Standard InChI: InChI=1S/C30H40N4O6S/c1-20(2)18-25(33-29(36)28(35)24(31)19-21-10-6-5-7-11-21)30(37)40-17-16-32-41(38,39)27-15-9-12-22-23(27)13-8-14-26(22)34(3)4/h5-15,20,24-25,28,32,35H,16-19,31H2,1-4H3,(H,33,36)/t24-,25+,28+/m1/s1
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3.Zhang, Bin and 8 more authors. 2008-12-11 Design, synthesis, and evaluation of tricyclic, conformationally constrained small-molecule mimetics of second mitochondria-derived activator of caspases. [PMID:19012392]
4.Sun, Wei and 9 more authors. 2009-02-12 Design, synthesis, and evaluation of potent, nonpeptidic mimetics of second mitochondria-derived activator of caspases. [PMID:19138149]
5.Sun, Haiying and 6 more authors. 2010-05-15 Cyclopeptide Smac mimetics as antagonists of IAP proteins. [PMID:20443226]
6.Cai, Qian and 17 more authors. 2011-04-28 A potent and orally active antagonist (SM-406/AT-406) of multiple inhibitor of apoptosis proteins (IAPs) in clinical development for cancer treatment. [PMID:21443232]
7.Sun, Haiying and 11 more authors. 2011-05-12 Potent bivalent Smac mimetics: effect of the linker on binding to inhibitor of apoptosis proteins (IAPs) and anticancer activity. [PMID:21462933]
8.Flygare, John A JA and 41 more authors. 2012-05-10 Discovery of a potent small-molecule antagonist of inhibitor of apoptosis (IAP) proteins and clinical candidate for the treatment of cancer (GDC-0152). [PMID:22413863]
9.Sheng, Rong R and 13 more authors. 2013-05-23 A potent bivalent Smac mimetic (SM-1200) achieving rapid, complete, and durable tumor regression in mice. [PMID:23651223]
10.Zhang, Yong Y and 20 more authors. 2015-07-09 Dimeric Macrocyclic Antagonists of Inhibitor of Apoptosis Proteins for the Treatment of Cancer. [PMID:26191364]
11.Baggio, Carlo C and 8 more authors. 2018-07-26 Design of Potent pan-IAP and Lys-Covalent XIAP Selective Inhibitors Using a Thermodynamics Driven Approach. [PMID:29940121]