(E)-1-(3,4-dimethoxy-5-(methylselanyl)phenyl)-3-(6-methoxy-1H-indol-3-yl)-2-methylprop-2-en-1-one

ID: ALA5190895

Chembl Id: CHEMBL5190895

PubChem CID: 168285680

Max Phase: Preclinical

Molecular Formula: C22H23NO4Se

Molecular Weight: 444.39

Names and Identifiers

Canonical SMILES:  COc1ccc2c(/C=C(\C)C(=O)c3cc(OC)c(OC)c([Se]C)c3)c[nH]c2c1

Standard InChI:  InChI=1S/C22H23NO4Se/c1-13(8-15-12-23-18-11-16(25-2)6-7-17(15)18)21(24)14-9-19(26-3)22(27-4)20(10-14)28-5/h6-12,23H,1-5H3/b13-8+

Standard InChI Key:  BDJOKZTWBXWRIA-MDWZMJQESA-N

Alternative Forms

1. Parent:

   

   ALA5190895

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Molecule Features

Natural Product: No

Oral: No

Chemical Probe: No

Parenteral: No

Molecule Type:

Topical: No

First In Class: No

Black Box: No

Chirality: No

Availability: No

Prodrug: No

Calculated Properties

Molecular Weight: 444.39

Molecular Weight (Monoisotopic): 445.0792

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References

1. Yan J, Xu Y, Jin X, Zhang Q, Ouyang F, Han L, Zhan M, Li X, Liang B, Huang X..  (2022)  Structure modification and biological evaluation of indole-chalcone derivatives as anti-tumor agents through dual targeting tubulin and TrxR.,  227  [PMID:34649064] [10.1016/j.ejmech.2021.113897]

Source

Source(1):

• Scientific Literature