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diABZI-4 , CAS No.D609865, Agonist of stimulator of interferon response cGAMP interactor 1

diABZI-4 , CAS No.D609865, Agonist of stimulator of interferon response cGAMP interactor 1

Item Number

D609865

Grouped product items
SKU	Size	Availability	Price	Qty
D609865-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,400.90
D609865-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$2,000.90

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Basic Description

Specifications & Purity	Moligand™
Grade	Moligand™
Action Type	AGONIST
Mechanism of action	Agonist of stimulator of interferon response cGAMP interactor 1

TMEM173 Tchem Stimulator of interferon genes protein (0 Activities)

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

IUPAC Name	1-[(E)-4-[5-carbamoyl-7-[3-(dimethylamino)propoxy]-2-[(2-ethyl-5-methylpyrazole-3-carbonyl)amino]benzimidazol-1-yl]but-2-enyl]-2-[(2-ethyl-5-methylpyrazole-3-carbonyl)amino]-7-methoxybenzimidazole-5-carboxamide
INCHI	InChI=1S/C40H49N13O6/c1-8-52-29(17-23(3)47-52)37(56)45-39-43-27-19-25(35(41)54)21-31(58-7)33(27)50(39)14-10-11-15-51-34-28(20-26(36(42)55)22-32(34)59-16-12-13-49(5)6)44-40(51)46-38(57)30-18-24(4)48-53(30)9-2/h10-11,17-22H,8-9,12-16H2,1-7H3,(H2,41,54)(H2,42,55)(H,43,45,56)(H,44,46,57)/b11-10+
InChi Key	MXHZAYVEIKSPIA-ZHACJKMWSA-N
Canonical SMILES	COc1cc(cc2c1n(C/C=C/Cn1/c(=N/C(=O)c3cc(nn3CC)C)/[nH]c3c1c(OCCCN(C)C)cc(c3)C(=O)N)/c(=N/C(=O)c1cc(nn1CC)C)/[nH]2)C(=O)N
PubChem CID	132000148

PubChem CID	132000148

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1. Humphries F, Shmuel-Galia L, Jiang Z, Wilson R, Landis P, Ng S-L, Parsi K-M, Maehr R, Cruz J, Morales-Ramos A et al.. (2021) A diamidobenzimidazole STING agonist protects against SARS-CoV-2 infection.. Sci Immunol, 6 (59): (1755-70). [PMID:34010139] [10.1126/sciimmunol.abi9002]

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