Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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D292253-5g | 5g | In stock | $315.90 | |
D292253-10g | 10g | In stock | $573.90 | |
D292253-25g | 25g | In stock | $1,716.90 | |
D292253-50g | 50g | In stock | $2,746.90 |
Synonyms | benzocaine | Ethyl 4-aminobenzoate | 94-09-7 | Ethyl aminobenzoate | Ethyl p-aminobenzoate | Parathesin | Norcaine | Americaine | Anaesthesin | Anesthesin | Parathesine | 4-Aminobenzoic acid ethyl ester | Amben ethyl ester | p-Carbethoxyaniline | Anaesthin | Anesthesine | Dermoplast | Eth |
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Specifications & Purity | M.W 100,000 |
Biochemical and Physiological Mechanisms | Glucose sulfate inhibits the replication of human immunodeficiency viruses by preventing the virus from adsorption into host cells. |
Storage Temp | Store at 2-8°C,Argon charged |
Shipped In | Wet ice |
Product Description | Dextran sulfate is supplied as a white powder which dissolves freely in water or salt solutions giving a clear solution. Dextran sulfates may be produced with a wide range of molecular weights and degrees of sulfation. Each of the products within this range is supplied with sulphur contents of 16-20%. Dextran sulfates act as potent polyanions and offer many interesting pharmacological and biophysical properties. Dextran sulfates are produced by sulfating selected dextran fractions. The dextran sulfate is supplied as the sodium salt and is stabilised by a small addition of phosphate salts. A certificate of analysis is supplied with each batch. The molecular weight range, sulfur content, moisture etc. are carefully controlled. Dextran is a polysaccharide derived from the bacterium Leuconostoc mesenteroides B512F and consists of an α-D-(1 – 6) linear glucan with a low content (ca. 5%) of sidechains linked to the 3-carbon of glucose. Dextran sulfate is a sulfated derivative of selected dextran fraction. Applications Dextran sulfate have a wide range of applications areas and properties. Some examples are: Anti-coagulation agent in cell media Selective precipitation of lipoproteins Acceleration of DNA hybridisation. Releasing DNA from DNA-histones complexes Inhibition tRNA-binding to ribosomes Inhibition of ribonucleases Anti-viral properties Used in cosmetics for anti-inflammation properties and osmotic retention of water Separation of microorganisms and macromolecules Adjuvant in vaccines Studies of perm selectivity of membranes |
ALogP | 1.9 |
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IUPAC Name | ethyl 4-aminobenzoate |
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INCHI | InChI=1S/C9H11NO2/c1-2-12-9(11)7-3-5-8(10)6-4-7/h3-6H,2,10H2,1H3 |
InChi Key | BLFLLBZGZJTVJG-UHFFFAOYSA-N |
Isomeric SMILES | CCOC(=O)C1=CC=C(C=C1)N |
WGK Germany | 2 |
RTECS | HH9290000 |
PubChem CID | 2337 |
Enter Lot Number to search for COA:
To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section
Lot Number | Certificate Type | Date | Item |
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L2215427 | Certificate of Analysis | Nov 14, 2022 | D292253 |
L2215437 | Certificate of Analysis | Nov 14, 2022 | D292253 |
L2215464 | Certificate of Analysis | Nov 14, 2022 | D292253 |
L2215484 | Certificate of Analysis | Nov 14, 2022 | D292253 |
Solubility | readily soluble in water. |
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Sensitivity | Moisture sensitive |
Specific Rotation[α] | 93° (C=6,H2O) |
Pictogram(s) | GHS08, GHS07 |
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Signal | Danger |
Hazard Statements | H319:Causes serious eye irritation H317:May cause an allergic skin reaction H370:Causes damage to organs |
Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P260:Do not breathe dust/fume/gas/mist/vapors/spray. P270:Do not eat, drink or smoke when using this product. P272:Contaminated work clothing should not be allowed out of the workplace. P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention. P362+P364:Take off contaminated clothing and wash it before reuse. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P337+P317:If eye irritation persists: Get medical help. P308+P316:IF exposed or concerned: Get emergency medical help immediately. |
WGK Germany | 2 |
RTECS | HH9290000 |
Merck Index | 2951 |
1. Yi Sun, Cheng Zhang, Yu-ting Yang, Hui Yu, Jing-hong Li. (2023) Polarization-Sensitive Asymmetric Scattering at the Single-Particle Scale via Surface Plasmon Resonance Microscopy. ANALYTICAL CHEMISTRY, 95 (51): (18898–18906). [PMID:38096497] |
2. Yue Wu, Xiaoyu Liang, Canquan Mao, Yuhong Jiang. (2023) The Distinct Properties of Polysaccharide Nanoparticles Tune Immune Responses against mRNA Antigen via Stimulator of Interferon Genes-Mediated Autophagy and Inflammasome. ACS Nano, 17 (21): (21782–21798). [PMID:37922196] |
3. Nan Li, Ruiyan Wang, Wenwen Li, Qian Du, Zeyuan deng, Yawei Fan, Liufeng Zheng. (2023) Identification of OLA1 as a Novel Protein Target of Vitexin to Ameliorate Dextran Sulfate Sodium-Induced Colitis with Tissue Thermal Proteome Profiling. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, [PMID:37856434] |
4. Yiren Yang, Yuwei Zhang, Jiangping Song, Yaqian Li, Liuyang Zhou, Hongtao Xu, Kaizhang Wu, Jie Gao, Mouming Zhao, Yang Zheng. (2023) Bergamot polysaccharides relieve DSS-induced ulcerative colitis via regulating the gut microbiota and metabolites. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 253 (1): (127335). [PMID:37820919] |
5. Jing Li, Fangzhou Dou, Shasha Hu, Jianjun Gao. (2023) Involvement of adaptive immune responses in a model of subacute colitis induced with dextran sulfate sodium in C57BL/6 mice. Drug Discoveries and Therapeutics, 17 (4): (294-298). [PMID:37438111] |
6. Jiaojiao Hao, Jinsheng Huang, Chunyu Hua, Yan Zuo, Wendan Yu, Xiaojun Wu, Liren Li, Guoqing Xue, Xinyu Wan, Liyuan Ru, Ziyue Guo, Shilong Han, Wuguo Deng, Fei Lin, Wei Guo. (2023) A novel TOX3-WDR5-ABCG2 signaling axis regulates the progression of colorectal cancer by accelerating stem-like traits and chemoresistance. PLOS BIOLOGY, 21 (9): (e3002256). [PMID:37708089] |
7. Jie Xiong, Jia-jia Yu, Dong-mei Liu, Jia-Juan Wu, Ming-Hua Liang, Jun Tang, Yi-Qian Xu. (2023) A polysaccharide from yogurt fermented by Lactobacillus bulgaricus and Streptococcus thermophilus: Structural characteristics and its alleviative effect on DSS-induced colitis in mice. Journal of Functional Foods, 109 (15): (105778). [PMID:20080952] |
8. Bingqing Zhang, Qiang Li, Qinglin Xu, Baochao Li, Heng Dong, Yongbin Mou. (2023) Polydopamine Modified Ceria Nanorods Alleviate Inflammation in Colitis by Scavenging ROS and Regulating Macrophage M2 Polarization. International Journal of Nanomedicine, [PMID:37600119] |
9. Manxiu Huai, Mingliang Pei, Jiaxing Pan, Yun Zhu, Yingwen Chen, Peng Du, Yanming Duan, Huixiong Xu, Wensong Ge. (2023) Oral colon-targeted responsive alginate/hyaluronic acid-based hydrogel propels the application of infliximab in colitis. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, (125952). [PMID:37494992] |
10. Di Wang, Wenbao Wang, Xue Bing, Chenguang Xu, Jiahua Qiu, Jiangang Shen, Jinwen Huang, Junda Li, Pi Liu, Biao Xie. (2023) GPR35-mediated kynurenic acid sensing contributes to maintenance of gut microbiota homeostasis in ulcerative colitis. FEBS Open Bio, [PMID:37423235] |
11. Yan Yang, Mingyuan Li, Hairui Yu, Yi Tong, Qiqing Chen. (2023) Effects of fibrous microplastics on the accumulation of tris(2,3-dibromopropyl) isocyanurate and behavior of zebrafish via water- and foodborne exposure routes. SCIENCE OF THE TOTAL ENVIRONMENT, 892 (164389). [PMID:37236466] |
12. Zhijie Wen, Li Kang, Hudie Fu, Shengpeng Zhu, Xuexin Ye, Xuedan Yang, Shangwen Zhang, Jie Hu, Xiaojun Li, Lvyi Chen, Yan Hu, Xinzhou Yang. (2023) Oral delivery of porous starch-loaded bilayer microgels for controlled drug delivery and treatment of ulcerative colitis. CARBOHYDRATE POLYMERS, 314 (120887). [PMID:37173037] |
13. Huang Rong, Yao Jiaxu, Zhou Li, Li Xiang, Zhu Jinrui, Hu Yueqi, Liu Jikai. (2023) Protective effect and mechanism insight of purified Antarctic krill phospholipids against mice ulcerative colitis combined with bioinformatics. Natural Products and Bioprospecting, 13 (1): (1-12). [PMID:37016023] |
14. Sili Zheng, Dongning Zhang, Bailu Duan, Guoyan Mo, Jingjing Li, Hailing Huang, Shanshan Wang, Yan Ye, Zhuang Huang, Ping Huang, Fengyun Zhang, Fang Huang, Lintao Han. (2023) Metabolomics integrated network pharmacology reveals the mechanism of Ma-Mu-Ran Antidiarrheal Capsules on acute enteritis mice. ANALYTICAL BIOCHEMISTRY, 668 (115116). [PMID:36925055] |
15. Zirong Li, Biaobiao Yan, Leilei Wu, Bo Xu, Li Cui, Yuanyuan Yu, Ping Wang. (2023) DS-guided deposition of PEDOT onto silk fabrics for rapid photothermal antibacterial and respiratory sensing. COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS, 666 (131285). [PMID:] |
16. Hu Xiaoming, Jiao Fuxin, Deng Jiali, Zhou Ziheng, Chen Shanghai, Liu Changqin, Liu Zhanju, Guo Feifan. (2023) Intestinal Epithelial Cell-specific Deletion of Cytokine-inducible SH2-containing Protein Alleviates Experimental Colitis in Ageing Mice. Journal of Crohns & Colitis, 17 (8): (1278-1290). [PMID:36881790] |
17. Wei Sun, Yingxuan Chen, Liang Wang, Ze Wang, Shuwei Liu, Mengzhu Zhang, Yi Liu, Quanshun Li, Hao Zhang. (2023) Gram-scale preparation of quercetin supramolecular nanoribbons for intestinal inflammatory diseases by oral administration. BIOMATERIALS, 295 (122039). [PMID:36791522] |
18. Caihong Wang, Zihong Pan, Yuanxiang Jin. (2023) F–53B induces hepatotoxic effects and slows self-healing in ulcerative colitis in mice. ENVIRONMENTAL POLLUTION, 317 (120819). [PMID:36481465] |
19. Jinyu An, Xue Jiang, Zhe Wang, Yingqiao Li, Zhiru Zou, Qian Wu, Le Tong, Xifan Mei, He Tian, Chao Wu. (2022) Codelivery of minocycline hydrochloride and dextran sulfate via bionic liposomes for the treatment of spinal cord injury. INTERNATIONAL JOURNAL OF PHARMACEUTICS, 628 (122285). [PMID:36244559] |
20. Jiang Tianze, Xie Laozhi, Zhou Songlei, Liu Yipu, Huang Yukun, Mei Ni, Ma Fenfen, Gong Jingru, Gao Xiaoling, Chen Jun. (2022) Metformin and histone deacetylase inhibitor based anti-inflammatory nanoplatform for epithelial-mesenchymal transition suppression and metastatic tumor treatment. JOURNAL OF NANOBIOTECHNOLOGY, 20 (1): (1-21). [PMID:36045429] |
21. Xiang Li, Shijun Xin, Xiaoqun Zheng, Liqin Lou, Shiqing Ye, Shengkai Li, Qilong Wu, Qingyong Ding, Ling Ji, Chunrong Nan, Yongliang Lou. (2022) Inhibition of the Occurrence and Development of Inflammation-Related Colorectal Cancer by Fucoidan Extracted from Sargassum fusiforme. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 70 (30): (9463–9476). [PMID:35858119] |
22. Huang Yonggang, Wu Miaomiao, Xiao Hao, Liu Hongnan, Yang Guan. (2022) Mesalamine-Mediated Amelioration of Experimental Colitis in Piglets Involves Gut Microbiota Modulation and Intestinal Immune Cell Infiltration. Frontiers in Immunology, 13 [PMID:35898495] |
23. Minghao Zhang, Jinrui Zhu, Li Zhou, Jianquan Kan, Minjie Zhao, Rong Huang, Jikai Liu, Eric Marchioni. (2022) Antarctic krill oil high internal phase Pickering emulsion stabilized by bamboo protein gels and the anti-inflammatory effect in vitro and in vivo. Journal of Functional Foods, 94 (105134). [PMID:] |
24. Jin Liang, Qian Tao, Zhu Tao, Wang Ren-Liang, Chen Wei-Guo, Jiang Hua, Cui Zhi-Hua. (2022) Synthesis, Application, and Recovery of Alkali-Clearable Disperse Dyes Containing Azo Pyridone Structure. FIBERS AND POLYMERS, 23 (4): (1040-1049). [PMID:] |
25. Yuanfang Kong, Yulong Hu, Jieming Li, Juntao Cai, Yuanhao Qiu, Chunhong Dong. (2022) Anti-inflammatory Effect of a Novel Pectin Polysaccharide From Rubus chingii Hu on Colitis Mice. Frontiers in Nutrition, 9 (868657). [PMID:35571944] |
26. Si-Yuan Lu, Yang Liu, Shijie Tang, Wancong Zhang, Qiuyong Yu, Changqi Shi, Kit-Leong Cheong. (2022) Gracilaria lemaneiformis polysaccharides alleviate colitis by modulating the gut microbiota and intestinal barrier in mice. Food Chemistry-X, 13 (100197). [PMID:35498989] |
27. Ping Zhang, Le Su, Feifan Ma, Xiuyu Ji, Yue Su, Qiulin Yue, Chen Zhao, Song Zhang, Xin Sun, Lin Zhao. (2022) Weilan gum oligosaccharide ameliorates dextran sulfate sodium‑induced experimental ulcerative colitis. Molecular Medicine Reports, 25 (2): (1-11). [PMID:34913079] |
28. Jing Yang, Jinzhe Zhou, Yingying Zhao, Liangchen Zhu, Guanghong Luo, BuJun Ge. (2021) Hollow CeO2 with ROS-Scavenging Activity to Alleviate Colitis in Mice. International Journal of Nanomedicine, [PMID:34675513] |
29. Qing Wang,Mao Ye,Li Xu,Zhi-guo Shi. (2015-09-01) A reversed-phase/hydrophilic interaction mixed-mode C18-Diol stationary phase for multiple applications.. Analytica chimica acta, 888 (182-190). [PMID:26320974] |
1. Yi Sun, Cheng Zhang, Yu-ting Yang, Hui Yu, Jing-hong Li. (2023) Polarization-Sensitive Asymmetric Scattering at the Single-Particle Scale via Surface Plasmon Resonance Microscopy. ANALYTICAL CHEMISTRY, 95 (51): (18898–18906). [PMID:38096497] |
2. Yue Wu, Xiaoyu Liang, Canquan Mao, Yuhong Jiang. (2023) The Distinct Properties of Polysaccharide Nanoparticles Tune Immune Responses against mRNA Antigen via Stimulator of Interferon Genes-Mediated Autophagy and Inflammasome. ACS Nano, 17 (21): (21782–21798). [PMID:37922196] |
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