Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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SKU | Size | Availability | Price | Qty |
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D287750-10mg | 10mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $122.90 | |
D287750-50mg | 50mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $497.90 |
Topoisomerase II inhibitor
Synonyms | Dexrazoxane hydrochloride | 149003-01-0 | Dexrazoxane HCl | Totect | Cardioxane | Cardioxan | Savene | Zinecard | ADR-529 hydrochloride | ICRF-187 hydrochloride | 1263283-43-7 | ICRF-187 | ICRF 187 hydrochloride | Dexrazoxane (Hydrochloride) | (+)-Razoxane hydrochloride | Razoxane hyd |
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Specifications & Purity | ≥98%(HPLC) |
Biochemical and Physiological Mechanisms | Topoisomerase II inhibitor and intracellular ion chelator. Bridges and stabilizes an interface between two ATPase promoters to inhibit topoisomerase II activity. Cardioprotective when co-administered with doxorubicin; decreases formation of reactive oxyge |
Storage Temp | Room temperature,Desiccated |
Shipped In | Normal |
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IUPAC Name | 4-[(2S)-2-(3,5-dioxopiperazin-1-yl)propyl]piperazine-2,6-dione;hydrochloride |
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INCHI | InChI=1S/C11H16N4O4.ClH/c1-7(15-5-10(18)13-11(19)6-15)2-14-3-8(16)12-9(17)4-14;/h7H,2-6H2,1H3,(H,12,16,17)(H,13,18,19);1H/t7-;/m0./s1 |
InChi Key | BIFMNMPSIYHKDN-FJXQXJEOSA-N |
Canonical SMILES | CC(CN1CC(=O)NC(=O)C1)N2CC(=O)NC(=O)C2.Cl |
Isomeric SMILES | C[C@@H](CN1CC(=O)NC(=O)C1)N2CC(=O)NC(=O)C2.Cl |
PubChem CID | 6918223 |
Molecular Weight | 304.73 |
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Solubility | Solvent:water, Max Conc. mg/mL: 30.47, Max Conc. mM: 100; Solvent:DMSO, Max Conc. mg/mL: 30.47, Max Conc. mM: 100 |
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