Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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SKU | Size | Availability | Price | Qty |
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D134376-5mg | 5mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $11.90 | |
D134376-25mg | 25mg | In stock | $48.90 | |
D134376-50mg | 50mg | In stock | $78.90 | |
D134376-100mg | 100mg | In stock | $127.90 | |
D134376-200mg | 200mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $283.90 | |
D134376-250mg | 250mg | In stock | $288.90 | |
D134376-1g | 1g | In stock | $1,036.90 | |
D134376-5g | 5g | In stock | $4,665.90 | |
D134376-25g | 25g | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $20,995.90 |
Synonyms | HY-B0581 | NCGC00263544-01 | Triperazine | EN300-7356981 | NCGC00263544-02 | Transamine | (+)-dexrazoxane | 048L81261F | Dexrazoxano [INN-Spanish] | Zinecard | DEXRAZOXANE [VANDF] | NCGC00164737-01 | Soluble ICRF (L-isomer) | BIDD:GT0068 | Dexrazoxano (IN |
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Specifications & Purity | Moligand™, ≥97% |
Storage Temp | Store at 2-8°C |
Shipped In | Wet ice |
Grade | Moligand™ |
Action Type | SEQUESTERING AGENT |
Mechanism of action | DNA topoisomerase II inhibitor |
ALogP | -1.4 |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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IUPAC Name | 4-[(2S)-2-(3,5-dioxopiperazin-1-yl)propyl]piperazine-2,6-dione |
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INCHI | InChI=1S/C11H16N4O4/c1-7(15-5-10(18)13-11(19)6-15)2-14-3-8(16)12-9(17)4-14/h7H,2-6H2,1H3,(H,12,16,17)(H,13,18,19)/t7-/m0/s1 |
InChi Key | BMKDZUISNHGIBY-ZETCQYMHSA-N |
Canonical SMILES | CC(CN1CC(=O)NC(=O)C1)N2CC(=O)NC(=O)C2 |
Isomeric SMILES | C[C@@H](CN1CC(=O)NC(=O)C1)N2CC(=O)NC(=O)C2 |
WGK Germany | 3 |
PubChem CID | 71384 |
Molecular Weight | 268.27 |
DrugBank Ligand | DB00380 |
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PubChem CID | 71384 |
CAS Registry No. | 24584-09-6 |
ChEMBL Ligand | CHEMBL1738 |
Wikipedia | Dexrazoxane |
DrugCentral Ligand | 839 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
---|---|---|---|
L2419408 | Certificate of Analysis | Dec 25, 2024 | D134376 |
E1712021 | Certificate of Analysis | Sep 06, 2024 | D134376 |
C2203109 | Certificate of Analysis | Dec 12, 2023 | D134376 |
C2203166 | Certificate of Analysis | Dec 12, 2023 | D134376 |
C2203168 | Certificate of Analysis | Dec 12, 2023 | D134376 |
C2203185 | Certificate of Analysis | Dec 12, 2023 | D134376 |
C2203246 | Certificate of Analysis | Dec 12, 2023 | D134376 |
C2203251 | Certificate of Analysis | Dec 12, 2023 | D134376 |
C2203253 | Certificate of Analysis | Dec 12, 2023 | D134376 |
Solubility | Soluble in Dimethylformamide; Slightly soluble in Ethanol,Methanol |
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Specific Rotation[α] | 11° (C=5,DMF) |
Melt Point(°C) | 195 °C |
Pictogram(s) | GHS07 |
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Signal | Warning |
Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation |
Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell. |
WGK Germany | 3 |
Merck Index | 8123 |
1. Shanshan Wei, Wanjun Ma, Chuanhao Jiang, Jiaqin Liu, Jian Liu, Bikui Zhang, Wenqun Li. (2023) Hyperoside prevents doxorubicin-induced cardiotoxicity by inhibiting NOXs/ROS/NLRP3 inflammasome signaling pathway. PHYTOTHERAPY RESEARCH, [PMID:37246409] [10.1002/ptr.7900] |
1. Shanshan Wei, Wanjun Ma, Chuanhao Jiang, Jiaqin Liu, Jian Liu, Bikui Zhang, Wenqun Li. (2023) Hyperoside prevents doxorubicin-induced cardiotoxicity by inhibiting NOXs/ROS/NLRP3 inflammasome signaling pathway. PHYTOTHERAPY RESEARCH, [PMID:37246409] [10.1002/ptr.7900] |