K2202296Determine the necessary mass, volume, or concentration for preparing a solution.
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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Basic Description
| Synonyms | Norcantharidin | 5442-12-6 | Endothall anhydride | 29745-04-8 | Norcantharadine | Hexahydro-4,7-epoxyisobenzofuran-1,3-dione | 7-Oxabicyclo[2.2.1]heptane-2,3-dicarboxylic anhydride | 4,7-Epoxyisobenzofuran-1,3-dione, hexahydro- | (Rac)-Norcantharidin | 3,6-Endoxohexahydrop |
|---|---|
| Specifications & Purity | ≥98%(HPLC) |
| Shipped In | Normal |
Associated Targets(Human)
EHMT2 Tchem Histone-lysine N-methyltransferase EHMT2 (0 Activities)
GMNN Tbio Geminin (0 Activities)
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PPP5C Tbio Serine/threonine-protein phosphatase 5 (0 Activities)
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POLK Tbio DNA polymerase kappa (0 Activities)
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RAB9A Tbio Ras-related protein Rab-9A (0 Activities)
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PMP22 Tbio Peripheral myelin protein 22 (0 Activities)
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LMNA Tbio Prelamin-A/C (0 Activities)
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TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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ATAD5 Tbio ATPase family AAA domain-containing protein 5 (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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ARSA Tbio Arylsulfatase A (0 Activities)
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IMPA1 Tclin Inositol monophosphatase 1 (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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PPP1CA Tchem Serine/threonine-protein phosphatase PP1-alpha catalytic subunit (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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KDM4E Tchem Lysine-specific demethylase 4E (0 Activities)
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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PPP1CA Tchem Serine/threonine protein phosphatase PP1-alpha catalytic subunit (133 Activities)
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ARSA Tbio Cerebroside-sulfatase (655 Activities)
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A498 (42825 Activities)
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ACHN (49357 Activities)
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CAKI-1 (44928 Activities)
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CCRF-CEM (65223 Activities)
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COLO 205 (50209 Activities)
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DLD-1 (17511 Activities)
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DMS-273 (14108 Activities)
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HL-60 (67320 Activities)
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HT-29 (80576 Activities)
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K562 (73714 Activities)
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KM12 (47707 Activities)
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M14 (47487 Activities)
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MOLT-4 (49676 Activities)
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OVCAR-3 (48710 Activities)
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OVCAR-5 (45555 Activities)
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OVCAR-8 (47708 Activities)
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RPMI-8226 (44974 Activities)
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RXF 393 (41971 Activities)
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SF-295 (48000 Activities)
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SK-MEL-2 (46422 Activities)
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SK-MEL-28 (48833 Activities)
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SK-MEL-5 (47095 Activities)
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SK-OV-3 (52876 Activities)
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SN12C (47755 Activities)
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SNB-19 (46794 Activities)
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SNB-78 (14240 Activities)
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TK-10 (45540 Activities)
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U-251 (51189 Activities)
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UACC-257 (46019 Activities)
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UACC-62 (47335 Activities)
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UO-31 (46270 Activities)
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XF498 (12972 Activities)
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786-0 (47912 Activities)
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A549 (127892 Activities)
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EKVX (44102 Activities)
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NCI-H322M (45589 Activities)
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HCC 2998 (41480 Activities)
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HCT-116 (91556 Activities)
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HEK293 (82097 Activities)
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HOP-18 (11577 Activities)
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HOP-92 (41141 Activities)
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NCI-H460 (60772 Activities)
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SF-268 (49410 Activities)
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IGROV-1 (47897 Activities)
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HOP-62 (47048 Activities)
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LXFL 529 (14112 Activities)
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M19-MEL (15326 Activities)
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Malme-3M (44254 Activities)
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Associated Targets(non-human)
ampC Beta-lactamase AmpC (62480 Activities)
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Serine/threonine-protein phosphatase (23 Activities)
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Impa1 Inositol monophosphatase 1 (16203 Activities)
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Mechanisms of Action
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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Names and Identifiers
| IUPAC Name | 4,10-dioxatricyclo[5.2.1.02,6]decane-3,5-dione |
|---|---|
| INCHI | InChI=1S/C8H8O4/c9-7-5-3-1-2-4(11-3)6(5)8(10)12-7/h3-6H,1-2H2 |
| InChi Key | JAABVEXCGCXWRR-UHFFFAOYSA-N |
| Canonical SMILES | C1CC2C3C(C1O2)C(=O)OC3=O |
| Isomeric SMILES | C1CC2C3C(C1O2)C(=O)OC3=O |
| PubChem CID | 93004 |
| Molecular Weight | 168.15 |
Certificates
Certificate of Analysis(COA)
Enter Lot Number to search for COA:
Safety and Hazards(GHS)
| Pictogram(s) | GHS07 |
|---|---|
| Signal | Warning |
| Hazard Statements | H319:Causes serious eye irritation H302:Harmful if swallowed |
| Precautionary Statements | P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P330:Rinse mouth. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P317:IF SWALLOWED: Get medical help. P337+P317:If eye irritation persists: Get medical help. |