Diazoxide - ≥98%, high purity , CAS No.364-98-7, Activator of K ir6.1;Activator of K ir6.2

Item Number
D136582
Grouped product items
SKUSizeAvailabilityPrice Qty
D136582-50mg
50mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$17.90
D136582-250mg
250mg
In stock
$66.90
D136582-1g
1g
In stock
$190.90
D136582-5g
5g
In stock
$859.90

Selective K IR 6.x (ATP-sensitive K + channel) activator

View related series
Kir6.1 Activator Kir6.2 Activator

Basic Description

SynonymsMFCD00078578 | Diazoxido | EINECS 206-668-1 | SMR000058392 | 7-Chloro-3-methyl-2H-1,4-benzothiadiazine 1,1-dioxide | DTXCID902914 | 7-chloro-3-methyl-4H-1$l^{6},2,4-benzothiadiazine 1,1-dioxide | Bio1_000036 | DIAZOXIDE [EP MONOGRAPH] | Diazoxidum | NSC76
Specifications & PurityMoligand™, ≥98%
Biochemical and Physiological MechanismsSelective K IR 6.x (K ATP ) activator; antihypertensive.
Storage TempStore at 2-8°C
Shipped InWet ice
GradeMoligand™
Action TypeACTIVATOR
Mechanism of actionActivator of K ir6.1;Activator of K ir6.2
NoteWherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Associated Targets(Human)

KCNJ8 Tbio ATP-sensitive inward rectifier potassium channel 8 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
KCNJ11 Tclin ATP-sensitive inward rectifier potassium channel 11 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

Pubchem Sid488179733
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488179733
IUPAC Name 7-chloro-3-methyl-4H-1λ6,2,4-benzothiadiazine 1,1-dioxide
INCHI InChI=1S/C8H7ClN2O2S/c1-5-10-7-3-2-6(9)4-8(7)14(12,13)11-5/h2-4H,1H3,(H,10,11)
InChi Key GDLBFKVLRPITMI-UHFFFAOYSA-N
Canonical SMILES CC1=NS(=O)(=O)C2=C(N1)C=CC(=C2)Cl
Isomeric SMILES CC1=NS(=O)(=O)C2=C(N1)C=CC(=C2)Cl
WGK Germany 3
RTECS DK8185000
PubChem CID 3019
Molecular Weight 230.67

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

13 results found

Lot NumberCertificate TypeDateItem
C2218236Certificate of AnalysisJan 04, 2024 D136582
C2425056Certificate of AnalysisAug 15, 2023 D136582
H2328633Certificate of AnalysisAug 15, 2023 D136582
H2328678Certificate of AnalysisAug 15, 2023 D136582
H2328711Certificate of AnalysisAug 15, 2023 D136582
C1927101Certificate of AnalysisNov 18, 2022 D136582
B2303299Certificate of AnalysisOct 29, 2022 D136582
B2303300Certificate of AnalysisOct 29, 2022 D136582
B2303301Certificate of AnalysisOct 29, 2022 D136582
B2303302Certificate of AnalysisOct 29, 2022 D136582
B2303303Certificate of AnalysisOct 29, 2022 D136582
C2218185Certificate of AnalysisFeb 09, 2022 D136582
C2218211Certificate of AnalysisFeb 09, 2022 D136582

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Chemical and Physical Properties

SolubilityInsoluble in water; Soluble in Dimethylformamide,Alcohol
SensitivityHeat sensitive
Melt Point(°C)332 °C

Safety and Hazards(GHS)

Pictogram(s) GHS08,   GHS07
Signal Danger
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

H335:May cause respiratory irritation

H302:Harmful if swallowed

H372:Causes damage to organs through prolonged or repeated exposure

H360:May damage fertility or the unborn child

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P260:Do not breathe dust/fume/gas/mist/vapors/spray.

P271:Use only outdoors or in a well-ventilated area.

P270:Do not eat, drink or smoke when using this product.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P403+P233:Store in a well-ventilated place. Keep container tightly closed.

P362+P364:Take off contaminated clothing and wash it before reuse.

P330:Rinse mouth.

P203:Obtain, read and follow all safety instructions before use.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P301+P317:IF SWALLOWED: Get medical help.

P318:if exposed or concerned, get medical advice.

P337+P317:If eye irritation persists: Get medical help.

P332+P317:If skin irritation occurs: Get medical help.

P319:Get medical help if you feel unwell.

WGK Germany 3
RTECS DK8185000
Merck Index 3004

Related Documents

Solution Calculators