ID: ALA2431
Type: SINGLE PROTEIN
Synonyms: 2.7.11.1 | AKT2 | PKB beta | Protein kinase Akt-2 | Protein kinase B beta | RAC-beta serine/threonine-protein kinase | RAC-PK-beta
Organism: Homo sapiens
Species Group: Homo sapiens
Protein Target Classification: Enzyme / Kinase / Protein Kinase / AGC protein kinase group / AGC protein kinase AKT family
ALA ID | Relationship | Pref Name | Target Type |
---|---|---|---|
ALA4106175 | SUBSET OF | Serine/threonine-protein kinase Rac alpha/beta | PROTEIN FAMILY |
ALA2111353 | SUBSET OF | Serine/threonine-protein kinase AKT | PROTEIN FAMILY |
ALA5169082 | SUBSET OF | CRBN/AKT2 | PROTEIN-PROTEIN INTERACTION |
Description | Relationship | Accession |
---|---|---|
RAC-beta serine/threonine-protein kinase | PROTEIN | P31751 |
Name | Specifications | Species reactivity | species | Application | View Details |
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Name:
(S)-1-(1H-indol-3-yl)-3-(5-(2-(pyridin-4-yl)vinyl)pyridin-3-yloxy)propan-2-amine
Mol. Formula:
C23H22N4O
M.W.:
370.46
Type:
Small molecule
AlogP:
4.08
Polar Surface Area:
76.82
HBA:
4
HBD:
2
#RO5 Violations:
0
#Rotatable Bonds:
7
Passes Ro3:
N
QED Weighted:
0.51
Name:
N-(2-(2-(4-chlorobenzyloxy)ethylamino)ethyl)isoquinoline-5-sulfonamide
Mol. Formula:
C20H22ClN3O3S
M.W.:
419.93
Type:
Small molecule
AlogP:
2.97
Polar Surface Area:
80.32
HBA:
5
HBD:
2
#RO5 Violations:
0
#Rotatable Bonds:
10
Passes Ro3:
N
QED Weighted:
0.49
Name:
(4-(9H-purin-6-yl)phenyl)(4-chlorophenyl)methanamine
Mol. Formula:
C18H14ClN5
M.W.:
335.80
Type:
Small molecule
AlogP:
3.72
Polar Surface Area:
80.48
HBA:
4
HBD:
2
#RO5 Violations:
0
#Rotatable Bonds:
3
Passes Ro3:
N
QED Weighted:
0.60
Name:
(4-(9H-purin-6-yl)phenyl)(4-chlorophenyl)-N-methylmethanamine
Mol. Formula:
C19H16ClN5
M.W.:
349.83
Type:
Small molecule
AlogP:
3.98
Polar Surface Area:
66.49
HBA:
4
HBD:
2
#RO5 Violations:
0
#Rotatable Bonds:
4
Passes Ro3:
N
QED Weighted:
0.58