: 5

HBD: 4

#RO5 Violations: ┄

HBA (Lipinski): 5

HBD (Lipinski): 4

#RO5 Violations (Lipinski): ┄

CX Acidic pKa: 11.31

CX Basic pKa: ┄

CX LogP: -2.30

CX LogD: -2.30

Aromatic Rings: ┄

Heavy Atoms: 10

QED Weighted: 0.33

Np Likeness Score: 2.88

References

1. Sakoguchi H,Yoshihara A,Shintani T,Okuma K,Izumori K,Sato M.  (2016)  Growth inhibitory effect of D-arabinose against the nematode Caenorhabditis elegans: Discovery of a novel bioactive monosaccharide.,  26  (3.0): [PMID:26791015] [10.1016/j.bmcl.2016.01.007]

Source

Source(1):

• Scientific Literature