Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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D103698-20mg | 20mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $41.90 | |
D103698-50mg | 50mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $89.90 | |
D103698-100mg | 100mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $157.90 |
Synonyms | DEOXYCHOLIC ACID | 83-44-3 | deoxycholate | Desoxycholic acid | Cholerebic | Cholorebic | Choleic acid | Degalol | Deoxycholatic acid | Droxolan | Pyrochol | Septochol | Desoxycholsaeure | 7alpha-Deoxycholic acid | 3alpha,12alpha-Dihydroxy-5beta-cholanic acid | Cholic acid, deoxy- | Dih |
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Specifications & Purity | Moligand™, analytical standard, ≥99% |
Shipped In | Normal |
Grade | analytical standard, Moligand™ |
Action Type | AGONIST, ANTAGONIST |
Mechanism of action | Agonist of Farnesoid X receptor;Antagonist of FPR1;Agonist of GPBA receptor |
ALogP | 4.9 |
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IUPAC Name | (4R)-4-[(3R,5R,8R,9S,10S,12S,13R,14S,17R)-3,12-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid |
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INCHI | InChI=1S/C24H40O4/c1-14(4-9-22(27)28)18-7-8-19-17-6-5-15-12-16(25)10-11-23(15,2)20(17)13-21(26)24(18,19)3/h14-21,25-26H,4-13H2,1-3H3,(H,27,28)/t14-,15-,16-,17+,18-,19+,20+,21+,23+,24-/m1/s1 |
InChi Key | KXGVEGMKQFWNSR-LLQZFEROSA-N |
Canonical SMILES | CC(CCC(=O)O)C1CCC2C1(C(CC3C2CCC4C3(CCC(C4)O)C)O)C |
Isomeric SMILES | C[C@H](CCC(=O)O)[C@H]1CC[C@@H]2[C@@]1([C@H](C[C@H]3[C@H]2CC[C@H]4[C@@]3(CC[C@H](C4)O)C)O)C |
WGK Germany | 3 |
RTECS | FZ2100000 |
PubChem CID | 222528 |
Molecular Weight | 392.58 |
Beilstein | 3219882 |
Enter Lot Number to search for COA:
To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section
Lot Number | Certificate Type | Date | Item |
---|---|---|---|
F2218377 | Certificate of Analysis | Mar 20, 2024 | D103698 |
F2218378 | Certificate of Analysis | Mar 20, 2024 | D103698 |
E2323362 | Certificate of Analysis | Apr 23, 2023 | D103698 |
E2323562 | Certificate of Analysis | Apr 23, 2023 | D103698 |
E2323568 | Certificate of Analysis | Apr 23, 2023 | D103698 |
F2218379 | Certificate of Analysis | Jun 07, 2022 | D103698 |
Sensitivity | Moisture sensitive. |
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Pictogram(s) | GHS07 |
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Signal | Warning |
Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation H302:Harmful if swallowed |
Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P317:IF SWALLOWED: Get medical help. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell. |
WGK Germany | 3 |
RTECS | FZ2100000 |
1. Jinghua Li, Jia Lin, Xiaohua Chen, Meiqiu Feng, Ying Zheng. (2024) Silicon-induced optimization on phase structure and surface property of Pd/ZrO2 catalysts for enhanced methane combustion. APPLIED SURFACE SCIENCE, 643 (15): (158657). [PMID:21722858] |
2. Qiyi Feng, Jie Chen, Jinxing Huang, Xiaojie Li, Xinyi Liu, Chunxiu Xiao, Xiuli Zheng, Xuanming Chen, Jue Li, Zhongwei Gu, Kui Luo, Kai Xiao, Weimin Li. (2023) A redox-responsive nanosystem to suppress chemoresistant lung cancer through targeting STAT3. JOURNAL OF CONTROLLED RELEASE, 363 (29): (349). [PMID:37748583] |
3. Yan Ma, Yang Cao, Xiaocui Song, Weichen Xu, Zichen Luo, Jinjun Shan, Jingjie Zhou. (2023) Integration of semi-empirical MS/MS library with characteristic features for the annotation of novel amino acid-conjugated bile acids. ANALYST, 148 (21): (5380-5389). [PMID:37743718] |
4. Yawen Zhang, Yue Wu, Yuping Yan, Yijing Ma, Linglan Tu, Jingjing Shao, Xuanyu Tang, Lingfeng Chen, Guang Liang, Lina Yin. (2023) Dual-Targeted Nanoparticle-In-Microparticle System for Ulcerative Colitis Therapy. Advanced Healthcare Materials, (2301518). [PMID:37660262] |
5. Jie Zhou, Shengnan Li, Jin Zhang, Fusui Luo, Yiwen Sun, Min Guan, Huili Ma, Qian Liu. (2023) Ionic liquid combined with bile acid pathway for oral delivery of rhGH. JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY, 86 (104664). [PMID:] |
6. Jingmou Yu, Liangliang Wang, Yun Ling, Xin Xiao, Juntao Gong, Hongguang Jin, Jing Xu, Pu Chen, Xin Xie, Lei Zhang. (2023) Peptide-modified bioresponsive chondroitin sulfate micelles for targeted doxorubicin delivery in triple-negative breast cancer. COLLOIDS AND SURFACES B-BIOINTERFACES, 227 (113381). [PMID:37257299] |
7. Luo lixia, Ye ying, Wang hong, Liu zhe, Li Jiqian. (2023) Rapid detection of Ag+ in food using cholesteric chiral artificial receptor L5. MICROCHEMICAL JOURNAL, 190 (108633). [PMID:] |
8. Meirong Huo, Jiyuan Zhou, Honglan Wang, Yuzhao Zheng, Yuqing Tong, Jianping Zhou, Jiyong Liu, Tingjie Yin. (2022) A pHe sensitive nanodrug for collaborative penetration and inhibition of metastatic tumors. JOURNAL OF CONTROLLED RELEASE, 352 (893). [PMID:36370879] |
9. Jiating Zheng, Xiaoru Peng, Taifeng Zhu, Shuyao Huang, Chao Chen, Guosheng Chen, Shuqin Liu, Gangfeng Ouyang. (2022) Detection of bile acids in small volume human bile samples via an amino metal-organic framework composite based solid-phase microextraction probe. JOURNAL OF CHROMATOGRAPHY A, 1685 (463634). [PMID:36345074] |
10. Wei Xu, Yingying Kong, Tuo Zhang, Zhihua Gong, Wenjun Xiao. (2022) L-Theanine regulates lipid metabolism by modulating gut microbiota and bile acid metabolism. JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE, 103 (3): (1283-1293). [PMID:36087337] |
11. Zhenzhen Wang, Ziyu Zhai, Chunyu Chen, Xuejiao Tian, Zhen Xing, Panfei Xing, Yushun Yang, Junfeng Zhang, Chunming Wang, Lei Dong. (2022) Air pollution particles hijack peroxidasin to disrupt immunosurveillance and promote lung cancer. eLife, [PMID:35437145] |
12. Xiaoxu Cheng, Zifeng Pi, Zhong Zheng, Shu Liu, Fengrui Song, Zhiqiang Liu. (2022) Combined 16S rRNA gene sequencing and metabolomics to investigate the protective effects of Wu-tou decoction on rheumatoid arthritis in rats. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 1199 (123249). [PMID:35447521] |
13. Jing Li,Tingjie Yin,Lei Wang,Lifang Yin,Jianping Zhou,Meirong Huo. (2015-02-07) Biological evaluation of redox-sensitive micelles based on hyaluronic acid-deoxycholic acid conjugates for tumor-specific delivery of paclitaxel.. International journal of pharmaceutics, 483 ((1-2)): (38-48). [PMID:25655715] |
14. Zehong Xiang,Yanming Wang,Zhifang Ma,Zhirong Xin,Runhai Chen,Qiang Shi,Shing-Chung Wong,Jinghua Yin. (2019-06-22) Inhibition of Inflammation-Associated Thrombosis with ROS-Responsive Heparin-DOCA/PVAX Nanoparticles.. Macromolecular bioscience, 19 ((8)): (e1900112-e1900112). [PMID:31222912] |
1. Jinghua Li, Jia Lin, Xiaohua Chen, Meiqiu Feng, Ying Zheng. (2024) Silicon-induced optimization on phase structure and surface property of Pd/ZrO2 catalysts for enhanced methane combustion. APPLIED SURFACE SCIENCE, 643 (15): (158657). [PMID:21722858] |
2. Qiyi Feng, Jie Chen, Jinxing Huang, Xiaojie Li, Xinyi Liu, Chunxiu Xiao, Xiuli Zheng, Xuanming Chen, Jue Li, Zhongwei Gu, Kui Luo, Kai Xiao, Weimin Li. (2023) A redox-responsive nanosystem to suppress chemoresistant lung cancer through targeting STAT3. JOURNAL OF CONTROLLED RELEASE, 363 (29): (349). [PMID:37748583] |
3. Yan Ma, Yang Cao, Xiaocui Song, Weichen Xu, Zichen Luo, Jinjun Shan, Jingjie Zhou. (2023) Integration of semi-empirical MS/MS library with characteristic features for the annotation of novel amino acid-conjugated bile acids. ANALYST, 148 (21): (5380-5389). [PMID:37743718] |
4. Yawen Zhang, Yue Wu, Yuping Yan, Yijing Ma, Linglan Tu, Jingjing Shao, Xuanyu Tang, Lingfeng Chen, Guang Liang, Lina Yin. (2023) Dual-Targeted Nanoparticle-In-Microparticle System for Ulcerative Colitis Therapy. Advanced Healthcare Materials, (2301518). [PMID:37660262] |
5. Jie Zhou, Shengnan Li, Jin Zhang, Fusui Luo, Yiwen Sun, Min Guan, Huili Ma, Qian Liu. (2023) Ionic liquid combined with bile acid pathway for oral delivery of rhGH. JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY, 86 (104664). [PMID:] |
6. Jingmou Yu, Liangliang Wang, Yun Ling, Xin Xiao, Juntao Gong, Hongguang Jin, Jing Xu, Pu Chen, Xin Xie, Lei Zhang. (2023) Peptide-modified bioresponsive chondroitin sulfate micelles for targeted doxorubicin delivery in triple-negative breast cancer. COLLOIDS AND SURFACES B-BIOINTERFACES, 227 (113381). [PMID:37257299] |
7. Luo lixia, Ye ying, Wang hong, Liu zhe, Li Jiqian. (2023) Rapid detection of Ag+ in food using cholesteric chiral artificial receptor L5. MICROCHEMICAL JOURNAL, 190 (108633). [PMID:] |
8. Meirong Huo, Jiyuan Zhou, Honglan Wang, Yuzhao Zheng, Yuqing Tong, Jianping Zhou, Jiyong Liu, Tingjie Yin. (2022) A pHe sensitive nanodrug for collaborative penetration and inhibition of metastatic tumors. JOURNAL OF CONTROLLED RELEASE, 352 (893). [PMID:36370879] |
9. Jiating Zheng, Xiaoru Peng, Taifeng Zhu, Shuyao Huang, Chao Chen, Guosheng Chen, Shuqin Liu, Gangfeng Ouyang. (2022) Detection of bile acids in small volume human bile samples via an amino metal-organic framework composite based solid-phase microextraction probe. JOURNAL OF CHROMATOGRAPHY A, 1685 (463634). [PMID:36345074] |
10. Wei Xu, Yingying Kong, Tuo Zhang, Zhihua Gong, Wenjun Xiao. (2022) L-Theanine regulates lipid metabolism by modulating gut microbiota and bile acid metabolism. JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE, 103 (3): (1283-1293). [PMID:36087337] |
11. Zhenzhen Wang, Ziyu Zhai, Chunyu Chen, Xuejiao Tian, Zhen Xing, Panfei Xing, Yushun Yang, Junfeng Zhang, Chunming Wang, Lei Dong. (2022) Air pollution particles hijack peroxidasin to disrupt immunosurveillance and promote lung cancer. eLife, [PMID:35437145] |
12. Xiaoxu Cheng, Zifeng Pi, Zhong Zheng, Shu Liu, Fengrui Song, Zhiqiang Liu. (2022) Combined 16S rRNA gene sequencing and metabolomics to investigate the protective effects of Wu-tou decoction on rheumatoid arthritis in rats. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 1199 (123249). [PMID:35447521] |
13. Jing Li,Tingjie Yin,Lei Wang,Lifang Yin,Jianping Zhou,Meirong Huo. (2015-02-07) Biological evaluation of redox-sensitive micelles based on hyaluronic acid-deoxycholic acid conjugates for tumor-specific delivery of paclitaxel.. International journal of pharmaceutics, 483 ((1-2)): (38-48). [PMID:25655715] |
14. Zehong Xiang,Yanming Wang,Zhifang Ma,Zhirong Xin,Runhai Chen,Qiang Shi,Shing-Chung Wong,Jinghua Yin. (2019-06-22) Inhibition of Inflammation-Associated Thrombosis with ROS-Responsive Heparin-DOCA/PVAX Nanoparticles.. Macromolecular bioscience, 19 ((8)): (e1900112-e1900112). [PMID:31222912] |