1,1,1,3,3,3-hexafluoro-2-(4-((2-hydroxyethyl)dimethylsilyl)phenyl)propan-2-ol

ID: ALA5196110

Chembl Id: CHEMBL5196110

PubChem CID: 168288068

Max Phase: Preclinical

Molecular Formula: C13H16F6O2Si

Molecular Weight: 346.34

Names and Identifiers

Canonical SMILES:  C[Si](C)(CCO)c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1

Standard InChI:  InChI=1S/C13H16F6O2Si/c1-22(2,8-7-20)10-5-3-9(4-6-10)11(21,12(14,15)16)13(17,18)19/h3-6,20-21H,7-8H2,1-2H3

Standard InChI Key:  NHYBMDOXHHUKTA-UHFFFAOYSA-N

Alternative Forms

1. Parent:

   

   ALA5196110

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Molecule Features

Natural Product: No

Oral: No

Chemical Probe: No

Parenteral: No

Molecule Type:

Topical: No

First In Class: No

Black Box: No

Chirality: No

Availability: No

Prodrug: No

Calculated Properties

Molecular Weight: 346.34

Molecular Weight (Monoisotopic): 346.0824

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References

1. Namba N, Noguchi-Yachide T, Matsumoto Y, Hashimoto Y, Fujii S..  (2022)  Design, synthesis and structure-activity relationship of 4-(1,1,1,3,3,3-hexafluoro-2-hydroxyisoprop-2-yl)phenylsilane derivatives as liver X receptor agonists.,  66  [PMID:35576658] [10.1016/j.bmc.2022.116792]

Source

Source(1):

• Scientific Literature