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| 3. Rasolofonjatovo E, Provot O, Hamze A, Rodrigo J, Bignon J, Wdzieczak-Bakala J, Desravines D, Dubois J, Brion JD, Alami M.. (2012) Conformationnally restricted naphthalene derivatives type isocombretastatin A-4 and isoerianin analogues: synthesis, cytotoxicity and antitubulin activity., 52 [PMID:22449653] [10.1016/j.ejmech.2012.03.001] |
| 4. Rasolofonjatovo E, Provot O, Hamze A, Rodrigo J, Bignon J, Wdzieczak-Bakala J, Lenoir C, Desravines D, Dubois J, Brion JD, Alami M.. (2013) Design, synthesis and anticancer properties of 5-arylbenzoxepins as conformationally restricted isocombretastatin A-4 analogs., 62 [PMID:23353744] [10.1016/j.ejmech.2012.12.042] |
| 5. Abuhaie CM, Bîcu E, Rigo B, Gautret P, Belei D, Farce A, Dubois J, Ghinet A.. (2013) Synthesis and anticancer activity of analogues of phenstatin, with a phenothiazine A-ring, as a new class of microtubule-targeting agents., 23 (1): [PMID:23200248] [10.1016/j.bmcl.2012.10.135] |
| 6. Soussi MA, Provot O, Bernadat G, Bignon J, Wdzieczak-Bakala J, Desravines D, Dubois J, Brion JD, Messaoudi S, Alami M.. (2014) Discovery of azaisoerianin derivatives as potential antitumors agents., 78 [PMID:24681982] [10.1016/j.ejmech.2014.03.032] |
| 7. Renko D, Provot O, Rasolofonjatovo E, Bignon J, Rodrigo J, Dubois J, Brion JD, Hamze A, Alami M.. (2015) Rapid synthesis of 4-arylchromenes from ortho-substituted alkynols: A versatile access to restricted isocombretastatin A-4 analogues as antitumor agents., 90 [PMID:25528337] [10.1016/j.ejmech.2014.12.024] |
| 8. Ghinet A, Moise IM, Rigo B, Homerin G, Farce A, Dubois J, Bîcu E.. (2016) Studies on phenothiazines: New microtubule-interacting compounds with phenothiazine A-ring as potent antineoplastic agents., 24 (10): [PMID:27073050] [10.1016/j.bmc.2016.04.001] |
| 9. Khelifi I, Naret T, Renko D, Hamze A, Bernadat G, Bignon J, Lenoir C, Dubois J, Brion JD, Provot O, Alami M.. (2017) Design, synthesis and anticancer properties of IsoCombretaQuinolines as potent tubulin assembly inhibitors., 127 [PMID:28166995] [10.1016/j.ejmech.2016.11.012] |
| 10. Pang Y, An B, Lou L, Zhang J, Yan J, Huang L, Li X, Yin S.. (2017) Design, Synthesis, and Biological Evaluation of Novel Selenium-Containing Isocombretastatins and Phenstatins as Antitumor Agents., 60 (17): [PMID:28792756] [10.1021/acs.jmedchem.7b00480] |
| 11. Song MY, Cao CY, He QR, Dong QM, Li D, Tang JJ, Gao JM.. (2017) Constructing novel dihydrofuran and dihydroisoxazole analogues of isocombretastatin-4 as tubulin polymerization inhibitors through [3+2] reactions., 25 (20): [PMID:28803799] [10.1016/j.bmc.2017.07.048] |
| 12. Naret T, Bignon J, Bernadat G, Benchekroun M, Levaique H, Lenoir C, Dubois J, Pruvost A, Saller F, Borgel D, Manoury B, Leblais V, Darrigrand R, Apcher S, Brion JD, Schmitt E, Leroux FR, Alami M, Hamze A.. (2018) A fluorine scan of a tubulin polymerization inhibitor isocombretastatin A-4: Design, synthesis, molecular modelling, and biological evaluation., 143 [PMID:29202409] [10.1016/j.ejmech.2017.11.055] |
| 13. Lamaa D, Lin HP, Zig L, Bauvais C, Bollot G, Bignon J, Levaique H, Pamlard O, Dubois J, Ouaissi M, Souce M, Kasselouri A, Saller F, Borgel D, Jayat-Vignoles C, Al-Mouhammad H, Feuillard J, Benihoud K, Alami M, Hamze A.. (2018) Design and Synthesis of Tubulin and Histone Deacetylase Inhibitor Based on iso-Combretastatin A-4., 61 (15): [PMID:30004697] [10.1021/acs.jmedchem.8b00050] |
| 14. Naret T, Khelifi I, Provot O, Bignon J, Levaique H, Dubois J, Souce M, Kasselouri A, Deroussent A, Paci A, Varela PF, Gigant B, Alami M, Hamze A.. (2019) 1,1-Diheterocyclic Ethylenes Derived from Quinaldine and Carbazole as New Tubulin-Polymerization Inhibitors: Synthesis, Metabolism, and Biological Evaluation., 62 (4): [PMID:30525602] [10.1021/acs.jmedchem.8b01386] |
| 15. Khelifi I, Naret T, Hamze A, Bignon J, Levaique H, Garcia Alvarez MC, Dubois J, Provot O, Alami M.. (2019) N,N-bis-heteroaryl methylamines: Potent anti-mitotic and highly cytotoxic agents., 168 [PMID:30818177] [10.1016/j.ejmech.2019.02.038] |
| 16. Pecnard S,Provot O,Levaique H,Bignon J,Askenatzis L,Saller F,Borgel D,Michallet S,Laisne MC,Lafanechère L,Alami M,Hamze A. (2021) Cyclic bridged analogs of isoCA-4: Design, synthesis and biological evaluation., 209 [PMID:33038796] [10.1016/j.ejmech.2020.112873] |
| 17. Shuai W,Li X,Li W,Xu F,Lu L,Yao H,Yang L,Zhu H,Xu S,Zhu Z,Xu J. (2020) Design, synthesis and anticancer properties of isocombretapyridines as potent colchicine binding site inhibitors., 197 [PMID:32339853] [10.1016/j.ejmech.2020.112308] |
| 18. Pecnard S, Hamze A, Bignon J, Prost B, Deroussent A, Gallego-Yerga L, Peláez R, Paik JY, Diederich M, Alami M, Provot O.. (2021) Anticancer properties of indole derivatives as IsoCombretastatin A-4 analogues., 223 [PMID:34171660] [10.1016/j.ejmech.2021.113656] |
| 19. Hauguel C, Ducellier S, Provot O, Ibrahim N, Lamaa D, Balcerowiak C, Letribot B, Nascimento M, Blanchard V, Askenatzis L, Levaique H, Bignon J, Baschieri F, Bauvais C, Bollot G, Renko D, Deroussent A, Prost B, Laisne MC, Michallet S, Lafanechère L, Papot S, Montagnac G, Tran C, Alami M, Apcher S, Hamze A.. (2022) Design, synthesis and biological evaluation of quinoline-2-carbonitrile-based hydroxamic acids as dual tubulin polymerization and histone deacetylases inhibitors., 240 [PMID:35797900] [10.1016/j.ejmech.2022.114573] |
