Call +1 (833) 552-7181 or Contact us Earn $25 in coupons on your first order with Aladdin!
Toggle Nav
My Cart
Search
Advanced Search
Menu
Sign In
྾
main product photo

Deltarasin - 96%, high purity , CAS No.1440898-61-2

  • ≥96%
Item Number
D125721
Grouped product items
SKUSizeAvailabilityPrice Qty
D125721-5mg
5mg
In stock
$147.90
D125721-10mg
10mg
In stock
$236.90
D125721-25mg
25mg
In stock
$533.90
D125721-50mg
50mg
In stock
$759.90
D125721-100mg
100mg
In stock
$1,214.90
Add to Wish List Compare
Bulk Order  SDS  DATASHEET

Basic Description

Specifications & Purity≥96%
Biochemical and Physiological Mechanisms

Description:
IC50 Value: 41±12 nM (binding to PDEδ in cell) [1]
Deltarasin is a novel and small molecule inhibitor which can inhibit the KRAS-PDEδ interaction and impairs oncogenic KRAS signalling.
Interfering with b

Storage TempStore at -20°C
Shipped InIce chest + Ice pads
Product Description

Product introduction

Deltarasin is an inhibitor of KRAS-PDEδ interaction with Kd of 38 nM for binding to purified PDEδ.

Associated Targets(Human)

PDE6D Tclin Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (4 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
PDE6D Tclin Phosphodiesterase 6D (241 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
A549 (127892 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HepG2 (196354 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PDE6D Tclin PDE6D/KRAS (21 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Hdac6 Histone deacetylase 6 (222 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PDE6D Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (1 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SARS-CoV-2 (38078 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Names and Identifiers

IUPAC Name 1-benzyl-2-[4-[(2S)-2-(2-phenylbenzimidazol-1-yl)-2-piperidin-4-ylethoxy]phenyl]benzimidazole
INCHI InChI=1S/C40H37N5O/c1-3-11-29(12-4-1)27-44-36-17-9-7-15-34(36)42-39(44)32-19-21-33(22-20-32)46-28-38(30-23-25-41-26-24-30)45-37-18-10-8-16-35(37)43-40(45)31-13-5-2-6-14-31/h1-22,30,38,41H,23-28H2/t38-/m1/s1
InChi Key LTZKEDSUXKTTTC-KXQOOQHDSA-N
Canonical SMILES C1CNCCC1C(COC2=CC=C(C=C2)C3=NC4=CC=CC=C4N3CC5=CC=CC=C5)N6C7=CC=CC=C7N=C6C8=CC=CC=C8
Isomeric SMILES C1CNCCC1[C@@H](COC2=CC=C(C=C2)C3=NC4=CC=CC=C4N3CC5=CC=CC=C5)N6C7=CC=CC=C7N=C6C8=CC=CC=C8
Alternate CAS 1440898-82-7
PubChem CID 73292904
Molecular Weight 603.75

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

10 results found

Lot NumberCertificate TypeDateItem
K2309373Certificate of AnalysisOct 10, 2023 D125721
K2309375Certificate of AnalysisOct 10, 2023 D125721
K2309376Certificate of AnalysisOct 10, 2023 D125721
K2309377Certificate of AnalysisOct 10, 2023 D125721
K2309378Certificate of AnalysisOct 10, 2023 D125721
K2309379Certificate of AnalysisOct 10, 2023 D125721
K2309380Certificate of AnalysisOct 10, 2023 D125721
K2309381Certificate of AnalysisOct 10, 2023 D125721
K2309409Certificate of AnalysisOct 10, 2023 D125721
K2309419Certificate of AnalysisOct 10, 2023 D125721

Chemical and Physical Properties

SolubilityDMSO

Related Documents

 SDS

 Specification Sheet

Alternative Products

  1. Deltarasin - 10mM in DMSO, used for , CAS No. 1440898-61-2, by Aladdin Scientific
    Deltarasin
    • 10mM in DMSO

    Starting at $634.90

Solution Calculators

Privacy Policy Website Terms of Use Return policy Terms and Conditions of Sale Cookie Policy Sales Policy
Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.
Copyright © 2023-present Aladdin Scientific Corp . All rights reserved.