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Diamide - 97%（HPLC）, high purity , CAS No.10465-78-8
Basic Description Synonyms TMAD | (+/-)-Secobarbital | Azodicarboxylic acid bis-dimethylamide | TMAD | 1,N-dimethylformamide) | BP-10037 | FT-0642495 | N,N',N'-Tetramethylazobisformamide | CCG-204490 | CHEBI:6863 | NSC 143013 | NCGC00093824-02 | GTPL7505 | N,N,N',N'-Tetramethylazod Specifications & Purity ≥97%(HPLC) Storage Temp Store at -20°C,Argon charged Shipped In Ice chest + Ice pads Product Description Reported to be of use as a thiol oxidizing agent. Diamide has been used to titrate protein glutathiolation to discriminate from other oxidative protein modifications. Treatment increased protein glutathiolation in a concentration-dependent manner and had comparably little effect on protein-protein disulfide formation.
Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References
Names and Identifiers IUPAC Name (3E)-3-(dimethylcarbamoylimino)-1,1-dimethylurea INCHI InChI=1S/C6H12N4O2/c1-9(2)5(11)7-8-6(12)10(3)4/h1-4H3/b8-7+ InChi Key VLSDXINSOMDCBK-BQYQJAHWSA-N Canonical SMILES CN(C)C(=O)N=NC(=O)N(C)C Isomeric SMILES CN(C)C(=O)/N=N/C(=O)N(C)C WGK Germany 3 RTECS LQ1041000 PubChem CID 5353800 Molecular Weight 172.19 Beilstein 1910410
Chemical and Physical Properties Solubility water: 19.60-21.00 mg/mL, clear to slightly hazy, orange Sensitivity air sensitive；heat sensitive Melt Point(°C) 113-115 °C
Safety and Hazards(GHS) Pictogram(s) GHS07 Signal Warning Hazard Statements H315: Causes skin irritation
H319: Causes serious eye irritation
H335: May cause respiratory irritation
Precautionary Statements P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352: IF ON SKIN: wash with plenty of water.
P321: Specific treatment (see ... on this label).
P405: Store locked up.
P501: Dispose of contents/container to ...
P264: Wash hands [and …] thoroughly after handling.
P271: Use only outdoors or in a well-ventilated area.
P304+P340: IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P403+P233: Store in a well-ventilated place. Keep container tightly closed.
P362+P364: Take off contaminated clothing and wash it before reuse.
P264+P265: Wash hands [and …] thoroughly after handling. Do not touch eyes.
P337+P317: If eye irritation persists: Get medical help.
P332+P317: If skin irritation occurs: Get medical help.
P319: Get medical help if you feel unwell.
WGK Germany 3 RTECS LQ1041000
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