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Baculoviral IAP repeat-containing protein 2/Epidermal growth factor receptor

Name And Classification

ID:  ALA4802031

Type:  PROTEIN-PROTEIN INTERACTION

Synonyms:   2.7.10.1 | EGFR | Epidermal growth factor receptor | ERBB | ERBB1 | HER1 | Proto-oncogene c-ErbB-1 | Receptor tyrosine-protein kinase erbB-1

Organism:  Homo sapiens

Species Group:  Homo sapiens

Protein Target Classification:   Enzyme / Kinase / Protein Kinase / TK protein kinase group / Tyrosine protein kinase EGFR family

Target Relations

ALA IDRelationshipPref NameTarget Type

Target Components

DescriptionRelationshipAccession
Epidermal growth factor receptorPROTEINP00533
Baculoviral IAP repeat-containing protein 2PROTEINQ13490

Associated Active Ligands

  1. Tetrahydrouridine
    ALA4741002

    Name:
    (S)-N-(12-(4-(4-((8-(3-acrylamidophenyl)-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)-3-methoxyphenyl)piperazin-1-yl)-12-oxododecyl)-2-((2S,3R)-3-amino-2-hydroxy-4-phenylbutanamido)-4-methylpentanamide

    Mol. Formula:
    C56H74N10O7

    M.W.:
    999.27

    Type:
    Unknown

    AlogP:
    7.09

    Polar Surface Area:
    226.14

    HBA:
    13

    HBD:
    6

    #RO5 Violations:
    4

    #Rotatable Bonds:
    27

    Passes Ro3:
    N

    QED Weighted:
    0.02

    DETAILS