Diallyl tetrasulfide - ≥90%, high purity , CAS No.2444-49-7

  • ≥90%
Item Number
D274966
Grouped product items
SKUSizeAvailabilityPrice Qty
D274966-5mg
5mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$299.90
D274966-25mg
25mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$1,099.90

JNK activator. ROS inducer.

View related series
ROS inducer

Basic Description

SynonymsD274966
Specifications & Purity≥90%
Biochemical and Physiological MechanismsJNK activator. ROS inducer. Irreversible Cdc25 isoforms A and C inhibitor. Targets tubulin. Induces G2-M arrest and apoptosis. Shows antiproliferative, cytoprotective and antioxidant effects in vivo. Orally active.
Storage TempStore at -20°C,Desiccated
Shipped InIce chest + Ice pads
NoteWherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description

Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.


Application

Diallyl Tetrasulfide is a mitotic inhibitor and apoptosis inducers. An anti-carcinogenic agent.Also, it is derived from Allyl Bromide (A549655), which is used as a reagent in the synthesis of Resveratrol derivatives. Resveratrol (R150000) is a minor constitutent of wine, correlated with serum lipid reduction and inhibition of platelet aggregation. Resveratrol is a specific inhibitor of COX-1, and it also inhibits the hydroperoxidase activity of COX-1. It has been shown to inhibit events associated with tumor initiation, promotion and progression.

Associated Targets(Human)

HBB Tbio Hemoglobin subunit beta (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
HCT-116 (91556 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HBA1 Tclin Hemoglobin HbA (880 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Names and Identifiers

IUPAC Name 3-(prop-2-enyltetrasulfanyl)prop-1-ene
INCHI InChI=1S/C6H10S4/c1-3-5-7-9-10-8-6-4-2/h3-4H,1-2,5-6H2
InChi Key RMKCQUWJDRTEHE-UHFFFAOYSA-N
Canonical SMILES C=CCSSSSCC=C
Isomeric SMILES C=CCSSSSCC=C
PubChem CID 75552
Molecular Weight 210.4

Certificates

Certificate of Analysis(COA)

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To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

8 results found

Lot NumberCertificate TypeDateItem
F2417285Certificate of AnalysisJun 05, 2024 D274966
F2417292Certificate of AnalysisJun 05, 2024 D274966
G2322731Certificate of AnalysisMay 21, 2024 D274966
G2322736Certificate of AnalysisJul 13, 2023 D274966
G2322737Certificate of AnalysisJul 13, 2023 D274966
G2322740Certificate of AnalysisJul 13, 2023 D274966
A2212502Certificate of AnalysisDec 29, 2021 D274966
A2212503Certificate of AnalysisDec 29, 2021 D274966

Chemical and Physical Properties

SolubilitySoluble in ethanol to 10 mM and in DMSO to 10 mM

Safety and Hazards(GHS)

Pictogram(s) GHS07
Signal Warning
Hazard Statements

H302:Harmful if swallowed

Precautionary Statements

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P270:Do not eat, drink or smoke when using this product.

P330:Rinse mouth.

P301+P317:IF SWALLOWED: Get medical help.

Related Documents

References

1. Dong H et al..  (2019)  Role of FOXO3 Activated by HIV-1 Tat in HIV-Associated Neurocognitive Disorder Neuronal Apoptosis..  Front Neurosci,  13  (44).  [PMID:30778283]

Solution Calculators