Click Here for 5% Off Your First Aladdin Purchase!
Call +1 (833) 552-7181 or Contact us Earn $25 in coupons on your first order with Aladdin!
Toggle Nav
My Cart
Search
Advanced Search
Menu
Sign In
྾
main product photo

Deferoxamine mesylate - ≥98%, high purity , Iron chelating agent, CAS No.138-14-7, Iron chelating agent

  • ≥98%
Item Number
D302525
Grouped product items
SKUSizeAvailabilityPrice Qty
D302525-5mg
5mg
In stock
$9.90
D302525-25mg
25mg
In stock
$19.90
D302525-100mg
100mg
In stock
$44.90
D302525-250mg
250mg
In stock
$89.90
D302525-500mg
500mg
In stock
$159.90
D302525-1g
1g
In stock
$279.90
D302525-5g
5g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$1,299.90
Add to Wish List Compare
Bulk Order  SDS  DATASHEET

Iron chelator

View related series
Akt Apoptosis

Basic Description

SynonymsDeferoxamine mesylate|138-14-7|Desferal|Desferrioxamine B mesylate|Desferrioxamine mesylate|Deferoxamine mesilate|Deferoxamine methanesulfonate|Deferoxamine B mesylate|Deferoxamine (mesylate)|Desferal mesylate|DESFERRIOXAMINE MESILATE|MFCD00058605|V9TKO7E
Specifications & Purity≥98%
Biochemical and Physiological MechanismsIron chelator. Blood-brain barrier permeable. Displays a number of biological actions such as immunomodulation, inhibition of inflammation and atherosclerosis, and reduction of neuronal death.
Storage TempStore at -20°C,Argon charged
Shipped InIce chest + Ice pads
Action TypeCHELATING AGENT
Mechanism of actionIron chelating agent
NoteWherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Associated Targets

CYP1A2 Tchem Cytochrome P450 1A2 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

CYP2D6 Tclin Cytochrome P450 2D6 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

CYP2C19 Tchem Cytochrome P450 2C19 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

CTRC Tchem Chymotrypsin-C 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

CYP3A4 Tclin Cytochrome P450 3A4 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

CBX1 Tbio Chromobox protein homolog 1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

CYP2C9 Tchem Cytochrome P450 2C9 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

GMNN Tbio Geminin 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

FTL Tbio Ferritin light chain 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

SLCO1B1 Tchem Solute carrier organic anion transporter family member 1B1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

SMN1 Tchem Survival motor neuron protein 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

SLCO1B3 Tchem Solute carrier organic anion transporter family member 1B3 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

PLK1 Tchem Serine/threonine-protein kinase PLK1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

LMNA Tbio Prelamin-A/C 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

GAA Tclin Lysosomal alpha-glucosidase 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

MDH1 Tchem Malate dehydrogenase, cytoplasmic 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ATAD5 Tbio ATPase family AAA domain-containing protein 5 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

GLS Tchem Glutaminase kidney isoform, mitochondrial 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

NFE2L2 Tchem Nuclear factor erythroid 2-related factor 2 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

KDM4E Tchem Lysine-specific demethylase 4E 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name N-[5-[[4-[5-[acetyl(hydroxy)amino]pentylamino]-4-oxobutanoyl]-hydroxyamino]pentyl]-N'-(5-aminopentyl)-N'-hydroxybutanediamide;methanesulfonic acid
INCHI InChI=1S/C25H48N6O8.CH4O3S/c1-21(32)29(37)18-9-3-6-16-27-22(33)12-14-25(36)31(39)20-10-4-7-17-28-23(34)11-13-24(35)30(38)19-8-2-5-15-26;1-5(2,3)4/h37-39H,2-20,26H2,1H3,(H,27,33)(H,28,34);1H3,(H,2,3,4)
InChi Key IDDIJAWJANBQLJ-UHFFFAOYSA-N
Canonical SMILES CC(=O)N(CCCCCNC(=O)CCC(=O)N(CCCCCNC(=O)CCC(=O)N(CCCCCN)O)O)O.CS(=O)(=O)O
Isomeric SMILES CC(=O)N(CCCCCNC(=O)CCC(=O)N(CCCCCNC(=O)CCC(=O)N(CCCCCN)O)O)O.CS(=O)(=O)O
PubChem CID 62881
Molecular Weight 656.79

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

47 results found

Lot NumberCertificate TypeDateItem
G2408414Certificate of AnalysisJun 29, 2024 D302525
G2408420Certificate of AnalysisJun 29, 2024 D302525
G2408426Certificate of AnalysisJun 29, 2024 D302525
G2408427Certificate of AnalysisJun 29, 2024 D302525
G2408429Certificate of AnalysisJun 29, 2024 D302525
G2408430Certificate of AnalysisJun 29, 2024 D302525
G2408431Certificate of AnalysisJun 29, 2024 D302525
C2416210Certificate of AnalysisMar 07, 2024 D302525
C2416212Certificate of AnalysisMar 07, 2024 D302525
C2416208Certificate of AnalysisMar 07, 2024 D302525
C2416207Certificate of AnalysisMar 07, 2024 D302525
C2416206Certificate of AnalysisMar 07, 2024 D302525
C2416204Certificate of AnalysisMar 07, 2024 D302525
C2416202Certificate of AnalysisMar 07, 2024 D302525
J2331321Certificate of AnalysisOct 21, 2023 D302525
J2331320Certificate of AnalysisOct 21, 2023 D302525
J2331322Certificate of AnalysisOct 21, 2023 D302525
J2331415Certificate of AnalysisOct 21, 2023 D302525
J2331416Certificate of AnalysisOct 21, 2023 D302525
J2331417Certificate of AnalysisOct 21, 2023 D302525
J2331418Certificate of AnalysisOct 21, 2023 D302525
A2415184Certificate of AnalysisOct 21, 2023 D302525
L2322155Certificate of AnalysisOct 21, 2023 D302525
G2307279Certificate of AnalysisJun 12, 2023 D302525
I2306034Certificate of AnalysisJun 12, 2023 D302525
G2307276Certificate of AnalysisJun 12, 2023 D302525
G2307275Certificate of AnalysisJun 12, 2023 D302525
G2307274Certificate of AnalysisJun 12, 2023 D302525
G2307273Certificate of AnalysisJun 12, 2023 D302525
G2307272Certificate of AnalysisJun 12, 2023 D302525
G2307271Certificate of AnalysisJun 12, 2023 D302525
G2307301Certificate of AnalysisJun 12, 2023 D302525
G2307270Certificate of AnalysisJun 12, 2023 D302525
G2307269Certificate of AnalysisJun 12, 2023 D302525
B23101012Certificate of AnalysisFeb 01, 2023 D302525
B2310542Certificate of AnalysisFeb 01, 2023 D302525
B2310543Certificate of AnalysisFeb 01, 2023 D302525
B2310544Certificate of AnalysisFeb 01, 2023 D302525
B2310545Certificate of AnalysisFeb 01, 2023 D302525
B2310546Certificate of AnalysisFeb 01, 2023 D302525
D2318960Certificate of AnalysisFeb 01, 2023 D302525
H2217345Certificate of AnalysisAug 01, 2022 D302525
H2217343Certificate of AnalysisAug 01, 2022 D302525
H2217342Certificate of AnalysisAug 01, 2022 D302525
H2217341Certificate of AnalysisAug 01, 2022 D302525
H2217340Certificate of AnalysisAug 01, 2022 D302525
H2217334Certificate of AnalysisAug 01, 2022 D302525

more

Chemical and Physical Properties

SensitivityMoisture sensitive、Air sensitive、Heat sensitive

Safety and Hazards(GHS)

Pictogram(s) GHS08,   GHS07
Signal Danger
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

H335:May cause respiratory irritation

H341:Suspected of causing genetic defects

H317:May cause an allergic skin reaction

H334:May cause allergy or asthma symptoms or breathing difficulties if inhaled

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P284:[In case of inadequate ventilation] Wear respiratory protection.

P281:Use personal protective equipment as required.

P271:Use only outdoors or in a well-ventilated area.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P403+P233:Store in a well-ventilated place. Keep container tightly closed.

P272:Contaminated work clothing should not be allowed out of the workplace.

P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention.

P362+P364:Take off contaminated clothing and wash it before reuse.

P203:Obtain, read and follow all safety instructions before use.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P318:if exposed or concerned, get medical advice.

P337+P317:If eye irritation persists: Get medical help.

P332+P317:If skin irritation occurs: Get medical help.

P319:Get medical help if you feel unwell.

P342+P316:If experiencing respiratory symptoms: Get emergence medical help immediately.

Related Documents

 SDS

 Specification Sheet

Alternative Products

  1. Deferoxamine mesylate (Ba 33112) - 10mM in DMSO, used for , CAS No. 138-14-7(DMSO), by Aladdin Scientific
    Deferoxamine mesylate (Ba 33112)

    Starting at $37.90

FAQs and Articles

FAQ
Frequently asked Questions about inhibitors and antagonists related products（FAQ）
Categories: Technical articles
Tags:
inhibitor FAQ Antagonists Frequently asked questions Instructions

References

1. Furukawa T et al..  (2017)  Chronic diazepam administration increases the expression of Lcn2 in the CNS..  Pharmacol Res Perspect,  5  (e00283).  [PMID:28596835]
2. Henning Y et al..  (2022)  Hypoxia aggravates ferroptosis in RPE cells by promoting the Fenton reaction..  Cell Death Dis,  13  (7): (662).  [PMID:35906211]
3. Rakshit J et al..  (2020)  Iron chelator Deferoxamine protects human neuroblastoma cell line SH-SY5Y from 6-Hydroxydopamine-induced apoptosis and autophagy dysfunction..  J Trace Elem Med Biol,  57  (126406).  [PMID:31570251]
4. Sias SR & Ingraham JL.  (1979)  Isolation and analysis of mutants of Pseudomonas aeruginosa unable to assimilate nitrate..  Arch Microbiol,  122  (3): (263-70).  [PMID:120727]
5. Tadokoro T et al..  (2020)  Mitochondria-dependent ferroptosis plays a pivotal role in doxorubicin cardiotoxicity..  JCI Insight,  5  (9):   [PMID:32376803]
6. Yao Q et al..  (2018)  Mesoporous silicate nanoparticles/3D nanofibrous scaffold-mediated dual-drug delivery for bone tissue engineering..  J Control Release,  279  (69-78).  [PMID:29649529]
7. You JH et al..  (2021)  PGRMC1-dependent lipophagy promotes ferroptosis in paclitaxel-tolerant persister cancer cells..  J Exp Clin Cancer Res,  40  (350).  [PMID:34749765]
8. Nishimura K et al..  (2018)  Type 3 iodothyronine deiodinase is expressed in human induced pluripotent stem cell derived cardiomyocytes..  Life Sci,  203  (276-281).  [PMID:29684447]
9. Fu C et al..  (2020)  The transcription factor ZFHX3 is crucial for the angiogenic function of hypoxia-inducible factor 1a in liver cancer cells..  J Biol Chem,  295  (20): (7060-7074).  [PMID:32277050]
10. Sugiyama A et al..  (2020)  xCT inhibitor sulfasalazine depletes paclitaxel-resistant tumor cells through ferroptosis in uterine serous carcinoma..  Oncol Lett,  20  (3): (2689-2700).  [PMID:32782585]

Solution Calculators

Privacy Policy Website Terms of Use Return policy Terms and Conditions of Sale Cookie Policy Sales Policy
Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.
Copyright © 2023-present Aladdin Scientific Corp . All rights reserved.