| 1. Manchand PS, Cerruti RL, Martin JA, Hill CH, Merrett JH, Keech E, Belshe RB, Connell EV, Sim IS.. (1990) Synthesis and antiviral activity of metabolites of rimantadine., 33 (7): [PMID:2362279] [10.1021/jm00169a029] |
| 2. Kolocouris N, Kolocouris A, Foscolos GB, Fytas G, Neyts J, Padalko E, Balzarini J, Snoeck R, Andrei G, De Clercq E.. (1996) Synthesis and antiviral activity evaluation of some new aminoadamantane derivatives. 2., 39 (17): [PMID:8765514] [10.1021/jm950891z] |
| 3. Kolocouris A, Tataridis D, Fytas G, Mavromoustakos T, Foscolos GB, Kolocouris N, De Clercq E.. (1999) Synthesis of 2-(2-adamantyl)piperidines and structure anti-influenza virus A activity relationship study using a combination of NMR spectroscopy and molecular modeling., 9 (24): [PMID:10617092] [10.1016/s0960-894x(99)00631-9] |
| 4. Kolocouris N, Zoidis G, Foscolos GB, Fytas G, Prathalingham SR, Kelly JM, Naesens L, De Clercq E.. (2007) Design and synthesis of bioactive adamantane spiro heterocycles., 17 (15): [PMID:17588747] [10.1016/j.bmcl.2007.04.108] |
| 5. Gawin R, De Clercq E, Naesens L, Koszytkowska-Stawińska M.. (2008) Synthesis and antiviral evaluation of acyclic azanucleosides developed from sulfanilamide as a lead structure., 16 (18): [PMID:18778942] [10.1016/j.bmc.2008.08.041] |
| 6. Camps P, Duque MD, Vázquez S, Naesens L, De Clercq E, Sureda FX, López-Querol M, Camins A, Pallàs M, Prathalingam SR, Kelly JM, Romero V, Ivorra D, Cortés D.. (2008) Synthesis and pharmacological evaluation of several ring-contracted amantadine analogs., 16 (23): [PMID:18954995] [10.1016/j.bmc.2008.10.028] |
| 7. Zoidis G, Kolocouris N, Naesens L, De Clercq E.. (2009) Design and synthesis of 1,2-annulated adamantane piperidines with anti-influenza virus activity., 17 (4): [PMID:19195900] [10.1016/j.bmc.2009.01.009] |
| 8. Piscitelli F, Coluccia A, Brancale A, La Regina G, Sansone A, Giordano C, Balzarini J, Maga G, Zanoli S, Samuele A, Cirilli R, La Torre F, Lavecchia A, Novellino E, Silvestri R.. (2009) Indolylarylsulfones bearing natural and unnatural amino acids. Discovery of potent inhibitors of HIV-1 non-nucleoside wild type and resistant mutant strains reverse transcriptase and coxsackie B4 virus., 52 (7): [PMID:19281225] [10.1021/jm801470b] |
| 9. Duque MD, Camps P, Profire L, Montaner S, Vázquez S, Sureda FX, Mallol J, López-Querol M, Naesens L, De Clercq E, Prathalingam SR, Kelly JM.. (2009) Synthesis and pharmacological evaluation of (2-oxaadamant-1-yl)amines., 17 (8): [PMID:19251424] [10.1016/j.bmc.2009.02.007] |
| 10. Pintér G, Batta G, Kéki S, Mándi A, Komáromi I, Takács-Novák K, Sztaricskai F, Röth E, Ostorházi E, Rozgonyi F, Naesens L, Herczegh P.. (2009) Diazo transfer-click reaction route to new, lipophilic teicoplanin and ristocetin aglycon derivatives with high antibacterial and anti-influenza virus activity: an aggregation and receptor binding study., 52 (19): [PMID:19791806] [10.1021/jm900950d] |
| 11. Duque MD, Camps P, Torres E, Valverde E, Sureda FX, López-Querol M, Camins A, Prathalingam SR, Kelly JM, Vázquez S.. (2010) New oxapolycyclic cage amines with NMDA receptor antagonist and trypanocidal activities., 18 (1): [PMID:19954985] [10.1016/j.bmc.2009.11.017] |
| 12. Zarubaev VV, Golod EL, Anfimov PM, Shtro AA, Saraev VV, Gavrilov AS, Logvinov AV, Kiselev OI.. (2010) Synthesis and anti-viral activity of azolo-adamantanes against influenza A virus., 18 (2): [PMID:20006516] [10.1016/j.bmc.2009.11.047] |
| 13. Pintér G, Bereczki I, Batta G, Otvös R, Sztaricskai F, Roth E, Ostorházi E, Rozgonyi F, Naesens L, Szarvas M, Boda Z, Herczegh P.. (2010) Click reaction synthesis of carbohydrate derivatives from ristocetin aglycon with antibacterial and antiviral activity., 20 (9): [PMID:20381348] [10.1016/j.bmcl.2010.03.080] |
| 14. Eleftheratos S, Spearpoint P, Ortore G, Kolocouris A, Martinelli A, Martin S, Hay A.. (2010) Interaction of aminoadamantane derivatives with the influenza A virus M2 channel-docking using a pore blocking model., 20 (14): [PMID:20570509] [10.1016/j.bmcl.2010.05.049] |
| 15. Mahmoudi N, Garcia-Domenech R, Galvez J, Farhati K, Franetich JF, Sauerwein R, Hannoun L, Derouin F, Danis M, Mazier D.. (2008) New active drugs against liver stages of Plasmodium predicted by molecular topology., 52 (4): [PMID:18212104] [10.1128/aac.01043-07] |
| 16. Karpenko I, Deev S, Kiselev O, Charushin V, Rusinov V, Ulomsky E, Deeva E, Yanvarev D, Ivanov A, Smirnova O, Kochetkov S, Chupakhin O, Kukhanova M.. (2010) Antiviral properties, metabolism, and pharmacokinetics of a novel azolo-1,2,4-triazine-derived inhibitor of influenza A and B virus replication., 54 (5): [PMID:20194696] [10.1128/aac.01186-09] |
| 17. Zoidis G, Kolocouris N, Kelly JM, Prathalingam SR, Naesens L, De Clercq E.. (2010) Design and synthesis of bioactive adamantanaminoalcohols and adamantanamines., 45 (11): [PMID:20805012] [10.1016/j.ejmech.2010.08.009] |
| 18. Kumar KS, Ganguly S, Veerasamy R, De Clercq E.. (2010) Synthesis, antiviral activity and cytotoxicity evaluation of Schiff bases of some 2-phenyl quinazoline-4(3)H-ones., 45 (11): [PMID:20724039] [10.1016/j.ejmech.2010.07.058] |
| 19. Yadav S, Kumar P, De Clercq E, Balzarini J, Pannecouque C, Dewan SK, Narasimhan B.. (2010) 4-[1-(Substituted aryl/alkyl carbonyl)-benzoimidazol-2-yl]-benzenesulfonic acids: synthesis, antimicrobial activity, QSAR studies, and antiviral evaluation., 45 (12): [PMID:20971531] [10.1016/j.ejmech.2010.09.065] |
| 20. Matthews EJ, Kruhlak NL, Weaver JL, Benz RD, Contrera JF.. (2004) Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling., 1 (4): [PMID:16472241] [10.2174/1570163043334794] |
| 21. Fytas C, Zoidis G, Tzoutzas N, Taylor MC, Fytas G, Kelly JM.. (2011) Novel lipophilic acetohydroxamic acid derivatives based on conformationally constrained spiro carbocyclic 2,6-diketopiperazine scaffolds with potent trypanocidal activity., 54 (14): [PMID:21542562] [10.1021/jm200217m] |
| 22. PubChem BioAssay data set, |
| 23. Scott S. Auerbach, DrugMatrix¨ and ToxFX¨ Coordinator National Toxicology Program. DrugMatrix in vitro pharmacology data, |
| 24. Liu Z, Shi Q, Ding D, Kelly R, Fang H, Tong W.. (2011) Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps)., 7 (12): [PMID:22194678] [10.1371/journal.pcbi.1002310] |
| 25. Torres E, Duque MD, López-Querol M, Taylor MC, Naesens L, Ma C, Pinto LH, Sureda FX, Kelly JM, Vázquez S.. (2012) Synthesis of benzopolycyclic cage amines: NMDA receptor antagonist, trypanocidal and antiviral activities., 20 (2): [PMID:22178660] [10.1016/j.bmc.2011.11.050] |
| 26. Singh K, Kaur H, Chibale K, Balzarini J, Little S, Bharatam PV.. (2012) 2-Aminopyrimidine based 4-aminoquinoline anti-plasmodial agents. Synthesis, biological activity, structure-activity relationship and mode of action studies., 52 [PMID:22459876] [10.1016/j.ejmech.2012.03.007] |
| 27. Rodrigues T, Prudêncio M, Moreira R, Mota MM, Lopes F.. (2012) Targeting the liver stage of malaria parasites: a yet unmet goal., 55 (3): [PMID:22122518] [10.1021/jm201095h] |
| 28. Liu J, Obando D, Liao V, Lifa T, Codd R.. (2011) The many faces of the adamantyl group in drug design., 46 (6): [PMID:21354674] [10.1016/j.ejmech.2011.01.047] |
| 29. Torres E, Fernández R, Miquet S, Font-Bardia M, Vanderlinden E, Naesens L, Vázquez S.. (2012) Synthesis and Anti-influenza A Virus Activity of 2,2-Dialkylamantadines and Related Compounds., 3 (12): [PMID:24900429] [10.1021/ml300279b] |
| 30. Sokolov DN, Zarubaev VV, Shtro AA, Polovinka MP, Luzina OA, Komarova NI, Salakhutdinov NF, Kiselev OI.. (2012) Anti-viral activity of (-)- and (+)-usnic acids and their derivatives against influenza virus A(H1N1)2009., 22 (23): [PMID:23099095] [10.1016/j.bmcl.2012.09.084] |
| 31. Sipos A, Török Z, Rőth E, Kiss-Szikszai A, Batta G, Bereczki I, Fejes Z, Borbás A, Ostorházi E, Rozgonyi F, Naesens L, Herczegh P.. (2012) Synthesis of isoindole and benzoisoindole derivatives of teicoplanin pseudoaglycon with remarkable antibacterial and antiviral activities., 22 (23): [PMID:23099097] [10.1016/j.bmcl.2012.09.079] |
| 32. Göktaş F, Vanderlinden E, Naesens L, Cesur N, Cesur Z.. (2012) Microwave assisted synthesis and anti-influenza virus activity of 1-adamantyl substituted N-(1-thia-4-azaspiro[4.5]decan-4-yl)carboxamide derivatives., 20 (24): [PMID:23117173] [10.1016/j.bmc.2012.09.064] |
| 33. Karki SS, Kulkarni AA, Kumar S, Veliyath SK, De Clercq E, Balzarini J.. (2013) Synthesis and biological evaluation of 2-(5-substituted-1-((diethylamino)methyl)-2-oxoindolin-3-ylidene)-N-substituted-hydrazinecarbothioamides., 22 (4): [PMID:32214762] [10.1007/s00044-012-0184-x] |
| 34. Wittwer MB, Zur AA, Khuri N, Kido Y, Kosaka A, Zhang X, Morrissey KM, Sali A, Huang Y, Giacomini KM.. (2013) Discovery of potent, selective multidrug and toxin extrusion transporter 1 (MATE1, SLC47A1) inhibitors through prescription drug profiling and computational modeling., 56 (3): [PMID:23241029] [10.1021/jm301302s] |
| 35. Wang J, Ma C, Wang J, Jo H, Canturk B, Fiorin G, Pinto LH, Lamb RA, Klein ML, DeGrado WF.. (2013) Discovery of novel dual inhibitors of the wild-type and the most prevalent drug-resistant mutant, S31N, of the M2 proton channel from influenza A virus., 56 (7): [PMID:23437766] [10.1021/jm301538e] |
| 36. Korshin EE, Zakharova LG, Levin YA, Shulaeva MP, Pozdeev OK.. (2013) Anti-influenza active and low toxic N-phenyl-substituted β-amidoamidines structurally related to natural antibiotic amidinomycin., 23 (8): [PMID:23489622] [10.1016/j.bmcl.2013.02.053] |
| 37. Singh K, Kaur H, Chibale K, Balzarini J.. (2013) Synthesis of 4-aminoquinoline-pyrimidine hybrids as potent antimalarials and their mode of action studies., 66 [PMID:23811093] [10.1016/j.ejmech.2013.05.046] |
| 38. Singh K, Singh K, Balzarini J.. (2013) Regioselective synthesis of 6-substituted-2-amino-5-bromo-4(3H)-pyrimidinones and evaluation of their antiviral activity., 67 [PMID:23911856] [10.1016/j.ejmech.2013.06.036] |
| 39. Végner L, Peragovics Á, Tombor L, Jelinek B, Czobor P, Bender A, Simon Z, Málnási-Csizmadia A.. (2013) Experimental confirmation of new drug-target interactions predicted by Drug Profile Matching., 56 (21): [PMID:24088053] [10.1021/jm400813y] |
| 40. Rey-Carrizo M, Torres E, Ma C, Barniol-Xicota M, Wang J, Wu Y, Naesens L, DeGrado WF, Lamb RA, Pinto LH, Vázquez S.. (2013) 3-Azatetracyclo[5.2.1.1(5,8).0(1,5)]undecane derivatives: from wild-type inhibitors of the M2 ion channel of influenza A virus to derivatives with potent activity against the V27A mutant., 56 (22): [PMID:24237039] [10.1021/jm401340p] |
| 41. Biour M, Ben Salem C, Chazouillères O, Grangé JD, Serfaty L, Poupon R.. (2004) [Drug-induced liver injury; fourteenth updated edition of the bibliographic database of liver injuries and related drugs]., 28 (8-9): [PMID:15646539] [10.1016/s0399-8320(04)95062-2] |
| 42. PubChem BioAssay data set, |
| 43. Koperniku A, Papanastasiou I, Foscolos GB, Tsotinis A, Taylor MC, Kelly JM. (2013) Synthesis and trypanocidal action of new adamantane substituted imidazolines, 4 (5): [10.1039/C3MD00081H] |
| 44. Kolocouris A, Tzitzoglaki C, Johnson FB, Zell R, Wright AK, Cross TA, Tietjen I, Fedida D, Busath DD.. (2014) Aminoadamantanes with persistent in vitro efficacy against H1N1 (2009) influenza A., 57 (11): [PMID:24793875] [10.1021/jm500598u] |
| 45. Bereczki I, Kicsák M, Dobray L, Borbás A, Batta G, Kéki S, Nikodém ÉN, Ostorházi E, Rozgonyi F, Vanderlinden E, Naesens L, Herczegh P.. (2014) Semisynthetic teicoplanin derivatives as new influenza virus binding inhibitors: synthesis and antiviral studies., 24 (15): [PMID:24974341] [10.1016/j.bmcl.2014.06.018] |
| 46. Baltina LA, Zarubaev VV, Baltina LA, Orshanskaya IA, Fairushina AI, Kiselev OI, Yunusov MS.. (2015) Glycyrrhizic acid derivatives as influenza A/H1N1 virus inhibitors., 25 (8): [PMID:25801933] [10.1016/j.bmcl.2015.02.074] |
| 47. Bereczki I, Mándi A, Rőth E, Borbás A, Fizil Á, Komáromi I, Sipos A, Kurtán T, Batta G, Ostorházi E, Rozgonyi F, Vanderlinden E, Naesens L, Sztaricskai F, Herczegh P.. (2015) A few atoms make the difference: synthetic, CD, NMR and computational studies on antiviral and antibacterial activities of glycopeptide antibiotic aglycon derivatives., 94 [PMID:25752526] [10.1016/j.ejmech.2015.02.028] |
| 48. Rey-Carrizo M, Gazzarrini S, Llabrés S, Frigolé-Vivas M, Juárez-Jiménez J, Font-Bardia M, Naesens L, Moroni A, Luque FJ, Vázquez S.. (2015) New polycyclic dual inhibitors of the wild type and the V27A mutant M2 channel of the influenza A virus with unexpected binding mode., 96 [PMID:25899336] [10.1016/j.ejmech.2015.04.030] |
| 49. Geisman AN, Valuev-Elliston VT, Ozerov AA, Khandazhinskaya AL, Chizhov AO, Kochetkov SN, Pannecouque C, Naesens L, Seley-Radtke KL, Novikov MS.. (2016) 1,6-Bis[(benzyloxy)methyl]uracil derivatives-Novel antivirals with activity against HIV-1 and influenza H1N1 virus., 24 (11): [PMID:27112451] [10.1016/j.bmc.2016.04.010] |
| 50. WHO Anatomical Therapeutic Chemical Classification, |
| 51. Patrusheva OS, Zarubaev VV, Shtro AA, Orshanskaya YR, Boldyrev SA, Ilyina IV, Kurbakova SY, Korchagina DV, Volcho KP, Salakhutdinov NF.. (2016) Anti-influenza activity of monoterpene-derived substituted hexahydro-2H-chromenes., 24 (21): [PMID:27591012] [10.1016/j.bmc.2016.08.037] |
| 52. Khomenko TM, Zarubaev VV, Orshanskaya IR, Kadyrova RA, Sannikova VA, Korchagina DV, Volcho KP, Salakhutdinov NF.. (2017) Anti-influenza activity of monoterpene-containing substituted coumarins., 27 (13): [PMID:28501512] [10.1016/j.bmcl.2017.04.091] |
| 53. Chen M, Suzuki A, Thakkar S, Yu K, Hu C, Tong W.. (2016) DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans., 21 (4): [PMID:26948801] [10.1016/j.drudis.2016.02.015] |
| 54. Artyushin OI, Sharova EV, Vinogradova NM, Genkina GK, Moiseeva AA, Klemenkova ZS, Orshanskaya IR, Shtro AA, Kadyrova RA, Zarubaev VV, Yarovaya OI, Salakhutdinov NF, Brel VK.. (2017) Synthesis of camphecene derivatives using click chemistry methodology and study of their antiviral activity., 27 (10): [PMID:28366530] [10.1016/j.bmcl.2017.03.051] |
| 55. Barniol-Xicota M, Gazzarrini S, Torres E, Hu Y, Wang J, Naesens L, Moroni A, Vázquez S.. (2017) Slow but Steady Wins the Race: Dissimilarities among New Dual Inhibitors of the Wild-Type and the V27A Mutant M2 Channels of Influenza A Virus., 60 (9): [PMID:28418242] [10.1021/acs.jmedchem.6b01758] |
| 56. Tonelli M, Naesens L, Gazzarrini S, Santucci M, Cichero E, Tasso B, Moroni A, Costi MP, Loddo R.. (2017) Host dihydrofolate reductase (DHFR)-directed cycloguanil analogues endowed with activity against influenza virus and respiratory syncytial virus., 135 [PMID:28477572] [10.1016/j.ejmech.2017.04.070] |
| 57. Ilyina IV, Zarubaev VV, Lavrentieva IN, Shtro AA, Esaulkova IL, Korchagina DV, Borisevich SS, Volcho KP, Salakhutdinov NF.. (2018) Highly potent activity of isopulegol-derived substituted octahydro-2H-chromen-4-ols against influenza A and B viruses., 28 (11): [PMID:29716780] [10.1016/j.bmcl.2018.04.057] |
| 58. Pileggi E, Serpi M, Andrei G, Schols D, Snoeck R, Pertusati F.. (2018) Expedient synthesis and biological evaluation of alkenyl acyclic nucleoside phosphonate prodrugs., 26 (12): [PMID:29880251] [10.1016/j.bmc.2018.05.034] |
| 59. Francesconi V, Giovannini L, Santucci M, Cichero E, Costi MP, Naesens L, Giordanetto F, Tonelli M.. (2018) Synthesis, biological evaluation and molecular modeling of novel azaspiro dihydrotriazines as influenza virus inhibitors targeting the host factor dihydrofolate reductase (DHFR)., 155 [PMID:29886325] [10.1016/j.ejmech.2018.05.059] |
| 60. Drakopoulos A, Tzitzoglaki C, McGuire K, Hoffmann A, Konstantinidi A, Kolokouris D, Ma C, Freudenberger K, Hutterer J, Gauglitz G, Wang J, Schmidtke M, Busath DD, Kolocouris A.. (2018) Unraveling the Binding, Proton Blockage, and Inhibition of Influenza M2 WT and S31N by Rimantadine Variants., 9 (3): [PMID:29541360] [10.1021/acsmedchemlett.7b00458] |
| 61. Sokolova AS, Yarovaya OI, Semenova MD, Shtro AA, Orshanskaya IR, Zarubaev VV, Salakhutdinov NF.. (2017) Synthesis and in vitro study of novel borneol derivatives as potent inhibitors of the influenza A virus., 8 (5): [PMID:30108810] [10.1039/C6MD00657D] |
| 62. Szűcs Z, Kelemen V, Le Thai S, Csávás M, Rőth E, Batta G, Stevaert A, Vanderlinden E, Naesens L, Herczegh P, Borbás A.. (2018) Structure-activity relationship studies of lipophilic teicoplanin pseudoaglycon derivatives as new anti-influenza virus agents., 157 [PMID:30170320] [10.1016/j.ejmech.2018.08.058] |
| 63. Unpublished dataset, |
| 64. Katie Heiser, Peter F. McLean, Chadwick T. Davis, Ben Fogelson, Hannah B. Gordon, Pamela Jacobson, Brett Hurst, Ben Miller, Ronald W. Alfa, Berton A. Earnshaw, Mason L. Victors, Yolanda T. Chong, Imran S. Haque, Adeline S. Low, Christopher C. Gibson. (2020) Identification of potential treatments for COVID-19 through artificial intelligence-enabled phenomic analysis of human cells infected with SARS-CoV-2, [10.1101/2020.04.21.054387] |
| 65. Dar'in D, Zarubaev V, Galochkina A, Gureev M, Krasavin M.. (2019) Non-chelating p-phenylidene-linked bis-imidazoline analogs of known influenza virus endonuclease inhibitors: Synthesis and anti-influenza activity., 161 [PMID:30390440] [10.1016/j.ejmech.2018.10.063] |
| 66. Kovaleva KS, Zubkov FI, Bormotov NI, Novikov RA, Dorovatovskii PV, Khrustalev VN, Gatilov YV, Zarubaev VV, Yarovaya OI, Shishkina LN, Salakhutdinov NF.. (2018) Synthesis of d-(+)-camphor-based N-acylhydrazones and their antiviral activity., 9 (12): [PMID:30746065] [10.1039/C8MD00442K] |
| 67. Marvadi SK, Krishna VS, Sinegubova EO, Volobueva AS, Esaulkova YL, Muryleva AA, Tentler DG, Sriram D, Zarubaev VV, Kantevari S.. (2019) 5-Chloro-2-thiophenyl-1,2,3-triazolylmethyldihydroquinolines as dual inhibitors of Mycobacterium tuberculosis and influenza virus: Synthesis and evaluation., 29 (18): [PMID:31375291] [10.1016/j.bmcl.2019.07.040] |
| 68. Macan AM, Harej A, Cazin I, Klobučar M, Stepanić V, Pavelić K, Pavelić SK, Schols D, Snoeck R, Andrei G, Raić-Malić S.. (2019) Antitumor and antiviral activities of 4-substituted 1,2,3-triazolyl-2,3-dibenzyl-L-ascorbic acid derivatives., 184 [PMID:31586832] [10.1016/j.ejmech.2019.111739] |
| 69. Yarovaya OI, Sokolova AS, Mainagashev IY, Volobueva AS, Lantseva K, Borisevich SS, Shtro AA, Zarubaev VV, Salakhutdinov NF.. (2019) Synthesis and structure-activity relationships of novel camphecene analogues as anti-influenza agents., 29 (23): [PMID:31668423] [10.1016/j.bmcl.2019.126745] |
| 70. Narang R, Kumar R, Kalra S, Nayak SK, Khatik GL, Kumar GN, Sudhakar K, Singh SK.. (2019) Recent advancements in mechanistic studies and structure activity relationship of FoF1 ATP synthase inhibitor as antimicrobial agent., 182 [PMID:31493745] [10.1016/j.ejmech.2019.111644] |
| 71. Maria Kuzikov, Elisa Costanzi, Jeanette Reinshagen, Francesca Esposito, Laura Vangeel, Markus Wolf, Bernhard Ellinger, Carsten Claussen, Gerd Geisslinger, Angela Corona, Daniela Iaconis, Carmine Talarico, Candida Manelfi, Rolando Cannalire, Giulia Rossetti, Jonas Gossen, Simone Albani, Francesco Musiani, Katja Herzog, Yang Ye, Barbara Giabbai, Nicola Demitri, Dirk Jochmans, Steven De Jonghe, Jasper Rymenants, Vincenzo Summa, Enzo Tramontano, Andrea R. Beccari, Pieter Leyssen, Paola Storici, Johan Neyts, Philip Gribbon, and Andrea Zaliani. (2020) Identification of inhibitors of SARS-Cov2 M-Pro enzymatic activity using a small molecule repurposing screen, [10.6019/CHEMBL4495564] |
| 72. Andrea Zaliani, Laura Vangeel, Jeanette Reinshagen, Daniela Iaconis, Maria Kuzikov, Oliver Keminer, Markus Wolf, Bernhard Ellinger, Francesca Esposito, Angela Corona, Enzo Tramontano, Candida Manelfi, Katja Herzog, Dirk Jochmans, Steven De Jonghe, Winston Chiu, Thibault Francken, Joost Schepers, Caroline Collard, Kayvan Abbasi, Carsten Claussen , Vincenzo Summa, Andrea R. Beccari, Johan Neyts, Philip Gribbon and Pieter Leyssen. (2020) Cytopathic SARS-Cov2 screening on VERO-E6 cells in a large repurposing effort, [10.6019/CHEMBL4495565] |
| 73. Ulomskiy EN, Ivanova AV, Gorbunov EB, Esaulkova IL, Slita AV, Sinegubova EO, Voinkov EK, Drokin RA, Butorin II, Gazizullina ER, Gerasimova EL, Zarubaev VV, Rusinov VL.. (2020) Synthesis and biological evaluation of 6-nitro-1,2,4-triazoloazines containing polyphenol fragments possessing antioxidant and antiviral activity., 30 (13): [PMID:32360104] [10.1016/j.bmcl.2020.127216] |
| 74. Ellen Van Damme. (2021) Screening of ~5500 FDA-approved drugs and clinical candidates for anti-SARS-CoV-2 activity, [10.6019/CHEMBL4651402] |
| 75. Ilyina IV,Patrusheva OS,Zarubaev VV,Misiurina MA,Slita AV,Esaulkova IL,Korchagina DV,Gatilov YV,Borisevich SS,Volcho KP,Salakhutdinov NF. (2021) Influenza antiviral activity of F- and OH-containing isopulegol-derived octahydro-2H-chromenes., 31 [PMID:33171219] [10.1016/j.bmcl.2020.127677] |
| 76. Khomenko TM,Zarubaev VV,Kireeva MV,Volobueva AS,Slita AV,Borisevich SS,Korchagina DV,Komarova NI,Volcho KP,Salakhutdinov NF. (2020) New type of anti-influenza agents based on benzo[d][1,3]dithiol core., 30 (24): [PMID:33129992] [10.1016/j.bmcl.2020.127653] |
| 77. Bernhard Ellinger, Justus Dick, Vanessa Lage-Rupprecht, Bruce Schultz, Andrea Zaliani, Marcin Namysl, Stephan Gebel, Ole Pless, Jeanette Reinshagen, Christian Ebeling, Alexander Esser, Marc Jacobs, Carsten Claussen, and Martin Hofmann-Apitius. (2021) HDAC6 screening dataset using tau-based substrate in an enzymatic assay yields selective inhibitors and activators, [10.6019/CHEMBL4808148] |
| 78. Chernyshov VV, Yarovaya OI, Esaulkova IL, Sinegubova E, Borisevich SS, Popadyuk II, Zarubaev VV, Salakhutdinov NF.. (2022) Novel O-acylated amidoximes and substituted 1,2,4-oxadiazoles synthesised from (+)-ketopinic acid possessing potent virus-inhibiting activity against phylogenetically distinct influenza A viruses., 55 [PMID:34808389] [10.1016/j.bmcl.2021.128465] |
| 79. Beč A, Racané L, Žonja L, Persoons L, Daelemans D, Starčević K, Vianello R, Hranjec M.. (2023) Biological evaluation of novel amidino substituted coumarin-benzazole hybrids as promising therapeutic agents., 14 (5): [PMID:37252100] [10.1039/d3md00055a] |
| 80. Drakopoulos A, Tzitzoglaki C, Ma C, Freudenberger K, Hoffmann A, Hu Y, Gauglitz G, Schmidtke M, Wang J, Kolocouris A.. (2017) Affinity of Rimantadine Enantiomers against Influenza A/M2 Protein Revisited., 8 (2): [PMID:28217261] [10.1021/acsmedchemlett.6b00311] |
| 81. Suslov E, Zarubaev VV, Slita AV, Ponomarev K, Korchagina D, Ayine-Tora DM, Reynisson J, Volcho K, Salakhutdinov N.. (2017) Anti-influenza activity of diazaadamantanes combined with monoterpene moieties., 27 (19): [PMID:28886889] [10.1016/j.bmcl.2017.08.062] |
| 82. Sutherland JJ, Yonchev D, Fekete A, Urban L.. (2023) A preclinical secondary pharmacology resource illuminates target-adverse drug reaction associations of marketed drugs., 14 (1): [PMID:37468498] [10.1038/s41467-023-40064-9] |
| 83. Zimmermann M, Zimmermann-Kogadeeva M, Wegmann R, Goodman AL.. (2019) Mapping human microbiome drug metabolism by gut bacteria and their genes., 570 (7762): [PMID:31158845] [10.1038/s41586-019-1291-3] |
