Diclofenac - >98.0%, high purity , Cyclooxygenase inhibitor, CAS No.15307-86-5, Cyclooxygenase inhibitor

29 Citations
Item Number
D155733
Grouped product items
SKUSizeAvailabilityPrice Qty
D155733-1g
1g
In stock
$14.90
D155733-5g
5g
In stock
$60.90
D155733-25g
25g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$274.90
D155733-100g
100g
In stock
$988.90
D155733-500g
500g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$4,446.90

Basic Description

Synonymsdiclofenac | Diclofenac acid | 15307-86-5 | dichlofenac | Diclofenacum | Diclophenac | Diclofenaco | ProSorb-D | 2-(2-((2,6-Dichlorophenyl)amino)phenyl)acetic acid | Diclofenac resinate | Voltarol | Diclofenac free acid | 2-(2,6-Dichloroanilino)phenylacetic Acid | Zorovolex | Zorvol
Specifications & PurityMoligand™, ≥98%
Storage TempStore at 2-8°C
Shipped InWet ice
GradeMoligand™
Action TypeAGONIST, ANTAGONIST, CHANNEL BLOCKER, INHIBITOR
Mechanism of actionCyclooxygenase inhibitor
Product Description

Diclofenac is a non-selective COX inhibitor with IC50 of 60 and 220 nM for ovine COX-1 and -2, respectively. Target: COX Diclofenac is a nonsteroidal anti-inflammatory drug (NSAID) taken or applied to reduce inflammation and as an analgesic reducing pain in certain conditions. The primary mechanism responsible for its anti-inflammatory, antipyretic, and analgesic action is thought to be inhibition of prostaglandin synthesis by inhibition of cyclooxygenase (COX). It also appears to exhibit bacteriostatic activity by inhibiting bacterial DNA synthesis. Inhibition of COX also decreases prostaglandins in the epithelium of the stomach, making it more sensitive to corrosion by gastric acid. This is also the main side effect of diclofenac. Diclofenac has a low to moderate preference to block the COX2-isoenzyme and is said to have, therefore, a somewhat lower incidence of gastrointestinal complaints than noted with indomethacin and aspirin.

Diclofenac acid is a nonsteroidal anti-inflammatory compound and decycloxygenase (COX) inhibitor.

Associated Targets(Human)

CXCR1 Tchem C-X-C chemokine receptor type 1 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
TRPM3 Tchem Transient receptor potential cation channel subfamily M member 3 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
TTR Tclin Transthyretin (2 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
PTGS1 Tclin Prostaglandin G/H synthase 1 (10 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
PTGS2 Tclin Prostaglandin G/H synthase 2 (15 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ASIC3 Tchem Acid-sensing ion channel 3 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
PPARG Tclin Peroxisome proliferator-activated receptor gamma (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CXCL8 Tchem Interleukin-8 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
PDE5A Tclin Phosphodiesterase 5A (5113 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DHFR Tclin Dihydrofolate reductase (3072 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ABL1 Tclin Tyrosine-protein kinase ABL (18331 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
EGFR Tclin Epidermal growth factor receptor erbB1 (33727 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
F2 Tclin Thrombin (11687 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CA2 Tclin Carbonic anhydrase II (17698 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ESR1 Tclin Estrogen receptor alpha (17718 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HMGCR Tclin HMG-CoA reductase (2475 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
NR3C1 Tclin Glucocorticoid receptor (14987 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
INSR Tclin Insulin receptor (5558 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PGR Tclin Progesterone receptor (8562 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRB2 Tclin Beta-2 adrenergic receptor (11824 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CHRM2 Tclin Muscarinic acetylcholine receptor M2 (10671 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRB1 Tclin Beta-1 adrenergic receptor (6630 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HTR1A Tclin Serotonin 1a (5-HT1a) receptor (14969 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRA2A Tclin Alpha-2a adrenergic receptor (9450 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
AR Tclin Androgen Receptor (11781 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
RARA Tclin Retinoic acid receptor alpha (1324 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CHRM1 Tclin Muscarinic acetylcholine receptor M1 (12690 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ACE Tclin Angiotensin-converting enzyme (1423 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DRD2 Tclin Dopamine D2 receptor (23596 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GABRA1 Tclin GABA receptor alpha-1 subunit (399 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MAOA Tclin Monoamine oxidase A (11911 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CNR1 Tclin Cannabinoid CB1 receptor (20913 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DRD1 Tclin Dopamine D1 receptor (9720 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DRD4 Tchem Dopamine D4 receptor (7907 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ACHE Tclin Acetylcholinesterase (18204 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PTGS1 Tclin Cyclooxygenase-1 (9233 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLC6A2 Tclin Norepinephrine transporter (10102 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HRH2 Tclin Histamine H2 receptor (5428 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRA1D Tclin Alpha-1d adrenergic receptor (4171 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HTR1B Tclin Serotonin 1b (5-HT1b) receptor (2801 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HTR2A Tclin Serotonin 2a (5-HT2a) receptor (14758 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HTR2C Tclin Serotonin 2c (5-HT2c) receptor (11471 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
AVPR2 Tclin Vasopressin V2 receptor (2912 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADORA1 Tclin Adenosine A1 receptor (17603 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
AGTR1 Tclin Type-1 angiotensin II receptor (5176 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CALCR Tclin Calcitonin receptor (2215 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLC6A4 Tclin Serotonin transporter (12625 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CRHR1 Tclin Corticotropin releasing factor receptor 1 (2996 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRA1A Tclin Alpha-1a adrenergic receptor (8359 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PTGS2 Tclin Cyclooxygenase-2 (13999 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HRH1 Tclin Histamine H1 receptor (7573 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ADRA1B Tclin Alpha-1b adrenergic receptor (2912 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
OPRM1 Tclin Mu opioid receptor (19785 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
DRD3 Tclin Dopamine D3 receptor (14368 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PPARG Tclin Peroxisome proliferator-activated receptor gamma (15191 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
AVPR1A Tclin Vasopressin V1a receptor (5412 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
OPRD1 Tclin Delta opioid receptor (15096 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
OPRK1 Tclin Kappa opioid receptor (16155 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Htr7 Serotonin 7 (5-HT7) receptor (19 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Agtr2 Angiotensin II type 2 (AT-2) receptor (803 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mc4r Melanocortin receptor 4 (1205 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Ltc4s Leukotriene C4 synthase (1 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Fdft1 Squalene synthetase (34 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Sigmar1 Sigma opioid receptor (160 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Ttr Transthyretin (14 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Npy1r Neuropeptide Y receptor type 1 (8 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Cckar Cholecystokinin A receptor (90 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Ntsr1 Neurotensin receptor 1 (48 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Pde4d Phosphodiesterase 4D (4 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Bdkrb1 Bradykinin B1 receptor (77 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Aplnr Apelin receptor (201 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Abcc1 Multidrug resistance-associated protein 1 (42 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Abcb1b P-glycoprotein 1 (174 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CA4 Carbonic anhydrase IV (1713 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Nos2 Nitric oxide synthase, inducible (3573 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mapk1 MAP kinase ERK2 (650 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Hdac6 Histone deacetylase 6 (222 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PDE6A Phosphodiesterase 6A (40 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mmp9 Matrix metalloproteinase 9 (38 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Fgfr3 Fibroblast growth factor receptor 3 (21 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Staphylococcus aureus (210822 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Pneumocystis carinii (749 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Leishmania infantum (5912 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Trypanosoma brucei (78846 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Trypanosoma brucei brucei (13300 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Entamoeba histolytica (2676 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Cryptosporidium parvum (1150 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Plasmodium falciparum (966862 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Leishmania amazonensis (3813 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Leishmania donovani (89745 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Leishmania major (2877 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Leishmania mexicana (936 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Trypanosoma cruzi (99888 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Trichomonas vaginalis (2376 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Toxoplasma gondii (4585 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Cavia porcellus (23802 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Oryctolagus cuniculus (11301 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mus musculus (284745 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Rattus norvegicus (775804 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Trypanosoma brucei rhodesiense (7991 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MDCK (10148 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PC-12 (7051 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
RAW264.7 (28094 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
H4 (48 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
L1.2 (32 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Trpa1 Transient receptor potential cation channel subfamily A member 1 (1003 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Gpr119 Glucose-dependent insulinotropic receptor (270 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Names and Identifiers

IUPAC Name 2-[2-(2,6-dichloroanilino)phenyl]acetic acid
INCHI InChI=1S/C14H11Cl2NO2/c15-10-5-3-6-11(16)14(10)17-12-7-2-1-4-9(12)8-13(18)19/h1-7,17H,8H2,(H,18,19)
InChi Key DCOPUUMXTXDBNB-UHFFFAOYSA-N
Canonical SMILES C1=CC=C(C(=C1)CC(=O)O)NC2=C(C=CC=C2Cl)Cl
Isomeric SMILES C1=CC=C(C(=C1)CC(=O)O)NC2=C(C=CC=C2Cl)Cl
RTECS AG6310000
PubChem CID 3033
Molecular Weight 296.15
Reaxy-Rn 2146636

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

13 results found

Lot NumberCertificate TypeDateItem
D2418443Certificate of AnalysisMar 23, 2024 D155733
D2418446Certificate of AnalysisMar 23, 2024 D155733
D2418449Certificate of AnalysisMar 23, 2024 D155733
C2027110Certificate of AnalysisMar 14, 2024 D155733
C2320434Certificate of AnalysisMar 20, 2022 D155733
C2331014Certificate of AnalysisMar 20, 2022 D155733
D2412059Certificate of AnalysisMar 20, 2022 D155733
F2208050Certificate of AnalysisMar 20, 2022 D155733
F2208051Certificate of AnalysisMar 20, 2022 D155733
F2208052Certificate of AnalysisMar 20, 2022 D155733
F2208054Certificate of AnalysisMar 20, 2022 D155733
F2208351Certificate of AnalysisMar 20, 2022 D155733
K2315094Certificate of AnalysisMar 20, 2022 D155733

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Chemical and Physical Properties

SolubilityChloroform (Slightly, Heated), Methanol (Slightly)
Melt Point(°C)158°C

Safety and Hazards(GHS)

Pictogram(s) GHS06,   GHS08,   GHS09
Signal Danger
Hazard Statements

H301:Toxic if swallowed

H411:Toxic to aquatic life with long lasting effects

H372:Causes damage to organs through prolonged or repeated exposure

H361:Suspected of damaging fertility or the unborn child

Precautionary Statements

P273:Avoid release to the environment.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P264:Wash hands [and …] thoroughly after handling.

P260:Do not breathe dust/fume/gas/mist/vapors/spray.

P201:Obtain special instructions before use.

P308+P313:IF exposed or concerned: Get medical advice/attention.

P270:Do not eat, drink or smoke when using this product.

P391:Collect spillage.

P202:Do not handle until all safety precautions have been read and understood.

P301+P310+P330:IF SWALLOWED: Rinse mouth.Immediately call a POISON CENTER/doctor/.

RTECS AG6310000
Reaxy-Rn 2146636
Merck Index 3081

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2. Lianxu Wang, Zhen Lei, Sining Yun, Xiaohuan Yang, Rong Chen.  (2024)  Quantitative structure-biotransformation relationships of organic micropollutants in aerobic and anaerobic wastewater treatments.  SCIENCE OF THE TOTAL ENVIRONMENT,  912  (169170).  [PMID:38072270]
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4. Huan Zhan, Xiaoyan Liu, Jinbing Huang, Xian Liu, Xulong Zhang, Jiaxiong Yao, Shiwei Xie.  (2023)  Iron electrocoagulation activated peracetic acid for efficient degradation of sulfamethoxazole.  CHEMICAL ENGINEERING RESEARCH & DESIGN,  200  (15): (244).  [PMID:1906403]
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19. Xin Liu, Peng Xu, Zhuoyu Yang, Pengfei Zhu, Lei Wang, Shiqi Xie.  (2022)  Catalytic oxidation of 4-acetamidophenol with Fe3+-enhanced Cu0 particles: In-site generation and activation of hydrogen peroxide.  JOURNAL OF HAZARDOUS MATERIALS,  436  (129291).  [PMID:35739796]
20. Peng Xu, Shiqi Xie, Xin Liu, Lei Wang, Xiangwen Jia, Chao Yang.  (2022)  Electrochemical enhanced heterogenous activation of peroxymonosulfate using CuFe2O4 particle electrodes for the degradation of diclofenac.  CHEMICAL ENGINEERING JOURNAL,  446  (136941).  [PMID:]
21. Nkoom Matthew, Lu Guanghua, Liu Jianchao.  (2022)  Chronic toxicity of diclofenac, carbamazepine and their mixture to Daphnia magna: a comparative two-generational study.  ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH,  29  (39): (58963-58979).  [PMID:35378650]
22. Ruifeng Liang, Wenjing Ge, Bingjie Li, Weifeng Cui, Xiaofan Ma, Yuying Pan, Gengsheng Li.  (2022)  Evodiamine decreased the systemic exposure of pravastatin in non-alcoholic steatohepatitis rats due to the up-regulation of hepatic OATPs.  PHARMACEUTICAL BIOLOGY,  60  (1): (359-373).  [PMID:35171063]
23. Shuaibing Liu, Ziteng Wang, Eric Chan, Yibo Zhao, Jian Kang, Xiaojian Zhang, Xin Tian.  (2022)  Inhibition of cytochrome P450 enzymes and uridine 5′-diphospho-glucuronosyltransferases by vicagrel in human liver microsomes: A prediction of potential drug-drug interactions.  CHEMICO-BIOLOGICAL INTERACTIONS,  352  (109775).  [PMID:34910929]
24. Yang Zhou, Fan Tong, Weilong Gu, Siqin He, Xiaotong Yang, Jiamei Li, Yue-Dong Gao, Huile Gao.  (2022)  Co-delivery of photosensitizer and diclofenac through sequentially responsive bilirubin nanocarriers for combating hypoxic tumors.  Acta Pharmaceutica Sinica B,  12  (1416).  [PMID:35530138]
25. Cong Pan, Libin Fu, Fenna Lide, Yaobin Ding, Chengjun Wang, Jia Huang, Shaobin Wang.  (2022)  Insights into bromate reduction by Fe(II): Multiple radicals generation and carbamazepine oxidation.  CHEMICAL ENGINEERING JOURNAL,  431  (133957).  [PMID:]
26. Jinbin Lin, Jing Zou, Hengyu Cai, Yixin Huang, Jiawen Li, Junyang Xiao, Baoling Yuan, Jun Ma.  (2021)  Hydroxylamine enhanced Fe(II)-activated peracetic acid process for diclofenac degradation: Efficiency, mechanism and effects of various parameters.  WATER RESEARCH,  207  (117796).  [PMID:34736001]
27. Xuefeng Wang,Hua Wang,Qin Jiang,Yong-Ill Lee,Shengyu Feng,Hong-Guo Liu.  (2017-07-18)  Highly selective and sensitive fluorogenic ferric probes based on aggregation-enhanced emission with -SiMe.  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy,  188  (202-207).  [PMID:28715687]
28. Zhen Chen,Shaoxiong He,Mingshan Zhu,Chaohai Wei.  (2019-12-26)  The effect of peroxymonosulfate in WS2 nanosheets for the removal of diclofenac: Information exposure and degradation pathway..  Chemosphere,  245  (125678-125678).  [PMID:31875574]
29. Wang, et al..  (2021)  Inhibition of human UDP-glucuronosyltransferase enzyme by belinostat: Implications for drug-drug interactions..  Toxicology Letters,  338  (51-57).  [PMID:33290829]

References

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19. Xin Liu, Peng Xu, Zhuoyu Yang, Pengfei Zhu, Lei Wang, Shiqi Xie.  (2022)  Catalytic oxidation of 4-acetamidophenol with Fe3+-enhanced Cu0 particles: In-site generation and activation of hydrogen peroxide.  JOURNAL OF HAZARDOUS MATERIALS,  436  (129291).  [PMID:35739796]
20. Peng Xu, Shiqi Xie, Xin Liu, Lei Wang, Xiangwen Jia, Chao Yang.  (2022)  Electrochemical enhanced heterogenous activation of peroxymonosulfate using CuFe2O4 particle electrodes for the degradation of diclofenac.  CHEMICAL ENGINEERING JOURNAL,  446  (136941).  [PMID:]
21. Nkoom Matthew, Lu Guanghua, Liu Jianchao.  (2022)  Chronic toxicity of diclofenac, carbamazepine and their mixture to Daphnia magna: a comparative two-generational study.  ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH,  29  (39): (58963-58979).  [PMID:35378650]
22. Ruifeng Liang, Wenjing Ge, Bingjie Li, Weifeng Cui, Xiaofan Ma, Yuying Pan, Gengsheng Li.  (2022)  Evodiamine decreased the systemic exposure of pravastatin in non-alcoholic steatohepatitis rats due to the up-regulation of hepatic OATPs.  PHARMACEUTICAL BIOLOGY,  60  (1): (359-373).  [PMID:35171063]
23. Shuaibing Liu, Ziteng Wang, Eric Chan, Yibo Zhao, Jian Kang, Xiaojian Zhang, Xin Tian.  (2022)  Inhibition of cytochrome P450 enzymes and uridine 5′-diphospho-glucuronosyltransferases by vicagrel in human liver microsomes: A prediction of potential drug-drug interactions.  CHEMICO-BIOLOGICAL INTERACTIONS,  352  (109775).  [PMID:34910929]
24. Yang Zhou, Fan Tong, Weilong Gu, Siqin He, Xiaotong Yang, Jiamei Li, Yue-Dong Gao, Huile Gao.  (2022)  Co-delivery of photosensitizer and diclofenac through sequentially responsive bilirubin nanocarriers for combating hypoxic tumors.  Acta Pharmaceutica Sinica B,  12  (1416).  [PMID:35530138]
25. Cong Pan, Libin Fu, Fenna Lide, Yaobin Ding, Chengjun Wang, Jia Huang, Shaobin Wang.  (2022)  Insights into bromate reduction by Fe(II): Multiple radicals generation and carbamazepine oxidation.  CHEMICAL ENGINEERING JOURNAL,  431  (133957).  [PMID:]
26. Jinbin Lin, Jing Zou, Hengyu Cai, Yixin Huang, Jiawen Li, Junyang Xiao, Baoling Yuan, Jun Ma.  (2021)  Hydroxylamine enhanced Fe(II)-activated peracetic acid process for diclofenac degradation: Efficiency, mechanism and effects of various parameters.  WATER RESEARCH,  207  (117796).  [PMID:34736001]
27. Xuefeng Wang,Hua Wang,Qin Jiang,Yong-Ill Lee,Shengyu Feng,Hong-Guo Liu.  (2017-07-18)  Highly selective and sensitive fluorogenic ferric probes based on aggregation-enhanced emission with -SiMe.  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy,  188  (202-207).  [PMID:28715687]
28. Zhen Chen,Shaoxiong He,Mingshan Zhu,Chaohai Wei.  (2019-12-26)  The effect of peroxymonosulfate in WS2 nanosheets for the removal of diclofenac: Information exposure and degradation pathway..  Chemosphere,  245  (125678-125678).  [PMID:31875574]
29. Wang, et al..  (2021)  Inhibition of human UDP-glucuronosyltransferase enzyme by belinostat: Implications for drug-drug interactions..  Toxicology Letters,  338  (51-57).  [PMID:33290829]

Solution Calculators