Glutamyl-gamma-boronate analogue

ID: ALA87796

Chembl Id: CHEMBL87796

Cas Number: 334700-46-8

PubChem CID: 9793828

Max Phase: Preclinical

Molecular Formula: C4H10BNO4

Molecular Weight: 146.94

Molecule Type: Small molecule

Names and Identifiers

Canonical SMILES:  N[C@@H](CCB(O)O)C(=O)O

Standard InChI:  InChI=1S/C4H10BNO4/c6-3(4(7)8)1-2-5(9)10/h3,9-10H,1-2,6H2,(H,7,8)/t3-/m0/s1

Standard InChI Key:  KSYFGBKMRXVJSG-VKHMYHEASA-N

Alternative Forms

1. Parent:

   

   ALA87796

   (S)-2-Amino-4-boronobutanoic acid

2. Alternative Forms:

   

   ALA87796

   ---

Molecule Features

Natural Product: No

Oral: No

Chemical Probe: No

Parenteral: No

Molecule Type: Small molecule

Topical: No

First In Class: No

Black Box: No

Chirality: No

Availability: No

Prodrug: No

Calculated Properties

Molecular Weight: 146.94

Molecular Weight (Monoisotopic): 147.0703

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References

1. Decicco CP, Nelson DJ, Luo Y, Shen L, Horiuchi KY, Amsler KM, Foster LA, Spitz SM, Merrill JJ, Sizemore CF, Rogers KC, Copeland RA, Harpel MR..  (2001)  Glutamyl-gamma-boronate inhibitors of bacterial Glu-tRNA(Gln) amidotransferase.,  11  (18): [PMID:11549469] [10.1016/s0960-894x(01)00499-1]

Source

Source(1):

• Scientific Literature