Dextran sulfate sodium salt - M.W 100,000, high purity , CAS No.9011-18-1

29 Citations
  • M.W 100,000
Item Number
D292253
Grouped product items
SKUSizeAvailabilityPrice Qty
D292253-5g
5g
In stock
$315.90
D292253-10g
10g
In stock
$573.90
D292253-25g
25g
In stock
$1,716.90
D292253-50g
50g
In stock
$2,746.90

Basic Description

Synonymsbenzocaine | Ethyl 4-aminobenzoate | 94-09-7 | Ethyl aminobenzoate | Ethyl p-aminobenzoate | Parathesin | Norcaine | Americaine | Anaesthesin | Anesthesin | Parathesine | 4-Aminobenzoic acid ethyl ester | Amben ethyl ester | p-Carbethoxyaniline | Anaesthin | Anesthesine | Dermoplast | Eth
Specifications & PurityM.W 100,000
Biochemical and Physiological MechanismsGlucose sulfate inhibits the replication of human immunodeficiency viruses by preventing the virus from adsorption into host cells.
Storage TempStore at 2-8°C,Argon charged
Shipped InWet ice
Product Description

Dextran sulfate is supplied as a white powder which dissolves freely in water or salt solutions giving a clear solution.

Dextran sulfates may be produced with a wide range of molecular weights and degrees of sulfation. Each of the products within this range is supplied with sulphur contents of 16-20%. Dextran sulfates act as potent polyanions and offer many interesting pharmacological and biophysical properties. Dextran sulfates are produced by sulfating selected dextran fractions. The dextran sulfate is supplied as the sodium salt and is stabilised by a small addition of phosphate salts. A certificate of analysis is supplied with each batch. The molecular weight range, sulfur content, moisture etc. are carefully controlled. Dextran is a polysaccharide derived from the bacterium Leuconostoc mesenteroides B512F and consists of an α-D-(1 – 6) linear glucan with a low content (ca. 5%) of sidechains linked to the 3-carbon of glucose. Dextran sulfate is a sulfated derivative of selected dextran fraction. 


Applications

Dextran sulfate have a wide range of applications areas and properties. Some examples are:

Anti-coagulation agent in cell media

Selective precipitation of lipoproteins

Acceleration of DNA hybridisation.

Releasing DNA from DNA-histones complexes

Inhibition tRNA-binding to ribosomes

Inhibition of ribonucleases

Anti-viral properties

Used in cosmetics for anti-inflammation properties and osmotic retention of water

Separation of microorganisms and macromolecules

Adjuvant in vaccines

Studies of perm selectivity of membranes

Product Properties

ALogP1.9

Associated Targets(Human)

CTH Tchem Cystathionine gamma-lyase (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CYP1A2 Tchem Cytochrome P450 1A2 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
DRD2 Tclin D(2) dopamine receptor (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
DRD4 Tchem D(4) dopamine receptor (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CYP3A4 Tclin Cytochrome P450 3A4 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ERBB2 Tclin Receptor tyrosine-protein kinase erbB-2 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
GABRA1 Tclin Gamma-aminobutyric acid receptor subunit alpha-1 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ELANE Tclin Neutrophil elastase (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
EGFR Tclin Epidermal growth factor receptor (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
AVPR1A Tclin Vasopressin V1a receptor (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
HMGCR Tclin 3-hydroxy-3-methylglutaryl-coenzyme A reductase (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
HDAC6 Tclin Histone deacetylase 6 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
HRH1 Tclin Histamine H1 receptor (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
SLCO1B3 Tchem Solute carrier organic anion transporter family member 1B3 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
SLC6A3 Tclin Sodium-dependent dopamine transporter (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
SLC6A4 Tclin Sodium-dependent serotonin transporter (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
SIGMAR1 Tclin Sigma non-opioid intracellular receptor 1 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
PDE4D Tclin cAMP-specific 3',5'-cyclic phosphodiesterase 4D (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
PTGS1 Tclin Prostaglandin G/H synthase 1 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CA2 Tclin Carbonic anhydrase 2 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
DRD3 Tclin D(3) dopamine receptor (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CHRM3 Tclin Muscarinic acetylcholine receptor M3 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CHRM4 Tclin Muscarinic acetylcholine receptor M4 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ADRA2B Tclin Alpha-2B adrenergic receptor (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ADRA2C Tclin Alpha-2C adrenergic receptor (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
HTR2A Tclin 5-hydroxytryptamine receptor 2A (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ADORA2A Tclin Adenosine receptor A2a (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ACHE Tclin Acetylcholinesterase (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ADRA1B Tclin Alpha-1B adrenergic receptor (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ADRA1A Tclin Alpha-1A adrenergic receptor (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
AR Tclin Androgen receptor (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
MAOA Tclin Amine oxidase [flavin-containing] A (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
AKR1B1 Tclin Aldose reductase (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ADORA1 Tclin Adenosine receptor A1 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
HTR1A Tclin 5-hydroxytryptamine receptor 1A (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ADORA3 Tchem Adenosine receptor A3 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
HTR3A Tclin 5-hydroxytryptamine receptor 3A (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
HTR6 Tchem 5-hydroxytryptamine receptor 6 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
HTR2B Tclin 5-hydroxytryptamine receptor 2B (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
EDNRA Tclin Endothelin-1 receptor (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
KCNH2 Tclin Potassium voltage-gated channel subfamily H member 2 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
OPRD1 Tclin Delta-type opioid receptor (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
OPRK1 Tclin Kappa-type opioid receptor (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
OPRM1 Tclin Mu-type opioid receptor (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
NOS2 Tchem Nitric oxide synthase, inducible (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
TACR1 Tclin Substance-P receptor (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
NOS1 Tchem Nitric oxide synthase, brain (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
PDE5A Tclin Phosphodiesterase 5A (5113 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
EGFR Tclin Epidermal growth factor receptor erbB1 (33727 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CA2 Tclin Carbonic anhydrase II (17698 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ESR1 Tclin Estrogen receptor alpha (17718 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HMGCR Tclin HMG-CoA reductase (2475 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
NR3C1 Tclin Glucocorticoid receptor (14987 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
INSR Tclin Insulin receptor (5558 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PGR Tclin Progesterone receptor (8562 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRB2 Tclin Beta-2 adrenergic receptor (11824 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CHRM2 Tclin Muscarinic acetylcholine receptor M2 (10671 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRB1 Tclin Beta-1 adrenergic receptor (6630 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HTR1A Tclin Serotonin 1a (5-HT1a) receptor (14969 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRA2A Tclin Alpha-2a adrenergic receptor (9450 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
AR Tclin Androgen Receptor (11781 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CHRM1 Tclin Muscarinic acetylcholine receptor M1 (12690 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ACE Tclin Angiotensin-converting enzyme (1423 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DRD2 Tclin Dopamine D2 receptor (23596 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GABRA1 Tclin GABA receptor alpha-1 subunit (399 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MAOA Tclin Monoamine oxidase A (11911 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CNR1 Tclin Cannabinoid CB1 receptor (20913 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DRD1 Tclin Dopamine D1 receptor (9720 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DRD4 Tchem Dopamine D4 receptor (7907 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ACHE Tclin Acetylcholinesterase (18204 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PTGS1 Tclin Cyclooxygenase-1 (9233 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLC6A2 Tclin Norepinephrine transporter (10102 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HRH2 Tclin Histamine H2 receptor (5428 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRA1D Tclin Alpha-1d adrenergic receptor (4171 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HTR1B Tclin Serotonin 1b (5-HT1b) receptor (2801 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HTR2A Tclin Serotonin 2a (5-HT2a) receptor (14758 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HTR2C Tclin Serotonin 2c (5-HT2c) receptor (11471 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
AVPR2 Tclin Vasopressin V2 receptor (2912 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADORA1 Tclin Adenosine A1 receptor (17603 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
AGTR1 Tclin Type-1 angiotensin II receptor (5176 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CALCR Tclin Calcitonin receptor (2215 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLC6A4 Tclin Serotonin transporter (12625 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRA1A Tclin Alpha-1a adrenergic receptor (8359 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PTGS2 Tclin Cyclooxygenase-2 (13999 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HRH1 Tclin Histamine H1 receptor (7573 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRA1B Tclin Alpha-1b adrenergic receptor (2912 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
OPRM1 Tclin Mu opioid receptor (19785 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DRD3 Tclin Dopamine D3 receptor (14368 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
AVPR1A Tclin Vasopressin V1a receptor (5412 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
OPRD1 Tclin Delta opioid receptor (15096 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
OPRK1 Tclin Kappa opioid receptor (16155 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HTR3A Tclin Serotonin 3a (5-HT3a) receptor (3366 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLC6A3 Tclin Dopamine transporter (10535 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GRIN1 Tclin Glutamate (NMDA) receptor subunit zeta 1 (122 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KCNH2 Tclin HERG (29587 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HTR4 Tclin Serotonin 4 (5-HT4) receptor (2068 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CACNA1C Tclin Voltage-gated L-type calcium channel alpha-1C subunit (766 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Agtr2 Angiotensin II type 2 (AT-2) receptor (803 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mc4r Melanocortin receptor 4 (1205 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Ltc4s Leukotriene C4 synthase (1 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Sigmar1 Sigma opioid receptor (160 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Npy1r Neuropeptide Y receptor type 1 (8 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Cckar Cholecystokinin A receptor (90 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Pde4d Phosphodiesterase 4D (4 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Abcb1b P-glycoprotein 1 (174 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Nos2 Nitric oxide synthase, inducible (3573 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mapk1 MAP kinase ERK2 (650 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Hdac6 Histone deacetylase 6 (222 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mmp9 Matrix metalloproteinase 9 (38 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Plasmodium falciparum (966862 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Rattus norvegicus (775804 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Rorc Nuclear receptor ROR-gamma (89407 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Scn2a Sodium channel alpha subunits; brain (Types I, II, III) (344 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Whole blood (71 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Glra2 Glycine receptor (1745 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SARS-CoV-2 (38078 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Names and Identifiers

IUPAC Name ethyl 4-aminobenzoate
INCHI InChI=1S/C9H11NO2/c1-2-12-9(11)7-3-5-8(10)6-4-7/h3-6H,2,10H2,1H3
InChi Key BLFLLBZGZJTVJG-UHFFFAOYSA-N
Isomeric SMILES CCOC(=O)C1=CC=C(C=C1)N
WGK Germany 2
RTECS HH9290000
PubChem CID 2337

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

4 results found

Lot NumberCertificate TypeDateItem
L2215427Certificate of AnalysisNov 14, 2022 D292253
L2215437Certificate of AnalysisNov 14, 2022 D292253
L2215464Certificate of AnalysisNov 14, 2022 D292253
L2215484Certificate of AnalysisNov 14, 2022 D292253

Chemical and Physical Properties

Solubilityreadily soluble in water.
SensitivityMoisture sensitive
Specific Rotation[α]93° (C=6,H2O)

Safety and Hazards(GHS)

Pictogram(s) GHS08,   GHS07
Signal Danger
Hazard Statements

H319:Causes serious eye irritation

H317:May cause an allergic skin reaction

H370:Causes damage to organs

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P260:Do not breathe dust/fume/gas/mist/vapors/spray.

P270:Do not eat, drink or smoke when using this product.

P272:Contaminated work clothing should not be allowed out of the workplace.

P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention.

P362+P364:Take off contaminated clothing and wash it before reuse.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P337+P317:If eye irritation persists: Get medical help.

P308+P316:IF exposed or concerned: Get emergency medical help immediately.

WGK Germany 2
RTECS HH9290000
Merck Index 2951

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2. Yue Wu, Xiaoyu Liang, Canquan Mao, Yuhong Jiang.  (2023)  The Distinct Properties of Polysaccharide Nanoparticles Tune Immune Responses against mRNA Antigen via Stimulator of Interferon Genes-Mediated Autophagy and Inflammasome.  ACS Nano,  17  (21): (21782–21798).  [PMID:37922196]
3. Nan Li, Ruiyan Wang, Wenwen Li, Qian Du, Zeyuan deng, Yawei Fan, Liufeng Zheng.  (2023)  Identification of OLA1 as a Novel Protein Target of Vitexin to Ameliorate Dextran Sulfate Sodium-Induced Colitis with Tissue Thermal Proteome Profiling.  JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,      [PMID:37856434]
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5. Jing Li, Fangzhou Dou, Shasha Hu, Jianjun Gao.  (2023)  Involvement of adaptive immune responses in a model of subacute colitis induced with dextran sulfate sodium in C57BL/6 mice.  Drug Discoveries and Therapeutics,  17  (4): (294-298).  [PMID:37438111]
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8. Bingqing Zhang, Qiang Li, Qinglin Xu, Baochao Li, Heng Dong, Yongbin Mou.  (2023)  Polydopamine Modified Ceria Nanorods Alleviate Inflammation in Colitis by Scavenging ROS and Regulating Macrophage M2 Polarization.  International Journal of Nanomedicine,      [PMID:37600119]
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11. Yan Yang, Mingyuan Li, Hairui Yu, Yi Tong, Qiqing Chen.  (2023)  Effects of fibrous microplastics on the accumulation of tris(2,3-dibromopropyl) isocyanurate and behavior of zebrafish via water- and foodborne exposure routes.  SCIENCE OF THE TOTAL ENVIRONMENT,  892  (164389).  [PMID:37236466]
12. Zhijie Wen, Li Kang, Hudie Fu, Shengpeng Zhu, Xuexin Ye, Xuedan Yang, Shangwen Zhang, Jie Hu, Xiaojun Li, Lvyi Chen, Yan Hu, Xinzhou Yang.  (2023)  Oral delivery of porous starch-loaded bilayer microgels for controlled drug delivery and treatment of ulcerative colitis.  CARBOHYDRATE POLYMERS,  314  (120887).  [PMID:37173037]
13. Huang Rong, Yao Jiaxu, Zhou Li, Li Xiang, Zhu Jinrui, Hu Yueqi, Liu Jikai.  (2023)  Protective effect and mechanism insight of purified Antarctic krill phospholipids against mice ulcerative colitis combined with bioinformatics.  Natural Products and Bioprospecting,  13  (1): (1-12).  [PMID:37016023]
14. Sili Zheng, Dongning Zhang, Bailu Duan, Guoyan Mo, Jingjing Li, Hailing Huang, Shanshan Wang, Yan Ye, Zhuang Huang, Ping Huang, Fengyun Zhang, Fang Huang, Lintao Han.  (2023)  Metabolomics integrated network pharmacology reveals the mechanism of Ma-Mu-Ran Antidiarrheal Capsules on acute enteritis mice.  ANALYTICAL BIOCHEMISTRY,  668  (115116).  [PMID:36925055]
15. Zirong Li, Biaobiao Yan, Leilei Wu, Bo Xu, Li Cui, Yuanyuan Yu, Ping Wang.  (2023)  DS-guided deposition of PEDOT onto silk fabrics for rapid photothermal antibacterial and respiratory sensing.  COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS,  666  (131285).  [PMID:]
16. Hu Xiaoming, Jiao Fuxin, Deng Jiali, Zhou Ziheng, Chen Shanghai, Liu Changqin, Liu Zhanju, Guo Feifan.  (2023)  Intestinal Epithelial Cell-specific Deletion of Cytokine-inducible SH2-containing Protein Alleviates Experimental Colitis in Ageing Mice.  Journal of Crohns & Colitis,  17  (8): (1278-1290).  [PMID:36881790]
17. Wei Sun, Yingxuan Chen, Liang Wang, Ze Wang, Shuwei Liu, Mengzhu Zhang, Yi Liu, Quanshun Li, Hao Zhang.  (2023)  Gram-scale preparation of quercetin supramolecular nanoribbons for intestinal inflammatory diseases by oral administration.  BIOMATERIALS,  295  (122039).  [PMID:36791522]
18. Caihong Wang, Zihong Pan, Yuanxiang Jin.  (2023)  F–53B induces hepatotoxic effects and slows self-healing in ulcerative colitis in mice.  ENVIRONMENTAL POLLUTION,  317  (120819).  [PMID:36481465]
19. Jinyu An, Xue Jiang, Zhe Wang, Yingqiao Li, Zhiru Zou, Qian Wu, Le Tong, Xifan Mei, He Tian, Chao Wu.  (2022)  Codelivery of minocycline hydrochloride and dextran sulfate via bionic liposomes for the treatment of spinal cord injury.  INTERNATIONAL JOURNAL OF PHARMACEUTICS,  628  (122285).  [PMID:36244559]
20. Jiang Tianze, Xie Laozhi, Zhou Songlei, Liu Yipu, Huang Yukun, Mei Ni, Ma Fenfen, Gong Jingru, Gao Xiaoling, Chen Jun.  (2022)  Metformin and histone deacetylase inhibitor based anti-inflammatory nanoplatform for epithelial-mesenchymal transition suppression and metastatic tumor treatment.  JOURNAL OF NANOBIOTECHNOLOGY,  20  (1): (1-21).  [PMID:36045429]
21. Xiang Li, Shijun Xin, Xiaoqun Zheng, Liqin Lou, Shiqing Ye, Shengkai Li, Qilong Wu, Qingyong Ding, Ling Ji, Chunrong Nan, Yongliang Lou.  (2022)  Inhibition of the Occurrence and Development of Inflammation-Related Colorectal Cancer by Fucoidan Extracted from Sargassum fusiforme.  JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,  70  (30): (9463–9476).  [PMID:35858119]
22. Huang Yonggang, Wu Miaomiao, Xiao Hao, Liu Hongnan, Yang Guan.  (2022)  Mesalamine-Mediated Amelioration of Experimental Colitis in Piglets Involves Gut Microbiota Modulation and Intestinal Immune Cell Infiltration.  Frontiers in Immunology,  13    [PMID:35898495]
23. Minghao Zhang, Jinrui Zhu, Li Zhou, Jianquan Kan, Minjie Zhao, Rong Huang, Jikai Liu, Eric Marchioni.  (2022)  Antarctic krill oil high internal phase Pickering emulsion stabilized by bamboo protein gels and the anti-inflammatory effect in vitro and in vivo.  Journal of Functional Foods,  94  (105134).  [PMID:]
24. Jin Liang, Qian Tao, Zhu Tao, Wang Ren-Liang, Chen Wei-Guo, Jiang Hua, Cui Zhi-Hua.  (2022)  Synthesis, Application, and Recovery of Alkali-Clearable Disperse Dyes Containing Azo Pyridone Structure.  FIBERS AND POLYMERS,  23  (4): (1040-1049).  [PMID:]
25. Yuanfang Kong, Yulong Hu, Jieming Li, Juntao Cai, Yuanhao Qiu, Chunhong Dong.  (2022)  Anti-inflammatory Effect of a Novel Pectin Polysaccharide From Rubus chingii Hu on Colitis Mice.  Frontiers in Nutrition,  (868657).  [PMID:35571944]
26. Si-Yuan Lu, Yang Liu, Shijie Tang, Wancong Zhang, Qiuyong Yu, Changqi Shi, Kit-Leong Cheong.  (2022)  Gracilaria lemaneiformis polysaccharides alleviate colitis by modulating the gut microbiota and intestinal barrier in mice.  Food Chemistry-X,  13  (100197).  [PMID:35498989]
27. Ping Zhang, Le Su, Feifan Ma, Xiuyu Ji, Yue Su, Qiulin Yue, Chen Zhao, Song Zhang, Xin Sun, Lin Zhao.  (2022)  Weilan gum oligosaccharide ameliorates dextran sulfate sodium‑induced experimental ulcerative colitis.  Molecular Medicine Reports,  25  (2): (1-11).  [PMID:34913079]
28. Jing Yang, Jinzhe Zhou, Yingying Zhao, Liangchen Zhu, Guanghong Luo, BuJun Ge.  (2021)  Hollow CeO2 with ROS-Scavenging Activity to Alleviate Colitis in Mice.  International Journal of Nanomedicine,      [PMID:34675513]
29. Qing Wang,Mao Ye,Li Xu,Zhi-guo Shi.  (2015-09-01)  A reversed-phase/hydrophilic interaction mixed-mode C18-Diol stationary phase for multiple applications..  Analytica chimica acta,  888  (182-190).  [PMID:26320974]

References

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13. Huang Rong, Yao Jiaxu, Zhou Li, Li Xiang, Zhu Jinrui, Hu Yueqi, Liu Jikai.  (2023)  Protective effect and mechanism insight of purified Antarctic krill phospholipids against mice ulcerative colitis combined with bioinformatics.  Natural Products and Bioprospecting,  13  (1): (1-12).  [PMID:37016023]
14. Sili Zheng, Dongning Zhang, Bailu Duan, Guoyan Mo, Jingjing Li, Hailing Huang, Shanshan Wang, Yan Ye, Zhuang Huang, Ping Huang, Fengyun Zhang, Fang Huang, Lintao Han.  (2023)  Metabolomics integrated network pharmacology reveals the mechanism of Ma-Mu-Ran Antidiarrheal Capsules on acute enteritis mice.  ANALYTICAL BIOCHEMISTRY,  668  (115116).  [PMID:36925055]
15. Zirong Li, Biaobiao Yan, Leilei Wu, Bo Xu, Li Cui, Yuanyuan Yu, Ping Wang.  (2023)  DS-guided deposition of PEDOT onto silk fabrics for rapid photothermal antibacterial and respiratory sensing.  COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS,  666  (131285).  [PMID:]
16. Hu Xiaoming, Jiao Fuxin, Deng Jiali, Zhou Ziheng, Chen Shanghai, Liu Changqin, Liu Zhanju, Guo Feifan.  (2023)  Intestinal Epithelial Cell-specific Deletion of Cytokine-inducible SH2-containing Protein Alleviates Experimental Colitis in Ageing Mice.  Journal of Crohns & Colitis,  17  (8): (1278-1290).  [PMID:36881790]
17. Wei Sun, Yingxuan Chen, Liang Wang, Ze Wang, Shuwei Liu, Mengzhu Zhang, Yi Liu, Quanshun Li, Hao Zhang.  (2023)  Gram-scale preparation of quercetin supramolecular nanoribbons for intestinal inflammatory diseases by oral administration.  BIOMATERIALS,  295  (122039).  [PMID:36791522]
18. Caihong Wang, Zihong Pan, Yuanxiang Jin.  (2023)  F–53B induces hepatotoxic effects and slows self-healing in ulcerative colitis in mice.  ENVIRONMENTAL POLLUTION,  317  (120819).  [PMID:36481465]
19. Jinyu An, Xue Jiang, Zhe Wang, Yingqiao Li, Zhiru Zou, Qian Wu, Le Tong, Xifan Mei, He Tian, Chao Wu.  (2022)  Codelivery of minocycline hydrochloride and dextran sulfate via bionic liposomes for the treatment of spinal cord injury.  INTERNATIONAL JOURNAL OF PHARMACEUTICS,  628  (122285).  [PMID:36244559]
20. Jiang Tianze, Xie Laozhi, Zhou Songlei, Liu Yipu, Huang Yukun, Mei Ni, Ma Fenfen, Gong Jingru, Gao Xiaoling, Chen Jun.  (2022)  Metformin and histone deacetylase inhibitor based anti-inflammatory nanoplatform for epithelial-mesenchymal transition suppression and metastatic tumor treatment.  JOURNAL OF NANOBIOTECHNOLOGY,  20  (1): (1-21).  [PMID:36045429]
21. Xiang Li, Shijun Xin, Xiaoqun Zheng, Liqin Lou, Shiqing Ye, Shengkai Li, Qilong Wu, Qingyong Ding, Ling Ji, Chunrong Nan, Yongliang Lou.  (2022)  Inhibition of the Occurrence and Development of Inflammation-Related Colorectal Cancer by Fucoidan Extracted from Sargassum fusiforme.  JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,  70  (30): (9463–9476).  [PMID:35858119]
22. Huang Yonggang, Wu Miaomiao, Xiao Hao, Liu Hongnan, Yang Guan.  (2022)  Mesalamine-Mediated Amelioration of Experimental Colitis in Piglets Involves Gut Microbiota Modulation and Intestinal Immune Cell Infiltration.  Frontiers in Immunology,  13    [PMID:35898495]
23. Minghao Zhang, Jinrui Zhu, Li Zhou, Jianquan Kan, Minjie Zhao, Rong Huang, Jikai Liu, Eric Marchioni.  (2022)  Antarctic krill oil high internal phase Pickering emulsion stabilized by bamboo protein gels and the anti-inflammatory effect in vitro and in vivo.  Journal of Functional Foods,  94  (105134).  [PMID:]
24. Jin Liang, Qian Tao, Zhu Tao, Wang Ren-Liang, Chen Wei-Guo, Jiang Hua, Cui Zhi-Hua.  (2022)  Synthesis, Application, and Recovery of Alkali-Clearable Disperse Dyes Containing Azo Pyridone Structure.  FIBERS AND POLYMERS,  23  (4): (1040-1049).  [PMID:]
25. Yuanfang Kong, Yulong Hu, Jieming Li, Juntao Cai, Yuanhao Qiu, Chunhong Dong.  (2022)  Anti-inflammatory Effect of a Novel Pectin Polysaccharide From Rubus chingii Hu on Colitis Mice.  Frontiers in Nutrition,  (868657).  [PMID:35571944]
26. Si-Yuan Lu, Yang Liu, Shijie Tang, Wancong Zhang, Qiuyong Yu, Changqi Shi, Kit-Leong Cheong.  (2022)  Gracilaria lemaneiformis polysaccharides alleviate colitis by modulating the gut microbiota and intestinal barrier in mice.  Food Chemistry-X,  13  (100197).  [PMID:35498989]
27. Ping Zhang, Le Su, Feifan Ma, Xiuyu Ji, Yue Su, Qiulin Yue, Chen Zhao, Song Zhang, Xin Sun, Lin Zhao.  (2022)  Weilan gum oligosaccharide ameliorates dextran sulfate sodium‑induced experimental ulcerative colitis.  Molecular Medicine Reports,  25  (2): (1-11).  [PMID:34913079]
28. Jing Yang, Jinzhe Zhou, Yingying Zhao, Liangchen Zhu, Guanghong Luo, BuJun Ge.  (2021)  Hollow CeO2 with ROS-Scavenging Activity to Alleviate Colitis in Mice.  International Journal of Nanomedicine,      [PMID:34675513]
29. Qing Wang,Mao Ye,Li Xu,Zhi-guo Shi.  (2015-09-01)  A reversed-phase/hydrophilic interaction mixed-mode C18-Diol stationary phase for multiple applications..  Analytica chimica acta,  888  (182-190).  [PMID:26320974]

Solution Calculators