Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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D432326-250mg | 250mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $63.90 | |
D432326-1g | 1g | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $229.90 | |
D432326-5g | 5g | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $799.90 | |
D432326-25g | 25g | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $2,399.90 |
Synonyms | Allyl disulfide |
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Specifications & Purity | ≥96% |
Biochemical and Physiological Mechanisms | Organosulfur compound that is naturally found in garlic. Contributes to the pungent odor of crushed garlic. Anticancer agent and may provide protection against cardiovascular disease. Diallyl disulfide has been shown to be an anticancer agent and may prov |
Storage Temp | Store at -20°C,Argon charged |
Shipped In | Ice chest + Ice pads |
Product Description | Diallyl disulfide is an organosulfur compound that is naturally found in garlic ( Allium sativum ) and contributes to the pungent odor of crushed garlic. Application: |
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Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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IUPAC Name | 3-(prop-2-enyldisulfanyl)prop-1-ene |
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INCHI | InChI=1S/C6H10S2/c1-3-5-7-8-6-4-2/h3-4H,1-2,5-6H2 |
InChi Key | PFRGXCVKLLPLIP-UHFFFAOYSA-N |
Canonical SMILES | C=CCSSCC=C |
Isomeric SMILES | C=CCSSCC=C |
WGK Germany | 3 |
RTECS | BB1000000 |
PubChem CID | 16590 |
UN Number | 2810 |
Molecular Weight | 146.27 |
Beilstein | 1699241 |
Reaxy-Rn | 1699241 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
---|---|---|---|
I2418449 | Certificate of Analysis | Aug 10, 2024 | D432326 |
I2418450 | Certificate of Analysis | Aug 10, 2024 | D432326 |
I2418451 | Certificate of Analysis | Aug 10, 2024 | D432326 |
I2418452 | Certificate of Analysis | Aug 10, 2024 | D432326 |
I2418453 | Certificate of Analysis | Aug 10, 2024 | D432326 |
I2418454 | Certificate of Analysis | Aug 10, 2024 | D432326 |
I2418455 | Certificate of Analysis | Aug 10, 2024 | D432326 |
I2418456 | Certificate of Analysis | Aug 10, 2024 | D432326 |
Sensitivity | Air and heat sensitive |
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Refractive Index | 1.561 |
Flash Point(°F) | 143.6 °F |
Flash Point(°C) | 51°C |
Boil Point(°C) | 80-85°C |
Pictogram(s) | GHS06 |
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Signal | Danger |
Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H301:Toxic if swallowed H317:May cause an allergic skin reaction H226:Flammable liquid and vapor |
Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P370+P378:In case of fire: Use ... to extinguish. P210:Keep away from heat, hot surface, sparks, open flames and other ignition sources. - No smoking. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P233:Keep container tightly closed. P240:Ground/bond container and receiving equipment. P264:Wash hands [and …] thoroughly after handling. P403+P235:Store in a well-ventilated place. Keep cool. P303+P361+P353:IF ON SKIN (or hair): Take off Immediately all contaminated clothing. Rinse SKIN with water [or shower]. P241:Use explosion-proof [electrical/ventilating/lighting/.../] equipment. P270:Do not eat, drink or smoke when using this product. P272:Contaminated work clothing should not be allowed out of the workplace. P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P242:Use only non-sparking tools. P243:Take precautionary measures against static discharge. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P316:IF SWALLOWED: Get emergency medical help immediately. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. |
WGK Germany | 3 |
RTECS | BB1000000 |
Reaxy-Rn | 1699241 |
1. Shuaishuai Chen, Weiyu Guo, Huan Liu, Jiang Zheng, Dingyan Lu, Jia Sun, Chun Li, Chunhua Liu, Yonglin Wang, Yong Huang, Wen Liu, Yongjun Li, Ting Liu. (2023) Mechanistic study of cytochrome P450 enzyme-mediated cytotoxicity of psoralen and isopsoralen. FOOD AND CHEMICAL TOXICOLOGY, 180 (28): (114011). [PMID:37660943] [10.1016/j.fct.2023.114011] |
2. Ting Wang, Jing Deng, Ruijin Ran, Wenqiang Shi, Yunxia Gao, Xiang Ren, Jun Cao, Ming Zhang. (2022) In-situ forming PEG-engineering hydrogels with anti-fouling characteristics as an artificial vitreous body. CHEMICAL ENGINEERING JOURNAL, 449 (137486). [PMID:] [10.1016/j.cej.2022.137486] |
3. Tingting Li, Likun Ren, Dangfeng Wang, Minjie Song, Qiuying Li, Jianrong Li. (2020) Effect of allicin and its mechanism of action in purine removal in turbot. JOURNAL OF FOOD SCIENCE, 85 (10): (3562-3569). [PMID:32856309] [10.1111/1750-3841.15394] |
4. Zhang Bin, Zheng Zhenjia, Liu Nan, Liu Pengli, Qiu Zhichang, Qiao Xuguang. (2021) Effect of different combined mechanical and thermal treatments on the quality characteristics of garlic paste. JOURNAL OF FOOD SCIENCE AND TECHNOLOGY-MYSORE, 58 (3): (1061-1071). [PMID:33678889] [10.1007/s13197-020-04620-1] |
5. Wu Tiaodi, Li Lin, Song Guangjie, Ran Miaomiao, Lu Xiaoquan, Liu Xiuhui. (2019) An ultrasensitive electrochemical sensor based on cotton carbon fiber composites for the determination of superoxide anion release from cells. MICROCHIMICA ACTA, 186 (3): (1-9). [PMID:30796529] [10.1007/s00604-019-3304-1] |
6. Liu Xin Chao, Zhou Ligang, Liu Qiyong, Liu Zhi Long. (2015) Laboratory Evaluation of Larvicidal Activity of the Essential oil of Allium tuberosum Roots and its Selected Major Constituent Compounds Against Aedes albopictus (Diptera: Culicidae). JOURNAL OF MEDICAL ENTOMOLOGY, 52 (3): (437-441). [PMID:26334818] [10.1093/jme/tjv016] |
1. Jaehoon Bae,Motofumi Kumazoe,Yoshinori Fujimura,Hirofumi Tachibana. (2018-12-06) Diallyl disulfide potentiates anti-obesity effect of green tea in high-fat/high-sucrose diet-induced obesity.. The Journal of nutritional biochemistry, 64 (152-161). [PMID:30504007] |
2. Jie Yang,Paul Minkler,David Grove,Rui Wang,Belinda Willard,Raed Dweik,Christopher Hine. (2019-05-28) Non-enzymatic hydrogen sulfide production from cysteine in blood is catalyzed by iron and vitamin B6.. Communications biology, 2 (194-194). [PMID:31123718] |
3. You Jeong Lee,Song-Hyun Cha,Hyunjo Kim,Sung Eun Choi,Seonho Cho,Youmie Park. (2020-06-05) Diallyl disulphide-loaded spherical gold nanoparticles and acorn-like silver nanoparticles synthesised using onion extract: catalytic activity and cytotoxicity.. Artificial cells, nanomedicine, and biotechnology, 48 ((1)): (948-960). [PMID:32496831] |
4. Venugopal R Bovilla,Mahadevaswamy G Kuruburu,Vidya G Bettada,Jayashree Krishnamurthy,Olga A Sukocheva,Rajesh K Thimmulappa,Nanjunda Swamy Shivananju,Janardhan P Balakrishna,SubbaRao V Madhunapantula. (2021-09-29) Targeted Inhibition of Anti-Inflammatory Regulator Nrf2 Results in Breast Cancer Retardation In Vitro and In Vivo.. Biomedicines, 9 ((9)): [PMID:34572304] |
5. V Robert,B Mouillé,C Mayeur,M Michaud,F Blachier. (2001-07-27) Effects of the garlic compound diallyl disulfide on the metabolism, adherence and cell cycle of HT-29 colon carcinoma cells: evidence of sensitive and resistant sub-populations.. Carcinogenesis, 22 ((8)): (1155-1161). [PMID:11470743] |
6. Lan Yi,Qi Su. (2013-04-16) Molecular mechanisms for the anti-cancer effects of diallyl disulfide.. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 57 (362-370). [PMID:23583486] |
7. Anna Choromanska,Julita Kulbacka,Jolanta Saczko,Pawel Surowiak. (2020-08-18) Effect of diallyl disulfide and garlic oil on different human astrocytoma cell lines.. Biomedical reports, 13 ((4)): (32-32). [PMID:32802329] |
8. Xiuxiu Song,Ziqi Yue,Lulingxiao Nie,Pengfei Zhao,Kangjian Zhu,Qi Wang. (2021-11-09) Biological Functions of Diallyl Disulfide, a Garlic-Derived Natural Organic Sulfur Compound.. Evidence-based complementary and alternative medicine : eCAM, 2021 (5103626-5103626). [PMID:34745287] |
9. Shuaishuai Chen, Weiyu Guo, Huan Liu, Jiang Zheng, Dingyan Lu, Jia Sun, Chun Li, Chunhua Liu, Yonglin Wang, Yong Huang, Wen Liu, Yongjun Li, Ting Liu. (2023) Mechanistic study of cytochrome P450 enzyme-mediated cytotoxicity of psoralen and isopsoralen. FOOD AND CHEMICAL TOXICOLOGY, 180 (28): (114011). [PMID:37660943] [10.1016/j.fct.2023.114011] |
10. Ting Wang, Jing Deng, Ruijin Ran, Wenqiang Shi, Yunxia Gao, Xiang Ren, Jun Cao, Ming Zhang. (2022) In-situ forming PEG-engineering hydrogels with anti-fouling characteristics as an artificial vitreous body. CHEMICAL ENGINEERING JOURNAL, 449 (137486). [PMID:] [10.1016/j.cej.2022.137486] |
11. Tingting Li, Likun Ren, Dangfeng Wang, Minjie Song, Qiuying Li, Jianrong Li. (2020) Effect of allicin and its mechanism of action in purine removal in turbot. JOURNAL OF FOOD SCIENCE, 85 (10): (3562-3569). [PMID:32856309] [10.1111/1750-3841.15394] |
12. Zhang Bin, Zheng Zhenjia, Liu Nan, Liu Pengli, Qiu Zhichang, Qiao Xuguang. (2021) Effect of different combined mechanical and thermal treatments on the quality characteristics of garlic paste. JOURNAL OF FOOD SCIENCE AND TECHNOLOGY-MYSORE, 58 (3): (1061-1071). [PMID:33678889] [10.1007/s13197-020-04620-1] |
13. Wu Tiaodi, Li Lin, Song Guangjie, Ran Miaomiao, Lu Xiaoquan, Liu Xiuhui. (2019) An ultrasensitive electrochemical sensor based on cotton carbon fiber composites for the determination of superoxide anion release from cells. MICROCHIMICA ACTA, 186 (3): (1-9). [PMID:30796529] [10.1007/s00604-019-3304-1] |
14. Liu Xin Chao, Zhou Ligang, Liu Qiyong, Liu Zhi Long. (2015) Laboratory Evaluation of Larvicidal Activity of the Essential oil of Allium tuberosum Roots and its Selected Major Constituent Compounds Against Aedes albopictus (Diptera: Culicidae). JOURNAL OF MEDICAL ENTOMOLOGY, 52 (3): (437-441). [PMID:26334818] [10.1093/jme/tjv016] |