Dexrazoxane hydrochloride - ≥98%(HPLC), high purity , CAS No.1263283-43-7

  • ≥98%(HPLC)
Item Number
D287750
Grouped product items
SKUSizeAvailabilityPrice Qty
D287750-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$122.90
D287750-50mg
50mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$497.90

Topoisomerase II inhibitor

Basic Description

SynonymsDexrazoxane hydrochloride | 149003-01-0 | Dexrazoxane HCl | Totect | Cardioxane | Cardioxan | Savene | Zinecard | ADR-529 hydrochloride | ICRF-187 hydrochloride | 1263283-43-7 | ICRF-187 | ICRF 187 hydrochloride | Dexrazoxane (Hydrochloride) | (+)-Razoxane hydrochloride | Razoxane hyd
Specifications & Purity≥98%(HPLC)
Biochemical and Physiological MechanismsTopoisomerase II inhibitor and intracellular ion chelator. Bridges and stabilizes an interface between two ATPase promoters to inhibit topoisomerase II activity. Cardioprotective when co-administered with doxorubicin; decreases formation of reactive oxyge
Storage TempRoom temperature,Desiccated
Shipped InNormal

Associated Targets(Human)

ENGASE Tchem Endo-beta-N-acetylglucosaminidase (63 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SARS-CoV-2 (38078 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Names and Identifiers

IUPAC Name 4-[(2S)-2-(3,5-dioxopiperazin-1-yl)propyl]piperazine-2,6-dione;hydrochloride
INCHI InChI=1S/C11H16N4O4.ClH/c1-7(15-5-10(18)13-11(19)6-15)2-14-3-8(16)12-9(17)4-14;/h7H,2-6H2,1H3,(H,12,16,17)(H,13,18,19);1H/t7-;/m0./s1
InChi Key BIFMNMPSIYHKDN-FJXQXJEOSA-N
Canonical SMILES CC(CN1CC(=O)NC(=O)C1)N2CC(=O)NC(=O)C2.Cl
Isomeric SMILES C[C@@H](CN1CC(=O)NC(=O)C1)N2CC(=O)NC(=O)C2.Cl
PubChem CID 6918223
Molecular Weight 304.73

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

SolubilitySolvent:water, Max Conc. mg/mL: 30.47, Max Conc. mM: 100; Solvent:DMSO, Max Conc. mg/mL: 30.47, Max Conc. mM: 100

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Solution Calculators