Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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D129628-250mg | 250mg | In stock | $79.90 | |
D129628-1g | 1g | In stock | $226.90 | |
D129628-5g | 5g | In stock | $769.90 |
Steroid hormone used via intramuscular injections in the replacement therapy of the adrenocortical steroid
Synonyms | Cortexone acetate | Percotol | 11-Deoxycorticosterone acetate | Decosterone | Docaquosum | DOCA | DESOXYCORTICOSTERONE ACETATE | Decostrate | Descorterone | Decosteron | Desoxycortone acetate | Dorcostrin | Krinocorts | Sincortex | DOC-21-acetate | MLS000 |
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Specifications & Purity | ≥99% |
Biochemical and Physiological Mechanisms | Steroid hormone commonly used to induce hypertension in experimental animals. This form of hypertension is dependent on altered regulation of central pressor mechanisms including the brain renin-angiotensin system. |
Storage Temp | Store at 2-8°C |
Shipped In | Wet ice |
Action Type | AGONIST |
Mechanism of action | Mineralocorticoid receptor agonist |
Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
Product Description | Deoxycorticosterone acetate is a steroid hormone used for intramuscular injection for replacement therapy of the adrenocortical steroid. |
ALogP | 3.1 |
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IUPAC Name | [2-[(8S,9S,10R,13S,14S,17S)-10,13-dimethyl-3-oxo-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate |
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INCHI | InChI=1S/C23H32O4/c1-14(24)27-13-21(26)20-7-6-18-17-5-4-15-12-16(25)8-10-22(15,2)19(17)9-11-23(18,20)3/h12,17-20H,4-11,13H2,1-3H3/t17-,18-,19-,20+,22-,23-/m0/s1 |
InChi Key | VPGRYOFKCNULNK-ACXQXYJUSA-N |
Canonical SMILES | CC(=O)OCC(=O)C1CCC2C1(CCC3C2CCC4=CC(=O)CCC34C)C |
Isomeric SMILES | CC(=O)OCC(=O)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CCC4=CC(=O)CC[C@]34C)C |
WGK Germany | 3 |
RTECS | HG0525000 |
PubChem CID | 5952 |
Molecular Weight | 372.5 |
Beilstein | 2570798 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
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I2209260 | Certificate of Analysis | Jun 14, 2024 | D129628 |
I2209261 | Certificate of Analysis | Jun 14, 2024 | D129628 |
G2426329 | Certificate of Analysis | Jun 11, 2024 | D129628 |
G2426330 | Certificate of Analysis | Jun 11, 2024 | D129628 |
L2102567 | Certificate of Analysis | Sep 18, 2023 | D129628 |
D2412088 | Certificate of Analysis | May 19, 2023 | D129628 |
F2302670 | Certificate of Analysis | May 19, 2023 | D129628 |
F2302675 | Certificate of Analysis | May 19, 2023 | D129628 |
F2302676 | Certificate of Analysis | May 19, 2023 | D129628 |
F2302677 | Certificate of Analysis | May 19, 2023 | D129628 |
F2302683 | Certificate of Analysis | May 19, 2023 | D129628 |
F2116113 | Certificate of Analysis | Apr 11, 2023 | D129628 |
F1509082 | Certificate of Analysis | Jan 16, 2023 | D129628 |
D2313821 | Certificate of Analysis | Jul 22, 2022 | D129628 |
Solubility | Soluble in methanol, ethanol (6 mg/mL at 25 °C), chloroform (100 mg/mL), and DMSO (11 mg/mL at 25 °C). Insoluble in water. |
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Specific Rotation[α] | 20/D: +170.0 to +180.0 deg(C=1, Dioxane) |
Melt Point(°C) | 157°C |
Pictogram(s) | GHS08 |
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Signal | Danger |
Hazard Statements | H373:Causes damage to organs through prolonged or repeated exposure H360:May damage fertility or the unborn child |
Precautionary Statements | P280:Wear protective gloves/protective clothing/eye protection/face protection. P405:Store locked up. P501:Dispose of contents/container to ... P260:Do not breathe dust/fume/gas/mist/vapors/spray. P203:Obtain, read and follow all safety instructions before use. P318:if exposed or concerned, get medical advice. P319:Get medical help if you feel unwell. |
WGK Germany | 3 |
RTECS | HG0525000 |
1. Hao Jiameng, Chang Liping, Wang Dandong, Ji Chuanyuan, Zhang Shaolan, Hou Yunlong, Wu Yiling. (2023) Periplocin Alleviates Cardiac Remodeling in DOCA-Salt–Induced Heart Failure Rats. Journal of Cardiovascular Translational Research, 16 (1): (127-140). [PMID:35616880] |
1. Hao Jiameng, Chang Liping, Wang Dandong, Ji Chuanyuan, Zhang Shaolan, Hou Yunlong, Wu Yiling. (2023) Periplocin Alleviates Cardiac Remodeling in DOCA-Salt–Induced Heart Failure Rats. Journal of Cardiovascular Translational Research, 16 (1): (127-140). [PMID:35616880] |