| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| D103949-25g | 25g | 3 | $9.90 | |
| D103949-100g | 100g | 3 | $11.90 | |
| D103949-500g | 500g | 3 | $20.90 |
| Synonyms | CCRIS 9480 | DIETHYL MALONATE | Ethyl methanedicarboxylate | EINECS 203-305-9 | Ethyl malonate (VAN) | Diethyl malonate, Vetec(TM) reagent grade, 98% | malonic acid-diethylester | Z104473166 | AMY37124 | Diethyl propanedioate | F1908-0063 | FT-0624843 | M |
|---|---|
| Specifications & Purity | ≥99% |
| Storage Temp | Room temperature |
| Shipped In | Normal |
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
| Pubchem Sid | 504751446 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/504751446 |
| IUPAC Name | diethyl propanedioate |
| INCHI | InChI=1S/C7H12O4/c1-3-10-6(8)5-7(9)11-4-2/h3-5H2,1-2H3 |
| InChi Key | IYXGSMUGOJNHAZ-UHFFFAOYSA-N |
| Canonical SMILES | CCOC(=O)CC(=O)OCC |
| Isomeric SMILES | CCOC(=O)CC(=O)OCC |
| WGK Germany | 1 |
| RTECS | OO0700000 |
| PubChem CID | 7761 |
| Molecular Weight | 160.17 |
| Beilstein | 774687 |
| Reaxy-Rn | 774687 |
Find and download the COA for your product by matching the lot number on the packaging.
23 results found
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 C2512313 | Certificate of Analysis | Nov 08, 2024 | D103949 |
| K2420458 | Certificate of Analysis | Nov 08, 2024 | D103949 |
| K2420277 | Certificate of Analysis | Nov 08, 2024 | D103949 |
| K2420276 | Certificate of Analysis | Nov 08, 2024 | D103949 |
| K2420275 | Certificate of Analysis | Nov 08, 2024 | D103949 |
| I2223483 | Certificate of Analysis | Jun 12, 2024 | D103949 |
| G2405192 | Certificate of Analysis | Mar 25, 2024 | D103949 |
| H2413064 | Certificate of Analysis | Oct 24, 2023 | D103949 |
| K2301473 | Certificate of Analysis | Oct 24, 2023 | D103949 |
| K2301444 | Certificate of Analysis | Oct 24, 2023 | D103949 |
| Solubility | Insoluble in water, soluble in ethanol, ether, trichloropropane, and benzene. |
|---|---|
| Sensitivity | Moisture sensitive. |
| Refractive Index | 1.4143 |
| Flash Point(°F) | 194 °F |
| Flash Point(°C) | 93℃ |
| Boil Point(°C) | 198-199°C |
| Melt Point(°C) | -50°C |
| Molecular Weight | 160.170 g/mol |
| XLogP3 | 1.000 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 4 |
| Rotatable Bond Count | 6 |
| Exact Mass | 160.074 Da |
| Monoisotopic Mass | 160.074 Da |
| Topological Polar Surface Area | 52.600 Ų |
| Heavy Atom Count | 11 |
| Formal Charge | 0 |
| Complexity | 125.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
| Pictogram(s) | GHS07 |
|---|---|
| Signal | Warning |
| Hazard Statements | H319:Causes serious eye irritation H335:May cause respiratory irritation |
| Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P405:Store locked up. P501:Dispose of contents/container to ... P271:Use only outdoors or in a well-ventilated area. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P337+P317:If eye irritation persists: Get medical help. P319:Get medical help if you feel unwell. |
| WGK Germany | 1 |
| RTECS | OO0700000 |
| Reaxy-Rn | 774687 |
| Merck Index | 3823 |
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| 1. Zhengrong Lin, Hongye Li, Jinpeng Zhang, Xiaomei Pei, Zhao Chen, Zhenggang Cui, Binglei Song. (2024) Toroidal micelles formed in viscoelastic aqueous solutions of a double-tailed surfactant with two quaternary ammonium head groups. Soft Matter, 20 (4): (804-812). [PMID:38168697] [10.1039/D3SM01132A] |
| 2. Linlin Lv, Weiwei Luo, Yixiao Zhou, Tiechun Li, Quanping Diao, Pinyi Ma, Daqian Song. (2023) A highly sensitive ratiometric fluorescent probe based on fluorescein coumarin for detecting hydrazine in actual water and biological samples. LUMINESCENCE, 38 (2): (159-165). [PMID:36601685] [10.1002/bio.4435] |
| 3. He Jiajian, Cheng Kai, Lin Ruijun, Su Qiuping, Li Yong, Ma Zhiping, Wang Shaoshun, Gu Yuxin, Lin Xiaofeng, Lin Wenjing, Yi Guobin. (2022) Preparation and properties of a novel coating based on bismaleimides via Michael addition reaction. Journal of Coatings Technology and Research, 19 (6): (1731-1741). [PMID:] [10.1007/s11998-022-00644-8] |
| 4. Huixiang Li, Peifang Yan, Bo-Qing Xu, Z. Conrad Zhang. (2022) Oxygen affinity of transition metal cations: A coherent descriptor elucidating catalytic oxygenate transformations. JOURNAL OF CATALYSIS, 412 (21). [PMID:] [10.1016/j.jcat.2022.05.015] |
| 5. Kun WANG, Er-Fei DONG, Min FANG, Ting CHEN, Wei-Ju ZHU, Cun LI. (2022) Construction of ratio fluorescence sensor based on CdTe quantum dots and benzocoumarin-3-carboxylic acid for Hg2+ detection. CHINESE JOURNAL OF ANALYTICAL CHEMISTRY, 50 (100070). [PMID:] [10.1016/j.cjac.2022.100070] |
| 6. Xiaojing Yang, Di-Feng Chen, Lin-Song Li, Xue-Jie Zhao, Mei-Xia Zhao. (2021) Mesoporous silica nanoparticles loaded with fluorescent coumarin-5-fluorouracil conjugates as mitochondrial-targeting theranostic probes for tumor cells. NANOTECHNOLOGY, 32 (45): (455101). [PMID:34340227] [10.1088/1361-6528/ac19d6] |
| 7. Fanyong Yan, Hao Zhang, Xing Li, Xiaodong Sun, Yingxia Jiang, Yali Cui. (2021) A fluorescein-coumarin based ratiometric fluorescent probe for detecting hydrazine and its real applications in cells imaging. TALANTA, 223 (121779). [PMID:33298284] [10.1016/j.talanta.2020.121779] |
| 8. Yue Wang, Huan Feng, Haibo Li, Xinyi Yang, Hongmin Jia, Wenjun Kang, Qingtao Meng, Zhiqiang Zhang, Run Zhang. (2020) A Copper (II) Ensemble-Based Fluorescence Chemosensor and Its Application in the ‘Naked–Eye’ Detection of Biothiols in Human Urine. SENSORS, 20 (5): (1331). [PMID:32121408] [10.3390/s20051331] |
| 9. Xinfeng Cheng, Xiuping Ju, Hongmei Du, Yan Zhang, Jinsheng Zhao, Yu Xie. (2018) Synthesis and characterization of novel donor–acceptor type electrochromic polymers containing diketopyrrolopyrrole as an acceptor and propylenedioxythiophene or indacenodithiophene as a donor. RSC Advances, 8 (41): (23119-23129). [PMID:35540135] [10.1039/C8RA03570A] |
| 10. Linlin Yang, Jun Zhao, Xinling Yu, Ruilong Zhang, Guangmei Han, Renyong Liu, Zhengjie Liu, Tingting Zhao, Ming-Yong Han, Zhongping Zhang. (2018) Dynamic mapping of spontaneously produced H2S in the entire cell space and in live animals using a rationally designed molecular switch. ANALYST, 143 (8): (1881-1889). [PMID:29560968] [10.1039/C7AN01802A] |
| 11. Xueyi Sun, Yu Wang, Xiaofeng Zhang, Shihong Zhang, Zhao Zhang. (2015) A new coumarin based chromo-fluorogenic probe for selective recognition of cyanide ions in an aqueous medium. RSC Advances, 5 (117): (96905-96910). [PMID:] [10.1039/C5RA14500G] |
| 12. Binglei Song, Zonghui Xu, Xiaona Yu, Shuyi Chen, Shunan Li, Rongzhen Shi, Zhenggang Cui. (2015) Synthesis and Solution Properties of a Double-Tailed Quaternary Ammonium Surfactant with a Protrudent Head Group. JOURNAL OF SURFACTANTS AND DETERGENTS, 18 (6): (1081-1088). [PMID:] [10.1007/s11743-015-1738-y] |
| 1. Edward J Hennessy,Stephen L Buchwald. (2002-02-14) A general and mild copper-catalyzed arylation of diethyl malonate.. Organic letters, 4 ((2)): (269-272). [PMID:11796067] |
| 2. Shengming Ma,Shichao Yu,Shaohu Yin. (2003-11-08) Studies on K2CO3-catalyzed 1,4-addition of 1,2-allenic ketones with diethyl malonate: controlled selective synthesis of beta,gamma-unsaturated enones and alpha-pyrones.. The Journal of organic chemistry, 68 ((23)): (8996-9002). [PMID:14604373] |
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| 5. Chunying Shu,Ting Cai,Liaosa Xu,Tianming Zuo,Jonathan Reid,Kim Harich,Harry C Dorn,Harry W Gibson. (2007-11-22) Manganese(III)-catalyzed free radical reactions on trimetallic nitride endohedral metallofullerenes.. Journal of the American Chemical Society, 129 ((50)): (15710-15717). [PMID:18027949] |
| 6. Hua Li,Joon Hee Hong. (2010-07-28) Synthesis and anti-HIV evaluation of new acyclic phosphonate nucleotide analogues and their bis(SATE) derivatives.. Nucleosides, nucleotides & nucleic acids, 29 ((8)): (581-590). [PMID:20661812] |
| 7. Adel A A Emara,Azza A A Abu-Hussein,Ahmed A Taha,Nelly H Mahmoud. (2010-08-07) Spectroscopic, solvent influence and thermal studies of ternary copper(II) complexes of diester and dinitrogen base ligands.. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 77 ((3)): (594-604). [PMID:20688561] |
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| 9. Stephanie Oerum,Peter Krabbe,Magnus Schau-Magnussen,Søren Furbo,Jesper Bendix,Anders Hammershøi. (2012-11-22) Highly stereoselective, cobalt(III)-directed Mannich additions in water yielding α-methylamino acid products.. Dalton transactions (Cambridge, England : 2003), 42 ((1)): (292-298). [PMID:23168834] |
| 10. Shigeo Hayashi, Naomi Ueno, Akio Murase, Junji Takada,. (2014-02-13) Design, synthesis and structure-activity relationship studies of novel and diverse cyclooxygenase-2 inhibitors as anti-inflammatory drugs.. Journal of enzyme inhibition and medicinal chemistry, 29 ((6)): ( 846-867 ). [PMID:24517373] |
| 11. D Timothy Anstine,David A Lightner. (2014-08-12) Intramolecular Hydrogen Bonding and Linear Pentapyrrole Conformation.. Monatshefte fur chemie, 145 ((7)): (1117-1135). [PMID:25110361] |
| 12. Kye Chung Park,Toni M Withers,David Maxwell Suckling. (2015-05-06) Identification of olfactory receptor neurons in Uraba lugens (Lepidoptera: Nolidae) and its implications for host range.. Journal of insect physiology, 78 (33-46). [PMID:25937382] |
| 13. Faqiang Leng,Iann C Gerber,Pierre Lecante,Ahmed Bentaleb,Antonio Muñoz,Beatriz M Illescas,Nazario Martín,Georgian Melinte,Ovidiu Ersen,Hervé Martinez,M Rosa Axet,Philippe Serp. (2017-05-26) Hexakis [60]Fullerene Adduct-Mediated Covalent Assembly of Ruthenium Nanoparticles and Their Catalytic Properties.. Chemistry (Weinheim an der Bergstrasse, Germany), 23 ((54)): (13379-13386). [PMID:28543998] |
| 14. Sau Fan Yip,Hong Yee Cheung,Zhongyuan Zhou,Fuk Yee Kwong. (2007-07-20) Room-temperature copper-catalyzed alpha-arylation of malonates.. Organic letters, 9 ((17)): (3469-3472). [PMID:17637034] |
| 15. Alessandro Marrone,Andrea Renzetti,Paolo De Maria,Stéphane Gérard,Janos Sapi,Antonella Fontana,Nazzareno Re. (2009-09-25) Condensation of beta-diester titanium enolates with carbonyl substrates: a combined DFT and experimental investigation.. Chemistry (Weinheim an der Bergstrasse, Germany), 15 ((43)): (11537-11550). [PMID:19777518] |
| 16. Zhengrong Lin, Hongye Li, Jinpeng Zhang, Xiaomei Pei, Zhao Chen, Zhenggang Cui, Binglei Song. (2024) Toroidal micelles formed in viscoelastic aqueous solutions of a double-tailed surfactant with two quaternary ammonium head groups. Soft Matter, 20 (4): (804-812). [PMID:38168697] [10.1039/D3SM01132A] |
| 17. Linlin Lv, Weiwei Luo, Yixiao Zhou, Tiechun Li, Quanping Diao, Pinyi Ma, Daqian Song. (2023) A highly sensitive ratiometric fluorescent probe based on fluorescein coumarin for detecting hydrazine in actual water and biological samples. LUMINESCENCE, 38 (2): (159-165). [PMID:36601685] [10.1002/bio.4435] |
| 18. He Jiajian, Cheng Kai, Lin Ruijun, Su Qiuping, Li Yong, Ma Zhiping, Wang Shaoshun, Gu Yuxin, Lin Xiaofeng, Lin Wenjing, Yi Guobin. (2022) Preparation and properties of a novel coating based on bismaleimides via Michael addition reaction. Journal of Coatings Technology and Research, 19 (6): (1731-1741). [PMID:] [10.1007/s11998-022-00644-8] |
| 19. Huixiang Li, Peifang Yan, Bo-Qing Xu, Z. Conrad Zhang. (2022) Oxygen affinity of transition metal cations: A coherent descriptor elucidating catalytic oxygenate transformations. JOURNAL OF CATALYSIS, 412 (21). [PMID:] [10.1016/j.jcat.2022.05.015] |
| 20. Kun WANG, Er-Fei DONG, Min FANG, Ting CHEN, Wei-Ju ZHU, Cun LI. (2022) Construction of ratio fluorescence sensor based on CdTe quantum dots and benzocoumarin-3-carboxylic acid for Hg2+ detection. CHINESE JOURNAL OF ANALYTICAL CHEMISTRY, 50 (100070). [PMID:] [10.1016/j.cjac.2022.100070] |
| 21. Xiaojing Yang, Di-Feng Chen, Lin-Song Li, Xue-Jie Zhao, Mei-Xia Zhao. (2021) Mesoporous silica nanoparticles loaded with fluorescent coumarin-5-fluorouracil conjugates as mitochondrial-targeting theranostic probes for tumor cells. NANOTECHNOLOGY, 32 (45): (455101). [PMID:34340227] [10.1088/1361-6528/ac19d6] |
| 22. Fanyong Yan, Hao Zhang, Xing Li, Xiaodong Sun, Yingxia Jiang, Yali Cui. (2021) A fluorescein-coumarin based ratiometric fluorescent probe for detecting hydrazine and its real applications in cells imaging. TALANTA, 223 (121779). [PMID:33298284] [10.1016/j.talanta.2020.121779] |
| 23. Yue Wang, Huan Feng, Haibo Li, Xinyi Yang, Hongmin Jia, Wenjun Kang, Qingtao Meng, Zhiqiang Zhang, Run Zhang. (2020) A Copper (II) Ensemble-Based Fluorescence Chemosensor and Its Application in the ‘Naked–Eye’ Detection of Biothiols in Human Urine. SENSORS, 20 (5): (1331). [PMID:32121408] [10.3390/s20051331] |
| 24. Xinfeng Cheng, Xiuping Ju, Hongmei Du, Yan Zhang, Jinsheng Zhao, Yu Xie. (2018) Synthesis and characterization of novel donor–acceptor type electrochromic polymers containing diketopyrrolopyrrole as an acceptor and propylenedioxythiophene or indacenodithiophene as a donor. RSC Advances, 8 (41): (23119-23129). [PMID:35540135] [10.1039/C8RA03570A] |
| 25. Linlin Yang, Jun Zhao, Xinling Yu, Ruilong Zhang, Guangmei Han, Renyong Liu, Zhengjie Liu, Tingting Zhao, Ming-Yong Han, Zhongping Zhang. (2018) Dynamic mapping of spontaneously produced H2S in the entire cell space and in live animals using a rationally designed molecular switch. ANALYST, 143 (8): (1881-1889). [PMID:29560968] [10.1039/C7AN01802A] |
| 26. Xueyi Sun, Yu Wang, Xiaofeng Zhang, Shihong Zhang, Zhao Zhang. (2015) A new coumarin based chromo-fluorogenic probe for selective recognition of cyanide ions in an aqueous medium. RSC Advances, 5 (117): (96905-96910). [PMID:] [10.1039/C5RA14500G] |
| 27. Binglei Song, Zonghui Xu, Xiaona Yu, Shuyi Chen, Shunan Li, Rongzhen Shi, Zhenggang Cui. (2015) Synthesis and Solution Properties of a Double-Tailed Quaternary Ammonium Surfactant with a Protrudent Head Group. JOURNAL OF SURFACTANTS AND DETERGENTS, 18 (6): (1081-1088). [PMID:] [10.1007/s11743-015-1738-y] |
