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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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D136582-50mg | 50mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $17.90 | |
D136582-250mg | 250mg | In stock | $66.90 | |
D136582-1g | 1g | In stock | $190.90 | |
D136582-5g | 5g | In stock | $859.90 |
Selective K IR 6.x (ATP-sensitive K + channel) activator
Synonyms | MFCD00078578 | Diazoxido | EINECS 206-668-1 | SMR000058392 | 7-Chloro-3-methyl-2H-1,4-benzothiadiazine 1,1-dioxide | DTXCID902914 | 7-chloro-3-methyl-4H-1$l^{6},2,4-benzothiadiazine 1,1-dioxide | Bio1_000036 | DIAZOXIDE [EP MONOGRAPH] | Diazoxidum | NSC76 |
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Specifications & Purity | Moligand™, ≥98% |
Biochemical and Physiological Mechanisms | Selective K IR 6.x (K ATP ) activator; antihypertensive. |
Storage Temp | Store at 2-8°C |
Shipped In | Wet ice |
Grade | Moligand™ |
Action Type | ACTIVATOR |
Mechanism of action | Activator of K ir6.1;Activator of K ir6.2 |
Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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Pubchem Sid | 488179733 |
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Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/488179733 |
IUPAC Name | 7-chloro-3-methyl-4H-1λ6,2,4-benzothiadiazine 1,1-dioxide |
INCHI | InChI=1S/C8H7ClN2O2S/c1-5-10-7-3-2-6(9)4-8(7)14(12,13)11-5/h2-4H,1H3,(H,10,11) |
InChi Key | GDLBFKVLRPITMI-UHFFFAOYSA-N |
Canonical SMILES | CC1=NS(=O)(=O)C2=C(N1)C=CC(=C2)Cl |
Isomeric SMILES | CC1=NS(=O)(=O)C2=C(N1)C=CC(=C2)Cl |
WGK Germany | 3 |
RTECS | DK8185000 |
PubChem CID | 3019 |
Molecular Weight | 230.67 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
---|---|---|---|
B2303299 | Certificate of Analysis | Nov 18, 2024 | D136582 |
B2303301 | Certificate of Analysis | Nov 18, 2024 | D136582 |
B2303303 | Certificate of Analysis | Nov 18, 2024 | D136582 |
B2303302 | Certificate of Analysis | Nov 07, 2024 | D136582 |
B2303300 | Certificate of Analysis | Nov 07, 2024 | D136582 |
C2218236 | Certificate of Analysis | Jan 04, 2024 | D136582 |
C2425056 | Certificate of Analysis | Aug 15, 2023 | D136582 |
H2328633 | Certificate of Analysis | Aug 15, 2023 | D136582 |
H2328678 | Certificate of Analysis | Aug 15, 2023 | D136582 |
H2328711 | Certificate of Analysis | Aug 15, 2023 | D136582 |
C1927101 | Certificate of Analysis | Nov 18, 2022 | D136582 |
C2218185 | Certificate of Analysis | Feb 09, 2022 | D136582 |
C2218211 | Certificate of Analysis | Feb 09, 2022 | D136582 |
Solubility | Insoluble in water; Soluble in Dimethylformamide,Alcohol |
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Sensitivity | Heat sensitive |
Melt Point(°C) | 332 °C |
Pictogram(s) | GHS08, GHS07 |
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Signal | Danger |
Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation H302:Harmful if swallowed H372:Causes damage to organs through prolonged or repeated exposure H360:May damage fertility or the unborn child |
Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P260:Do not breathe dust/fume/gas/mist/vapors/spray. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P203:Obtain, read and follow all safety instructions before use. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P317:IF SWALLOWED: Get medical help. P318:if exposed or concerned, get medical advice. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell. |
WGK Germany | 3 |
RTECS | DK8185000 |
Merck Index | 3004 |