2-(4-(dimethyl(vinyl)silyl)phenyl)-1,1,1,3,3,3-hexafluoropropan-2-ol

ID: ALA5182815

Chembl Id: CHEMBL5182815

PubChem CID: 168282075

Max Phase: Preclinical

Molecular Formula: C13H14F6OSi

Molecular Weight: 328.33

Names and Identifiers

Canonical SMILES:  C=C[Si](C)(C)c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1

Standard InChI:  InChI=1S/C13H14F6OSi/c1-4-21(2,3)10-7-5-9(6-8-10)11(20,12(14,15)16)13(17,18)19/h4-8,20H,1H2,2-3H3

Standard InChI Key:  SXZWTVJONJUMMI-UHFFFAOYSA-N

Alternative Forms

1. Parent:

   

   ALA5182815

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Molecule Features

Natural Product: No

Oral: No

Chemical Probe: No

Parenteral: No

Molecule Type:

Topical: No

First In Class: No

Black Box: No

Chirality: No

Availability: No

Prodrug: No

Calculated Properties

Molecular Weight: 328.33

Molecular Weight (Monoisotopic): 328.0718

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References

1. Namba N, Noguchi-Yachide T, Matsumoto Y, Hashimoto Y, Fujii S..  (2022)  Design, synthesis and structure-activity relationship of 4-(1,1,1,3,3,3-hexafluoro-2-hydroxyisoprop-2-yl)phenylsilane derivatives as liver X receptor agonists.,  66  [PMID:35576658] [10.1016/j.bmc.2022.116792]

Source

Source(1):

• Scientific Literature