ID: ALA1945
Type: SINGLE PROTEIN
Synonyms: Mel-1A-R | Mel1a receptor | Melatonin receptor type 1A | MTNR1A
Organism: Homo sapiens
Species Group: Homo sapiens
Protein Target Classification: Membrane receptor / Family A G protein-coupled receptor / Small molecule receptor (family A GPCR) / Monoamine-derivative receptor (family A GPCR) / Melatonin receptor
ALA ID | Relationship | Pref Name | Target Type |
---|---|---|---|
ALA2094268 | SUBSET OF | Melatonin receptor | PROTEIN FAMILY |
Description | Relationship | Accession |
---|---|---|
Melatonin receptor type 1A | PROTEIN | P48039 |
Name | Specification and purity | Expression system | Protein label | Activity | View Details |
---|
Name:
Cyclopropanecarboxylic acid [4-(3-methoxy-phenylamino)-phenyl]-amide
Mol. Formula:
C17H18N2O2
M.W.:
282.34
Type:
Small molecule
AlogP:
3.79
Polar Surface Area:
50.36
HBA:
3
HBD:
2
#RO5 Violations:
0
#Rotatable Bonds:
5
Passes Ro3:
N
QED Weighted:
0.88
Name:
N-{4-[(3-Methoxy-phenyl)-methyl-amino]-phenyl}-butyramide
Mol. Formula:
C18H22N2O2
M.W.:
298.39
Type:
Small molecule
AlogP:
4.20
Polar Surface Area:
41.57
HBA:
3
HBD:
1
#RO5 Violations:
0
#Rotatable Bonds:
6
Passes Ro3:
N
QED Weighted:
0.87
Name:
{4-[(3-Methoxy-phenyl)-methyl-amino]-phenyl}-carbamic acid ethyl ester
Mol. Formula:
C17H20N2O3
M.W.:
300.36
Type:
Small molecule
AlogP:
4.03
Polar Surface Area:
50.80
HBA:
4
HBD:
1
#RO5 Violations:
0
#Rotatable Bonds:
5
Passes Ro3:
N
QED Weighted:
0.91
Name:
Cyclopropanecarboxylic acid {4-[(3-methoxy-phenyl)-methyl-amino]-phenyl}-amide
Mol. Formula:
C18H20N2O2
M.W.:
296.37
Type:
Small molecule
AlogP:
3.81
Polar Surface Area:
41.57
HBA:
3
HBD:
1
#RO5 Violations:
0
#Rotatable Bonds:
5
Passes Ro3:
N
QED Weighted:
0.91
Name:
N-{4-[(3-Methoxy-phenyl)-methyl-amino]-phenyl}-isobutyramide
Mol. Formula:
C18H22N2O2
M.W.:
298.39
Type:
Small molecule
AlogP:
4.06
Polar Surface Area:
41.57
HBA:
3
HBD:
1
#RO5 Violations:
0
#Rotatable Bonds:
5
Passes Ro3:
N
QED Weighted:
0.90