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Diazoxide - ≥98%, high purity , CAS No.364-98-7, Activator of K ir6.1;Activator of K ir6.2

Moligand™
≥98%

CAS#: 364-98-7
Formula: C₈H₇ClN₂O₂S
Molecular Weight: 230.67
EC Number: 206-668-1
MDL number: MFCD00078578
PubChem CID: 3019
PubChem SID: 488179733

Item Number

D136582

Grouped product items
SKU	Size	Availability	Price
D136582-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$17.90
D136582-250mg	250mg	In stock	$66.90
D136582-1g	1g	In stock	$190.90
D136582-5g	5g	In stock	$859.90

Selective K IR 6.x (ATP-sensitive K + channel) activator

View related series

Kir6.1 Activator Kir6.2 Activator

Basic Description

Synonyms	diazoxide\|364-98-7\|Proglycem\|Hyperstat\|Hypertonalum\|Eudemine\|Proglicem\|Dizoxide\|Mutabase\|7-Chloro-3-methyl-2H-1,2,4-benzothiadiazine 1,1-dioxide\|Diazossido\|Diazoxidum\|Sch 6783\|Sch-6783\|Diazoxido\|SRG 95213\|SRG-95213\|C8H7ClN2O2S\|Eudemine injection\|2H-1,2,4-
Specifications & Purity	≥98%
Storage Temp	Store at 2-8°C
Shipped In	Wet ice
Grade	Moligand™
Action Type	ACTIVATOR
Mechanism of action	Activator of K ir6.1;Activator of K ir6.2

Associated Targets

KCNJ8 Tbio ATP-sensitive inward rectifier potassium channel 8 0 Activities

Discover Target: KCNJ8

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

KCNJ11 Tclin ATP-sensitive inward rectifier potassium channel 11 1 Activities

Discover Target: KCNJ11

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

Pubchem Sid	488179733
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/488179733
IUPAC Name	7-chloro-3-methyl-4H-1λ6,2,4-benzothiadiazine 1,1-dioxide
INCHI	InChI=1S/C8H7ClN2O2S/c1-5-10-7-3-2-6(9)4-8(7)14(12,13)11-5/h2-4H,1H3,(H,10,11)
InChi Key	GDLBFKVLRPITMI-UHFFFAOYSA-N
Canonical SMILES	CC1=NS(=O)(=O)C2=C(N1)C=CC(=C2)Cl
Isomeric SMILES	CC1=NS(=O)(=O)C2=C(N1)C=CC(=C2)Cl
WGK Germany	3
RTECS	DK8185000
PubChem CID	3019
Molecular Weight	230.67

PubChem CID

DrugBank Ligand

CAS Registry No.

ChEBI

Wikipedia

ChEMBL Ligand

BindingDB Ligand

RCSB PDB Ligand

DrugCentral Ligand

PubChem SID

Certificates

Certificate of Analysis(COA)

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13 results found

Lot Number	Certificate Type	Date	Item
C2218236	Certificate of Analysis	Jan 04, 2024	D136582
C2425056	Certificate of Analysis	Aug 15, 2023	D136582
H2328633	Certificate of Analysis	Aug 15, 2023	D136582
H2328678	Certificate of Analysis	Aug 15, 2023	D136582
H2328711	Certificate of Analysis	Aug 15, 2023	D136582
C1927101	Certificate of Analysis	Nov 18, 2022	D136582
B2303299	Certificate of Analysis	Oct 29, 2022	D136582
B2303300	Certificate of Analysis	Oct 29, 2022	D136582
B2303301	Certificate of Analysis	Oct 29, 2022	D136582
B2303302	Certificate of Analysis	Oct 29, 2022	D136582
B2303303	Certificate of Analysis	Oct 29, 2022	D136582
C2218185	Certificate of Analysis	Feb 09, 2022	D136582
C2218211	Certificate of Analysis	Feb 09, 2022	D136582

Solubility

Insoluble in water; Soluble in Dimethylformamide,Alcohol

Sensitivity

Heat sensitive

Melt Point(°C)

332 °C

Safety and Hazards(GHS)

Pictogram(s)	GHS08, GHS07
Signal	Danger
Hazard Statements	H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation H302:Harmful if swallowed H372:Causes damage to organs through prolonged or repeated exposure H360:May damage fertility or the unborn child
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P260:Do not breathe dust/fume/gas/mist/vapors/spray. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P203:Obtain, read and follow all safety instructions before use. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P317:IF SWALLOWED: Get medical help. P318:if exposed or concerned, get medical advice. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell.
WGK Germany	3
RTECS	DK8185000
Merck Index	3004

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