ID: ALA2111353
Type: PROTEIN FAMILY
Synonyms: 2.7.11.1 | AKT2 | PKB beta | Protein kinase Akt-2 | Protein kinase B beta | RAC-beta serine/threonine-protein kinase | RAC-PK-beta
Organism: Homo sapiens
Species Group: Homo sapiens
Protein Target Classification: Enzyme / Kinase / Protein Kinase / AGC protein kinase group / AGC protein kinase AKT family
ALA ID | Relationship | Pref Name | Target Type |
---|---|---|---|
ALA4106175 | SUPERSET OF | Serine/threonine-protein kinase Rac alpha/beta | PROTEIN FAMILY |
ALA3038463 | OVERLAPS WITH | AKT/p21CIP1 | PROTEIN COMPLEX |
ALA3885629 | OVERLAPS WITH | RAC-alpha serine/threonine-protein kinase/Ribosomal protein S6 kinase beta-1 | PROTEIN FAMILY |
ALA2431 | SUPERSET OF | Serine/threonine-protein kinase AKT2 | SINGLE PROTEIN |
ALA4816 | SUPERSET OF | Serine/threonine-protein kinase AKT3 | SINGLE PROTEIN |
ALA4523748 | OVERLAPS WITH | AKT1/PPP1CA | PROTEIN-PROTEIN INTERACTION |
ALA5291687 | OVERLAPS WITH | Cereblon/RAC-gamma serine/threonine-protein kinase | PROTEIN-PROTEIN INTERACTION |
ALA4282 | SUPERSET OF | Serine/threonine-protein kinase AKT | SINGLE PROTEIN |
ALA5169082 | OVERLAPS WITH | CRBN/AKT2 | PROTEIN-PROTEIN INTERACTION |
ALA5169081 | OVERLAPS WITH | CRBN/AKT1 | PROTEIN-PROTEIN INTERACTION |
Name:
N-((S)-1-amino-3-(2,4-dichlorophenyl)propan-2-yl)-5-(2-(methylamino)pyrimidin-4-yl)thiophene-2-carboxamide
Mol. Formula:
C19H19Cl2N5OS
M.W.:
436.37
Type:
Small molecule
AlogP:
3.85
Polar Surface Area:
92.93
HBA:
6
HBD:
3
#RO5 Violations:
0
#Rotatable Bonds:
7
Passes Ro3:
N
QED Weighted:
0.52
Name:
Carbonic acid 2-methoxy-3-octadecyloxy-propyl ester 2,3,4,6-tetrahydroxy-5-hydroxymethyl-cyclohexyl ester
Mol. Formula:
C30H58O10
M.W.:
578.78
Type:
Small molecule
AlogP:
3.87
Polar Surface Area:
155.14
HBA:
10
HBD:
5
#RO5 Violations:
1
#Rotatable Bonds:
24
Passes Ro3:
N
QED Weighted:
0.08
Name:
Phosphoric acid 2-methoxy-3-octadecyloxy-propyl ester 2,3,4,6-tetrahydroxy-5-hydroxymethyl-cyclohexyl ester
Mol. Formula:
C29H59O11P
M.W.:
614.75
Type:
Small molecule
AlogP:
3.85
Polar Surface Area:
175.37
HBA:
10
HBD:
6
#RO5 Violations:
2
#Rotatable Bonds:
26
Passes Ro3:
N
QED Weighted:
0.06
Name:
Carbonic acid 2-methoxy-3-octadecyloxy-propyl ester 2,3,4,6-tetrahydroxy-cyclohexyl ester
Mol. Formula:
C29H56O9
M.W.:
548.76
Type:
Small molecule
AlogP:
4.65
Polar Surface Area:
134.91
HBA:
9
HBD:
4
#RO5 Violations:
1
#Rotatable Bonds:
23
Passes Ro3:
N
QED Weighted:
0.11
Name:
Phosphoric acid (R)-2-hexadecanoyl-4-oxo-nonadecyl ester (1S,2S,3S)-2,3,4,6-tetrahydroxy-cyclohexyl ester
Mol. Formula:
C41H79O10P
M.W.:
763.05
Type:
Small molecule
AlogP:
9.44
Polar Surface Area:
170.82
HBA:
9
HBD:
5
#RO5 Violations:
2
#Rotatable Bonds:
36
Passes Ro3:
N
QED Weighted:
0.03
Name:
Phosphoric acid (R)-2-imidazol-1-yl-3-octadecyloxy-propyl ester (1S,2S,3S)-2,3,4,6-tetrahydroxy-5-hydroxymethyl-cyclohexyl ester
Mol. Formula:
C31H59N2O10P
M.W.:
650.79
Type:
Small molecule
AlogP:
4.27
Polar Surface Area:
183.96
HBA:
11
HBD:
6
#RO5 Violations:
3
#Rotatable Bonds:
26
Passes Ro3:
N
QED Weighted:
0.06
Name:
Phosphoric acid (R)-2-imidazol-1-yl-3-octadecyloxy-propyl ester (1S,2S,3S)-2,3,4,6-tetrahydroxy-cyclohexyl ester
Mol. Formula:
C30H57N2O9P
M.W.:
620.76
Type:
Small molecule
AlogP:
5.05
Polar Surface Area:
163.73
HBA:
10
HBD:
5
#RO5 Violations:
2
#Rotatable Bonds:
25
Passes Ro3:
N
QED Weighted:
0.07
Name:
Phosphoric acid (R)-2-methoxy-3-octadecyloxy-propyl ester (1S,2S,3S)-2,3,4,6-tetrahydroxy-5-hydroxymethyl-cyclohexyl ester
Mol. Formula:
C29H59O11P
M.W.:
614.75
Type:
Small molecule
AlogP:
3.85
Polar Surface Area:
175.37
HBA:
10
HBD:
6
#RO5 Violations:
2
#Rotatable Bonds:
26
Passes Ro3:
N
QED Weighted:
0.06
Name:
Carbonic acid (R)-2-imidazol-1-yl-3-octadecyloxy-propyl ester (1S,2S,3S)-2,3,4,6-tetrahydroxy-5-hydroxymethyl-cyclohexyl ester
Mol. Formula:
C32H58N2O9
M.W.:
614.82
Type:
Small molecule
AlogP:
4.29
Polar Surface Area:
163.73
HBA:
11
HBD:
5
#RO5 Violations:
2
#Rotatable Bonds:
24
Passes Ro3:
N
QED Weighted:
0.08