| 1. Alexander P, Krishnamurthy VV, Prisbe EJ.. (1996) Synthesis and antiviral activity of pyranosylphosphonic acid nucleotide analogues., 39 (6): [PMID:8632439] [10.1021/jm950788+] |
| 2. Wu J, Schneller SW, Seley KL.. (1997) Carbocyclic oxetanocins lacking the C-3' methylene., 40 (9): [PMID:9135038] [10.1021/jm960770e] |
| 3. Bronson JJ, Ghazzouli I, Hitchcock MJ, Webb RR, Martin JC.. (1989) Synthesis and antiviral activity of the nucleotide analogue (S)-1-[3-hydroxy-2-(phosphonylmethoxy)propyl]cytosine., 32 (7): [PMID:2544723] [10.1021/jm00127a010] |
| 4. Kundu NG, Mahanty JS, Spears C, Andrei G, Snoeck R, Balzarini J, De Clercq E. (1995) Palladium-catalyzed synthesis of (E)-5-(2-acylvinyl)-2-deoxyuridines and their antiviral and cytotoxic activities, 5 (15): [10.1016/0960-894X(95)00278-2] |
| 5. McGuigan C, Pathirana RN, Snoeck R, Andrei G, De Clercq E, Balzarini J.. (2004) Discovery of a new family of inhibitors of human cytomegalovirus (HCMV) based upon lipophilic alkyl furano pyrimidine dideoxy nucleosides: action via a novel non-nucleosidic mechanism., 47 (7): [PMID:15027877] [10.1021/jm030857h] |
| 6. Kim D, Kim Y, Kim KH. (1994) Synthesis and anti-HCMV activity of 9-[[(ethoxyhydroxyphosphinyl)methoxy]methoxy]guanine, an isostere of PMEG monoethyl ester, 4 (18): [10.1016/S0960-894X(00)80078-5] |
| 7. Gerona-Navarro G, Pérez de Vega MJ, García-López MT, Andrei G, Snoeck R, Balzarini J, De Clercq E, González-Muñiz R.. (2004) Synthesis and anti-HCMV activity of 1-acyl-beta-lactams and 1-acylazetidines derived from phenylalanine., 14 (9): [PMID:15081019] [10.1016/j.bmcl.2004.02.010] |
| 8. Garuti L, Roberti M, De Clercq E.. (2002) Synthesis and antiviral/antiproliferative activity of some N-sulphonylbenzimidazoles., 12 (19): [PMID:12217359] [10.1016/s0960-894x(02)00535-8] |
| 9. Gueiffier A, Lhassani M, Elhakmaoui A, Snoeck R, Andrei G, Chavignon O, Teulade JC, Kerbal A, Essassi EM, Debouzy JC, Witvrouw M, Blache Y, Balzarini J, De Clercq E, Chapat JP.. (1996) Synthesis of acyclo-C-nucleosides in the imidazo[1,2-a]pyridine and pyrimidine series as antiviral agents., 39 (14): [PMID:8709116] [10.1021/jm9507901] |
| 10. Martinez A, Gil C, Perez C, Castro A, Prieto C, Otero J, Andrei G, Snoeck R, Balzarini J, De Clercq E.. (2000) Nonnucleoside human cytomegalovirus inhibitors: synthesis and antiviral evaluation of (chlorophenylmethyl)benzothiadiazine dioxide derivatives., 43 (17): [PMID:10966745] [10.1021/jm000118q] |
| 11. Nguyen-Ba P, Turcotte N, Yuen L, Bédard J, Quimpère M, Chan L.. (1998) Identification of novel nucleotide phosphonate analogs with potent anti-HCMV activity., 8 (24): [PMID:9934471] [10.1016/s0960-894x(98)00649-0] |
| 12. Barral K, Hider RC, Balzarini J, Neyts J, De Clercq E, Camplo M.. (2003) Synthesis and antiviral evaluation of 3-hydroxy-2-methylpyridin-4-one dideoxynucleoside derivatives., 13 (24): [PMID:14643328] [10.1016/j.bmcl.2003.09.033] |
| 13. Kolocouris A, Dimas K, Pannecouque C, Witvrouw M, Foscolos GB, Stamatiou G, Fytas G, Zoidis G, Kolocouris N, Andrei G, Snoeck R, De Clercq E.. (2002) New 2-(1-adamantylcarbonyl)pyridine and 1-acetyladamantane thiosemicarbazones-thiocarbonohydrazones: cell growth inhibitory, antiviral and antimicrobial activity evaluation., 12 (5): [PMID:11858989] [10.1016/s0960-894x(01)00838-1] |
| 14. Wang J, Froeyen M, Hendrix C, Andrei G, Snoeck R, De Clercq E, Herdewijn P.. (2000) The cyclohexene ring system as a furanose mimic: synthesis and antiviral activity of both enantiomers of cyclohexenylguanine., 43 (4): [PMID:10691698] [10.1021/jm991171l] |
| 15. Opacić N, Barbarić M, Zorc B, Cetina M, Nagl A, Frković D, Kralj M, Pavelić K, Balzarini J, Andrei G, Snoeck R, De Clercq E, Raić-Malić S, Mintas M.. (2005) The novel L- and D-amino acid derivatives of hydroxyurea and hydantoins: synthesis, X-ray crystal structure study, and cytostatic and antiviral activity evaluations., 48 (2): [PMID:15658861] [10.1021/jm040869i] |
| 16. Barbarić M, Ursić S, Pilepić V, Zorc B, Hergold-Brundić A, Nagl A, Grdisa M, Pavelić K, Snoeck R, Andrei G, Balzarini J, De Clercq E, Mintas M.. (2005) Synthesis, X-ray crystal structure study, and cytostatic and antiviral evaluation of the novel cycloalkyl-N-aryl-hydroxamic acids., 48 (3): [PMID:15689173] [10.1021/jm040878r] |
| 17. Falardeau G, Lachance H, St-Pierre A, Yannopoulos CG, Drouin M, Bédard J, Chan L.. (2005) Design and synthesis of a potent macrocyclic 1,6-naphthyridine anti-human cytomegalovirus (HCMV) inhibitors., 15 (6): [PMID:15745823] [10.1016/j.bmcl.2005.01.050] |
| 18. Gerona-Navarro G, Pérez de Vega MJ, García-López MT, Andrei G, Snoeck R, De Clercq E, Balzarini J, González-Muñiz R.. (2005) From 1-acyl-beta-lactam human cytomegalovirus protease inhibitors to 1-benzyloxycarbonylazetidines with improved antiviral activity. A straightforward approach to convert covalent to noncovalent inhibitors., 48 (7): [PMID:15801851] [10.1021/jm0492812] |
| 19. Pirrung MC, Pansare SV, Sarma KD, Keith KA, Kern ER.. (2005) Combinatorial optimization of isatin-beta-thiosemicarbazones as anti-poxvirus agents., 48 (8): [PMID:15828843] [10.1021/jm049147h] |
| 20. Arumugham B, Kim HJ, Prichard MN, Kern ER, Chu CK.. (2006) Synthesis and antiviral activity of 7-deazaneplanocin A against orthopoxviruses (vaccinia and cowpox virus)., 16 (2): [PMID:16275078] [10.1016/j.bmcl.2005.10.007] |
| 21. Barral K, Balzarini J, Neyts J, De Clercq E, Hider RC, Camplo M.. (2006) Synthesis and antiviral evaluation of cyclic and acyclic 2-methyl-3-hydroxy-4-pyridinone nucleoside derivatives., 49 (1): [PMID:16392791] [10.1021/jm0504306] |
| 22. Cho JH, Bernard DL, Sidwell RW, Kern ER, Chu CK.. (2006) Synthesis of cyclopentenyl carbocyclic nucleosides as potential antiviral agents against orthopoxviruses and SARS., 49 (3): [PMID:16451078] [10.1021/jm0509750] |
| 23. Guillerm G, Muzard M, Glapski C, Pilard S, De Clercq E.. (2006) Inactivation of S-adenosyl-L-homocysteine hydrolase by 6'-cyano-5',6'-didehydro-6'-deoxyhomoadenosine and 6'-chloro-6'-cyano-5',6'-didehydro-6'-deoxyhomoadenosine. Antiviral and cytotoxic effects., 49 (4): [PMID:16480257] [10.1021/jm051023x] |
| 24. Beadle JR, Wan WB, Ciesla SL, Keith KA, Hartline C, Kern ER, Hostetler KY.. (2006) Synthesis and antiviral evaluation of alkoxyalkyl derivatives of 9-(S)-(3-hydroxy-2-phosphonomethoxypropyl)adenine against cytomegalovirus and orthopoxviruses., 49 (6): [PMID:16539388] [10.1021/jm050473m] |
| 25. Fan X, Zhang X, Zhou L, Keith KA, Kern ER, Torrence PF.. (2006) A pyrimidine-pyrazolone nucleoside chimera with potent in vitro anti-orthopoxvirus activity., 16 (12): [PMID:16603351] [10.1016/j.bmcl.2006.03.043] |
| 26. Fan X, Zhang X, Zhou L, Keith KA, Kern ER, Torrence PF.. (2006) 5-(Dimethoxymethyl)-2'-deoxyuridine: a novel gem diether nucleoside with anti-orthopoxvirus activity., 49 (11): [PMID:16722657] [10.1021/jm0601710] |
| 27. Fan X, Zhang X, Zhou L, Keith KA, Prichard MN, Kern ER, Torrence PF.. (2006) Toward orthopoxvirus countermeasures: a novel heteromorphic nucleoside of unusual structure., 49 (14): [PMID:16821766] [10.1021/jm060404n] |
| 28. Cushing TD, Adrian J, Chen X, DiMaio H, Doughan B, Flygare J, Liang L, Mayorga V, Miao S, Mellon H, Peterson MG, Powers JP, Spector F, Stein C, Wright M, Xu D, Ye Q, Jaen J.. (2006) Discovery of a novel series of inhibitors of human cytomegalovirus primase., 16 (18): [PMID:16814545] [10.1016/j.bmcl.2006.06.066] |
| 29. Scott GM, Weinberg A, Rawlinson WD, Chou S.. (2007) Multidrug resistance conferred by novel DNA polymerase mutations in human cytomegalovirus isolates., 51 (1): [PMID:17043128] [10.1128/aac.00633-06] |
| 30. Quenelle DC, Buller RM, Parker S, Keith KA, Hruby DE, Jordan R, Kern ER.. (2007) Efficacy of delayed treatment with ST-246 given orally against systemic orthopoxvirus infections in mice., 51 (2): [PMID:17116683] [10.1128/aac.00879-06] |
| 31. Krecmerová M, Holý A, Pískala A, Masojídková M, Andrei G, Naesens L, Neyts J, Balzarini J, De Clercq E, Snoeck R.. (2007) Antiviral activity of triazine analogues of 1-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]cytosine (cidofovir) and related compounds., 50 (5): [PMID:17298047] [10.1021/jm061281+] |
| 32. Cristofoli WA, Wiebe LI, De Clercq E, Andrei G, Snoeck R, Balzarini J, Knaus EE.. (2007) 5-alkynyl analogs of arabinouridine and 2'-deoxyuridine: cytostatic activity against herpes simplex virus and varicella-zoster thymidine kinase gene-transfected cells., 50 (12): [PMID:17518459] [10.1021/jm0701472] |
| 33. Prekupec S, Makuc D, Plavec J, Suman L, Kralj M, Pavelić K, Balzarini J, Clercq ED, Mintas M, Raić-Malić S.. (2007) Novel C-6 fluorinated acyclic side chain pyrimidine derivatives: synthesis, (1)H and (13)C NMR conformational studies, and antiviral and cytostatic evaluations., 50 (13): [PMID:17539622] [10.1021/jm0614329] |
| 34. Chen X, Adrian J, Cushing T, Dimaio H, Liang L, Mayorga V, Miao S, Peterson MG, Powers JP, Spector F, Stein C, Wright M, Xu D, Ye Q, Jaen J.. (2007) SAR studies on a novel series of human cytomegalovirus primase inhibitors., 17 (8): [PMID:17329103] [10.1016/j.bmcl.2007.01.109] |
| 35. Gazivoda T, Sokcević M, Kralj M, Suman L, Pavelić K, De Clercq E, Andrei G, Snoeck R, Balzarini J, Mintas M, Raić-Malić S.. (2007) Synthesis and antiviral and cytostatic evaluations of the new C-5 substituted pyrimidine and furo[2,3-d]pyrimidine 4',5'-didehydro-L-ascorbic acid derivatives., 50 (17): [PMID:17672445] [10.1021/jm070324z] |
| 36. Krecmerová M, Holý A, Pohl R, Masojídková M, Andrei G, Naesens L, Neyts J, Balzarini J, De Clercq E, Snoeck R.. (2007) Ester prodrugs of cyclic 1-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]-5-azacytosine: synthesis and antiviral activity., 50 (23): [PMID:17948980] [10.1021/jm0707166] |
| 37. Véron JB, Enguehard-Gueiffier C, Snoeck R, Andrei G, De Clercq E, Gueiffier A.. (2007) Influence of 6 or 8-substitution on the antiviral activity of 3-phenethylthiomethylimidazo[1,2-a]pyridine against human cytomegalovirus (HCMV) and varicella-zoster virus (VZV)., 15 (22): [PMID:17869124] [10.1016/j.bmc.2007.03.061] |
| 38. Prichard MN, Keith KA, Johnson MP, Harden EA, McBrayer A, Luo M, Qiu S, Chattopadhyay D, Fan X, Torrence PF, Kern ER.. (2007) Selective phosphorylation of antiviral drugs by vaccinia virus thymidine kinase., 51 (5): [PMID:17325220] [10.1128/aac.01447-06] |
| 39. Lebeau I, Andrei G, Krecmerová M, De Clercq E, Holy A, Snoeck R.. (2007) Inhibitory activities of three classes of acyclic nucleoside phosphonates against murine polyomavirus and primate simian virus 40 strains., 51 (6): [PMID:17420214] [10.1128/aac.01422-06] |
| 40. Focher F, Lossani A, Verri A, Spadari S, Maioli A, Gambino JJ, Wright GE, Eberle R, Black DH, Medveczky P, Medveczky M, Shugar D.. (2007) Sensitivity of monkey B virus (Cercopithecine herpesvirus 1) to antiviral drugs: role of thymidine kinase in antiviral activities of substrate analogs and acyclonucleosides., 51 (6): [PMID:17438061] [10.1128/aac.01284-06] |
| 41. Chou S, Marousek GI, Van Wechel LC, Li S, Weinberg A.. (2007) Growth and drug resistance phenotypes resulting from cytomegalovirus DNA polymerase region III mutations observed in clinical specimens., 51 (11): [PMID:17709468] [10.1128/aac.00736-07] |
| 42. de Castro S, Peromingo MT, Naesens L, Andrei G, Snoeck R, Balzarini J, Velázquez S, Camarasa MJ.. (2008) 4"-Benzoylureido-TSAO derivatives as potent and selective non-nucleoside HCMV inhibitors. Structure-activity relationship and mechanism of antiviral action., 51 (18): [PMID:18707089] [10.1021/jm800050t] |
| 43. Dzimbeg G, Zorc B, Kralj M, Ester K, Pavelić K, Andrei G, Snoeck R, Balzarini J, De Clercq E, Mintas M.. (2008) The novel primaquine derivatives of N-alkyl, cycloalkyl or aryl urea: synthesis, cytostatic and antiviral activity evaluations., 43 (6): [PMID:17961851] [10.1016/j.ejmech.2007.09.001] |
| 44. Ciustea M, Silverman JE, Druck Shudofsky AM, Ricciardi RP.. (2008) Identification of non-nucleoside DNA synthesis inhibitors of vaccinia virus by high-throughput screening., 51 (20): [PMID:18808105] [10.1021/jm800366g] |
| 45. Shen W, Kim JS, Kish PE, Zhang J, Mitchell S, Gentry BG, Breitenbach JM, Drach JC, Hilfinger J.. (2009) Design and synthesis of vidarabine prodrugs as antiviral agents., 19 (3): [PMID:19097789] [10.1016/j.bmcl.2008.12.031] |
| 46. Küçükgüzel I, Tatar E, Küçükgüzel SG, Rollas S, De Clercq E.. (2008) Synthesis of some novel thiourea derivatives obtained from 5-[(4-aminophenoxy)methyl]-4-alkyl/aryl-2,4-dihydro-3H-1,2,4-triazole-3-thiones and evaluation as antiviral/anti-HIV and anti-tuberculosis agents., 43 (2): [PMID:17583388] [10.1016/j.ejmech.2007.04.010] |
| 47. Ramsden NL, Buetow L, Dawson A, Kemp LA, Ulaganathan V, Brenk R, Klebe G, Hunter WN.. (2009) A structure-based approach to ligand discovery for 2C-methyl-D-erythritol-2,4-cyclodiphosphate synthase: a target for antimicrobial therapy., 52 (8): [PMID:19320487] [10.1021/jm801475n] |
| 48. Quenelle DC, Prichard MN, Keith KA, Hruby DE, Jordan R, Painter GR, Robertson A, Kern ER.. (2007) Synergistic efficacy of the combination of ST-246 with CMX001 against orthopoxviruses., 51 (11): [PMID:17724153] [10.1128/aac.00762-07] |
| 49. Quenelle DC, Collins DJ, Herrod BP, Keith KA, Trahan J, Beadle JR, Hostetler KY, Kern ER.. (2007) Effect of oral treatment with hexadecyloxypropyl-[(S)-9-(3-hydroxy-2- phosphonylmethoxypropyl)adenine] [(S)-HPMPA] or octadecyloxyethyl-(S)-HPMPA on cowpox or vaccinia virus infections in mice., 51 (11): [PMID:17846137] [10.1128/aac.00184-07] |
| 50. Duraffour S, Snoeck R, Krecmerová M, van Den Oord J, De Vos R, Holy A, Crance JM, Garin D, De Clercq E, Andrei G.. (2007) Activities of several classes of acyclic nucleoside phosphonates against camelpox virus replication in different cell culture models., 51 (12): [PMID:17893157] [10.1128/aac.00838-07] |
| 51. Véron JB, Allouchi H, Enguehard-Gueiffier C, Snoeck R, Andrei G, De Clercq E, Gueiffier A.. (2008) Influence of 6- or 8-substitution on the antiviral activity of 3-arylalkylthiomethylimidazo[1,2-a]pyridine against human cytomegalovirus (CMV) and varicella-zoster virus (VZV): part II., 16 (21): [PMID:18835175] [10.1016/j.bmc.2008.09.027] |
| 52. De Castro S, García-Aparicio C, Andrei G, Snoeck R, Balzarini J, Camarasa MJ, Velázquez S.. (2009) 4-Benzyloxy-gamma-sultone derivatives: discovery of a novel family of non-nucleoside inhibitors of human cytomegalovirus and varicella zoster virus., 52 (6): [PMID:19226140] [10.1021/jm8014662] |
| 53. Prado-Prado FJ, Martinez de la Vega O, Uriarte E, Ubeira FM, Chou KC, González-Díaz H.. (2009) Unified QSAR approach to antimicrobials. 4. Multi-target QSAR modeling and comparative multi-distance study of the giant components of antiviral drug-drug complex networks., 17 (2): [PMID:19112024] [10.1016/j.bmc.2008.11.075] |
| 54. Prado-Prado FJ, Martinez de la Vega O, Uriarte E, Ubeira FM, Chou KC, González-Díaz H.. (2009) Unified QSAR approach to antimicrobials. 4. Multi-target QSAR modeling and comparative multi-distance study of the giant components of antiviral drug-drug complex networks., 17 (2): [PMID:19112024] [10.1016/j.bmc.2008.11.075] |
| 55. Piscitelli F, Coluccia A, Brancale A, La Regina G, Sansone A, Giordano C, Balzarini J, Maga G, Zanoli S, Samuele A, Cirilli R, La Torre F, Lavecchia A, Novellino E, Silvestri R.. (2009) Indolylarylsulfones bearing natural and unnatural amino acids. Discovery of potent inhibitors of HIV-1 non-nucleoside wild type and resistant mutant strains reverse transcriptase and coxsackie B4 virus., 52 (7): [PMID:19281225] [10.1021/jm801470b] |
| 56. Sharma D, Narasimhan B, Kumar P, Judge V, Narang R, De Clercq E, Balzarini J.. (2009) Synthesis, antimicrobial and antiviral evaluation of substituted imidazole derivatives., 44 (6): [PMID:18851889] [10.1016/j.ejmech.2008.08.010] |
| 57. Varma MV, Feng B, Obach RS, Troutman MD, Chupka J, Miller HR, El-Kattan A.. (2009) Physicochemical determinants of human renal clearance., 52 (15): [PMID:19445515] [10.1021/jm900403j] |
| 58. Ostrowski T, Golankiewicz B, De Clercq E, Andrei G, Snoeck R.. (2009) Synthesis and anti-VZV activity of 6-heteroaryl derivatives of tricyclic acyclovir and 9-{[cis-1',2'-bis(hydroxymethyl)cycloprop-1'-yl]methyl}guanine analogues., 44 (8): [PMID:19339082] [10.1016/j.ejmech.2009.03.005] |
| 59. Karakuş S, Güniz Küçükgüzel S, Küçükgüzel I, De Clercq E, Pannecouque C, Andrei G, Snoeck R, Sahin F, Bayrak OF.. (2009) Synthesis, antiviral and anticancer activity of some novel thioureas derived from N-(4-nitro-2-phenoxyphenyl)-methanesulfonamide., 44 (9): [PMID:19324473] [10.1016/j.ejmech.2009.02.030] |
| 60. el-Sabbagh OI, Baraka MM, Ibrahim SM, Pannecouque C, Andrei G, Snoeck R, Balzarini J, Rashad AA.. (2009) Synthesis and antiviral activity of new pyrazole and thiazole derivatives., 44 (9): [PMID:19419804] [10.1016/j.ejmech.2009.03.038] |
| 61. Jordão AK, Afonso PP, Ferreira VF, de Souza MC, Almeida MC, Beltrame CO, Paiva DP, Wardell SM, Wardell JL, Tiekink ER, Damaso CR, Cunha AC.. (2009) Antiviral evaluation of N-amino-1,2,3-triazoles against Cantagalo virus replication in cell culture., 44 (9): [PMID:19481841] [10.1016/j.ejmech.2009.04.046] |
| 62. Varma MV, Obach RS, Rotter C, Miller HR, Chang G, Steyn SJ, El-Kattan A, Troutman MD.. (2010) Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination., 53 (3): [PMID:20070106] [10.1021/jm901371v] |
| 63. Fan X, Feng D, Qu Y, Zhang X, Wang J, Loiseau PM, Andrei G, Snoeck R, De Clercq E.. (2010) Practical and efficient synthesis of pyrano[3,2-c]pyridone, pyrano[4,3-b]pyran and their hybrids with nucleoside as potential antiviral and antileishmanial agents., 20 (3): [PMID:20064723] [10.1016/j.bmcl.2009.12.102] |
| 64. Krecmerová M, Holý A, Andrei G, Pomeisl K, Tichý T, Brehová P, Masojídková M, Dracínský M, Pohl R, Laflamme G, Naesens L, Hui H, Cihlar T, Neyts J, De Clercq E, Balzarini J, Snoeck R.. (2010) Synthesis of ester prodrugs of 9-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]-2,6-diaminopurine (HPMPDAP) as anti-poxvirus agents., 53 (19): [PMID:20809641] [10.1021/jm901828c] |
| 65. Kumar KS, Ganguly S, Veerasamy R, De Clercq E.. (2010) Synthesis, antiviral activity and cytotoxicity evaluation of Schiff bases of some 2-phenyl quinazoline-4(3)H-ones., 45 (11): [PMID:20724039] [10.1016/j.ejmech.2010.07.058] |
| 66. Obach RS, Lombardo F, Waters NJ.. (2008) Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds., 36 (7): [PMID:18426954] [10.1124/dmd.108.020479] |
| 67. Yadav S, Kumar P, De Clercq E, Balzarini J, Pannecouque C, Dewan SK, Narasimhan B.. (2010) 4-[1-(Substituted aryl/alkyl carbonyl)-benzoimidazol-2-yl]-benzenesulfonic acids: synthesis, antimicrobial activity, QSAR studies, and antiviral evaluation., 45 (12): [PMID:20971531] [10.1016/j.ejmech.2010.09.065] |
| 68. McSharry JJ, Deziel MR, Zager K, Weng Q, Drusano GL.. (2009) Pharmacodynamics of cidofovir for vaccinia virus infection in an in vitro hollow-fiber infection model system., 53 (1): [PMID:18852271] [10.1128/aac.00708-08] |
| 69. Cihlar T, Laflamme G, Fisher R, Carey AC, Vela JE, Mackman R, Ray AS.. (2009) Novel nucleotide human immunodeficiency virus reverse transcriptase inhibitor GS-9148 with a low nephrotoxic potential: characterization of renal transport and accumulation., 53 (1): [PMID:19001108] [10.1128/aac.01183-08] |
| 70. Kern ER, Prichard MN, Quenelle DC, Keith KA, Tiwari KN, Maddry JA, Secrist JA.. (2009) Activities of certain 5-substituted 4'-thiopyrimidine nucleosides against orthopoxvirus infections., 53 (2): [PMID:19029322] [10.1128/aac.01257-08] |
| 71. Prichard MN, Quenelle DC, Hartline CB, Harden EA, Jefferson G, Frederick SL, Daily SL, Whitley RJ, Tiwari KN, Maddry JA, Secrist JA, Kern ER.. (2009) Inhibition of herpesvirus replication by 5-substituted 4'-thiopyrimidine nucleosides., 53 (12): [PMID:19770274] [10.1128/aac.00417-09] |
| 72. Topalis D, Pradère U, Roy V, Caillat C, Azzouzi A, Broggi J, Snoeck R, Andrei G, Lin J, Eriksson S, Alexandre JA, El-Amri C, Deville-Bonne D, Meyer P, Balzarini J, Agrofoglio LA.. (2011) Novel antiviral C5-substituted pyrimidine acyclic nucleoside phosphonates selected as human thymidylate kinase substrates., 54 (1): [PMID:21128666] [10.1021/jm1011462] |
| 73. Talevi A, Goodarzi M, Ortiz EV, Duchowicz PR, Bellera CL, Pesce G, Castro EA, Bruno-Blanch LE.. (2011) Prediction of drug intestinal absorption by new linear and non-linear QSPR., 46 (1): [PMID:21112128] [10.1016/j.ejmech.2010.11.005] |
| 74. Wolfgang GH, Shibata R, Wang J, Ray AS, Wu S, Doerrfler E, Reiser H, Lee WA, Birkus G, Christensen ND, Andrei G, Snoeck R.. (2009) GS-9191 is a novel topical prodrug of the nucleotide analog 9-(2-phosphonylmethoxyethyl)guanine with antiproliferative activity and possible utility in the treatment of human papillomavirus lesions., 53 (7): [PMID:19398642] [10.1128/aac.00103-09] |
| 75. Montagu A, Roy V, Balzarini J, Snoeck R, Andrei G, Agrofoglio LA.. (2011) Synthesis of new C5-(1-substituted-1,2,3-triazol-4 or 5-yl)-2'-deoxyuridines and their antiviral evaluation., 46 (2): [PMID:21232828] [10.1016/j.ejmech.2010.12.017] |
| 76. Andersson EK, Strand M, Edlund K, Lindman K, Enquist PA, Spjut S, Allard A, Elofsson M, Mei YF, Wadell G.. (2010) Small-molecule screening using a whole-cell viral replication reporter gene assay identifies 2-{[2-(benzoylamino)benzoyl]amino}-benzoic acid as a novel antiadenoviral compound., 54 (9): [PMID:20585112] [10.1128/aac.00203-10] |
| 77. Fourches D, Barnes JC, Day NC, Bradley P, Reed JZ, Tropsha A.. (2010) Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species., 23 (1): [PMID:20014752] [10.1021/tx900326k] |
| 78. Matthews EJ, Kruhlak NL, Weaver JL, Benz RD, Contrera JF.. (2004) Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling., 1 (4): [PMID:16472241] [10.2174/1570163043334794] |
| 79. Unpublished dataset, |
| 80. International Transporter Consortium, Giacomini KM, Huang SM, Tweedie DJ, Benet LZ, Brouwer KL, Chu X, Dahlin A, Evers R, Fischer V, Hillgren KM, Hoffmaster KA, Ishikawa T, Keppler D, Kim RB, Lee CA, Niemi M, Polli JW, Sugiyama Y, Swaan PW, Ware JA, Wright SH, Yee SW, Zamek-Gliszczynski MJ, Zhang L.. (2010) Membrane transporters in drug development., 9 (3): [PMID:20190787] [10.1038/nrd3028] |
| 81. Kesel AJ.. (2011) Broad-spectrum antiviral activity including human immunodeficiency and hepatitis C viruses mediated by a novel retinoid thiosemicarbazone derivative., 46 (5): [PMID:21376429] [10.1016/j.ejmech.2011.02.014] |
| 82. Peterson LW, Kim JS, Kijek P, Mitchell S, Hilfinger J, Breitenbach J, Borysko K, Drach JC, Kashemirov BA, McKenna CE.. (2011) Synthesis, transport and antiviral activity of Ala-Ser and Val-Ser prodrugs of cidofovir., 21 (13): [PMID:21641218] [10.1016/j.bmcl.2011.04.126] |
| 83. Quintiliani M, Persoons L, Solaroli N, Karlsson A, Andrei G, Snoeck R, Balzarini J, McGuigan C.. (2011) Design, synthesis and biological evaluation of 2'-deoxy-2',2'-difluoro-5-halouridine phosphoramidate ProTides., 19 (14): [PMID:21696963] [10.1016/j.bmc.2011.05.037] |
| 84. Hocková D, Holý A, Andrei G, Snoeck R, Balzarini J.. (2011) Acyclic nucleoside phosphonates with a branched 2-(2-phosphonoethoxy)ethyl chain: efficient synthesis and antiviral activity., 19 (15): [PMID:21745746] [10.1016/j.bmc.2011.06.045] |
| 85. Tichý T, Andrei G, Dračínský M, Holý A, Balzarini J, Snoeck R, Krečmerová M.. (2011) New prodrugs of Adefovir and Cidofovir., 19 (11): [PMID:21565516] [10.1016/j.bmc.2011.04.016] |
| 86. Liu Z, Shi Q, Ding D, Kelly R, Fang H, Tong W.. (2011) Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps)., 7 (12): [PMID:22194678] [10.1371/journal.pcbi.1002310] |
| 87. Piotrowska DG, Balzarini J, Głowacka IE.. (2012) Design, synthesis, antiviral and cytostatic evaluation of novel isoxazolidine nucleotide analogues with a 1,2,3-triazole linker., 47 [PMID:22137458] [10.1016/j.ejmech.2011.11.021] |
| 88. Zakharova VM, Serpi M, Krylov IS, Peterson LW, Breitenbach JM, Borysko KZ, Drach JC, Collins M, Hilfinger JM, Kashemirov BA, McKenna CE.. (2011) Tyrosine-based 1-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]cytosine and -adenine ((S)-HPMPC and (S)-HPMPA) prodrugs: synthesis, stability, antiviral activity, and in vivo transport studies., 54 (16): [PMID:21812420] [10.1021/jm2001426] |
| 89. Li C, Quenelle DC, Prichard MN, Drach JC, Zemlicka J.. (2012) Synthesis and antiviral activity of 6-deoxycyclopropavir, a new prodrug of cyclopropavir., 20 (8): [PMID:22417649] [10.1016/j.bmc.2012.02.031] |
| 90. Singh K, Kaur H, Chibale K, Balzarini J, Little S, Bharatam PV.. (2012) 2-Aminopyrimidine based 4-aminoquinoline anti-plasmodial agents. Synthesis, biological activity, structure-activity relationship and mode of action studies., 52 [PMID:22459876] [10.1016/j.ejmech.2012.03.007] |
| 91. Sari O, Roy V, Balzarini J, Snoeck R, Andrei G, Agrofoglio LA.. (2012) Synthesis and antiviral evaluation of C5-substituted-(1,3-diyne)-2'-deoxyuridines., 53 [PMID:22578783] [10.1016/j.ejmech.2012.04.001] |
| 92. Öberg CT, Strand M, Andersson EK, Edlund K, Tran NP, Mei YF, Wadell G, Elofsson M.. (2012) Synthesis, biological evaluation, and structure-activity relationships of 2-[2-(benzoylamino)benzoylamino]benzoic acid analogues as inhibitors of adenovirus replication., 55 (7): [PMID:22369233] [10.1021/jm201636v] |
| 93. Tichý T, Andrei G, Snoeck R, Balzarini J, Dračínský M, Krečmerová M.. (2012) Synthesis and antiviral activities of hexadecyloxypropyl prodrugs of acyclic nucleoside phosphonates containing guanine or hypoxanthine and a (S)-HPMP or PEE acyclic moiety., 55 [PMID:22858222] [10.1016/j.ejmech.2012.07.027] |
| 94. Cihlar T, Lin DC, Pritchard JB, Fuller MD, Mendel DB, Sweet DH.. (1999) The antiviral nucleotide analogs cidofovir and adefovir are novel substrates for human and rat renal organic anion transporter 1., 56 (1): [PMID:10462545] [10.1124/mol.56.3.570] |
| 95. Ho ES, Lin DC, Mendel DB, Cihlar T.. (2000) Cytotoxicity of antiviral nucleotides adefovir and cidofovir is induced by the expression of human renal organic anion transporter 1., 11 (1): [PMID:10703662] [10.1681/asn.v113383] |
| 96. Cihlar T, Ho ES.. (2000) Fluorescence-based assay for the interaction of small molecules with the human renal organic anion transporter 1., 283 (1): [PMID:10929807] [10.1006/abio.2000.4633] |
| 97. USP Dictionary of USAN and International Names (2010 edition) and USAN registrations 2007-date, |
| 98. Pradère U, Roy V, Montagu A, Sari O, Hamada M, Balzarini J, Snoeck R, Andrei G, Agrofoglio LA.. (2012) Synthesis and antiviral evaluation of bis(POM) prodrugs of (E)-[4'-phosphono-but-2'-en-1'-yl]purine nucleosides., 57 [PMID:23047229] [10.1016/j.ejmech.2012.08.042] |
| 99. Sipos A, Török Z, Rőth E, Kiss-Szikszai A, Batta G, Bereczki I, Fejes Z, Borbás A, Ostorházi E, Rozgonyi F, Naesens L, Herczegh P.. (2012) Synthesis of isoindole and benzoisoindole derivatives of teicoplanin pseudoaglycon with remarkable antibacterial and antiviral activities., 22 (23): [PMID:23099097] [10.1016/j.bmcl.2012.09.079] |
| 100. Rashad AA, El-Sabbagh OI, Baraka MM, Ibrahim SM, Pannecouque C, Andrei G, Snoeck R, Balzarini J, Mostafa A. (2010) Design, synthesis and preliminary antiviral screening of new N-phenylpyrazole and dihydroisoxazole derivatives, 19 (9): [10.1007/s00044-009-9248-y] |
| 101. Narang R, Narasimhan B, Sharma S. (2012) (Naphthalen-1-yloxy)-acetic acid benzylidene/(1-phenyl-ethylidene)-hydrazide derivatives: synthesis, antimicrobial evaluation, and QSAR studies, 21 (9): [10.1007/s00044-011-9776-0] |
| 102. Karki SS, Kulkarni AA, Kumar S, Veliyath SK, De Clercq E, Balzarini J.. (2013) Synthesis and biological evaluation of 2-(5-substituted-1-((diethylamino)methyl)-2-oxoindolin-3-ylidene)-N-substituted-hydrazinecarbothioamides., 22 (4): [PMID:32214762] [10.1007/s00044-012-0184-x] |
| 103. Nuth M, Guan H, Zhukovskaya N, Saw YL, Ricciardi RP.. (2013) Design of potent poxvirus inhibitors of the heterodimeric processivity factor required for viral replication., 56 (8): [PMID:23527789] [10.1021/jm301735k] |
| 104. McGuigan C, Hinsinger K, Farleigh L, Pathirana RN, Bugert JJ.. (2013) Novel antiviral activity of l-dideoxy bicyclic nucleoside analogues versus vaccinia and measles viruses in vitro., 56 (3): [PMID:23320521] [10.1021/jm301778x] |
| 105. Novikov MS, Valuev-Elliston VT, Babkov DA, Paramonova MP, Ivanov AV, Gavryushov SA, Khandazhinskaya AL, Kochetkov SN, Pannecouque C, Andrei G, Snoeck R, Balzarini J, Seley-Radtke KL.. (2013) N1,N3-disubstituted uracils as nonnucleoside inhibitors of HIV-1 reverse transcriptase., 21 (5): [PMID:23357038] [10.1016/j.bmc.2012.12.027] |
| 106. Roux L, Priet S, Payrot N, Weck C, Fournier M, Zoulim F, Balzarini J, Canard B, Alvarez K.. (2013) Ester prodrugs of acyclic nucleoside thiophosphonates compared to phosphonates: synthesis, antiviral activity and decomposition study., 63 [PMID:23603046] [10.1016/j.ejmech.2013.02.039] |
| 107. Novikov MS, Babkov DA, Paramonova MP, Khandazhinskaya AL, Ozerov AA, Chizhov AO, Andrei G, Snoeck R, Balzarini J, Seley-Radtke KL.. (2013) Synthesis and anti-HCMV activity of 1-[ω-(phenoxy)alkyl]uracil derivatives and analogues thereof., 21 (14): [PMID:23743443] [10.1016/j.bmc.2013.05.009] |
| 108. Singh K, Kaur H, Chibale K, Balzarini J.. (2013) Synthesis of 4-aminoquinoline-pyrimidine hybrids as potent antimalarials and their mode of action studies., 66 [PMID:23811093] [10.1016/j.ejmech.2013.05.046] |
| 109. Hamada M, Roy V, McBrayer TR, Whitaker T, Urbina-Blanco C, Nolan SP, Balzarini J, Snoeck R, Andrei G, Schinazi RF, Agrofoglio LA.. (2013) Synthesis and broad spectrum antiviral evaluation of bis(POM) prodrugs of novel acyclic nucleosides., 67 [PMID:23911854] [10.1016/j.ejmech.2013.06.053] |
| 110. Singh K, Singh K, Balzarini J.. (2013) Regioselective synthesis of 6-substituted-2-amino-5-bromo-4(3H)-pyrimidinones and evaluation of their antiviral activity., 67 [PMID:23911856] [10.1016/j.ejmech.2013.06.036] |
| 111. PubChem BioAssay data set, |
| 112. Loddo R, Briguglio I, Corona P, Piras S, Loriga M, Paglietti G, Carta A, Sanna G, Giliberti G, Ibba C, Farci P, La Colla P.. (2014) Synthesis and antiviral activity of new phenylimidazopyridines and N-benzylidenequinolinamines derived by molecular simplification of phenylimidazo[4,5-g]quinolines., 84 [PMID:25014745] [10.1016/j.ejmech.2014.07.011] |
| 113. Kokosza K, Andrei G, Schols D, Snoeck R, Piotrowska DG.. (2015) Design, antiviral and cytostatic properties of isoxazolidine-containing amonafide analogues., 23 (13): [PMID:26001344] [10.1016/j.bmc.2015.04.079] |
| 114. Babkov DA, Khandazhinskaya AL, Chizhov AO, Andrei G, Snoeck R, Seley-Radtke KL, Novikov MS.. (2015) Toward the discovery of dual HCMV-VZV inhibitors: Synthesis, structure activity relationship analysis, and cytotoxicity studies of long chained 2-uracil-3-yl-N-(4-phenoxyphenyl)acetamides., 23 (21): [PMID:26443550] [10.1016/j.bmc.2015.09.033] |
| 115. Stipković Babić M, Makuc D, Plavec J, Martinović T, Kraljević Pavelić S, Pavelić K, Snoeck R, Andrei G, Schols D, Wittine K, Mintas M.. (2015) Novel halogenated 3-deazapurine, 7-deazapurine and alkylated 9-deazapurine derivatives of L-ascorbic or imino-L-ascorbic acid: Synthesis, antitumour and antiviral activity evaluations., 102 [PMID:26291038] [10.1016/j.ejmech.2015.08.008] |
| 116. Briguglio I, Loddo R, Laurini E, Fermeglia M, Piras S, Corona P, Giunchedi P, Gavini E, Sanna G, Giliberti G, Ibba C, Farci P, La Colla P, Pricl S, Carta A.. (2015) Synthesis, cytotoxicity and antiviral evaluation of new series of imidazo[4,5-g]quinoline and pyrido[2,3-g]quinoxalinone derivatives., 105 [PMID:26479028] [10.1016/j.ejmech.2015.10.002] |
| 117. WHO Anatomical Therapeutic Chemical Classification, |
| 118. British National Formulary (72nd edition), |
| 119. Manos-Turvey A, Al-Ashtal HA, Needham PG, Hartline CB, Prichard MN, Wipf P, Brodsky JL.. (2016) Dihydropyrimidinones and -thiones with improved activity against human polyomavirus family members., 26 (20): [PMID:27624078] [10.1016/j.bmcl.2016.08.080] |
| 120. Kang D, Zhang H, Zhou Z, Huang B, Naesens L, Zhan P, Liu X.. (2016) First discovery of novel 3-hydroxy-quinazoline-2,4(1H,3H)-diones as specific anti-vaccinia and adenovirus agents via 'privileged scaffold' refining approach., 26 (21): [PMID:27742238] [10.1016/j.bmcl.2016.09.071] |
| 121. Musella S, di Sarno V, Ciaglia T, Sala M, Spensiero A, Scala MC, Ostacolo C, Andrei G, Balzarini J, Snoeck R, Novellino E, Campiglia P, Bertamino A, Gomez-Monterrey IM.. (2016) Identification of an indol-based derivative as potent and selective varicella zoster virus (VZV) inhibitor., 124 [PMID:27639368] [10.1016/j.ejmech.2016.09.014] |
| 122. Piotrowska DG, Andrei G, Schols D, Snoeck R, Łysakowska M.. (2017) Synthesis, anti-varicella-zoster virus and anti-cytomegalovirus activity of quinazoline-2,4-diones containing isoxazolidine and phosphonate substructures., 126 [PMID:27750154] [10.1016/j.ejmech.2016.10.002] |
| 123. Kharitonova MI, Denisova AO, Andronova VL, Kayushin AL, Konstantinova ID, Kotovskaya SK, Galegov GA, Charushin VN, Miroshnikov AI.. (2017) New modified 2-aminobenzimidazole nucleosides: Synthesis and evaluation of their activity against herpes simplex virus type 1., 27 (11): [PMID:28408228] [10.1016/j.bmcl.2017.03.100] |
| 124. Morgan RE, van Staden CJ, Chen Y, Kalyanaraman N, Kalanzi J, Dunn RT, Afshari CA, Hamadeh HK.. (2013) A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development., 136 (1): [PMID:23956101] [10.1093/toxsci/kft176] |
| 125. Chen M, Suzuki A, Thakkar S, Yu K, Hu C, Tong W.. (2016) DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans., 21 (4): [PMID:26948801] [10.1016/j.drudis.2016.02.015] |
| 126. Luo M, Groaz E, Andrei G, Snoeck R, Kalkeri R, Ptak RG, Hartman T, Buckheit RW, Schols D, De Jonghe S, Herdewijn P.. (2017) Expanding the Antiviral Spectrum of 3-Fluoro-2-(phosphonomethoxy)propyl Acyclic Nucleoside Phosphonates: Diamyl Aspartate Amidate Prodrugs., 60 (14): [PMID:28682067] [10.1021/acs.jmedchem.7b00416] |
| 127. Krečmerová M, Dračínský M, Snoeck R, Balzarini J, Pomeisl K, Andrei G.. (2017) New prodrugs of two pyrimidine acyclic nucleoside phosphonates: Synthesis and antiviral activity., 25 (17): [PMID:28757102] [10.1016/j.bmc.2017.06.046] |
| 128. Pileggi E, Serpi M, Andrei G, Schols D, Snoeck R, Pertusati F.. (2018) Expedient synthesis and biological evaluation of alkenyl acyclic nucleoside phosphonate prodrugs., 26 (12): [PMID:29880251] [10.1016/j.bmc.2018.05.034] |
| 129. Bessières M, Hervin V, Roy V, Chartier A, Snoeck R, Andrei G, Lohier JF, Agrofoglio LA.. (2018) Highly convergent synthesis and antiviral activity of (E)-but-2-enyl nucleoside phosphonoamidates., 146 [PMID:29407990] [10.1016/j.ejmech.2018.01.086] |
| 130. Wang M, Srivastava P, Liu C, Snoeck R, Andrei G, De Jonghe S, Herdewijn P.. (2018) Synthesis and antiviral evaluation of cyclopentyl nucleoside phosphonates., 150 [PMID:29550734] [10.1016/j.ejmech.2018.03.008] |
| 131. Plebanek E, Lescrinier E, Andrei G, Snoeck R, Herdewijn P, De Jonghe S.. (2018) Emimycin and its nucleoside derivatives: Synthesis and antiviral activity., 144 [PMID:29268134] [10.1016/j.ejmech.2017.12.018] |
| 132. Luo M, Groaz E, De Jonghe S, Snoeck R, Andrei G, Herdewijn P.. (2018) Amidate Prodrugs of Cyclic 9-(S)-[3-Hydroxy-2-(phosphonomethoxy)propyl]adenine with Potent Anti-Herpesvirus Activity., 9 (4): [PMID:29670705] [10.1021/acsmedchemlett.8b00079] |
| 133. Sokolova AS, Yarovaya OI, Bormotov NI, Shishkina LN, Salakhutdinov NF.. (2018) Synthesis and antiviral activity of camphor-based 1,3-thiazolidin-4-one and thiazole derivatives as Orthopoxvirus-reproduction inhibitors., 9 (10): [PMID:30429979] [10.1039/C8MD00347E] |
| 134. Karypidou K, Ribone SR, Quevedo MA, Persoons L, Pannecouque C, Helsen C, Claessens F, Dehaen W.. (2018) Synthesis, biological evaluation and molecular modeling of a novel series of fused 1,2,3-triazoles as potential anti-coronavirus agents., 28 (21): [PMID:30286952] [10.1016/j.bmcl.2018.09.019] |
| 135. Hulpia F, Noppen S, Schols D, Andrei G, Snoeck R, Liekens S, Vervaeke P, Van Calenbergh S.. (2018) Synthesis of a 3'-C-ethynyl-β-d-ribofuranose purine nucleoside library: Discovery of C7-deazapurine analogs as potent antiproliferative nucleosides., 157 [PMID:30098481] [10.1016/j.ejmech.2018.07.062] |
| 136. Unpublished dataset, |
| 137. Bernhard Ellinger, Denisa Bojkova, Andrea Zaliani, Jindrich Cinatl, Carsten Claussen, Sandra Westhaus, Jeanette Reinshagen, Maria Kuzikov, Markus Wolf, Gerd Geisslinger, Philip Gribbon, Sandra Ciesek. (2020) Identification of inhibitors of SARS-CoV-2 in-vitro cellular toxicity in human (Caco-2) cells using a large scale drug repurposing collection, [10.21203/rs.3.rs-23951/v1] |
| 138. Katie Heiser, Peter F. McLean, Chadwick T. Davis, Ben Fogelson, Hannah B. Gordon, Pamela Jacobson, Brett Hurst, Ben Miller, Ronald W. Alfa, Berton A. Earnshaw, Mason L. Victors, Yolanda T. Chong, Imran S. Haque, Adeline S. Low, Christopher C. Gibson. (2020) Identification of potential treatments for COVID-19 through artificial intelligence-enabled phenomic analysis of human cells infected with SARS-CoV-2, [10.1101/2020.04.21.054387] |
| 139. Mazzotta S, Marrugal-Lorenzo JA, Vega-Holm M, Serna-Gallego A, Álvarez-Vidal J, Berastegui-Cabrera J, Pérez Del Palacio J, Díaz C, Aiello F, Pachón J, Iglesias-Guerra F, Vega-Pérez JM, Sánchez-Céspedes J.. (2020) Optimization of piperazine-derived ureas privileged structures for effective antiadenovirus agents., 185 [PMID:31711794] [10.1016/j.ejmech.2019.111840] |
| 140. Kovaleva KS, Zubkov FI, Bormotov NI, Novikov RA, Dorovatovskii PV, Khrustalev VN, Gatilov YV, Zarubaev VV, Yarovaya OI, Shishkina LN, Salakhutdinov NF.. (2018) Synthesis of d-(+)-camphor-based N-acylhydrazones and their antiviral activity., 9 (12): [PMID:30746065] [10.1039/C8MD00442K] |
| 141. Mohammed AF, Andrei G, Hayallah AM, Abdel-Moty SG, Snoeck R, Simons C.. (2019) Synthesis and anti-HSV activity of tricyclic penciclovir and hydroxybutylguanine derivatives., 27 (6): [PMID:30738653] [10.1016/j.bmc.2019.02.005] |
| 142. Macan AM, Harej A, Cazin I, Klobučar M, Stepanić V, Pavelić K, Pavelić SK, Schols D, Snoeck R, Andrei G, Raić-Malić S.. (2019) Antitumor and antiviral activities of 4-substituted 1,2,3-triazolyl-2,3-dibenzyl-L-ascorbic acid derivatives., 184 [PMID:31586832] [10.1016/j.ejmech.2019.111739] |
| 143. Maria Kuzikov, Elisa Costanzi, Jeanette Reinshagen, Francesca Esposito, Laura Vangeel, Markus Wolf, Bernhard Ellinger, Carsten Claussen, Gerd Geisslinger, Angela Corona, Daniela Iaconis, Carmine Talarico, Candida Manelfi, Rolando Cannalire, Giulia Rossetti, Jonas Gossen, Simone Albani, Francesco Musiani, Katja Herzog, Yang Ye, Barbara Giabbai, Nicola Demitri, Dirk Jochmans, Steven De Jonghe, Jasper Rymenants, Vincenzo Summa, Enzo Tramontano, Andrea R. Beccari, Pieter Leyssen, Paola Storici, Johan Neyts, Philip Gribbon, and Andrea Zaliani. (2020) Identification of inhibitors of SARS-Cov2 M-Pro enzymatic activity using a small molecule repurposing screen, [10.6019/CHEMBL4495564] |
| 144. Maria Kuzikov, Elisa Costanzi, Jeanette Reinshagen, Francesca Esposito, Laura Vangeel, Markus Wolf, Bernhard Ellinger, Carsten Claussen, Gerd Geisslinger, Angela Corona, Daniela Iaconis, Carmine Talarico, Candida Manelfi, Rolando Cannalire, Giulia Rossetti, Jonas Gossen, Simone Albani, Francesco Musiani, Katja Herzog, Yang Ye, Barbara Giabbai, Nicola Demitri, Dirk Jochmans, Steven De Jonghe, Jasper Rymenants, Vincenzo Summa, Enzo Tramontano, Andrea R. Beccari, Pieter Leyssen, Paola Storici, Johan Neyts, Philip Gribbon, and Andrea Zaliani. (2020) Identification of inhibitors of SARS-Cov2 M-Pro enzymatic activity using a small molecule repurposing screen, [10.6019/CHEMBL4495564] |
| 145. Andrea Zaliani, Laura Vangeel, Jeanette Reinshagen, Daniela Iaconis, Maria Kuzikov, Oliver Keminer, Markus Wolf, Bernhard Ellinger, Francesca Esposito, Angela Corona, Enzo Tramontano, Candida Manelfi, Katja Herzog, Dirk Jochmans, Steven De Jonghe, Winston Chiu, Thibault Francken, Joost Schepers, Caroline Collard, Kayvan Abbasi, Carsten Claussen , Vincenzo Summa, Andrea R. Beccari, Johan Neyts, Philip Gribbon and Pieter Leyssen. (2020) Cytopathic SARS-Cov2 screening on VERO-E6 cells in a large repurposing effort, [10.6019/CHEMBL4495565] |
| 146. Andrea Zaliani, Laura Vangeel, Jeanette Reinshagen, Daniela Iaconis, Maria Kuzikov, Oliver Keminer, Markus Wolf, Bernhard Ellinger, Francesca Esposito, Angela Corona, Enzo Tramontano, Candida Manelfi, Katja Herzog, Dirk Jochmans, Steven De Jonghe, Winston Chiu, Thibault Francken, Joost Schepers, Caroline Collard, Kayvan Abbasi, Carsten Claussen , Vincenzo Summa, Andrea R. Beccari, Johan Neyts, Philip Gribbon and Pieter Leyssen. (2020) Cytopathic SARS-Cov2 screening on VERO-E6 cells in a large repurposing effort, [10.6019/CHEMBL4495565] |
| 147. Luo M, Groaz E, Snoeck R, Andrei G, Herdewijn P.. (2020) Amidate Prodrugs of O-2-Alkylated Pyrimidine Acyclic Nucleosides Display Potent Anti-Herpesvirus Activity., 11 (7): [PMID:32676147] [10.1021/acsmedchemlett.0c00090] |
| 148. Zheng Z,Groaz E,Snoeck R,De Jonghe S,Herdewijn P,Andrei G. (2021) Influence of 4'-Substitution on the Activity of Gemcitabine and Its ProTide Against VZV and SARS-CoV-2., 12 (1): [PMID:33479570] [10.1021/acsmedchemlett.0c00485] |
| 149. Suslov, Evgenii V., Mozhaytsev, Evgenii S., Korchagina, Dina V., Bormotov, Nikolay I., Yarovaya, Olga I., Volcho, Konstantin P., Serova, Olga A., Agafonov, Alexander P., Maksyutov, Rinat A., Shishkina, Larisa N., Salakhutdinov, Nariman F.. (2020) New chemical agents based on adamantane-monoterpene conjugates against orthopoxvirus infections, 11 (10): [PMID:33479623] [10.1039/d0md00108b] |
| 150. Beadle JR,Valiaeva N,Yang G,Yu JH,Broker TR,Aldern KA,Harden EA,Keith KA,Prichard MN,Hartman T,Buckheit RW,Chow LT,Hostetler KY. (2016) Synthesis and Antiviral Evaluation of Octadecyloxyethyl Benzyl 9-[(2-Phosphonomethoxy)ethyl]guanine (ODE-Bn-PMEG), a Potent Inhibitor of Transient HPV DNA Amplification., 59 (23.0): [PMID:27933957] [10.1021/acs.jmedchem.6b00659] |
| 151. Bernhard Ellinger, Justus Dick, Vanessa Lage-Rupprecht, Bruce Schultz, Andrea Zaliani, Marcin Namysl, Stephan Gebel, Ole Pless, Jeanette Reinshagen, Christian Ebeling, Alexander Esser, Marc Jacobs, Carsten Claussen, and Martin Hofmann-Apitius. (2021) HDAC6 screening dataset using tau-based substrate in an enzymatic assay yields selective inhibitors and activators, [10.6019/CHEMBL4808148] |
| 152. Pęcak P, Orzechowska B, Chrobak E, Boryczka S.. (2021) Novel betulin dicarboxylic acid ester derivatives as potent antiviral agents: Design, synthesis, biological evaluation, structure-activity relationship and in-silico study., 225 [PMID:34425312] [10.1016/j.ejmech.2021.113738] |
| 153. Kozlovskaya LI, Volok VP, Shtro AA, Nikolaeva YV, Chistov AA, Matyugina ES, Belyaev ES, Jegorov AV, Snoeck R, Korshun VA, Andrei G, Osolodkin DI, Ishmukhametov AA, Aralov AV.. (2021) Phenoxazine nucleoside derivatives with a multiple activity against RNA and DNA viruses., 220 [PMID:33894564] [10.1016/j.ejmech.2021.113467] |
| 154. De Fenza M, Esposito A, Talarico G, Andrei G, Snoeck R, D'Alonzo D, Guaragna A.. (2022) Synthesis and antiviral properties of biomimetic iminosugar-based nucleosides., 241 [PMID:35933787] [10.1016/j.ejmech.2022.114618] |
| 155. Nikitina PA, Basanova EI, Nikolaenkova EB, Os'kina IA, Serova OA, Bormotov NI, Shishkina LN, Perevalov VP, Tikhonov AY.. (2023) Synthesis of esters and amides of 2-aryl-1-hydroxy-4-methyl-1H-imidazole-5-carboxylic acids and study of their antiviral activity against orthopoxviruses., 79 [PMID:36414175] [10.1016/j.bmcl.2022.129080] |
| 156. Di Micco S, Rahimova R, Sala M, Scala MC, Vivenzio G, Musella S, Andrei G, Remans K, Mammri L, Snoeck R, Bifulco G, Di Matteo F, Vestuto V, Campiglia P, Márquez JA, Fasano A.. (2022) Rational design of the zonulin inhibitor AT1001 derivatives as potential anti SARS-CoV-2., 244 [PMID:36332548] [10.1016/j.ejmech.2022.114857] |
| 157. Sutherland JJ, Yonchev D, Fekete A, Urban L.. (2023) A preclinical secondary pharmacology resource illuminates target-adverse drug reaction associations of marketed drugs., 14 (1): [PMID:37468498] [10.1038/s41467-023-40064-9] |
| 158. European Medicines Agency, |
