Grouped product items

SKU

Size

Availability

Price

Qty

D339696-1mg

1mg

In stock

$88.90

D339696-5mg

5mg

In stock

$227.90

D339696-25mg

25mg

In stock

$1,021.90

Basic Description

Synonyms	Deoxymannojirimycin \| 1-Deoxymannojirimycin \| 84444-90-6 \| 1hxk \| (2R,3R,4R,5R)-2-(hydroxymethyl)piperidine-3,4,5-triol \| D-manno-Deoxynojirimycin \| CHEMBL84844 \| DMJ \| (2R,3R,4R,5R)-2-(Hydroxymethyl)-3,4,5-piperidinetriol \| LU 1 \| Ox5 \| D-Deoxymannojirimycin \| NSC625109 \| 1fo2 \| 3,
Specifications & Purity	≥98%
Storage Temp	Store at -20°C,Argon charged
Shipped In	Ice chest + Ice pads
Product Description	Deoxymannojirimycin HCl is a mannose analog that inhibits mammalian MAN1A2 (Golgi-alpha-mannosidase I) at the active site. Known to block the biosynthesis of complex oligosaccharides. However, it does not block endoplasmic reticulum alpha-mannosidase. Observed to induce disorganization of the extracellular matrix fibronectin assembly. Also, deoxymannojirimycin treated in hepatocarcinoma H7721 cells resulted in ER stress and apoptosis.

Associated Targets(Human)

GBA3 Tbio Cytosolic beta-glucosidase (0 Activities)

Discover Target: GBA3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

FUCA1 Tchem Tissue alpha-L-fucosidase (0 Activities)

Discover Target: FUCA1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

HDAC6 Tclin Histone deacetylase 6 (0 Activities)

Discover Target: HDAC6

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

GAA Tclin Lysosomal alpha-glucosidase (0 Activities)

Discover Target: GAA

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

MANBA Tchem Beta-mannosidase (0 Activities)

Discover Target: MANBA

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

MGAM Tclin Maltase-glucoamylase, intestinal (0 Activities)

Discover Target: MGAM

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

MAN2B1 Tchem Lysosomal alpha-mannosidase (0 Activities)

Discover Target: MAN2B1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

MAN2B2 Tbio Epididymis-specific alpha-mannosidase (0 Activities)

Discover Target: MAN2B2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

JAK1 Tclin Tyrosine-protein kinase JAK1 (0 Activities)

Discover Target: JAK1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

GLB1 Tchem Beta-galactosidase (0 Activities)

Discover Target: GLB1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

GLA Tclin Alpha-galactosidase A (0 Activities)

Discover Target: GLA

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

SI Tchem Sucrase-isomaltase, intestinal (0 Activities)

Discover Target: SI

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

THRB Tclin Thyroid hormone receptor beta (0 Activities)

Discover Target: THRB

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

GANAB Tchem Neutral alpha-glucosidase AB (0 Activities)

Discover Target: GANAB

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

MGAM Tclin Maltase-glucoamylase (654 Activities)

Discover Target: MGAM

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

THRB Tclin Thyroid hormone receptor beta-1 (7926 Activities)

Discover Target: THRB

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

GLB1 Tchem Beta-galactosidase (339 Activities)

Discover Target: GLB1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

GLA Tclin Alpha-galactosidase A (5444 Activities)

Discover Target: GLA

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

GANAB Tchem Neutral alpha-glucosidase AB (90 Activities)

Discover Target: GANAB

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

JAK1 Tclin Tyrosine-protein kinase JAK1 (8569 Activities)

Discover Target: JAK1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

GAA Tclin Lysosomal alpha-glucosidase (35701 Activities)

Discover Target: GAA

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

MANBA Tchem Beta-mannosidase (62 Activities)

Discover Target: MANBA

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

FUCA1 Tchem Alpha-L-fucosidase I (304 Activities)

Discover Target: FUCA1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

MAN2B1 Tchem Lysosomal alpha-mannosidase (172 Activities)

Discover Target: MAN2B1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

GBA3 Tbio Beta-glucosidase cytosolic (63 Activities)

Discover Target: GBA3

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SI Tchem Sucrase-isomaltase (84 Activities)

Discover Target: SI

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

MAN2B2 Tbio Epididymis-specific alpha-mannosidase (14 Activities)

Discover Target: MAN2B2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PBMC (10003 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

Hdac6 Histone deacetylase 6 (222 Activities)

Discover Target: Hdac6

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

GAA Alpha-glucosidase (25 Activities)

Discover Target: GAA

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

aglC Alpha-galactosidase C (14 Activities)

Discover Target: aglC

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

melA Alpha-galactosidase (10 Activities)

Discover Target: melA

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Man1 Alpha-mannosidase (188 Activities)

Discover Target: Man1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

FUCA1 Alpha-L-fucosidase 1 (358 Activities)

Discover Target: FUCA1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

rep Replicase polyprotein 1ab (378 Activities)

Discover Target: rep

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

GH92 alpha-mannosidase (372 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SARS-CoV-2 (38078 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Names and Identifiers

IUPAC Name	(2R,3R,4R,5R)-2-(hydroxymethyl)piperidine-3,4,5-triol
INCHI	InChI=1S/C6H13NO4/c8-2-3-5(10)6(11)4(9)1-7-3/h3-11H,1-2H2/t3-,4-,5-,6-/m1/s1
InChi Key	LXBIFEVIBLOUGU-KVTDHHQDSA-N
Canonical SMILES	C1C(C(C(C(N1)CO)O)O)O
Isomeric SMILES	C1[C@H]([C@H]([C@@H]([C@H](N1)CO)O)O)O
WGK Germany	3
PubChem CID	72258
Molecular Weight	199.6

Certificates

Certificate of Analysis(COA)

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3 results found

Lot Number	Certificate Type	Date	Item
F2218478	Certificate of Analysis	Jun 06, 2022	D339696
F2218485	Certificate of Analysis	Jun 06, 2022	D339696
F2218486	Certificate of Analysis	Jun 06, 2022	D339696

Chemical and Physical Properties

Solubility	Soluble in water (50 mM), methanol (warm), and DMSO.
Refractive Index	n20D1.58
Boil Point(°C)	361.1° C at 760 mmHg
Melt Point(°C)	197.5-198.7° C

Safety and Hazards(GHS)

WGK Germany	3

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Deoxymannojirimycin hydrochloride - ≥98%, high purity , CAS No.84444-90-6

Basic Description

Associated Targets(Human)

Associated Targets(non-human)

Names and Identifiers

Certificates

Certificate of Analysis(COA)

Chemical and Physical Properties

Safety and Hazards(GHS)

Related Documents

Solution Calculators

Molarity Calculator

Dilution Calculator

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